| Oral Arsenic (ATO) in Low-risk Myelodysplastic Syndromes (MDS) (NCT06670222) | Groupe Francophone des Myelodysplasies | 2025-07-22 |
| A Early Study of ABSK131 in Patients With Advanced/Metastatic Solid Tumors (NCT07288957) | Abbisko Therapeutics Co, Ltd | 2025-07-22 |
| A Phase I/Ⅱ Human Study of HY0001a for Injection in Adult Participants With Advanced Solid Tumors (NCT07069062) | Sichuan Huiyu Pharmaceutical Co., Ltd | 2025-07-21 |
| A Clinical Trial to Evaluate the Safety and Efficacy of COM701 in Relapsed Platinum Sensitive Ovarian Cancer (NCT06888921) | Compugen Ltd | 2025-07-21 |
| A Study to Assess the Bioequivalence of Follitropin Alfa Solution in Pen and Follitropin Alfa Powder in Vial in Healthy Downregulated Male Participants (NCT07097259) | EMD Serono Research & Development Institute, Inc. | 2025-07-21 |
| A Study to Evaluate Feasibility, Safety, and Clinical Responses of Implanting Autologous Peripheral Nerve Tissue Into the Brain for Non-motor or Motor Symptoms in Patients With Parkinson's Disease Undergoing DBS Surgery (NCT06683378) | Craig van Horne, MD, PhD | 2025-07-21 |
| A Study to Evaluate Single Doses of Alpha-0261 in Healthy Adult Volunteers (NCT07279636) | AlphaMol Science Ltd. (Shanghai) | 2025-07-21 |
| A Clinical Study on the Safety and Tolerability of PL54 Injection in Adult Patients With Phenylketonuria (PKU) (NCT07672756) | Chongqing Peg-Bio Biopharm Co., Ltd. | 2025-07-20 |
| Evaluation of 627 in Healthy Adult Subjects (NCT07065136) | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | 2025-07-20 |
| This is an Open-label, Non-randomized Study to Assess the Pharmacokinetics (PK) of VCT220 in Healthy Volunteers When Administered With Rifampin or Itraconazole (NCT07056842) | Vincentage Pharma Co., Ltd | 2025-07-20 |
| Substudy 03C: A Study of Combination Therapies in Participants With Renal Cell Carcinoma With Recurrent Disease During or After Anti-PD-(L)1 Therapy (MK-3475-03C/KEYMAKER-U03) (NCT07049926) | Merck Sharp & Dohme LLC | 2025-07-20 |
| CD19 CAR-T Cell Infusion as Consolidation Therapy in Adolescent and Adult Patients With Acute B-ALL Ineligible for Allogeneic HSCT: A Clinical Study (NCT07072494) | Zhujiang Hospital | 2025-07-19 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple-Ascending Doses of BGB-16673 in Adults With Chronic Spontaneous Urticaria (NCT07005713) | BeiGene | 2025-07-19 |
| Phase 1 Single Ascending Dose Study With ATX101 (NCT07107802) | Aurobac Therapeutics SAS | 2025-07-19 |
| Feasibility Study Assessing the Effect of Carbidopa/Levodopa Ratio on Orthostatic Hypotension in Multiple System Atrophy - Parkinsonian Type and Parkinson Disease. (NCT06831500) | Julien Bally | 2025-07-18 |
| A Study to Assess the Effects of BPN14770 on Rosuvastatin (NCT07011992) | Shionogi | 2025-07-18 |
| A Phase I Study of SSGJ-612 in Patients With Advanced Solid Tumors (NCT07032298) | Shenyang Sunshine Pharmaceutical Co., LTD. | 2025-07-18 |
| CART-EGFR-IL13Ra2 in Newly Diagnosed GBM Following Initial Radiotherapy (NCT06973096) | University of Pennsylvania | 2025-07-18 |
| CANnabinoids in Pediatric ONCology (NCT05754840) | University of Manitoba | 2025-07-18 |
| A Clinical Study to Test if an Investigational Treatment Called BNT314 When Used in Combination With Another Investigational Treatment Pumitamig (BNT327) and Chemotherapy, is Beneficial and Safe for Patients With Advanced Colorectal Cancer (NCT07079631) | BioNTech SE | 2025-07-18 |
