| Orelabrutinib Followed by Response-adapted Ultra-low Dose 4Gy Radiation as First-line Treatment of MALT Lymphoma (NCT06583837) | Fudan University | 2024-09-10 |
| TIL Therapy Combined With Pembrolizumab for Advanced or Metastatic Refractory Stomach and Esophageal Cancer (NCT06532799) | Essen Biotech | 2024-09-10 |
| A Study to Determine the Safety and Efficacy of Bevacizumab Administered Via Injection Into the Shoulder Joint of Participants With Adhesive Capsulitis (Frozen Shoulder) (NCT06976671) | Macquarie University, Australia | 2024-09-10 |
| Adebrelimab and Chidamide for Pancreatic Cancer (NCT06584227) | Liu Xiufeng | 2024-09-10 |
| Evaluating Efgartigimod in Patients With Guillain-Barré Syndrome (NCT05701189) | Chafic Karam | 2024-09-10 |
| RVU120 for Treatment of Anemia in Patients With Lower-risk Myelodysplastic Neoplasms (NCT06243458) | GCP-Service International West GmbH | 2024-09-10 |
| Phase II Clinical Trial of PD-L1 in Combination With Vinorelbine + Cyclophosphamide + Capecitabine (VEX) Metronomic Chemotherapy With or Without Radiotherapy for Advanced Triple-negative Breast Cancer. (NCT06771609) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2024-09-10 |
| A Study of Fianlimab, Cemiplimab, and Ipilimumab in People With Melanoma (NCT06594991) | Memorial Sloan Kettering Cancer Center | 2024-09-10 |
| Efficacy and Safety of SR1375 in Adult Patients With CAP (NCT06577558) | Shanghai SIMR Biotechnology Co., Ltd. | 2024-09-10 |
| A Study of Anti-PD-1 and LAG-3 Bispecific Antibody(AK129) Combined With Chemotherapy With or Without Cadonilimab in the First-line Treatment of Unresectable Locally Advanced or Metastatic G/ GEJ Adenocarcinoma (NCT06586294) | Akeso | 2024-09-10 |
| PH009-1 in Patients With EGFR Mutation Locally Advanced or Metastatic Non-small Cell Lung Cancer (NSCLC) (NCT06590194) | Suzhou Puhe Pharmaceutical Technology Co., LTD | 2024-09-10 |
| A Phase 2b Study of Zagociguat in Patients With MELAS (NCT06402123) | Tisento Therapeutics | 2024-09-10 |
| Efficacy and Safety of Gemlapodect (NOE-105) in Adults and Adolescents With Tourette Syndrome (NCT06315751) | Noema Pharma AG | 2024-09-10 |
| Feasibility of 18F-Fluciclovine PET/CT to Identify Brain Metastasis (NCT06055790) | University of Arizona | 2024-09-10 |
| LIFT: Life Improvement Trial (NCT06366724) | Brigham and Women's Hospital | 2024-09-10 |
| A Phase II/III Study of Linperlisib Plus CHOP Versus CHOP in Patients With Newly Diagnosed Peripheral T Cell Lymphoma (NCT06548347) | Shanghai YingLi Pharmaceutical Co. Ltd. | 2024-09-10 |
| Intravitreal Faricimab in Patients With Refractory Macular Edema (NCT07093385) | University of Baghdad | 2024-09-10 |
| Enfortumab Vedotin and Stereotactic Radiation for Localized, Cisplatin Ineligible Muscle Invasive Bladder Cancer (NCT06394570) | University of Texas Southwestern Medical Center | 2024-09-10 |
| Neoadjuvant Chemotherapy With WH002 in Women With HER2-negative Breast Cancer (NCT06513364) | Beijing Wehand-Bio Pharmaceutical Co., Ltd | 2024-09-10 |
| Piperacillin/Tazobactam Versus ceftriAxone and Metronidazole for Children With Perforated Appendicitis (ALPACA) (NCT05943223) | McMaster Children's Hospital | 2024-09-09 |
