| MK-4646 Multiple Dose Trial in Participants With Human Immunodeficiency Virus Type 1 (HIV-1) (MK-4646-003) (NCT07042945) | Merck Sharp & Dohme LLC | 2025-07-09 |
| Investigation of Drug-drug Interaction of HRS-5965 With Clopidogrel and Clarithromycin in Healthy Subjects (NCT07040787) | Chengdu Suncadia Medicine Co., Ltd. | 2025-07-08 |
| Phase I Clinical Trial of CART Cell Therapy for Refractory/Relapsed Acute Lymphoblastic Leukemia in Children, Adolescents and Young Adults (NCT06709469) | Instituto de Investigación Hospital Universitario La Paz | 2025-07-08 |
| A Clinical Study Exploring CT1190B in the Treatment of Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma ( CT1190B-CG1101 ) (NCT07032324) | Qian Wenbin | 2025-07-08 |
| Comparison of 177Lu-PSMA-617 and 225Ac-PSMA-617 (NCT07054346) | Thomas Hope | 2025-07-08 |
| Study of KM-023 in Healthy Volunteers and Patients With Olmsted Syndrome. (NCT07090889) | Orvida Pharma (formerly Kamari Pharma) | 2025-07-08 |
| Pancoronavirus Vaccine Study in Healthy Adults (NCT06950177) | Duke University | 2025-07-08 |
| Anti-Mesothelin TNaive/SCM hYP218 (TNhYP218) CAR T Cells in Participants With Mesothelin-Expressing Solid Tumors Including Mesothelioma (NCT06885697) | National Cancer Institute (NCI) | 2025-07-08 |
| Peptide Vaccine for Fibrolamellar Hepatocellular Carcinoma Patients and Other Tumor Entities Carrying the Driver Fusion DNAJB1-PRKACA (NCT06789198) | University Hospital Tuebingen | 2025-07-08 |
| A Study to Determine the Safety and Tolerability of AG-236 and How it is Absorbed, Broken Down, and Eliminated From the Body in Healthy Participants (NCT07075640) | Agios Pharmaceuticals, Inc. | 2025-07-07 |
| TGRX-678 Pharmacokinetic Mass Balance (NCT06986772) | Shenzhen TargetRx Co., Ltd. | 2025-07-07 |
| RN1201 Injection in the Treatment of Antibody-Mediated Diseases (NCT07072247) | The First Affiliated Hospital of Soochow University | 2025-07-07 |
| CDC-9 Inactivated Rotavirus Vaccine (IRV) Microneedle Patch (MNP) in Healthy Adults (NCT06962904) | Centers for Disease Control and Prevention | 2025-07-07 |
| A Phase 1/2 Study of the Safety and Efficacy of BRX011 Oral Administration Once Daily in Subjects With Geographic Atrophy Secondary to Age-Related Macular Degeneration (NCT07029945) | Biojiva LLC | 2025-07-07 |
| Phase I/II Clinical Trial of Proteasome Inhibitor in Combination With CPX-351 for the Treatment of Newly-Diagnosed TP53-mutated Acute Myeloid Leukemia (AML) (NCT07008638) | Masonic Cancer Center, University of Minnesota | 2025-07-07 |
| Assessing the Safety, Immunogenicity and Ex-vivo Efficacy of Two Candidate Malaria Transmission Blocking Vaccines, Pfs25-IMX313 and Pfs45/48 Administered Alone and in Combination, in Matrix-M Adjuvant (NCT06549257) | University of Oxford | 2025-07-07 |
| Feasibility, Safety, and Potential Efficacy of Fecal Microbiota Transplantation (FMT) for Gastrointestinal Dysfunction in Children Following Hematopoietic Cell Transplant (HCT). (NCT05664113) | St. Jude Children's Research Hospital | 2025-07-07 |
| Clinical Trial Comparing Single-administration of DA-5222 and Co-administration of DA-5222-R1, DA-5222-R2 and DA-5222-R3 in Healthy Adult Subjects in Fed State (NCT07046715) | Dong-A ST Co., Ltd. | 2025-07-07 |
| An Exploratory Study on NK Cell-assisted Prevention of Bone Marrow Suppression During Chemotherapy for Ovarian Cancer (NCT07096583) | Anhui Provincial Cancer Hospital | 2025-07-07 |
