| Neoajuvant Tislelizumab Combined with Chemotherapy for Initially Unresectable Stage IIIA/N2 Non-small Cell Lung Cancer (NCT06614231) | Sun Yat-sen University | 2024-09-20 |
| KYSA-7: A Study of Anti-CD19 CAR T-Cell Therapy, in Subjects With Refractory Primary and Secondary Progressive Multiple Sclerosis (NCT06384976) | Kyverna Therapeutics | 2024-09-20 |
| CHG Combined With Venetoclax and Azacytidine in Newly Diagnosed AML (NCT06470841) | Navy General Hospital, Beijing | 2024-09-20 |
| Study of CD388 for the Prevention of Influenza in Subjects Not at Risk for Influenza Complications (NCT06609460) | Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 2024-09-20 |
| A Study of A166 in Patients With HER2-Positive Unresectable or Metastatic Breast Cancer (NCT07299825) | Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. | 2024-09-20 |
| PET Scan Study to Detect Prostate Cancer in Patients with Early PSA Recurrence (NCT06617481) | AdventHealth | 2024-09-20 |
| Neoadjuvant SHR-A1811 Plus Adebrelimab in HR Negative/Low & HER2 Low Breast Cancer Patients (NCT06592625) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2024-09-20 |
| Substudy 06C: A Study of Investigational Agents With Pembrolizumab (MK-3475) and Chemotherapy in Participants With First-Line Locally Advanced Unresectable/Metastatic Gastroesophageal Adenocarcinoma (MK-3475-06C/KEYMAKER-U06) (NCT06469944) | Merck Sharp & Dohme LLC | 2024-09-20 |
| Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed). (NCT06607692) | Fundación de investigación HM | 2024-09-20 |
| Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY) (NCT06633016) | Autobahn Therapeutics, Inc. | 2024-09-20 |
| RVU120 in Patients With Intermediate or High-risk, Primary or Secondary Myelofibrosis (NCT06397313) | Ryvu Therapeutics SA | 2024-09-19 |
| Clinical Study of the Efficacy and Safety of SHR-1819 Injection in Adult Patients With Prurigo Nodularis (NCT06554509) | Guangdong Hengrui Pharmaceutical Co., Ltd | 2024-09-19 |
| XL092 (Zanzalintinib) for the Treatment of Patients With Metastatic or Unresectable Leiomyosarcoma, Bone Sarcoma or Translocation-associated Soft Tissue Sarcoma (NCT06571734) | Northwestern University | 2024-09-19 |
| CYTALUX™for the Intraoperative Imaging of Prostate Cancer (NCT06434909) | Indiana University | 2024-09-19 |
| Cadonilimab Combined With S-1 or Capecitabine as Second-line Treatment for Advanced Pancreatic Cancer (NCT06532617) | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 2024-09-19 |
| (2R,6R)-Hydroxynorketamine for the Treatment of Neuropathic Pain (NCT05864053) | Rush University Medical Center | 2024-09-19 |
| A Long-term Extension Study of JNJ-81201887 (AAVCAGsCD59) Parent Studies in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD) (NCT06635148) | Janssen Research & Development, LLC | 2024-09-19 |
| RSV Vaccination in Immunocompromised Patients. (NCT06597916) | Medical University of Vienna | 2024-09-19 |
| Efficacy and Safety of TJ0113 Capsule in Patients With Parkinson's Disease (NCT06596005) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2024-09-18 |
| Radiation Prior to TKI to Delay Progression in Advanced Driver-Mutated Non-small Cell Lung Cancers (RadiaNCe Lung X) (NCT06305715) | Medical College of Wisconsin | 2024-09-18 |
| Emapalumab Prevention of CAR-T Cell Associated Toxicities (NCT06550141) | Marcela V. Maus, M.D.,Ph.D. | 2024-09-18 |
| NS-050/NCNP-03 in Boys With DMD (Meteor50) (NCT06053814) | NS Pharma, Inc. | 2024-09-18 |
| Soy Isoflavones For Inner City Infants At Risk For Asthma (SIRA) Study (NCT05667701) | Rajesh Kumar | 2024-09-18 |
| Pacritinib in CMML (NCT06159491) | Douglas Tremblay | 2024-09-18 |
| Intranasal Oxytocin in Youth With Autism (NCT05934812) | Oslo University Hospital | 2024-09-18 |
| A Study to Evaluate Safety, PK, PD and Efficacy of AZD5492, a T Cell-engaging Antibody Targeting CD20 in Subjects With R/R B-Cell Malignancies. (NCT06542250) | AstraZeneca | 2024-09-18 |
| Vorinostat and 177Lu-PSMA-617 for the Treatment of PSMA-Low Metastatic Castration-Resistant Prostate Cancer (NCT06145633) | Fred Hutchinson Cancer Center | 2024-09-18 |
