| A Study of LCAR-AIO CAR-T Cells for Treating Relapsed/Refractory Neurological Autoimmune Diseases (NCT06869278) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2025-06-17 |
| First-in-human Trial of STC-1010, an Immunotherapy, in Patients With Unresectable Locally Advanced or Metastatic Colorectal Cancer (NCT06934538) | Brenus Pharma | 2025-06-17 |
| Study of BEBT-507 Injection in Subjects With Polycythemia Vera (PV) (NCT07012109) | BeBetter Med Inc | 2025-06-17 |
| Clinical Outcomes of Early Kasai Surgery With Umbilical Cord MSCs in Biliary Atresia (NCT07011199) | Universitas Diponegoro | 2025-06-17 |
| A Clinical Trial to Evaluate the Safety, Tolerability and Clinical Efficacy of M3T01 Monotherapy and in Combination With Pembrolizumab and Other Systemic Therapies (NCT06719362) | Providence Health & Services | 2025-06-17 |
| Evaluating Informatics-assisted Immune-related Adverse Event Detection to Improve Registration Onto a Biorepository (NCT06789601) | Brigham and Women's Hospital | 2025-06-17 |
| Tolerance and Pharmacokinetic/Pharmacokinetic Study of IBI362 15mg in Patients With Moderate to Severe Obesity (NCT07000955) | Innovent Biologics (Suzhou) Co. Ltd. | 2025-06-17 |
| A Bioequivalence Study to Evaluate Pharmacokinetics and Safety of BR2022 and BR2022-1 in Patients With Deleterious or Suspected Deleterious Germline BRCA-Mutated Advanced Ovarian Cancer (NCT07069335) | Boryung Pharmaceutical Co., Ltd | 2025-06-17 |
| Impact of Daily Oral Cannabis Doses in Patients With Cancer (NCT06601218) | Shanna Babalonis, PhD | 2025-06-17 |
| Intracranial Genetically Modified Immune Cells (TGFβR2KO/IL13Rα2 CAR T-Cells) for the Treatment of Recurrent or Progressive Glioblastoma or Grade 3 or 4 IDH-Mutant Astrocytoma (NCT06815029) | City of Hope Medical Center | 2025-06-17 |
| A Clinical Study of SHR-1316 (SC) Combined With Carboplatin and Etoposide as First-line Treatment for Extensive Stage Small Cell Lung Cancer (NCT07009457) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2025-06-16 |
| Safety and Tolerability Evaluation of CEL001 Injection in Advanced Solid Tumors (NCT07259889) | Guangzhou Xiling Biotechnology Co., Ltd. | 2025-06-16 |
| An Open-label Study of CND261 in Seropositive Rheumatoid Arthritis (NCT07052032) | Candid Therapeutics | 2025-06-16 |
| Phase 1/2 Study of ABO-101 in Primary Hyperoxaluria Type 1 (redePHine) (NCT06839235) | Arbor Biotechnologies | 2025-06-16 |
| Epcoritamab for the Treatment of Relapsed or Refractory Post Transplant Lymphoproliferative Disorders (NCT06672705) | Timothy Voorhees | 2025-06-16 |
| A Study to Evaluate the Safety and Efficacy of OPB-101 in Platinum-resistant Ovarian Cancer (NCT07030907) | Outpace Bio, Inc. | 2025-06-16 |
| A Clinical Trial of SIBP-A18 Injection in the Treatment of Advanced Malignant Solid Tumor Patients (NCT06985368) | Shanghai Institute Of Biological Products | 2025-06-16 |
| RB001 Gene Therapy Study in Children With SHANK3-related Phelan-McDermid Syndrome (PMS) (NCT07014020) | Peking University First Hospital | 2025-06-16 |
| Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics And Pharmacodynamics of SIF001 in Healthy Subjects and in Epilepsy Patients (NCT07051629) | Suninflam Inc | 2025-06-16 |
| Phase I Study of HBT-708 for Patients With Advanced Solid Tumors (NCT06993870) | Shenyang Sunshine Pharmaceutical Co., LTD. | 2025-06-16 |
| Effects of CBD/CBD-A Oral Extract on Resting-state EEG and Neuropathic Pain Symptoms After SCI (NCT05630235) | University of Miami | 2025-06-16 |
