| A Study to Test How Well Multiple Doses of BI 3810477 Are Tolerated by Healthy Adults (NCT06984926) | Boehringer Ingelheim | 2025-06-06 |
| A Phase Ib Study of JMKX001899 in Combination With Other Therapies in Advanced NSCLC Harboring KRAS G12C Mutation (NCT06946927) | Jemincare | 2025-06-06 |
| Drug Interaction Study of ZYN002 Transdermal Gel and Probe Substrates (NCT06930872) | Harmony Biosciences Management, Inc. | 2025-06-06 |
| Acute Effects of THC in Older Adult (NCT06948136) | Yale University | 2025-06-06 |
| A Study to Evaluate the Relative Bioavailability of Povetacicept Formulations and Bioequivalence of Povetacicept Presentations (NCT07010406) | Vertex Pharmaceuticals Incorporated | 2025-06-06 |
| A Study to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Immunogenicity of AZD1613 in Healthy Participants. (NCT06995820) | AstraZeneca | 2025-06-06 |
| First-in-Human Study of ADCE-D01 in Soft Tissue Sarcoma (NCT06797999) | Adcendo ApS | 2025-06-05 |
| Investigation of Pharmacokinetics and Safety of HRS-7535 in Subjects With Hepatic Impairment and Normal Hepatic Function (NCT06961643) | Shandong Suncadia Medicine Co., Ltd. | 2025-06-05 |
| Intrathecal Azacitidine and Nivolumab in Patients With Recurrent High-grade Glioma (NCT06896110) | Andrew P. Groves | 2025-06-05 |
| Study of AUBE00 in Patients With Solid Tumors (NCT07030959) | Chugai Pharmaceutical | 2025-06-05 |
| A Study of ERAS-0015 in Patients With Advanced or Metastatic Solid Tumors (NCT06983743) | Erasca, Inc. | 2025-06-05 |
| An Open-label Study in Healthy Adults to Evaluate the Relative Bioequivalence of a Single-dose Administration of Sonelokimab Either by a Prefilled Syringe or an Autoinjector (NCT06994936) | MoonLake Immunotherapeutics AG | 2025-06-05 |
| A First-in-Human Study of ALK-N001 for Injection in Patients With Advanced Solid Tumors (NCT07529535) | Zhejiang Anglikang Pharmaceutical Co., Ltd. | 2025-06-05 |
| First-in-Human Single and Multiple Dose of KLA578-1 for Injection (NCT07143318) | Hunan Kelun Pharmaceutical Co., Ltd. | 2025-06-05 |
| A Phase I/II Study to Evaluate the Safety and Immunogenicity of GC3111B in Healthy Adults (NCT06997627) | GC Biopharma Corp | 2025-06-05 |
| Application of KRAS Vaccine in the Treatment of KRAS-mutated Malignancies (NCT07004244) | Sichuan University | 2025-06-05 |
| A Study to Investigate the Effect of AZD6234, AZD9550, and a Combination of AZD9550 and AZD6234 on Pharmacokinetics of Combined Oral Contraceptive Ethinyl Estradiol/Levonorgestrel in Healthy Female Participants Living With Overweight or Obesity (NCT07013643) | AstraZeneca | 2025-06-04 |
| Testing the Feasibility and Acceptability of Social Media and Digital Therapeutics to Decrease Vaping Behaviors (NCT05994209) | Washington University School of Medicine | 2025-06-04 |
| AVENTINE-1: Study of AVZO-1418 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (AVZO-1418-1001) (NCT07038343) | Avenzo Therapeutics, Inc. | 2025-06-04 |
| Focused Ultrasound Blood-Brain Barrier Disruption for the Treatment of High-Grade Glioma in Patients Undergoing Standard Chemotherapy (NCT07179328) | Sunnybrook Health Sciences Centre | 2025-06-04 |
| An Active Comparator Safety Study Evaluating the Combination of APG777 + APG990 in Moderate-to-Severe Atopic Dermatitis (NCT07027527) | Apogee Therapeutics, Inc. | 2025-06-04 |
| Study of ESG406 in Adults With Solid Tumors (NCT06979674) | Shanghai Escugen Biotechnology Co., Ltd | 2025-06-04 |
| A Study to Understand How the Study Medicine (PF-07976016) is Processed and Eliminated in Healthy Men (NCT07015918) | Pfizer | 2025-06-04 |
| A Study of GNC-038 Tetra-specific Antibody Injection in Patients With Systemic Lupus Erythematosus (NCT06857214) | Sichuan Baili Pharmaceutical Co., Ltd. | 2025-06-04 |