| A Study Comparing KB801 Verse Placebo in Patients With Stage 2 or 3 Neurotrophic Keratitis (NCT06999733) | Krystal Biotech, Inc. | 2025-07-07 |
| A Study of JNJ-78278343 in Combination With JNJ-95298177 for Treatment of Prostate Cancer (NCT07082920) | Janssen Research & Development, LLC | 2025-07-07 |
| Trametinib Treatment for Complicated Vascular Anomalies (NCT07072403) | West China Hospital | 2025-07-07 |
| A Study to Evaluate VH4524184 Tablet Absorption, Effects of Food, and Interactions With Other Drugs in Healthy Adults (NCT07066722) | ViiV Healthcare | 2025-07-07 |
| A Clinical Trial to Evaluate the Safety and Immunogenicity of Glycan-trimmed HIV-1 Nanoparticle Vaccine (UVAX-1107), Followed by Homologous or Wild-type HIV-1 Nanoparticle Vaccine (UVAX-1197) Boost, Each Adjuvanted With 3M-052-AF + Alum in Adult Participants Without HIV (NCT06905275) | National Institute of Allergy and Infectious Diseases (NIAID) | 2025-07-07 |
| A Study to Evaluate the Effect of XY0206 on the QTc Interval in Chinese Healthy Participants (NCT07162116) | Shijiazhuang Yiling Pharmaceutical Co. Ltd | 2025-07-06 |
| A Study to Learn About How Safe and Effective is 20vPnC and 13vPnC Vaccines in Chinese Adults (NCT07019909) | Pfizer | 2025-07-06 |
| A Study to Evaluate the Pharmacokinetics and Safety Between "BR3006" and Co-administration of "BR3006A", "BR3006B", and "BR3006C" in Healthy Adult Volunteers (Fed) (NCT07083401) | Boryung Pharmaceutical Co., Ltd | 2025-07-05 |
| A Study to Compare and Evaluate the Safety, Tolerability and Pharmacokinetics Between DA-5223 and DA-5223-R in Healthy Adult Subjects (NCT07007533) | Dong-A ST Co., Ltd. | 2025-07-04 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Preliminary Antitumor Activity of INV-6452 in Adult Patients With Hormone Receptor Positive, Human Epidermal Growth Factor Receptor 2 Negative (HR+/HER2-) Advanced/Metastatic Breast Cancer or Locally Advanced/Metastatic Solid Tumor (NCT07612891) | Shenzhen Ionova Life Sciences Co., Ltd. | 2025-07-04 |
| Study of HC006 in Combination With a PD-1 Inhibitor in Patients With Advanced Solid Tumors (NCT06963814) | HC Biopharma Inc. | 2025-07-04 |
| Clinical Study of U32 in Patients With Acute Myeloid Leukemia (NCT07036250) | Shanghai Unicar-Therapy Bio-medicine Technology Co.,Ltd | 2025-07-03 |
| Study to Evaluate Safety, Efficacy and Immunogenicity of Acne mRNA Vaccine in Participants With Mild Acne (NCT07013747) | Sanofi Pasteur, a Sanofi Company | 2025-07-03 |
| Study of FID-022 in Participants With Advanced Solid Tumors (NCT06694480) | Fulgent Pharma LLC. | 2025-07-03 |
| Master Protocol of TCR-modified T Cell Therapy Targeting HLA-restricted KRAS Antigen Administered in Adult Patients With Metastatic or Locally Advanced PDAC (NCT07145450) | Anocca AB | 2025-07-03 |
| Imaging of Solid Tumors Using 18F-TRX (NCT06942104) | Rahul Aggarwal | 2025-07-03 |
| A Clinical Trial of CAP-002 Gene Therapy in Pediatric Patients With Syntaxin-Binding Protein 1 (STXBP1) Encephalopathy (NCT06983158) | Capsida Biotherapeutics, Inc. | 2025-07-03 |
| A Clinical Study of How Coffee and Tea Affect Enlicitide in Healthy Volunteers (MK-0616-040) (NCT07044479) | Merck Sharp & Dohme LLC | 2025-07-03 |
| A Study to Evaluate the Pharmacokinetics and Safety Between "BR3006" and Co-administration of "BR3006A", "BR3006B", and "BR3006C" in Healthy Adult Volunteers (Fasting) (NCT07083388) | Boryung Pharmaceutical Co., Ltd | 2025-07-03 |