| Single Participant Study of an Experimental ASO Treatment for TUBB4A-related Leukodystrophy (NCT06369974) | Massachusetts General Hospital | 2024-09-18 |
| A Trial to Learn if Fianlimab and Cemiplimab Are Safe and Work Better Than Anti-PD1 Alone in Adult Participants With Resectable Stage 3 or 4 Melanoma (NCT06190951) | Regeneron Pharmaceuticals | 2024-09-18 |
| Study of Bepirovirsen in Participants Living With Human Immunodeficiency Virus and Chronic Hepatitis B Virus Infection (B-Focus) (NCT06497504) | GlaxoSmithKline | 2024-09-17 |
| INDV-6001 Multiple-Dose Pharmacokinetic Study (NCT06576843) | Indivior Inc. | 2024-09-17 |
| IV vs Epidural Opioids + Epidural Local Anesthetic for Laparotomy Analgesia (NCT06559969) | University of Iowa | 2024-09-17 |
| A Clinical Study to Evaluate DNTH103 in Adults With Multifocal Motor Neuropathy (NCT06537999) | Dianthus Therapeutics | 2024-09-17 |
| A Study of Obexelimab in Patients With Systemic Lupus Erythematosus (NCT06559163) | Zenas BioPharma (USA), LLC | 2024-09-17 |
| Study of FIH of STX-241 in Locally Advanced or Metastatic NSCLC Resistant to EGFR TKIs (NCT06567015) | Pierre Fabre Medicament | 2024-09-17 |
| Cannabis for Palliative Care in Cancer (NCT06266611) | University of Colorado, Boulder | 2024-09-16 |
| Evaluating the Efficacy and Safety of HSK21542 Injection in Chemotherapy-induced Nausea and Vomiting (NCT06593782) | First Affiliated Hospital of Wenzhou Medical University | 2024-09-16 |
| Efficacy, Safety, and Tolerability of SR750 in Patients With Trigeminal Neuralgia (NCT06571448) | Shanghai SIMR Biotechnology Co., Ltd. | 2024-09-16 |
| A Proof-of-Concept Study to Learn Whether Linvoseltamab Can Eliminate Abnormal Plasma Cells That May Lead to Multiple Myeloma in Adult Patients With High-Risk Monoclonal Gammopathy of Undetermined Significance or Non-High-Risk Smoldering Multiple Myeloma (NCT06140524) | Regeneron Pharmaceuticals | 2024-09-16 |
| A Study of Ciltacabtagene Autoleucel and Talquetamab for the Treatment of Participants With High-Risk Multiple Myeloma (NCT06550895) | Janssen Research & Development, LLC | 2024-09-16 |
| Sertraline vs. Placebo in the Treatment of Anxiety in Children and AdoLescents With NeurodevelopMental Disorders (NCT06081348) | Holland Bloorview Kids Rehabilitation Hospital | 2024-09-16 |
| Study of Cryopreserved AURN001 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction (NCT06630169) | Aurion Biotech | 2024-09-16 |
| Medical Cannabis in Patients With Advanced Pancreatic and Colorectal Cancer (NCT06605430) | HealthPartners Institute | 2024-09-16 |
| A Study to Evaluate the Efficacy and Safety of AVTX-009 in Patients With Moderate to Severe Hidradenitis Suppurativa (NCT06603077) | Avalo Therapeutics, Inc. | 2024-09-16 |
| Dose-Reduced Docetaxel With Cyclophosphamide for the Treatment of Vulnerable Older Women With Stage I-III HER2 Negative Breast Cancer, the DOROTHY Trial (NCT06042569) | City of Hope Medical Center | 2024-09-16 |
| Artificial Intelligence to Personalize Prostate Cancer Treatment (the HypoElect Trial) (NCT06582446) | German Oncology Center, Cyprus | 2024-09-16 |
| Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC (NCT06567743) | CG Oncology, Inc. | 2024-09-16 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of ASC30 Injection in Participants With Obesity (NCT06679959) | Ascletis Pharma (China) Co., Limited | 2024-09-16 |
| A Phase 1/2 Trial of SP-101 for the Treatment of Cystic Fibrosis (CF) (NCT06526923) | Spirovant Sciences, Inc. | 2024-09-16 |
| Neoadjuvant Immune Checkpoint Blockade + a Prebiotic Food-enriched Dietary Intervention to Optimize Immune Response in Melanoma: NEO-PreFED (NCT06548789) | M.D. Anderson Cancer Center | 2024-09-16 |
| Oxygen as an Acute Treatment in Alternating Hemiplegia of Childhood (NCT06248645) | Assistance Publique - Hôpitaux de Paris | 2024-09-16 |
| Dapagliflozin in Living-Donor Kidney Transplant Recipients (NCT07555106) | University of Guadalajara | 2024-09-15 |
