| Safety and Preliminary Effectiveness of BNT317, an Investigational Therapy for Advanced Solid Tumors (NCT06750185) | BioNTech SE | 2025-01-13 |
| DMID 23-0015; Lassa Fever CVD 1000 (NCT06546709) | Wilbur Chen, MD, MS | 2025-01-13 |
| The Effect of Food on the Pharmacokinetics of BN104 Tablets (NCT06724549) | BioNova Pharmaceuticals (Shanghai) LTD. | 2025-01-12 |
| Bioequivalence (BE) Study Between YHP2205 and YHR2401 in Healthy Volunteers (NCT06775522) | Yuhan Corporation | 2025-01-11 |
| A Safety and Tolerability Study of BPR-30221616 Injection in Healthy Subjects (NCT06760455) | Chengdu Brilliant Pharmaceutical Co., Ltd. | 2025-01-10 |
| Irinotecan Liposomes Combined with Epirubicin in Recurrent Non-muscle Invasive Bladder Urothelium Carcinoma After Anthracyclines Treatment (NCT06766266) | First Affiliated Hospital of Chongqing Medical University | 2025-01-10 |
| Aging Resilience Through Microbiota Optimization and Regulation (NCT06649981) | Gonzalo Jorquera, PhD | 2025-01-10 |
| An Investigational Study of BGB-58067 As a Single Agent and in Combination With Anticancer Agents in Participants With Advanced Solid Tumors (NCT06589596) | BeOne Medicines | 2025-01-10 |
| Safety and Efficacy of R-CMOP Versus R-CHOP in the Initial Treatment of DLBCL (NCT06760039) | Sun Yat-sen University | 2025-01-10 |
| Low-dose Radiotherapy Combined With Concurrent Chemotherapy, Toripalimab and Tifcemalimab in the Treatment of ES-SCLC (NCT06732258) | Sichuan University | 2025-01-10 |
| IBI3001 in Participants With Unresectable, Locally Advanced or Metastatic Solid Tumors (NCT06349408) | Innovent Biologics (Suzhou) Co. Ltd. | 2025-01-10 |
| Study of d-MAPPS™ Ophthalmic Solution, Safety, Tolerability, and Efficacy in the Treatment of Chronic Ocular Graft-Versus-Host Disease (oGVHD) (NCT06852768) | Regenerative Ocular Immunobiologics LLC | 2025-01-10 |
| A Study Evaluating the Pharmacokinetics of Three QRL-101 Formulations in Healthy Participants (NCT06877624) | QurAlis Corporation | 2025-01-10 |
| Clinical Trial of Autologous CD19 CAR-T Cells (CNCT19) Therapy for Advanced Hepatocellular Carcinoma (NCT06676982) | Zhejiang University | 2025-01-10 |
| AAV Gene Therapy Clinical Study in Adult Classic PKU (PHEdom) (NCT06332807) | NGGT INC. | 2025-01-10 |
| Iadademstat With Hypomethylating Agent in Patients With Myelodysplastic Syndrome (NCT06502145) | Medical College of Wisconsin | 2025-01-10 |
| A Study of BH-30643 in Subjects With Locally Advanced or Metastatic NSCLC Harboring EGFR and/or HER2 Mutations (NCT06706076) | BlossomHill Therapeutics | 2025-01-09 |
| Comparative Study Between Ultrasound-Guided IPACK Block (Interspace Between the Popliteal Artery and the Posterior Capsule of the Knee) with Adductor Canal Block Versus Adductor Canal Block Alone for Postoperative Pain Management in Total Knee Arthroplasty (NCT06783712) | Ain Shams University | 2025-01-09 |
| This is Comparative Study in Normal Healthy Subjects to Evaluate Pharmacokinetics, Safety, Tolerability of Bmab 1200 -Autoinjector (AI) After Single Subcutaneous Injection (45 mg) in Comparison With Bmab 1200 -Prefilled Syringe (PFS). (NCT06738277) | Biocon Biologics UK Ltd | 2025-01-09 |