| A Comparative Bioavailability Study of Tamsulosin 0.4 mg Prolonged-release Tablets Versus the Reference Drug Omnic Ocas®, Tamsulosin 0.4 mg Tablets, in Healthy Adult Male Subjects, Under Fed Conditions (NCT07091669) | Berlin-Chemie AG Menarini Group | 2025-06-16 |
| Safety of MT-401-OTS in Patients With Relapsed AML or MDS (NCT06552416) | Marker Therapeutics, Inc. | 2025-06-16 |
| Safety and Pharmacokinetics of LPX-TI641 in Atopic Dermatitis and Psoriasis (NCT06982352) | LAPIX Therapeutics Inc. | 2025-06-15 |
| A Trial of HRS-5041-103 to Evaluate the Safety, Tolerability, Pharmacokinetics and Efficacy of HRS-5041 in Subjects With Metastatic Castration-resistant Prostate Cancer (NCT06830850) | Atridia Pty Ltd. | 2025-06-15 |
| A Study to Understand the Safety of the 20vPnC Vaccine in Healthy Chinese Adults, Children, and Infant (NCT07023081) | Pfizer | 2025-06-15 |
| Prostate Cancer Vaccines (NCT07068555) | Shenzhen Geno-Immune Medical Institute | 2025-06-15 |
| Phage Therapy for Recurrent UTIs in Kidney Transplant Recipients (NCT06409819) | University of California, San Diego | 2025-06-15 |
| Comparative Pharmacokinetic, Pharmacodynamic, and Safety Study of 1 Dose of Aspirin for Injection and Oral Aspirin Tablets in Healthy Adult Subjects (NCT07323680) | Rhoshan Pharmaceuticals Inc | 2025-06-15 |
| Phase 1 Dexlansoprazole Delayed-Release Capsules for Acid-Related Disorders in Infants Aged 1 to 11 Months (NCT02442752) | Takeda | 2025-06-15 |
| A Study to Evaluate Eciskafusp Alfa in Combination With Bacillus Calmette-guerin (BCG) in Participants With BCG-unresponsive High-risk Non-muscle Invasive Bladder Cancer (NMIBC) (NCT06816017) | Hoffmann-La Roche | 2025-06-15 |
| Comparing the Availability of AQ280 in the Body After Single Oral Doses of a Capsule Formulation Versus a Tablet for Oral Suspension Formulation (NCT07093008) | AQILION AB | 2025-06-13 |
| A Trial to Test the Safety and Tolerability of Lu AH69593 in Adults That Are Healthy or Have Narcolepsy (NCT07613710) | H. Lundbeck A/S | 2025-06-13 |
| MK2 Inhibitor in Combination With mFOLFIRINOX for Untreated Metastatic Pancreatic Ductal Adenocarcinoma (NCT06648434) | Washington University School of Medicine | 2025-06-13 |
| Investigation of Small Mobile Stem Cells (SMS Cells) in Participants With Chronic Obstructive Pulmonary Disease (COPD). (NCT06986070) | SMSbiotech | 2025-06-13 |
| A Study to See How Safe a New Medicine (NNC0705-0001) is in Healthy People (NCT07029568) | Novo Nordisk A/S | 2025-06-13 |
| Phase I Study of XTL6001 Injection in Healthy and Obese Subjects (NCT07205432) | Shanghai Xitaili Biomedicine Technology co., Ltd. | 2025-06-13 |
| Qingre Huatan Formula for the Prevention of Early Neurological Deterioration in Acute Ischemic Stroke (NCT06857487) | Dongzhimen Hospital, Beijing | 2025-06-13 |
| A Phase I First-in-Human Open-Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-Tumor Activity of SWA1211 Tablets in Subjects With Advanced Solid Tumors (NCT07363967) | Beijing StoneWise Technology Co., Ltd | 2025-06-13 |
| A Study of TAK-007 in Adults With Refractory Lupus Nephritis (LN) or Refractory Systemic Sclerosis (SSc) (NCT06377228) | Takeda | 2025-06-13 |
| A Study to Assess the Relative Bioavailability of Risankizumab Following Subcutaneous Administrations With a Pre-Filled Syringe or an On-Body Injector in Healthy Adult Participants (NCT07007091) | AbbVie | 2025-06-12 |