| Effectivity of Protein Purified Derivative Treatment for Anogenital Warts in HIV Patient (NCT06587542) | Universitas Padjadjaran | 2024-09-15 |
| Bronchoscopic Cryoablation Combined With Chemo-Immunotherapy in NSCLC With Central Airway Obstruction (NCT06604351) | Hunan Province Tumor Hospital | 2024-09-15 |
| Human Placenta Mesenchymal Stem Cells Derived Exosomes Injection for Treatment of Complex Anal Fistula (NCT06568653) | Tehran University of Medical Sciences | 2024-09-15 |
| Sugammadex Dose Finding Under Two Years Old (NCT06575036) | Sang-Hwan Ji | 2024-09-15 |
| Efficacy and Tolerance of Solriamfetol in Patients Affected with Idiopathic Hypersomnia. (NCT06590662) | University Hospital, Montpellier | 2024-09-15 |
| PRP Spinoplasty for Chronic Low Back Pain With Multiple Pathologies: A Quasi-Experimental Study (NCT07268885) | Allmed Medical Center | 2024-09-15 |
| Comparison of Two Antibiotic Regimens for the Treatment of Early Airways Infection With PA in Adults With Bronchiectasis (NCT06368804) | Centre Hospitalier Intercommunal Creteil | 2024-09-15 |
| The Efficacy of Quadruple Therapy Containing Sodium Bicarbonate as the Primary Treatment for Helicobacter Pylori Infection (NCT06591494) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2024-09-15 |
| Tislelizumab Combined With Capecitabine for Nasopharyngeal Carcinoma With Residual EBV DNA After Radiotherapy (NCT07067268) | Fudan University | 2024-09-14 |
| A Clinical Study to Evaluate the Safety and Efficacy of JHM03 in Adult Patients With Upper Limb Spasticity (NCT06584240) | JHM BioPharma (Tonghua) Co. , Ltd. | 2024-09-14 |
| SAL-0951 in the Treatment of Chemotherapy-induced Anemia in Patients With Non-myeloid Malignancies (NCT06737081) | Shenzhen Salubris Pharmaceuticals Co., Ltd. | 2024-09-14 |
| A Clinical Trial of TQC3721 Suspension for Inhalation in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (NCT06527144) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2024-09-14 |
| A Clinical Study on Recombinant Botulinum Toxin Type A (YY001) for Injection in The Treatment of Upper Limb Spasticity in Adults (NCT06783114) | Chongqing Claruvis Pharmaceutical Co., Ltd. | 2024-09-14 |
| Comparing Cytarabine + Daunorubicin Therapy Versus Cytarabine + Daunorubicin + Venetoclax Versus Venetoclax + Azacitidine in Younger Patients With Intermediate Risk AML (A MyeloMATCH Treatment Trial) (NCT05554393) | National Cancer Institute (NCI) | 2024-09-13 |
| Immune Checkpoint Inhibitors for Organ Preservation in Non-metastatic dMMR/MSI-H Gastric or Colon Cancers (NCT06580574) | Peking University | 2024-09-13 |
| Induction Therapy of PTX+BV Followed by Atezolizumab+Nab-PTX for PD-L1+ TNBC (NCT06793553) | Japan Breast Cancer Research Group | 2024-09-13 |
| A Trial of Targeted Therapies for Patients With Slow-Flow or Fast-Flow Vascular Malformations (NCT05983159) | Murdoch Childrens Research Institute | 2024-09-13 |
| Self-acupuncture for Migraines Feasibility Study (NCT06716944) | University of West London | 2024-09-13 |
| A Study to Investigate LP-118, Ponatinib, Vincristine and Dexamethasone in Relapsed/Refractory Acute Lymphoblastic Leukemia (ALL) or Lymphoblastic Lymphoma (LBL) (NCT06207123) | University of Chicago | 2024-09-13 |
| A Phase 2 Clinical Trial Evaluating the Efficacy and Safety of HSK21542 in Patients for Postoperative Pain Treatment in Orthopedic Surgery (NCT07442877) | Haisco Pharmaceutical Group Co., Ltd. | 2024-09-13 |
| A Study of CM310 in Subjects With Moderate to Severe Chronic Obstructive Pulmonary Disease (NCT06547333) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2024-09-13 |
| Testing the Use of Fulvestrant and Binimetinib Targeted Treatment for NF1 Mutation in Hormone Receptor-Positive Metastatic Breast Cancer (A ComboMATCH Treatment Trial) (NCT05554354) | National Cancer Institute (NCI) | 2024-09-13 |
| Using Circulating Tumor DNA to Personalize Duration of Consolidation Durvalumab (NCT05757843) | Indiana University | 2024-09-13 |
| Topical 10% Povidone-Iodine in Preventing White Spots (NCT06616207) | University of Washington | 2024-09-13 |