| A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015 and Co-administration of BR1015-3 and BR1015-2 Under Fed Conditions (NCT06744439) | Boryung Pharmaceutical Co., Ltd | 2025-01-09 |
| A Multi-part Study of ALG-000184 to Evaluate Safety, Tolerability, Pharmacokinetics and Drug-drug Interaction Potential After Single and Multiple Doses in Healthy Volunteers (NCT06672900) | Aligos Therapeutics | 2025-01-09 |
| The Seven Trial: Exploiting the Unfolded Protein Response (NCT06076837) | HonorHealth Research Institute | 2025-01-09 |
| Study to Evaluate the Safety, Tolerability, and Efficacy of SRP-9004 Administered by Systemic Infusion in Limb Girdle Muscular Dystrophy Type 2D/R3 Participants in the United States (NCT06747273) | Sarepta Therapeutics, Inc. | 2025-01-09 |
| Bioequivalence Study to Compare Selexipag 400mcg Film Coated Tablets (400 mcg Selexipag) Versus Uptravi® 400mcg Film Coated Tablets (400 mcg Selexipag) (NCT06932198) | Humanis Saglık Anonim Sirketi | 2025-01-09 |
| A Study of SHR-4375 in Subjects With Solid Tumors (NCT06764628) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2025-01-09 |
| Buffered Lidocaine for Reducing Pain in Patients Undergoing Prostate Biopsy, BURN Trial (NCT06661902) | University of Washington | 2025-01-09 |
| Dose Escalation Study of EG110A, Administered by Intradetrusor Injections to Adults With Neurogenic Detrusor Overactivity-related Incontinence Following Spinal Cord Injury Who Regularly Perform Clean Intermittent Catheterization (NCT06596291) | Cyllene Therapeutics | 2025-01-08 |
| DB107-RRV, DB107-FC, and Radiation Therapy With or Without Temozolomide (TMZ) for High Grade Glioma (NCT06504381) | University of California, San Francisco | 2025-01-08 |
| A Study to Evaluate Effect of Verapamil and Food of Sevasemten in Healthy Volunteers (NCT06916897) | Edgewise Therapeutics, Inc. | 2025-01-08 |
| A Phase 2 Study of HX301 in Patients with High-grade Giloma (NCT06703255) | Hangzhou Hanx Biopharmaceuticals, Ltd. | 2025-01-08 |
| Study to Investigate Intravenous Blinatumomab in Japanese Adult Participants With Newly Diagnosed Philadelphia-negative B-precursor Acute Lymphoblastic Leukemia (B-ALL) (NCT06649006) | Amgen | 2025-01-08 |
| A Clinical Study to Explore the Safety and Efficacy of CT0991 in Relapsed/Refractory Acute Myeloid Leukemia (NCT06709131) | He Huang | 2025-01-08 |
| A Study of Evofosfamide in Combination with Zalifrelimab and Balstilimab (NCT06782555) | ImmunoGenesis | 2025-01-08 |
| Study of SHR-A1811 Combined With Pyrotinib and Bevacizumab in Advanced Breast Cancer With Brain Metastasis (NCT06718933) | Fudan University | 2025-01-08 |
| A Study to Investigate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy With GenSci122 in Participants With Advanced Solid Tumors (NCT06772415) | Changchun GeneScience Pharmaceutical Co., Ltd. | 2025-01-08 |
| A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of CD-001 in Patients With Advanced Solid Tumors (NCT06801470) | CD (Suzhou) Biopharma Co., Ltd. | 2025-01-08 |
| Effect of Psiguavin for Obesity Treatment (PSIGUAVIN) (NCT06512818) | Universidad Católica San Antonio de Murcia | 2025-01-08 |
| Study of IBI3005 in Subjects With Unresectable, Locally Advanced or Metastatic Solid Tumors (NCT06418061) | Innovent Biologics (Suzhou) Co. Ltd. | 2025-01-08 |