| NALIRIFOX (Nal-IRI Plus 5-FU/LV Plus Oxaliplatin) as First-Line Treatment for Patients With Advanced Small Intestine and Appendiceal Cancers (NCT07060014) | The Methodist Hospital Research Institute | 2025-07-18 |
| Epcoritamab in Chronic Lymphocytic Leukemia and Richter Syndrome (NCT06676033) | National Heart, Lung, and Blood Institute (NHLBI) | 2025-07-18 |
| Safety and Performance, and Dose, of OsteoAdapt DE in Localized Alveolar Ridge Augmentations (NCT07078331) | Theradaptive, Inc | 2025-07-17 |
| Trial of ProAgio in Advanced/Metastatic Colorectal Cancer (NCT06867822) | University of Alabama at Birmingham | 2025-07-17 |
| Trial of Novel Anti-leukemia Agents in Flu/Mel RIC Transplant for Myeloid Malignancies (NCT07044544) | University of Alabama at Birmingham | 2025-07-17 |
| A Study of MHB046C Injection in Patients With Advanced Solid Tumors (NCT06985355) | Minghui Pharmaceutical (Hangzhou) Ltd | 2025-07-17 |
| A Study to Assess THN391 in Subjects With Alzheimer's Disease (NCT06814730) | Therini Bio, Inc. | 2025-07-17 |
| A Study of LUCAR-G79 in Subjects With Relapsed/Refractory Autoimmune Diseases (NCT07049081) | Nanjing Legend Biotech Co. | 2025-07-17 |
| A Study to Assess Safety and Efficacy of Surgical Implant of RNDP-001 in Patients With Idiopathic Parkinson's Disease (NCT07106021) | Kenai Therapeutics | 2025-07-17 |
| A Study of Subcutaneous Trastuzumab Deruxtecan in Participants With Metastatic Solid Tumors (NCT07015697) | Daiichi Sankyo | 2025-07-17 |
| The Impact of Botox on Neuroimmune Interactions in Atopic Dermatitis (NCT06928246) | Daniel Kaplan | 2025-07-17 |
| Phase I/II Clinical Trial of 26-valent Pneumococcal Conjugate Vaccine (NCT06703203) | Beijing Zhifei Lvzhu Biopharmaceutical Co., Ltd | 2025-07-17 |
| A Study to Test How BI 1291583 is Taken up in the Blood of People With and Without Liver Problems (NCT07023354) | Boehringer Ingelheim | 2025-07-17 |
| Study of Orally Administered MOMA-341 in Participants With Advanced or Metastatic Solid Tumors (NCT06974110) | MOMA Therapeutics | 2025-07-16 |
| A Study of CBX-250 in Participants With Relapsed or Refractory Myeloid Leukemias (NCT06994676) | Crossbow Therapeutics, Inc. | 2025-07-16 |
| Safety and Pharmacokinetics of SAD/MAD Oral Doses of SRP-3D (DA) (NCT05484414) | South Rampart Pharma, LLC | 2025-07-16 |
| DZD6008 Combination Therapy in Patients With Locally Advanced or Metastatic NSCLC With EGFR Mutation (TIAN-SHAN7) (NCT07070440) | Dizal Pharmaceuticals | 2025-07-16 |
| A Study to Evaluate a Novel Gene Therapy in Patients With Relapsed and Refractory Multiple Myeloma (NCT07075185) | Kelonia Therapeutics, Inc. | 2025-07-16 |
| A Study to Evaluate the Pharmacokinetics and Safety of Diluted vs. Undiluted Intravenous DA-5217 in Healthy Adult Subjects (NCT07027982) | Dong-A ST Co., Ltd. | 2025-07-16 |
| A Study to Assess the Effect of Itraconazole, Rifampin, and Acid-Reducing Agents on INCB161734 Pharmacokinetics When Administered Orally in Healthy Participants (NCT07018635) | Incyte Corporation | 2025-07-16 |
| A Study to Investigate Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD), and Immunogenicity of RO7669330 in Participants With Geographic Atrophy (GA) Secondary to Age-related Macular Degeneration (AMD) (NCT06961370) | Hoffmann-La Roche | 2025-07-16 |