| A Phase 1 Study Evaluating Safety, Tolerability, and Pharmacokinetics of VX-407 in Healthy Participants (NCT07022119) | Vertex Pharmaceuticals Incorporated | 2025-06-12 |
| Testing the Addition of an Anti-cancer Drug, DT2216, to the Usual Chemotherapy Treatment for Relapsed or Refractory Solid Tumors and Fibrolamellar Carcinoma (NCT06620302) | Children's Oncology Group | 2025-06-12 |
| TherVacB - A Heterologous Protein Prime/MVA Boost Therapeutic Hepatitis B Vaccine Candidate (NCT06513286) | Michael Hoelscher | 2025-06-12 |
| A Study on Oral and Intranasal Forms of Oxycodone in Healthy Volunteers Using Pharmacokinetic Modeling (NCT07223450) | Parc de Salut Mar | 2025-06-12 |
| The Role of the Amylin Analogue Cagrilintide in Bone Metabolism (NCT07010432) | Novo Nordisk A/S | 2025-06-12 |
| Safety and Efficacy of TimoD Sustained-Release Implant in Participants With Glaucoma or Ocular Hypertension Undergoing Cataract Surgery (NCT07036510) | EyeD Pharma | 2025-06-12 |
| A Study to Assess the Time to Onset of Action of Staccato Alprazolam Versus Midazolam and Diazepam in Healthy Participants (NCT07020988) | UCB Biopharma SRL | 2025-06-12 |
| A Study of GSK5458514 Administered Alone or In Combination With Other Anti-Cancer Agents in Participants With Prostate Cancer (NCT06990880) | GlaxoSmithKline | 2025-06-12 |
| NT219 Combined With Standard of Care Biologic Therapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (NCT06919666) | University of Colorado, Denver | 2025-06-12 |
| Clinical Trial of YH32364 in Patients With Locally Advanced or Metastatic EGFR Overexpressing Solid Tumors (NCT06975410) | Yuhan Corporation | 2025-06-12 |
| Clinical Trial of CD19 Targeted CAR-T Cell in Refractory Adult SLE (NCT06892145) | Chongqing Precision Biotech Co., Ltd | 2025-06-12 |
| A Study to Evaluate the Safety and Immunogenicity of Two Doses of a Novel H5 Central Antigen mRNA-LNP in Healthy Adults (NCT07019883) | National Institute of Allergy and Infectious Diseases (NIAID) | 2025-06-12 |
| Low-grade UTUC Treated With Nadofaragene Firadenovec Administered to Renal Pelvis (NCT06668493) | Ferring Pharmaceuticals | 2025-06-12 |
| A Phase 1 Study of SSGJ-709 in Patients With Advanced Malignant Tumors (NCT07016490) | Shenyang Sunshine Pharmaceutical Co., LTD. | 2025-06-12 |
| NWRD09 for HPV-16 Related Cervical HSIL (NCT07047989) | Newish Biotech (Wuxi) Co., Ltd. | 2025-06-12 |
| A Phase 1 Study of TGI-5 as Monotherapy and in Combination With Nivolumab in Subjects With Locally Advanced/Metastatic Solid Tumors (NCT07376707) | Hefei TG ImmunoPharma Co., Ltd. | 2025-06-12 |
| An Ascending Dose Study of PIT565 in Participants With Rheumatoid Arthritis (NCT07029555) | Novartis Pharmaceuticals | 2025-06-12 |
| Follow-up Study to Evaluate the Safety and Efficacy of FCN-159 in Pediatric Participants With Neurofibromatosis Type 1 (NCT07024394) | Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. | 2025-06-12 |
| A Phase 1 Study to Investigate FP008 in Subjects With Advanced Solid Tumors (NCT06990698) | Zhuhai Fapon Biopharma Co., Ltd. | 2025-06-12 |
| A Study to Test the Safety and Effectiveness of GSK5764227, Alone or With Other Treatments, in Participants With Advanced Gastrointestinal Cancers That Cannot be Surgically Removed (EMBOLD PanGI-201) (NCT06885034) | GlaxoSmithKline | 2025-06-11 |
| Safety Study of a Single Dose of Pneumococcal Whole-Cell Vaccine in Healthy Adults (NCT07059182) | Serum Life Science Europe GmbH | 2025-06-11 |