| High Potency Cannabis: Acute and Protracted Effects (NCT06859723) | University of California, Los Angeles | 2025-07-03 |
| A Clinical Study of Ifinatamab Deruxtecan Based Treatment Combinations or as Monotherapy to Treat Metastatic Castrate Resistant Prostate Cancer (mCRPC) (MK-2400-01A/IDeate-Prostate02) (NCT06863272) | Merck Sharp & Dohme LLC | 2025-07-03 |
| Multiple Dose Intraventricular Administration of Rhenium-186 NanoLiposome for Leptomeningeal Metastases (NCT07098806) | Plus Therapeutics | 2025-07-02 |
| A Study of KITE-363 in Participants With Refractory Autoimmune Diseases (NCT07038447) | Kite, A Gilead Company | 2025-07-02 |
| A Study in Healthy Men to Compare the Amount of Vicadrostat and Empagliflozin in the Blood When Taken Separately and Together (NCT07035457) | Boehringer Ingelheim | 2025-07-02 |
| A First-in-Human Study of YL217 in Patients With Advanced Solid Tumors (NCT06859762) | MediLink Therapeutics (Suzhou) Co., Ltd. | 2025-07-02 |
| Safety and Early Efficacy of iPSC-Derived Motor Neuron Progenitor Cells (XS228) in Subacute Spinal Cord Injury: A Phase I Trial (NCT06976229) | XellSmart Bio-Pharmaceutical (Suzhou) Co., Ltd. | 2025-07-02 |
| A Study of AK146D1 for Injection in the Treatment of Advanced Solid Tumors (NCT06929663) | Akeso | 2025-07-02 |
| Use of Progenitor Biological Bandages in Burn Care (Bru_PBB) (NCT05339490) | Dr Anthony De Buys Roessingh | 2025-07-01 |
| Hyaluronic Acid in the Treatment of Hyposalivation (NCT07309588) | Poznan University of Medical Sciences | 2025-07-01 |
| Safety and Immunogenicity of PCV-LITE, a Low-dose of Pneumococcal Conjugate Vaccine With LiteVax Adjuvant (NCT06986239) | LiteVax BV | 2025-07-01 |
| Efficacy of Microneedling With Vitamin C in Performing Gingival Depigmentation (NCT07070024) | Fayoum University | 2025-07-01 |
| A Study of QLS5133 Monotherapy in Advanced Solid Tumors (NCT07061639) | Qilu Pharmaceutical Co., Ltd. | 2025-07-01 |
| A Study of SH006 Injection Combination Therapy in Patients With Advanced Solid Tumors (NCT07362264) | Nanjing Sanhome Pharmaceutical, Co., Ltd. | 2025-07-01 |
| Pharmacokinetics and Pharmacodynamics Study (NCT07074236) | Qilu Pharmaceutical Co., Ltd. | 2025-07-01 |
| Phase 1b/2a Trial of Allogeneic HSCT From an HLA-partially Matched Related or Unrelated Donor After TCRab+ T-cell/CD19+ B-cell Depletion for Patients With Monogenic and/or Early-onset Medically Refractory Crohn Disease (NCT06986382) | Stanford University | 2025-07-01 |
| EPITOME-1015-I: a Study to Investigate the Safety and Tolerability of MDG1015 in Patients with Epithelial Ovarian Cancer, Gastroesophageal Adenocarcinoma, Round Cell Liposarcoma And/or Synovial Sarcoma (NCT06748872) | Medigene AG | 2025-07-01 |
| Treatment Planning for ABA Employing Auxiliary Tools V2+ (TREAAT2+) (NCT06204536) | Montera Health Texas LLC | 2025-07-01 |
| Influence of Standardized Perioperative Anesthetic, Analgesic Care on Outcome of Patients Undergoing Hip Fracture Surgeries (NCT06925789) | Milton S. Hershey Medical Center | 2025-07-01 |
| Ambulatory Flexible URS for UTUC Surveillance (NCT06848868) | Chinese University of Hong Kong | 2025-07-01 |
| A Drug Drug Interaction Study to Evaluate the Effect of VCT220 on the Pharmacokinetics of Repaglinide, Rosuvastatin, and Digoxin in Healthy, Overweight, and Obese Subjects (NCT07065058) | Vincentage Pharma Co., Ltd | 2025-07-01 |