| A Study of Vemurafenib and Obinutuzumab Compared to Cladribine and Rituximab in People With Hairy Cell Leukemia (HCL) (NCT06561360) | Memorial Sloan Kettering Cancer Center | 2024-09-09 |
| A Prospective Comparative Study of Autologous Bone Marrow-Derived and Adipose Tissue-Derived Mesenchymal Stem Cells Versus Platelet-Rich Plasma and Standard Therapy in Patients With Organic Erectile Dysfunction (NCT07544537) | National Scientific Medical Center, Kazakhstan | 2024-09-09 |
| Topical Tacrolimus for Breast Cancer-related Lymphedema (NCT06306274) | Odense University Hospital | 2024-09-09 |
| EIS-12656 as Single Agent and in Combination in Patients With Specified Solid Tumors (NCT06525298) | Eisbach Bio GmbH | 2024-09-09 |
| Dex +/- Caffeine Sedation in a Post-MRI Recovery in a Pediatric Population (NCT06538584) | University of Chicago | 2024-09-09 |
| Efficacy of MI078 Capsules in Treating Postpartum Depression (NCT06963580) | Nanjing Minova Pharmaceutical Co., Ltd. | 2024-09-09 |
| Combination Adjunctive Therapy to Address Multiple Metabolic Imbalances in Type 1 Diabetes (NCT05696366) | University of California, San Diego | 2024-09-09 |
| Mosunetuzumab and Polatuzumab Vedotin for the Treatment of Patients With Relapsed or Refractory Grade 1-3a Follicular Lymphoma (NCT06453044) | City of Hope Medical Center | 2024-09-09 |
| Study of INV-102 Ophthalmic Solution in Adults With Diabetic Macular Edema Associated With Non-proliferative Diabetic Retinopathy (NCT06599684) | Invirsa, Inc. | 2024-09-07 |
| Comparison of Early Proton Pump Inhibitor Initiation Versus Usual Care on Acute Kidney Injury in Hemorrhagic Shock Patients (NCT06531642) | The University of Texas Health Science Center, Houston | 2024-09-07 |
| a Chronobiological Treatment Combining Evening Melatonin and Morning Light Therapy in Idiopathic Hypersomnia: a Prospective, Double Bind, Randomized, Placebo-controlled -Trial (NCT06252571) | University Hospital, Strasbourg, France | 2024-09-07 |
| A Safety and Efficacy Study of Different Doses of Oxfendazole Compared to a Single Dose of Albendazole to Treat Trichuris Trichiura Infection in Adults (NCT04713787) | Asociacion Benefica Prisma | 2024-09-07 |
| Anorectal Manometery in Pediatric Chronic Refractory Constipation (NCT06543979) | Ain Shams University | 2024-09-07 |
| CK-0045 Proof-of-concept Study in Participants With Overweight / Obesity and Type 2 Diabetes (NCT06611930) | Cytoki Pharma | 2024-09-06 |
| Novel Intervention for Chronic Complex TBI in OEF/OIF/OND Veterans (NCT05671692) | Christine Marx, MD | 2024-09-06 |
| Relugolix and Enzalutamide in Combination With Radiation Therapy for the Treatment of Very High Risk Prostate Cancer, OPTIMAL Trial (NCT06499870) | Sean Sachdev | 2024-09-06 |
| Online Adaptive Radiotherapy for Cervical Cancer (NCT06562166) | Peking Union Medical College Hospital | 2024-09-05 |
| Psilocybe Cubensis Mushrooms With or Without Fluoxetine for Refractory Depression (NCT06898606) | Federal University of Latin American Integration | 2024-09-05 |
| Classifying for HER2 Dependence to De-Escalate Neoadjuvant Chemotherapy in Patients With HER2+ Early Breast Cancer Undergoing HER2 Double-Blockade (NCT06068985) | Latin American Cooperative Oncology Group | 2024-09-05 |