| A Study to Learn How BIIB141 (Omaveloxolone) is Processed in the Body When Taken as Capsules Compared to Sprinkled on Yogurt in Healthy Adults Aged 18 to 55 (NCT07019064) | Biogen | 2025-06-11 |
| A Study of Inhaled AZD8630 in Adolescents With Asthma (NCT07065331) | AstraZeneca | 2025-06-11 |
| Study of HX15001 in Adult Healthy Volunteers. (NCT06999720) | Helixon Biotechnology (Suzhou) Co., Ltd | 2025-06-11 |
| A Clinical Trial of SIBP-A19 Injection in the Treatment of Advanced Malignant Solid Tumor Patients (NCT06990464) | Shanghai Institute Of Biological Products | 2025-06-11 |
| Right Tools, Right Time, Right Place: Telehealth for Opioid Use Disorder in Vulnerable Settings (NCT07169409) | Boulder Care | 2025-06-10 |
| Phase I Trial on the Safety of Delayed Infusion of a Naïve T Cell-Depleted Hematopoietic Graft With Memory T Cells in Solid Organ Transplant Recipients (NCT06997471) | Francisco Hernández Oliveros | 2025-06-10 |
| To Evaluate the Tolerability, Pharmacokinetics, and Pharmacodynamics of IMM-H014 in Patients With MASH (NCT07016633) | Changchun Intellicrown Pharmaceutical Co. LTD | 2025-06-10 |
| A Clinical Trial of Neoadjuvant Targeted Therapy, Immunotherapy, and Lysogenic HSV-Based Virotherapy in Resectable Head and Neck Squamous Cell Carcinoma (NCT07010120) | West China Hospital | 2025-06-10 |
| Hepatic Artery Transfusion of NKG2D CAR-NK Cells Followed by Intravenous Infusion of NKG2D CAR-T Cells to Treat Patients With Advanced Solid Tumors With Liver Metastases Who Have Failed Standard Treatments: a Phase I Exploratory Clinical Trial (NCT07021534) | Zhejiang University | 2025-06-10 |
| A First-in-human Study to Assess OT-C001 (Amplified/Activated Allogenic Natural Killer Cells) in Patients With Relapsed/Refractory Diffuse Large B Cell Lymphoma (NCT07044050) | Emercell SAS | 2025-06-10 |
| A Phase I First-in-Human Study of GenSci128 in Patients With Solid Tumors Harboring a TP53 Y220C Mutation (NCT06908434) | Changchun GeneScience Pharmaceutical Co., Ltd. | 2025-06-10 |
| Evaluate Efficacy, Safety, Tolerability and Biodegradation of PA5346 Ocular Implant in Patients With Open-Angle Glaucoma or Ocular Hypertension (NCT06964061) | PolyActiva Pty Ltd | 2025-06-10 |
| A Study to Investigate Safety and Effectiveness of Porcine Pancreatic Cells (OPF-310) in Patients With Type 1 Diabetes Mellitus (NCT06575426) | Otsuka Pharmaceutical Factory, Inc. | 2025-06-10 |
| Role of Metal Ion Transporter ZIP8 in Alcohol-Related Behaviors (NCT06819189) | National Institute on Alcohol Abuse and Alcoholism (NIAAA) | 2025-06-10 |
| Phase 1/2 Study of ETX-636 in Participants With Advanced Solid Tumors (NCT06993844) | Ensem Therapeutics | 2025-06-10 |
| A Phase 1 Study of Mosliciguat in Healthy, Adult Males (NCT07185321) | Pulmovant, Inc. | 2025-06-10 |
| Immunotherapy For Adults With GPC3-Positive Solid Tumors Using IL-15 and IL-21 Armored GPC3-CAR T Cells (NCT06198296) | Baylor College of Medicine | 2025-06-10 |
| A Study of LY3981314 in Healthy Participants (NCT07005284) | Eli Lilly and Company | 2025-06-09 |
| A Study to Investigate Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AZD4248 in Healthy Participants and Participants With Chronic Kidney Disease and Type 2 Diabetes and to Assess Home Measurements of Creatinine in a Non Interventional Cohort (NCT07024823) | AstraZeneca | 2025-06-09 |