| A Study to See the Effect of NNC0194-0499 Alone or in Combination With Semaglutide on Blood Sugar Control in People Living With Type 1 Diabetes (NCT07087795) | Novo Nordisk A/S | 2025-07-01 |
| TRT as an Adjunctive ERAS Therapy in ESRD Patients Undergoing Kidney Transplantation (NCT07287800) | University of California, Los Angeles | 2025-07-01 |
| A Study of Two Different Formulations of 611 in Healthy Adult Subjects in China (NCT07042113) | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | 2025-07-01 |
| The Safety, Tolerability, and Efficacy of IBR900 Cell Injection in Relapsed/Refractory B-cell Non Hodgkin Lymphoma (NCT07073833) | Imbioray (Hangzhou) Biomedicine Co., Ltd. | 2025-07-01 |
| Phase I/II Clinical Study of HRS-1738 for the Diagnosis of Prostate Cancer Patients (NCT07056439) | Jiangsu HengRui Medicine Co., Ltd. | 2025-07-01 |
| Experimental Malaria Infection of Healthy Malaria-Naive Adults by Mosquito Bite With the Genetically Modified Plasmodium Falciparum NF54/iGP3 GAP (NCT06881732) | University of Melbourne | 2025-07-01 |
| The Safety, Efficacy, and Cellular Metabolic Kinetics of CT1192 in Treating Patients With Anti Neutrophil Cytoplasmic Antibody Associated Vasculitis (NCT07033299) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2025-07-01 |
| Surgery for Relapsed Ovarian Cancer in Precision (NCT06602063) | Shanghai Gynecologic Oncology Group | 2025-07-01 |
| Comparison of the Outcome of Treatment With Silymarin or N-Aceylcysteine in Patients Taking Anti-Tuberculous Drugs for Tuberculosis at a Tertiary Care Hospital , Karachi (NCT07058090) | Liaquat National Hospital & Medical College | 2025-07-01 |
| EDP167 in Healthy Volunteers and Subjects With Mild Dyslipidemia (NCT07412080) | Eddingpharm (Zhuhai) Co., Ltd. | 2025-07-01 |
| Safety and Preliminary Efficacy of TrophiPatch, an Adipose-Derived Stromal Cell Patch for Chronic Leg Ulcers (NCT07048054) | Nicolò Brembilla | 2025-07-01 |
| Safety Of A Second Dose Of Tenecteplase In Selected Acute Ischemic Stroke Patients Not Responding To The First Dose (NCT06801054) | Memorial Hermann Health System | 2025-07-01 |
| Melatonin in Breast Cancer Patients Receiving Neoadjuvant Chemotherapy (NCT07067307) | Mansoura University | 2025-07-01 |
| 225Ac-DOTA-Anti-CD38 Daratumumab Monoclonal Antibody With Fludarabine, Melphalan and Total Marrow and Lymphoid Irradiation as Conditioning Treatment for Donor Stem Cell Transplant in Patients With High-Risk Acute Myeloid Leukemia, Acute Lymphoblastic Leukemia and Myelodysplastic Syndrome (NCT06287944) | City of Hope Medical Center | 2025-07-01 |
| JWCAR239 in Patients With B Cell Non-Hodgkin Lymphoma (NCT07024147) | Peking University Cancer Hospital & Institute | 2025-07-01 |
| Safety of BBC1501 Intravitreal Injection in Patients With Neovascular Age-Related Macular Degeneration (nAMD) (NCT05803785) | Benobio Co., Ltd. | 2025-07-01 |
| Phase 1 Clinical Study of GT-220F in Subjects With Metastatic Castration Resistant Prostate Cancer (mCRPC) (NCT06866795) | Geode Therapeutics Inc. | 2025-07-01 |
| Remimazolam Infusion in Kidney Transplant Patients: A Multicenter Study (NCT07045467) | Qianfoshan Hospital | 2025-07-01 |
| Excretion of Rivaroxaban in Human Breast Milk (NCT06831474) | Thomas Jefferson University | 2025-07-01 |