| Base Editing Hematopoietic Stem Cell and T Cell Gene Therapy for CD40L-HyperIgM Syndrome: Single Patient Study (NCT06959771) | National Institute of Allergy and Infectious Diseases (NIAID) | 2025-07-16 |
| Neoadjuvant Immunotherapy Combined With Chemotherapy Sequenced With Endoscopic Resection for Esophageal Cancer (Endosurgery-02) (NCT07317609) | Shanghai Zhongshan Hospital | 2025-07-15 |
| A Phase Ia/ Ib Study of HS387 in Subjects With Advanced Solid Tumors (NCT07092748) | Zhejiang Hisun Pharmaceutical Co. Ltd. | 2025-07-15 |
| Phase 1 Study of BAFF CAR-T Cells (LMY-920) for Treatment of Relapsed or Refractory Chronic Lymphocytic Leukemia / Small Lymphocytic Lymphoma (NCT06916767) | Paolo Caimi, MD | 2025-07-15 |
| A Study of JNJ-95437446 in Participants With Advanced-Stage Solid Tumors (NCT07107230) | Janssen Research & Development, LLC | 2025-07-15 |
| Leflunomide in Combination With Decitabine for Treatment of Relapsed or Refractory Myelodysplastic Syndromes (NCT06923488) | West Virginia University | 2025-07-15 |
| Combined Guanfacine and Mindfulness Meditation as an Adjunct to Buprenorphine Maintenance in Opioid Use Disorder (NCT06642181) | Rutgers, The State University of New Jersey | 2025-07-15 |
| Erlotinib in Combination With Select Tyrosine Kinase Inhibitors in Adult Patients With Advanced Solid Tumors (NCT06161558) | National Cancer Institute (NCI) | 2025-07-15 |
| A Phase 1 Study of FIT-CD19-CAR-T Cells in R/R B-ALL (NCT07066397) | TriArm Therapeutics (Taiwan) Limited | 2025-07-15 |
| A Clinical Trial Evaluating Injection of TQB6411 in Subjects With Advanced Malignant Tumors (NCT07043751) | Chia Tai Tianqing Pharmaceutical Group Nanjing Shunxin Pharmaceutical Co., Ltd. | 2025-07-15 |
| The Phase Ib Clinical Trial of the XH-S004 Tablet in Patients With Chronic Obstructive Pulmonary Disease (COPD) to Evaluate Its Safety, Tolerability, Pharmacokinetic Characteristics and Pharmacodynamic Characteristics After Multiple Administrations (NCT07035652) | S-INFINITY Pharmaceuticals Co., Ltd | 2025-07-15 |
| Phase I Study of HMPL-306 for the Treatment of Gliomas With IDH1 and/or IDH2 Mutations (NCT07025018) | Hutchmed | 2025-07-15 |
| A Study to Evaluate Single and Multiple Doses of SEP-631 in Healthy Adult Volunteers (NCT07069036) | Septerna, Inc. | 2025-07-15 |
| A Study to Learn How Different Amounts of the Study Medicine Called PF-07940369 Are Tolerated and Act in the Body in Healthy Adults. (NCT07514156) | Pfizer | 2025-07-15 |
| A Clinical Study Exploring CT1194C in Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma (NCT07068906) | Institute of Hematology & Blood Diseases Hospital, China | 2025-07-15 |
| CAR-T Immunotherapy Targeting CD19- ALL (NCT04016129) | Shenzhen Geno-Immune Medical Institute | 2025-07-15 |
| Effect of Nano-Hyaluronic Acid in Intrabony Defects Treated With Minimally Invasive Non-Surgical Technique (NCT07595757) | Cairo University | 2025-07-15 |
| Effect of HRS-8427 for Injection on the Pharmacokinetics of Furosemide and Metformin in Healthy Subjects。 (NCT07073157) | Jiangsu HengRui Medicine Co., Ltd. | 2025-07-15 |
| Multi-CAR T Cell Therapy for Acute Myeloid Leukemia (NCT03222674) | Shenzhen Geno-Immune Medical Institute | 2025-07-15 |