| A Study Investigating [14C]-Labeled RO7269162 in Healthy Male Participants (NCT06733298) | Hoffmann-La Roche | 2025-01-08 |
| CHemotherapy and Stool Transplant in PDAC (CHASe-PDAC) (NCT06393400) | John Lenehan | 2025-01-08 |
| A Study of Ruxolitinib in Combination With Ulixertinib in People With Myelofibrosis (NCT06773195) | Memorial Sloan Kettering Cancer Center | 2025-01-07 |
| A Study to Evaluate Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Dose of LEO 158968 (NCT06444867) | LEO Pharma | 2025-01-07 |
| Safety and PK of Ceftibuten-ledaborbactam Etzadroxil Fixed-dose Combination (NCT06733675) | Basilea Pharmaceutica | 2025-01-07 |
| A Phase I/II Trial to Evaluate Oral HP568 Tablets in Patients with ER+/HER2 Advanced Breast Cancer (NCT06757335) | Hinova Pharmaceuticals Inc. | 2025-01-07 |
| A Clinical Trial to Assess COM503 in Participants With Advanced Solid Malignancies (NCT06759649) | Compugen Ltd | 2025-01-07 |
| Drug-drug Interaction Study of Bemnifosbuvir/Ruzasvir (BEM/RZR) and Buprenorphine/Naloxone or Methadone (NCT07314346) | Atea Pharmaceuticals, Inc. | 2025-01-07 |
| A Phase 1 Study of LNCB74 in Advanced Solid Tumors (NCT06774963) | NextCure, Inc. | 2025-01-07 |
| A Study of STAR-0310 in Healthy Adult Participants (NCT06782477) | Astria Therapeutics, Inc. | 2025-01-07 |
| A First in Human Trial to Assess the Safety and Immunogenicity of LTB-SA7 Vaccine Against Staphylococcus Aureus. (NCT06719219) | LimmaTech Biologics AG | 2025-01-07 |
| UC-MSC Cell Therapy Study for Systemic Lupus Erythematosus (SLE) Patients (NCT06737380) | LiveKidney.Bio | 2025-01-07 |
| A Phase Ⅰ Clinical Study of GEN-725 Tablets in Patients With Advanced Solid Tumors (NCT07229898) | Henan Genuine Biotech Co., Ltd. | 2025-01-07 |
| Safety, Tolerability, Pharmacokinetics And Pharmacodynamics of SUVN-I6107 In Healthy Participants (NCT06705088) | Suven Life Sciences Limited | 2025-01-07 |
| Effect of Magnesium Sulfate on Hemodynamics on Laparoscopic Cholecystectomy Patients (NCT07079514) | Ziauddin University | 2025-01-06 |
| qEEG Brain Signature of Depression & Neuromodulation-induced Recovery (NCT06719427) | Sunnybrook Health Sciences Centre | 2025-01-06 |
| Hypophysectomy by Stereotactic Radiosurgery for Cancer-Related Pain (NCT06287515) | M.D. Anderson Cancer Center | 2025-01-06 |
| A Safety, Tolerability, Pharmacokinetic Study of SHR-6934 Injection in Healthy Subjects (NCT06700083) | Beijing Suncadia Pharmaceuticals Co., Ltd | 2025-01-06 |
| A Study to Learn More About the Study Medicine PF-07275315 in Healthy Chinese Adult Participants (NCT06675188) | Pfizer | 2025-01-06 |
| A Phase 1b Study of QX1206 in T2DM Patients With NAFLD (NCT06694935) | 1Globe Health Institute | 2025-01-06 |
| To Evaluate the Safety/Tolerability and Pharmacokinetic Characteristics in Healthy Volunteers (NCT06703710) | JW Pharmaceutical | 2025-01-06 |
| Photodynamic Therapy of Primary Localized Prostate Cancer With the SpectraCure P18 System (NCT06807359) | SpectraCure AB | 2025-01-06 |
| A Study on the Safety and Immunogenicity of Hexavalent Influenza mRNA Vaccine in Adult Participants 50 Years of Age and Older (NCT06744205) | Sanofi Pasteur, a Sanofi Company | 2025-01-06 |