| Personalized mRNA Cancer Vaccine for Gastrointestinal Solid Tumor Treatment (NCT07067385) | Ruijin Hospital | 2025-07-01 |
| Study of 225Ac-SS0110 in Subjects With ES-SCLC or MCC (SANTANA-225 ) (NCT06939036) | Ariceum Therapeutics GmbH | 2025-07-01 |
| Testing How the Body Responds to the Drug CX-5461 (Pidnarulex) in Patients With Metastatic Solid Cancers (NCT06606990) | National Cancer Institute (NCI) | 2025-07-01 |
| Safety and Efficacy of Universal CD19-targeting CAR-γδT Cells in Refractory Autoimmune Diseases (NCT06828042) | Peking University Third Hospital | 2025-07-01 |
| A Phase I Study of the Interaction of Alcohol With Oral AFA-281 in Healthy Volunteers (NCT06719908) | Afasci Inc | 2025-07-01 |
| Immunotherapy Based on Tumor Associated Antigen-specific Immune Effector Cells (NCT03535246) | Shenzhen Geno-Immune Medical Institute | 2025-07-01 |
| Irreversible Electroporation (NanoKnife ®) and Immunotherapy for the Treatment of Stage IV Colorectal Cancer (NCT06047015) | University of Saskatchewan | 2025-07-01 |
| Immunotherapy Treating GI Cancer (NCT03614650) | Shenzhen Geno-Immune Medical Institute | 2025-07-01 |
| hUC-MSC-sEV-001 Nasal Drops for Neurodegenerative Diseases (NCT06607900) | Xuanwu Hospital, Beijing | 2025-07-01 |
| Repurposing 5-Azacytidine for the Treatment of Muscle Contractures in Children With Cerebral Palsy (NCT06377085) | Shirley Ryan AbilityLab | 2025-07-01 |
| Safety and Efficacy of Oral HX9428 Tablets in Subjects With Wet Age-related Macular Degeneration (wAMD) (NCT07185841) | Fujian Haixi Pharmaceuticals Co., Ltd. | 2025-07-01 |
| In VIVO CAR-T Therapy for Relapsed/Refractory Hematological Malignancies (NCT07239323) | Chongqing Precision Biotech Co., Ltd | 2025-07-01 |
| Dose Optimization and Efficacy Assessment of a Fluoropyrimidine Antidote (NCT07032142) | D'Or Institute for Research and Education | 2025-07-01 |
| The Effects of Cannabidiol on the Driving Performance of Healthy Adults by Dose and Sex (NCT06686914) | West Virginia University | 2025-06-30 |
| A Study of ORX142 in Healthy Adult Subjects, Including Subjects 18 to 80 Years of Age (NCT07082829) | Centessa Pharmaceuticals (UK) Limited | 2025-06-30 |
| A Study to Assess the Safety and Effects of the Investigational Drug BW-40202 in Healthy Volunteers (NCT06917482) | Shanghai Argo Biopharmaceutical Co., Ltd. | 2025-06-30 |
| Phase I Clinical Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics of NTB003 in Healthy Participants (NCT07182552) | Nanjing Chia-tai Tianqing Pharmaceutical | 2025-06-30 |
| Safety Of Nrtis for Alzheimer's Therapeutic Advancement in Singapore Study (NCT07210528) | National University Hospital, Singapore | 2025-06-30 |
| Feasibility of a Digital Therapeutic for Adults With Posttraumatic Stress Disorder (PTSD) (NCT06868446) | Oui Therapeutics, Inc. | 2025-06-30 |
| A Phase I Randomised, Double-Blind, Placebo-Controlled, Single and Multiple Ascending Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect of WD-910 in Healthy Participants (NCT06897813) | Zhejiang Wenda Pharma Technology LTD. | 2025-06-30 |
| Golcadomide and Nivolumab in Patients With Non-Hodgkin Lymphoma With Refractory Disease After Chimeric Antigen T-cell Therapy (NCT06767956) | University of Pittsburgh | 2025-06-30 |
| A Study in Participants With Duchenne Muscular Dystrophy Amenable to Exon 44 Skipping to Evaluate the Safety and Efficacy of ENTR-601-44 (NCT07037862) | Entrada Therapeutics, Inc. | 2025-06-30 |