| A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy (NCT06388707) | NaviFUS Corporation | 2024-09-13 |
| Sacituzumab govitEcan in THYroid Cancers (NCT06235216) | Grupo Espanol de Tumores Neuroendocrinos | 2024-09-13 |
| CMV Immunity Monitoring in Lung Transplant Recipients (NCT05708755) | NYU Langone Health | 2024-09-13 |
| HER2 Targeted Molecular Imaging in mBC and Other Metastatic Solid Carcinomas Using 68Ga-ABS011 (NCT06369831) | Abscint NV/SA | 2024-09-12 |
| Intraperitoneal Immune Checkpoint Inhibitors and Zoledronic Acids for Gastric Cancer Malignant Ascites (NCT06759064) | Qilu Hospital of Shandong University | 2024-09-12 |
| Placebo-Controlled Trial of Urolithin A Supplementation in Men With Prostate Cancer Undergoing Radical Prostatectomy, URO-PRO Trial (NCT06022822) | National Cancer Institute (NCI) | 2024-09-12 |
| Expanding Liver Transplant Immunosuppression Minimization Via Everolimus (NCT06280950) | National Institute of Allergy and Infectious Diseases (NIAID) | 2024-09-12 |
| Efficacy and Safety of Oral Controlled-Ileocolonic-Release Nicotinamide (CICR-NAM) in Patients With Mild to Moderately Active Ulcerative Colitis (NCT06488625) | University Hospital Schleswig-Holstein | 2024-09-12 |
| Effectiveness and Biological Mechanism of Direct Ischemic Post-conditioning for Acute Stroke Patients Due to Large Vessel Occlusion (NCT06545734) | Tianjin Huanhu Hospital | 2024-09-12 |
| Neoadjuvant Immunochemotherapy in PD-L1-negative LACC (NCT06288360) | Tongji Hospital | 2024-09-12 |
| Pilot Study of the α Prototype NIMBLE System: Feasibility, Safety, and Initial Performance in Non-Invasive Detection of Coronary In-Stent Restenosis (NCT06968858) | Nimble Diagnostics S.L. | 2024-09-12 |
| Ischemic Postconditioning in Acute Stroke Patients Receiving Endovascular Thrombectomy (NCT06967025) | Tianjin Huanhu Hospital | 2024-09-12 |
| First-line Carboplatin and Paclitaxel in Combination With Pembrolizumab, Followed by Maintenance Pembrolizumab With or Without Nesuparib, in Patients With Newly Diagnosed Advanced or Recurrent MMR-proficient (pMMR) Endometrial Cancer (NCT06502743) | Yonsei University | 2024-09-12 |
| Acute Myeloid Leukemia Treated With With NETrin Abs in Combination With [AZACITIDINE + VENETOCLAX] (NCT06150040) | Centre Leon Berard | 2024-09-11 |
| A Study to Investigate the Safety and Effectiveness of a Coagulation Factor IX Gene Insertion Therapy (REGV131-LNP1265) in Pediatric, Adolescent and Adult Participants With Hemophilia B (NCT06379789) | Regeneron Pharmaceuticals | 2024-09-11 |
| Open Label, Dose Escalation, Repeat Dose Study Evaluating YCT-529 in Healthy Males (NCT06542237) | YourChoice Therapeutics, Inc. | 2024-09-11 |
| SBRT Followed by Chemoimmunotherapy of Toripalimab Plus Docetaxel and Cisplatin for Larynx Preservation in Patients with Locally Regionally Advanced Squamous Cell Carcinoma of the Larynx and Hypopharynx (NCT06611137) | Sun Yat-sen University | 2024-09-11 |
| A Study of DC05F01 in Chinese Patients with Recurrent/Refractory Ovarian Cancer and Other Advanced Solid Tumors (NCT06873555) | Heronova Pharmaceuticals | 2024-09-11 |
| A Study of Alpelisib and Fulvestrant to Treat Endometrial Cancer (NCT05154487) | GOG Foundation | 2024-09-11 |
| Promoting Upright Mobility in Infants With Cerebral Palsy Using a Robotic Unweighting System (NCT06593886) | National Institutes of Health Clinical Center (CC) | 2024-09-11 |
| A Phase 2 Study of INCB57643 (BET Inhibitor) in Combination With Ruxolitinib in JAK Inhibitor-naïve Patients With Myelofibrosis (NCT06619522) | M.D. Anderson Cancer Center | 2024-09-11 |
| A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis (NCT06559150) | Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA | 2024-09-11 |
| Ketamine for Methamphetamine Use Disorder (NCT06496750) | University of Texas Southwestern Medical Center | 2024-09-11 |
| Early Application of Memantine and Pioglitazone to Protect Cognitive Function After Radiotherapy (NCT06594172) | Affiliated Cancer Hospital & Institute of Guangzhou Medical University | 2024-09-10 |