| Quantitative Fluorescence Molecular Imaging of Ustekinumab-800CW to Elucidate the Drug Distribution Throughout Inflamed Tissue in Crohn's Disease and Psoriasis. (NCT05725876) | University Medical Center Groningen | 2025-01-06 |
| A Study to Learn About Bivalent COVID-19 RNA Vaccine Candidate(s) in Healthy Infants and Children (NCT05630352) | BioNTech SE | 2025-01-06 |
| A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015 and Co-administration of BR1015-1 and BR1015-2 in Healthy Volunteers Fed Conditions (NCT06744062) | Boryung Pharmaceutical Co., Ltd | 2025-01-05 |
| A Study to Investigate the Interaction Between TMP-301 and Cocaine. (NCT06648668) | Tempero Bio, Inc. | 2025-01-04 |
| Subtenon Autologous Platelet-Rich Plasma in Inherited and Degenerative Retinal Diseases (NCT07341919) | Rubens Camargo Siqueira | 2025-01-04 |
| A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015 and Co-administration of BR1015-3 and BR1015-2 Under Fasting Conditions (NCT06744426) | Boryung Pharmaceutical Co., Ltd | 2025-01-04 |
| Safety and Pharmacokinetics of Y-4 Tablets in Healthy Subjects (NCT06935682) | Beijing Tiantan Hospital | 2025-01-04 |
| A Dose-escalation Study Followed by a Dose Optimal Study to Evaluate the Safety and Efficacy of CID-103 in Adults With Chronic Immune Thrombocytopenia (NCT07017725) | CASI pharmaceuticals, Inc. | 2025-01-03 |
| Cryoablation and Arterial Infusion of SD-101 in Combination With Durvalumab and Tremelimumab (NCT06710223) | University of California, San Diego | 2025-01-03 |
| Dapagliflozin on Outcomes of Rhythm Control Strategy (Pharmacological ± Interventional) in Patient with Atrial Fibrillation (NCT06759909) | Assiut University | 2025-01-03 |
| A Study to Evaluate the Pharmacokinetics and the Safety After Administration of BR1015 and Co-administration of BR1015-1 and BR1015-2 Under Fasting Conditions (NCT06744127) | Boryung Pharmaceutical Co., Ltd | 2025-01-03 |
| Topical 0.5% Timolol Solution for Healing Lower Extremity Wounds (NCT06941467) | Icahn School of Medicine at Mount Sinai | 2025-01-03 |
| Autologous CD19 Car T-Cell Therapy For Severe Refractory Systemic Lupus Erythematosus (SLE) (NCT06710717) | National University of Malaysia | 2025-01-03 |
| GRAViceptive NEGlect Treatment in Acute Stroke Using Targeted Cranial ELECTrotherapy (NCT06747676) | University of Sao Paulo | 2025-01-03 |
| Subcutaneously Administered MD-18 for the Treatment of Obesity and Diabetes (NCT06739707) | Cohen Global, Ltd. | 2025-01-02 |
| Validation of Nanosensor Oxygen Measurement (NCT06819683) | Children's Hospital of Philadelphia | 2025-01-02 |
| A Study of BL-M08D1 in Patients With Relapsed or Refractory Lymphoid Malignancies (NCT06718634) | Sichuan Baili Pharmaceutical Co., Ltd. | 2025-01-02 |
| CLIC-2201 for the Treatment of Relapsed/Refractory B Cell Malignancies (NCT06208735) | British Columbia Cancer Agency | 2025-01-02 |
| Trial LEP-F1 + GLA-SE in Healthy Adult in Areas Endemic for Leprosy (NCT06627257) | The Immunobiological Technology Institute (Bio-Manguinhos) / Oswaldo Cruz Foundation (Fiocruz) | 2025-01-02 |
| Clinical Study of 68Ga-LNC1007 Injection PET/CT (NCT06463782) | Yantai LNC Biotechnology Singapore PTE. LTD. | 2025-01-02 |