| ViCToRy: Vorasidenib in Combination With Tumor Specific Peptide Vaccine for Recurrent IDH1 Mutant Lower Grade Gliomas (NCT05609994) | Katy Peters, MD, PhD | 2025-07-15 |
| A Study to Evaluate the Safety and Tolerability of Multiple Dose of IBI3002 in Patients With Atopic Dermatitis (NCT07015762) | The First Affiliated Hospital of Soochow University | 2025-07-14 |
| Safety and Pharmacokinetics of Cannabidiol in Healthy Volunteers (NCT06854783) | Tiamat Australia Pty Ltd | 2025-07-14 |
| A Phase 1 Open-Label Study of the Safety of Intravenous Allogeneic Neonatal Mesenchymal Cells (nMSCs) in Young Adult (1A) and Pediatric (1B) Patients With Dilated Cardiomyopathy (DCM) (NCT06464588) | Emory University | 2025-07-14 |
| A Single-dose Study to Investigate the Effect of Injection Site on KAI-9531 Relative Bioavailability in a Range of Body Mass Indices (NCT07044401) | Kailera | 2025-07-14 |
| Study to Evaluate the Safety and Immunogenicity of Investigational Vaccines Using the RSV (Respiratory Syncytial Virus) Monovalent Antigen in Healthy Participants 18 to 49 Years of Age (NCT07071558) | Sanofi | 2025-07-14 |
| Low Dose Radiotherapy for Heart Failure (NCT07037524) | Hospital do Coracao | 2025-07-14 |
| Invobenitug Also Known as Procizumab (PCZ; AK1967) in Critical Cardiovascular Care (NCT06832722) | 4TEEN4 Pharmaceuticals GmbH | 2025-07-13 |
| A Study to Compare to PK Characteristics and Safety Profiles Between AD-227 and Co-administration of AD-227A and AD-227B (NCT06884085) | Addpharma Inc. | 2025-07-12 |
| A Study to Evaluate the Safety and Pharmacokinetics of AD-228A Compared to Coadministration of AD-2281 and AD-2282 (NCT06858865) | Addpharma Inc. | 2025-07-12 |
| A Trial of SHR-A2102 With Adebrelimab With or Without Other Anti-tumor Therapies in Recurrent/MetastaticHead and Neck Squamous Cell Carcinoma Cancer (NCT07059221) | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | 2025-07-11 |
| Study of GV20-0251 in Participants With Solid Tumor Malignancies (NCT07070518) | GV20 Therapeutics | 2025-07-11 |
| Safety and Pharmacokinetics of Ingavirin Forte, Capsules, 90 mg + 20 mg (Valenta Pharm JSC, Russia) Compared With Ingavirin, Capsules, 90 mg, Under Fasting and Fed Conditions. (NCT07645534) | Valenta Pharm JSC | 2025-07-11 |
| A Study of Multiple Olomorasib (LY3537982) Capsules in Healthy Participants (NCT07044271) | Eli Lilly and Company | 2025-07-11 |
| A Phase 1 Study to Assess Food Effect on the Pharmacokinetics of D3S-001 in Healthy Adult Participants (NCT07093398) | D3 Bio (Wuxi) Co., Ltd | 2025-07-11 |
| Effects of VX-407 on the Pharmacokinetics of Oral Contraceptives in Healthy Participants (NCT07074327) | Vertex Pharmaceuticals Incorporated | 2025-07-11 |
| Safety, Efficacy and Cellular Metabolic Dynamics of ct1192 in Patients With Moderate to Severe Refractory SLE (NCT07031713) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2025-07-11 |
| Pharmacokinetics and Safety of M107 Orally Disintegrating Tablet in Healthy Adults (NCT07056517) | Aclipse Two Inc. | 2025-07-11 |
| A Study to Test How Insulin NNC0471-0119 H Works in the Body in Participants With Type 2 Diabetes When Given by an Insulin Pump (NCT07068295) | Novo Nordisk A/S | 2025-07-11 |
| A Phase 1b Study of Budoprutug in Systemic Lupus Erythematosus (SLE) (NCT07011043) | Climb Bio, Inc. | 2025-07-10 |