| Neoadjuvant INBRX-106 in Combination With Pembrolizumab for Stage II/III TNBC Patients (NCT06353997) | Providence Health & Services | 2024-09-05 |
| A Study to Test Whether BI 1819479 Improves Lung Function in People With Idiopathic Pulmonary Fibrosis (IPF) (NCT06335303) | Boehringer Ingelheim | 2024-09-05 |
| Study to Examine the Effects of Oral Fenretinide (NCT06528457) | Island Pharmaceuticals | 2024-09-05 |
| Pinoxin for the Prevention of Radiation-Induced Skin Injury (NCT07545720) | Fudan University | 2024-09-05 |
| Study of TTX-MC138 in Subjects With Advanced Solid Tumors (NCT06260774) | TransCode Therapeutics | 2024-09-05 |
| A Study to Assess the Efficacy and Safety of WSD0922-FU in Patients With EGFRm+ Advanced Non-small Cell Lung Cancer (NCT06631989) | Wayshine Biopharm, Inc. | 2024-09-04 |
| A Study of Rapcabtagene Autoleucel in Active, Refractory Systemic Lupus Erythematosus (SLE) or Lupus Nephritis (LN) Patients (AUTOGRAPH - SLE/LN) (NCT06581198) | Novartis Pharmaceuticals | 2024-09-04 |
| Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease (NCT06548542) | AbbVie | 2024-09-04 |
| Mucoadhesive Modified-Release Formulations for the Topical Treatment of Symptomatic Oral Lichen Planus (NCT07100613) | University of Palermo | 2024-09-04 |
| Using Navigation to Improve Accuracy of Maxillary Balloon Sinusotomy (NCT06567821) | Cedars-Sinai Medical Center | 2024-09-04 |
| A Study of TX000045 in Patients With Pulmonary Hypertension Secondary to Heart Failure With Preserved Ejection Fraction (the APEX Study) (NCT06616974) | Tectonic Therapeutic | 2024-09-04 |
| Next Generation Rocklatan (NCT06441643) | Alcon Research | 2024-09-04 |
| Evaluation of the Efficacy and Safety of Furmonertinib Combined with Bevacizumab As First-Line Treatment for EGFR-Positive Non-Small Cell Lung Cancer with Brain Metastases: a Single-Arm, Open-Label, Prospective Phase II Clinical Study (NCT06728865) | Li-kun Chen | 2024-09-04 |
| Study of the Efficacy and Safety of Etanercept Treatment in Patients With SAPHO Syndrome (NCT06011889) | National Institute of Geriatrics, Rheumatology and Rehabilitation, Poland | 2024-09-04 |
| A Study of IBI311 in Subjects With Inactive or Active Thyroid Eye Disease (NCT06525506) | Innovent Biologics (Suzhou) Co. Ltd. | 2024-09-04 |
| Anti-CD19 Chimeric Antigen Receptor T-Cell Immunotherapy for Leukemias (NCT06364423) | National Cancer Institute (NCI) | 2024-09-03 |
| Neoadjuvant Chemoimmunotherapy and Extrafascial Hysterectomy for IB2 Cervical Cancer (NCT06289751) | Tongji Hospital | 2024-09-03 |
| Pyridostigmine Efficacy and Safety for Treatment of Ileus After Colorectal Surgery (NCT05334485) | Stefan Holubar MD MS FACS, FASCRS | 2024-09-03 |
| Neoadjuvant Adebrelimab Plus Chemotherapy for Esophageal Cancer: A Clinical Study (NCT07437898) | The Affiliated Hospital of Putian University | 2024-09-03 |
| Gemcitabine + Docetaxel + Toripalimab Induction in Epstein-Barr Virus (EBV) Associated Nasopharyngeal Carcinoma(NPC) (NCT06592599) | Stanford University | 2024-09-03 |