| Phase I PK Comparison of HLX05 vs. Erbitux® in Healthy Chinese Males: Safety, Immunogenicity, and Pharmacokinetics (NCT06980454) | Shanghai Henlius Biotech | 2025-06-04 |
| A Study Investigating the Safety of RO7795081 and the Effect of RO7795081 on How the Body Processes Pitavastatin and Rosuvastatin in Otherwise Healthy Overweight or Obese Adult Participants (NCT06982131) | Hoffmann-La Roche | 2025-06-04 |
| The Role of Vitamin K on Knee Osteoarthritis Outcomes (NCT06385275) | Boston University | 2025-06-03 |
| EF-M2 (Immutalon) Multiple Ascending Dose Study in Moderate-to-Severe Rheumatoid Arthritis (NCT07349420) | S.LAB (SOLOWAYS) | 2025-06-03 |
| A Study to Evaluate Single-dose of HB0043 in Healthy Adult Participants (NCT06999083) | Shanghai Huaota Biopharmaceutical Co., Ltd. | 2025-06-03 |
| XL092 and Cemiplimab in BRAF WT Thyroid Cancer (NCT06902376) | UNC Lineberger Comprehensive Cancer Center | 2025-06-03 |
| A Study of Oral Tetrahydrouridine-Decitabine in Relapsed or Refractory Myelodysplastic Syndromes (MDS) (NCT07006025) | Treebough Therapies | 2025-06-03 |
| Phase 1 Study to Evaluate the Safety, Tolerability, PK, and PD of TVB-3567 in Healthy Participants With or Without Acne (NCT06989840) | Sagimet Biosciences Inc. | 2025-06-03 |
| A Study of DR-0202 in Patients With Locally Advanced or Metastatic, Relapsed or Refractory Carcinomas (NCT06999187) | Dren Bio | 2025-06-03 |
| A First-in-human, Clinical Trial Assessing the Safety of ES2B-C001-S01 With or Without [Adjuvant] in Patients With HER2-expressing Metastatic Breast Cancer. (NCT06746688) | ExpreS2ion Biotechnologies | 2025-06-03 |
| A Study to Assess NEU-627 in Healthy Participants (NCT06900751) | Neuron23 Inc. | 2025-06-02 |
| A Study to Evaluate the Effect of Retatrutide on Insulin Secretion and Insulin Sensitivity in Adult Participants With Type 2 Diabetes Mellitus (NCT06982859) | Eli Lilly and Company | 2025-06-02 |
| DFT383 in Pediatric Participants With Nephropathic Cystinosis (NCT06910813) | Novartis Pharmaceuticals | 2025-06-02 |
| IBI343 Combined With Sintilimab Plus Chemotherapy in Gastric Cancer (NCT07025889) | Ruijin Hospital | 2025-06-02 |
| The Combination of Pharmacotherapy and Cognitive Behavioral Psychotherapy Under the Recovery Perspective. (NCT06993662) | Rakitzi, Stavroula | 2025-06-02 |
| Tumor Infiltrating Lymphocyte Therapy for Pediatric High Risk Solid Tumors (NCT06047977) | H. Lee Moffitt Cancer Center and Research Institute | 2025-06-02 |
| Copanlisib and Avelumab as a Maintenance Therapy for Advanced Bladder Cancer (NCT05687721) | VA Office of Research and Development | 2025-06-02 |
| PET [89Zr]DFO-starPEG in Solid Tumors (NCT06894745) | Robert Flavell, MD, PhD | 2025-06-02 |
| A Study to Assess the Tolerability and Safety of Subcutaneously (SC) Administered Immunoglobulin G (IgG) With Varying Injection Conditions (NCT07025577) | Genentech, Inc. | 2025-06-02 |
| A Phase IB 2 Dose Trial of IRS-1 HSV C134 (IND 17296) Administered Intratumorally in Patients With Recurrent Malignant Glioma (NCT06614855) | James Markert, MD | 2025-06-02 |
| Neuroinflammation and Age-associated Brain Pathology: Two Potential Mechanisms of Cognitive Impairment in Ovarian Cancer (NCT04542603) | University of Alabama at Birmingham | 2025-06-01 |
| TCR1020-CD8 T Cells in KRAS-mutated Cancers (NCT06707896) | University of Pennsylvania | 2025-06-01 |
| SHR - A1811 Injection in the Treatment of Platinum-sensitive Recurrent Ovarian Cancer (NCT06990516) | Tongji Hospital | 2025-06-01 |
| CD5 CAR T-Cell Therapy for r/r T-cell Lymphomas (NCT07022964) | Beijing GoBroad Hospital | 2025-06-01 |
| Comparison of 3Mixtatin Pulpotomy and Metapex Pulpectomy in Primary Molars With Irreversible Pulpitis (NCT06925490) | Cairo University | 2025-06-01 |