| A Study of Almonertinib Combined With Palbociclib in Patients With Advanced Solid Tumors Harboring KRAS Mutations (NCT06947811) | Sun Yat-sen University | 2025-06-09 |
| A Phase 1b/2 Study of Intravenous Brincidofovir in Patients With Relapsed or Refractory Lymphoma and Relapsed or Refractory Extranodal Natural Killer/T-cell Lymphoma (NCT06761677) | SymBio Pharmaceuticals | 2025-06-09 |
| A Clinical Study of GenSci134 in Healthy Adults and Adult Growth Hormone Deficiency(AGHD) (NCT07016802) | Changchun GeneScience Pharmaceutical Co., Ltd. | 2025-06-09 |
| Nelmastobart in Combination With Trifluridine/ Tipiracil and Bevacizumab in Metastatic/ Recurrent Colorectal Cancer (NCT06873763) | STCube, Inc. | 2025-06-09 |
| SAL0140 Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study in a Healthy Chinese Population (NCT07051603) | Shenzhen Salubris Pharmaceuticals Co., Ltd. | 2025-06-09 |
| A Phase I Study of SHR-4712 in Patients With Advanced Solid Tumors (NCT06993116) | Guangdong Hengrui Pharmaceutical Co., Ltd | 2025-06-09 |
| A Study on the Bioequivalence of Bupivacaine Liposome Injection in Humans (NCT07279155) | Jiangsu HengRui Medicine Co., Ltd. | 2025-06-09 |
| Safety and Tolerability of CMAB017 In Patients With Advanced Solid Tumors (NCT06933069) | Taizhou Mabtech Pharmaceutical Co.,Ltd | 2025-06-09 |
| A Study Evaluating the Safety, Tolerability and Pharmacokinetics of ASY202 in Healthy Adults (NCT07226362) | Aspeya Switzerland SA | 2025-06-09 |
| A Study to Evaluate the Safety and Clinical Activity of GF- CART01 (CD20/19 CAR T Cell) in Subjects With Relapsed or Refractory B-Cell Hematological Malignancies (NCT06703892) | GenomeFrontier Therapeutics TW Co., Ltd. | 2025-06-09 |
| A Study on the Effect of Etavopivat on Heart Rhythm in Healthy Participants (NCT07023029) | Novo Nordisk A/S | 2025-06-09 |
| Combining Esketamine and Prolonged Exposure Treatment for PTSD (Post Traumatic Stress Disorder) (NCT06795659) | The University of Texas Health Science Center at San Antonio | 2025-06-09 |
| A Clinical Trial Evaluating the Safety and Tolerability, Biodistribution and Radiation Dosimetry, and Pharmacokinetics of Flotufolastat F-18 Injection in Healthy Chinese Adults (NCT07149831) | Sinotau Pharmaceutical Group | 2025-06-07 |
| Multi-antigen Specific CD8+ T Cells With Decitabine and Lymphodepleting Chemotherapy for the Treatment of Patients With Relapsed or Refractory AML or MDS Following an Allogeneic Hematopoietic Cell Transplantation From a Matched Donor (NCT06572631) | City of Hope Medical Center | 2025-06-07 |
| A Study to Learn About PRT-064040 Nasal Spray in Healthy Adult Subjects (NCT07016516) | Sichuan Purity Pharmaceutical Technology Co., Ltd. | 2025-06-07 |
| A Study to Investigate the Response of Participants With Type 2 Diabetes Mellitus on Once-Weekly Retatrutide to Hypoglycemia (NCT06982846) | Eli Lilly and Company | 2025-06-06 |
| A Study to Evaluate the Safety and Efficacy of PN20 in the Treatment of Thrombocytopenia in Patients With Chronic Liver Disease Undergoing an Elective Procedure (NCT07446491) | Chongqing Peg-Bio Biopharm Co., Ltd. | 2025-06-06 |
| Bioequivalence Study of Azilsartan Medoxomil 80 mg Tablets (Gedeon Richter Plc., Hungary) and Edarbi® 80 mg Tablets (JSC Nizhpharm, Russia) (NCT06990204) | Gedeon Richter Plc. | 2025-06-06 |
| A Trial to Evaluate the Safety, Tolerability and Preliminary Efficacy of NCR201 in the Treatment of Subjects With Parkinson's Disease (NCT06978920) | Nuwacell Biotechnologies Co., Ltd. | 2025-06-06 |