| Intraoperative Use of Oxygen Saturation Imaging to Assess Intestinal Perfusion (NCT07587619) | University of Southern California | 2024-09-03 |
| Phase 2 Study Evaluating the Safety and Efficacy of Microneedle-mediated Delivery of Doxorubicin (D-MNA) in Patients With Nodular Basal Cell Carcinoma. (NCT06608238) | SkinJect, Inc. | 2024-09-03 |
| Evaluation of the Efficacy of 0.08% Tacrolimus Nanoencapsulated Aqueous Solution Spray Vs. 0.1% Free Tacrolimus Commercial Ointment in the Treatment of Oral Lichen Planus (NCT06591884) | Hospital de Clinicas de Porto Alegre | 2024-09-03 |
| First-in-human Study of DB-1419 for Advanced/Metastatic Solid Tumors (NCT06554795) | DualityBio Inc. | 2024-09-03 |
| A Phase 2 Study of SSGJ-707 in Metastatic Colorectal Cancer Patients (NCT06493760) | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | 2024-09-03 |
| Denosumab for Type 1 Diabetes (NCT06524960) | City of Hope Medical Center | 2024-09-03 |
| Study to Assess Efficacy, Safety, Tolerability, Pharmacokinetics (PK), and Pharmacodynamics (PD) of Obeticholic Acid (OCA) Compared to Placebo in Pediatric Participants With Biliary Atresia, Post-hepatoportoenterostomy (NCT06121375) | Intercept Pharmaceuticals | 2024-09-02 |
| Ropidoxuridine as a Radiosensitizer in Newly Diagnosed IDH-Wildtype Glioblastoma With Unmethylated MGMT Promoter (NCT06359379) | Shuttle Pharmaceuticals, Inc. | 2024-09-02 |
| A Trial to Evaluate Safety and Efficacy of a Product Named VGN-R09b in Patients With Parkinson's Disease (NCT06480461) | Shanghai Vitalgen BioPharma Co., Ltd. | 2024-09-02 |
| Pharmacoscopy-guided Clinical Standard-of-care in r/r AML (NCT06138990) | ETH Zurich | 2024-09-02 |
| Pharmacokinetics and Efficacy of Multiple Dosing of LP-98 for Injection in HIV-infected Patients (NCT06560489) | Shanxi Kangbao Biological Product Co., Ltd. | 2024-09-02 |
| Proximod, a Selective Sphingosine-1-phosphate Receptor 1 Modulator in Patients With Moderate-to-severe Active Rheumatoid Arthritis: a Double-blind, Randomised, Placebo-controlled, Phase 2 Trial. (NCT07335952) | Peking University People's Hospital | 2024-09-02 |
| Zanubrutinib With Obinutuzumab in Untreated Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (NCT06544785) | PETHEMA Foundation | 2024-09-02 |
| Dose Escalation Study of ZG006 in Participants With Advanced Small Cell Lung Cancer or Neuroendocrine Carcinoma, Followed by Dose Expansion Study in Participants With Advanced Small Cell Lung Cancer (NCT06283719) | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | 2024-09-02 |
| Long-Term Safety and Efficacy of HB0034 in Subjects With Generalized Pustular Psoriasis (NCT06477536) | Shanghai Huaota Biopharmaceutical Co., Ltd. | 2024-09-02 |
| Phase II Clinical Study of GemOX Hepatic Arterial Infusion Combined with Lenvatinib and Toripalimab for Advanced and Unresectable Intrahepatic Cholangiocarcinoma and Gallbladder Cancer (NCT06852287) | Tianjin Medical University Cancer Institute and Hospital | 2024-09-01 |
| "Selinexor+Pegaspargase+Dexamethasone"in Ⅰ/Ⅱ NKTCL (NCT06559553) | Mingzhi Zhang | 2024-09-01 |
| Safety and Efficacy of Cryoablation With Karelizumab and Apatinib for Multiple Lung Cancers (NCT06607770) | Zhou Chengzhi | 2024-09-01 |