| HS-IT101 Injection in the Treatment of Advanced Melanoma (NCT06941818) | Qingdao Sino-Cell Biomedicine Co., Ltd. | 2025-07-10 |
| Intravitreal Adalimumab in Inherited and Degenerative Retinal Diseases (NCT07348588) | Centro de Pesquisa Rubens Siqueira | 2025-07-10 |
| Study Investigating the Safety of CD19 CAR-T Cells in Relapsed/Refractory AML Expressing CD19 (NCT06649227) | University Hospital, Lille | 2025-07-10 |
| A Clinical Study Exploring Universal CAR-T Cell in Patients With Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia (NCT07043218) | Shanghai Tongji Hospital, Tongji University School of Medicine | 2025-07-10 |
| Dose Escalation and Expansion of Ziftomenib in Combination With Quizartinib in Acute Myeloid Leukemia (NCT06769490) | M.D. Anderson Cancer Center | 2025-07-10 |
| A Comparative Pharmacokinetic Study of Single-Dose Administration of HR091506 Tablets From Different Batches in Healthy Subjects (NCT07076459) | Jiangsu HengRui Medicine Co., Ltd. | 2025-07-10 |
| A Phase I/II Study of WJB001 Combination Therapy on Safety and Efficacy for Advanced Solid Tumors (NCT06953323) | Wigen Biomedicine Technology (Shanghai) Co., Ltd. | 2025-07-10 |
| A Study to Investigate the Use of VH3810109 With or Without Fostemsavir (FTR) to Reduce the Size and Activity of the Viral Reservoir in People Living With HIV (NCT07053384) | ViiV Healthcare | 2025-07-10 |
| Safety and Immunogenicity of a Self-Amplifying RNA Vaccine Against Crimean-Congo Hemorrhagic Fever (NCT06799013) | HDT Bio | 2025-07-10 |
| A Study Assessing if it is Safe and Possible to Treat Brain Cancer Patients With Immunotherapy Before They Receive the Standard Treatment. (NCT07134842) | University College, London | 2025-07-10 |
| Study of HS-10516 Combination Therapy in Patients With Advanced Renal Cell Carcinoma (NCT07097935) | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 2025-07-10 |
| JS014 Combined With Toripalimab and TACE in Unresectable HCC: a Phase Ib Study (NCT06882876) | Xiangya Hospital of Central South University | 2025-07-10 |
| Y-3 for Injection in Patients With Hepatic Insufficiency and Healthy Subjects (NCT07055412) | Neurodawn Pharmaceutical Co., Ltd. | 2025-07-10 |
| A Trial of HRS-6213 in Healthy Subjects and Patients With Solid Tumors (NCT07070349) | Jiangsu HengRui Medicine Co., Ltd. | 2025-07-10 |
| A Clinical Study Exploring CT1190B in the Treatment of Patients With Relapsed/Refractory B-cell Non-Hodgkin Lymphoma ( CT1190B-CG11001 ) (NCT07053670) | Tongji Hospital | 2025-07-09 |
| A Ph Ib Study of REGN5678 Plus Cemiplimab in Patients With mCRPC (NCT06826768) | M.D. Anderson Cancer Center | 2025-07-09 |
| EGFR Antibody Combined With PD-1 Inhibitor and Chemotherapy in R/M Nasopharyngeal Carcinoma (NCT06802835) | Sun Yat-sen University | 2025-07-09 |
| A Multicenter, Open-Label, Non-Randomized, Single-Arm Clinical Study of Nanobody CD5-CAR T Cell Therapy for Refractory/Relapsed T Lymphocyte Malignancies (NCT07070323) | Beijing GoBroad Hospital | 2025-07-09 |
| Study of Front Line Pembrolizumab and Valemetostat in PD-L1 Positive, HPV-Negative Recurrent/Metastatic Squamous Cell Carcinoma (SCC) of the Head and Neck: The PANTHERAS (NCT05879484) | National Cancer Institute (NCI) | 2025-07-09 |
| A Study to Assess Zilucoplan Concentration in Breast Milk of Healthy Lactating Women (NCT06961747) | UCB Biopharma SRL | 2025-07-09 |