| CaspoNEB: Efficacy and Safety of Caspofungin Aerosols for the Curative Treatment of Pneumocystis Pneumonia (NCT06892951) | University Hospital, Tours | 2025-06-01 |
| Study to Evaluate the Safety, Tolerability, and Efficacy of PEP-TISSEEL in Subjects With Chronic Radiation Ulcer (NCT06793748) | Rion Inc. | 2025-06-01 |
| Maintenance Therapy With Selinexor and Azacitidine in TP53 Mutant AML/MDS After Transplantation (NCT07094464) | Daihong Liu | 2025-06-01 |
| Steroid Injection in Idiopathic Granulomatous Mastitis (NCT06985537) | Assiut University | 2025-06-01 |
| The Food Effect on Pharmacokinetics Study of QLC1101 in Healthy Subjects (NCT06980909) | Qilu Pharmaceutical Co., Ltd. | 2025-06-01 |
| Gegen Qinlian Tang and Probiotics for Radiation Enteritis (NCT06836960) | Jiujiang No.1 People's Hospital | 2025-06-01 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of ASC50 Tables in Healthy Participants and Participants With Plaque Psoriasis (NCT07024602) | Ascletis Pharma (China) Co., Limited | 2025-06-01 |
| A Study of Varenicline in the Treatment of Visceral Sensation (NCT06854406) | Mayo Clinic | 2025-06-01 |
| Pilot Study on a New Self Adjustable Glaucoma Drainage Device (NCT07480603) | Rheon Medical SA | 2025-06-01 |
| A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of HS-10510 in Healthy Subjects (NCT07001787) | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 2025-06-01 |
| A Randomized Controlled Trial of Oral CBD for the Treatment of Upper Extremity Musculoskeletal Pain (NCT06695195) | Brent DeGeorge | 2025-06-01 |
| A Study of SGB-3383 in Healthy Subjects (NCT06995326) | Suzhou Sanegene Bio Inc. | 2025-06-01 |
| Molecular Neuroimaging to Assess the Link Between Neuroinflammation and Cognitive Impairment in Breast Cancer (NCT04364672) | University of Alabama at Birmingham | 2025-06-01 |
| Psilocybin With Intracranial Neural Sensing (NCT06919640) | Joshua Woolley, MD, PhD | 2025-06-01 |
| Dose Escalation Study of Vinpocetine in Healthy Volunteers (NCT06635746) | Stanford University | 2025-06-01 |
| Single Ascending Dose and Multiple Ascending Dose Study of AVR-48 (NCT06847698) | AyuVis Research, Inc. | 2025-06-01 |
| ROLE OF PROPHYLACTIC TRANEXAMIC ACID IN PREVENTION OF POST-PARTUM HEMORRHAGE IN ELLSCS (NCT07002749) | Patel Hospital, Pakistan | 2025-06-01 |
| Lentiviral FIX Gene Therapy (NCT03961243) | Shenzhen Geno-Immune Medical Institute | 2025-06-01 |
| Clinical Trial of Comparing DA-5222 Single-administration and Co-administration of DA-5222-R1, DA-5222-R2 and DA-5222-R3 in Healthy Adult Subjects (NCT06993181) | Dong-A ST Co., Ltd. | 2025-06-01 |
| Ilioinguinal Nerve Block With Local Anesthetic vs. Placebo in Inguinal Hernia Repair Under Spinal Anesthesia (NCT07049835) | Makassed General Hospital | 2025-06-01 |
| Randomized Trial of Glutathione With Anti-PD-1 and Chemotherapy in Advanced NSCLC (NCT06896422) | The First Affiliated Hospital of Zhengzhou University | 2025-06-01 |
| A Phase Ib/II Study to Evaluate Multiple Combination Therapies of FWD1802 in Patients With ER+/HER2- BC (NCT07002177) | Forward Pharmaceuticals Co., Ltd. | 2025-06-01 |
| Partial Rotator Cuff Injury Combined With Stiff Shoulder (NCT07192302) | Hebei Medical University Third Hospital | 2025-06-01 |
| Bioavailability of Stiripentol After Single Oral Dose of Capsule vs Suspension in Healthy Subjects (STILIQ) (NCT07176832) | Biocodex | 2025-06-01 |
| Effect of Topical Diltiazem Plus Fusidic Acid Versus Fusidic Acid Alone on Episiotomy Healing, Pain, and Resumption of Sexual Activity: A Randomized Controlled Trial in Azadi Teaching Hospital (NCT07545187) | Alaa Nadhim Hameed | 2025-06-01 |
| A Phase Ib Study of QLS4131 in Subjects With Systemic Lupus Erythematosus (NCT07001839) | Qilu Pharmaceutical Co., Ltd. | 2025-06-01 |