| Polypill Versus Metformin in New Onset Type 2 Diabetes (NCT05833958) | George Medicines PTY Limited | 2024-09-01 |
| Chidamide and PD-1 Inhibitor Plus Anlotinib for HER2-low Breast Cancer That Has Spread or Cannot be Surgically Removed (NCT06547476) | Guangdong Provincial People's Hospital | 2024-09-01 |
| EGCG for Hepatocellular Carcinoma Chemoprevention (NCT06015022) | University of Texas Southwestern Medical Center | 2024-09-01 |
| Efficacy of Fentanyl Soaked Nasal Packs on Postoperative Pain in Nasal Surgeries. (NCT06531759) | Assiut University | 2024-09-01 |
| Comparison Between Treatments of Oligohydramnios (NCT07135037) | Kafrelsheikh University | 2024-09-01 |
| Psilocybin-assisted Therapy for Alcohol Use Disorder (NCT06444243) | University of Sydney | 2024-09-01 |
| Golidocitinib Plus CHOP in Newly Diagnosed PTCL (NCT06739265) | Peking Union Medical College Hospital | 2024-09-01 |
| CAR T-cell Therapy in Combination With Glofitamab for Relapsed/Refractory Large B-Cell Lymphoma With High-Risk Prognostic Factors (NCT06567366) | Ruijin Hospital | 2024-09-01 |
| Ph I/II Study of CAR19 Regulatory T Cells (CAR19-tTreg) for R/R CD19+ B-ALL (NCT05114837) | Masonic Cancer Center, University of Minnesota | 2024-09-01 |
| Studying Topiramate for Re-Activating the HIV-1 Reservoir (NCT06282783) | Erasmus Medical Center | 2024-09-01 |
| Prospective Clinical Investigation on Infection as a Cause of Chronic Subdural Hematoma. (NCT07556991) | University of Rostock | 2024-09-01 |
| Low Dose Atropine Eye Drops in Myopic Egyptian Children (NCT06265454) | Ain Shams University | 2024-09-01 |
| Sm-p80 Schistosomiasis Challenge Study (NCT05999825) | Leiden University Medical Center | 2024-09-01 |
| The Effect of Inhaled Nitric Oxide on Dyspnea and Exercise Tolerance in Interstitial Lung Disease. (NCT04181359) | University of Alberta | 2024-09-01 |
| Hepatic Arterial Infusion Chemotherapy With Lipiodol Embolization in Advanced Hepatocellular Carcinoma (NCT06632717) | National Taiwan University Hospital | 2024-09-01 |
| Efficacy of Injectable Gentamicin in Hereditary Ichthyosis (NCT06362447) | University Hospital, Toulouse | 2024-09-01 |
| Niraparib and Temozolomide in Patients Glioblastoma (NCT06258018) | Armando Santoro, MD | 2024-09-01 |
| Low-dose Gemcitabine and Cisplatin and PD-1/PD-L1 Antibody Therapy in Intrahepatic Cholangiocarcinoma (NCT06567600) | Third Affiliated Hospital, Sun Yat-Sen University | 2024-09-01 |
| Effects of the Adjunctive Use of Hyaluronic Acid-based Gel With Coranally Advanced Flap in the Gingival Recession (NCT07437885) | Ordu University | 2024-09-01 |
| Imaging Depression in Parkinson's Disease (NCT06402955) | Yale University | 2024-09-01 |
| Study of Liver Fibrosis Stage Assessment by Fibroblast Activation Protein Imaging in Patients With Biopsy for Suspected or Proven Nonalcoholic Steatohepatitis (NCT06160271) | Central Hospital, Nancy, France | 2024-09-01 |
| VA as Maintenance Therapy Post Allo-HSCT in MDS and AML (NCT06598384) | Navy General Hospital, Beijing | 2024-09-01 |
| Does Human Skeletal Muscle Possess an Epigenetic Memory of Testosterone? (NCT05964920) | Norwegian School of Sport Sciences | 2024-09-01 |