| A Single-center, Open, Randomized, Single-dose, Cross-over Bioequivalence Study to Evaluate the Effects of the Test Formulation Abalparatide Injection and the Reference Formulation Abalparatide Injection (Tymlos®) in Healthy Adult Subjects (NCT06753864) | The Affiliated Hospital of Qingdao University | 2025-01-02 |
| A Study to Find Out How Litifilimab is Processed in the Body in Healthy Participants When Given Under the Skin in 3 Different Ways (NCT06741657) | Biogen | 2025-01-02 |
| A Study of Lithium and Enlicitide in Healthy Adult Participants (MK-0616-034) (NCT06719544) | Merck Sharp & Dohme LLC | 2025-01-02 |
| ABX-002 Bioequivalence and Effect of Food Study in Healthy Adult Participants (NCT07652697) | Autobahn Therapeutics, Inc. | 2025-01-02 |
| A Dose-Image Optimization Trial Evaluating Mannitol and Voluven as Adjuncts for Indocyanine Green (NCT06768268) | National Taiwan University Hospital | 2025-01-01 |
| Study Safety and Efficacy of Deep Brain Stimulation (DBS) and Cervical Deep Lymphoid-venous Anastomosis (LVA) in Alzheimer's Disease (NCT07094438) | Chinese PLA General Hospital | 2025-01-01 |
| Clinical and Radiographic Evaluation of Allogenic Dentin Grafts for Alveolar Ridge Preservation (NCT06827665) | Jordan University Hospital | 2025-01-01 |
| Herbal Evaluation Of Artemisia Annua For Small Intestinal Bacterial Overgrowth (NCT06721884) | National University of Natural Medicine | 2025-01-01 |
| ACHIEVE2 - Safety and Preliminary Efficacy of Intravenous TCB008 in Patients With Relapse or Refractory Acute Myeloid Leukemia (AML) or Myelodysplastic Syndrome (MDS)/AML (NCT06463327) | TC Biopharm | 2025-01-01 |
| CBD Delivery with the A-Synaptic GT4 Transdermal Delivery System in with Dravet Syndrome And/or Lennox-Gastaut Syndrome (NCT06738732) | Alexander Rotenberg | 2025-01-01 |
| Medical Herbs Inhibit Inflammation Directing T Cells to Kill the COVID-19 Virus (COVID) (NCT04790240) | All Natural Medicine Clinic, LLC | 2025-01-01 |
| RT for Adenocarcinoma/Adenosquamous Carcinoma (NCT07153952) | Peking Union Medical College Hospital | 2025-01-01 |
| Phase 1b/2a in SLE With Budoputug (NCT06570434) | Tenet Medicines | 2025-01-01 |
| Tolerance Study of Allogeneic of Adipose Tissue Derived Mesenchymal Stroma/Stem Cells (AdMSC) Transplantation in Patients With Critical Limb Ischemia. (NCT06795620) | University Hospital, Toulouse | 2025-01-01 |
| Treating Claudin18.2-positive Advanced Solid Tumors with XKDCT225(Targeting Claudin18.2-CAR-T) (NCT06782425) | Shenzhen Celconta Life Science Co., Ltd. | 2025-01-01 |
| Effort and Antidepressant Study Test (NCT06696482) | University of Oxford | 2025-01-01 |
| Proprioceptive Neuromuscular Facilitation vs Conventional Therapy With Ultrasound-Guided Corticosteroid Injections for Subacromial Bursitis (NCT07508969) | University of Catanzaro | 2025-01-01 |
| A Study to Evaluate the Safety, Tolerability and Efficacy in Patients With Burn(s) (NCT06440239) | Primoris Therapeutics | 2025-01-01 |
| COmmencing Menopausal HOrmone Replacement Therapy and the Effect on Metabolic-dysfunction Associated Steatotic Liver Disease: a Pilot Mechanistic Study (NCT06704516) | University of Oxford | 2025-01-01 |