| A Repeat-Dose, Open-Label, Two Arm Safety and Efficacy Study of Two Doses of VP-001 Administered Intravitreally in Participants With Confirmed PRPF31 Mutation-Associated Retinal Dystrophy, Including Participants Previously Treated With VP001 (NCT06852963) | PYC Therapeutics | 2025-06-01 |
| SCT-001 CAR T Cells Therapy for Relapsed and Refractory Ovarian Cancer (NCT06846424) | Shanghai Gynecologic Oncology Group | 2025-06-01 |
| Facilitating Neuroplastic Changes of Acute Stroke Survivors (NCT06404268) | University of Maryland, Baltimore | 2025-06-01 |
| Drug-Drug Interaction Between R1_PBK_M2301 and R2_PBK_M2301 in Healthy Adults (NCT07017335) | Pharmbio Korea Co., Ltd. | 2025-06-01 |
| Improving Sleep in a Psychiatric Hospital (NCT07010718) | The University of Texas Health Science Center, Houston | 2025-06-01 |
| CRISPR-Edited HLA Donor Kidney Transplant to Reduce Rejection Risk (NCT07053462) | AMERICAN ORGAN TRANSPLANT AND CANCER RESEARCH INSTITUTE LLC | 2025-06-01 |
| TACE Plus Ivonescimab for Unresectable Non-Metastatic HCC (NCT06990620) | Fudan University | 2025-06-01 |
| EFFICACY OF IV VERSUS ORAL IRON IN THE TREATMENT OF IRON DEFICIENCY ANEMIA DURING PREGNANCY (NCT07384663) | Dr Salaha Azam | 2025-06-01 |
| CRISPR-Edited HLA Donor Liver Transplant to Reduce Rejection (NCT07053488) | AMERICAN ORGAN TRANSPLANT AND CANCER RESEARCH INSTITUTE LLC | 2025-06-01 |
| Safety and Efficacy of an Arginine-Restricted Diet in Patients With Solid Tumors (NCT07038044) | West China Hospital | 2025-06-01 |
| Comparing Safety and Protective Efficacy of Vaccine Candidate PfSPZ-CVac and MVA ME-TRAP/ ChAd63 ME-TRAP in Adults (NCT05441410) | University Hospital Tuebingen | 2025-06-01 |
| Romiplostim N01 for Platelet Recovery After Haploidentical HSCT (NCT07321626) | First Affiliated Hospital of Zhejiang University | 2025-06-01 |
| Autologous Bone Marrow Mesenchymal Stem Cell Therapy for Ischemic Stroke (NCT06997939) | Affiliated Hospital of Nantong University | 2025-06-01 |
| A Multiple Ascending Dose Study of DT-216P2 in Patients With Friedreich's Ataxia (NCT06874010) | Design Therapeutics, Inc. | 2025-06-01 |
| A Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of QLC1101 in Combination With Other Therapies in the Treatment of Patients With Advanced Solid Tumors Harboring a KRAS G12D Mutation (NCT06949761) | Qilu Pharmaceutical Co., Ltd. | 2025-06-01 |
| Hyaluronidase Enzymes and Local Anesthesia (NCT06980363) | Fayoum University | 2025-06-01 |
| Theta-Burst Stimulation to Treat Depression (NCT07033780) | Centre for Addiction and Mental Health | 2025-06-01 |
| Study of JSKN016 Combination Therapy in Inoperable Locally Advanced or Metastatic HER2-Negative Breast Cancer (NCT06942234) | Jiangsu Alphamab Biopharmaceuticals Co., Ltd | 2025-06-01 |
| Multi-center Study on CCeLL-In Vivo's Clinical Efficacy for Intraoperative Brain Tumor Diagnosis. (NCT06867978) | VPIX Medical | 2025-06-01 |
| A Pharmacokinetic, Safety, and Tolerability Study of LUCEMYRA in the Treatment of Opioid Withdrawal Management in Adolescent Subjects (NCT06711640) | USWM, LLC (dba US WorldMeds) | 2025-06-01 |
| A Study of OL-108 in Relapsed/Refractory Autoimmune Diseases (NCT06980597) | Beijing GoBroad Hospital | 2025-06-01 |
| The Effectiveness of Herbal Creams Compared to Urea in Dry Skin Treatment (NCT07360639) | Universitas Syiah Kuala | 2025-06-01 |
| An Open-label Study of GB261 in Refractory Seropositive Systemic Lupus Erythematosus (NCT06945068) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2025-06-01 |
| Transarterial Chemoembolization (TACE) Plus Bevacizumab for Liver Metastases (NCT06311851) | Pardis Noor Medical Imaging and Cancer Center | 2025-06-01 |
| EBV-AST Cell Injection for EBV-Associated Lymphoproliferative Disorders (NCT07450391) | Daihong Liu | 2025-06-01 |