| A Study of IDE849 in Patients With DLL3 Expressing Tumors Including Small Cell Lung Cancer (NCT07174583) | IDEAYA Biosciences | 2025-10-14 |
| A Study Comparing Tapinarof Cream 1% and Vtama® Cream 1% in the Treatment of Plaque Psoriasis. (NCT07546214) | Sun Pharmaceutical Industries, Inc. | 2025-10-13 |
| Clamp Study to Estimate the Relative Potency of GZR33 Versus Insulin Degludec at Steady State (NCT07242664) | Gan and Lee Pharmaceuticals, USA | 2025-10-13 |
| A Study to Evaluate the Effects of CYP2D6 Phenotypes on the Pharmacokinetics of Xanomeline Following KarXT Administration in Healthy Adult Participants (NCT07204418) | Karuna Therapeutics, Inc., a Bristol Myers Squibb company | 2025-10-13 |
| A Phase I Study to Evaluate the Safety, Tolerability, and Immunogenicity of an mRNA Vaccine Against Herpes Simplex Virus Type 2 (HSV-2) Post-Vaccination (NCT07330440) | Changchun BCHT Biotechnology Co. | 2025-10-13 |
| Phase 1, Open-Label, Randomized, Study of the Safety and Pharmacokinetics of HU6 (NCT07170189) | Rivus Pharmaceuticals, Inc. | 2025-10-13 |
| Study to Demonstrate Pharmacokinetic and Pharmacodynamic Similarity Between NKF-INS(L), US-Humalog®, and EU-Humalog® (NCT07165652) | Xentria, Inc. | 2025-10-13 |
| A Study of CEA-Targeted CAR-T Therapy in Patients With CEA-Positive Advanced Solid Tumors (NCT07250386) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2025-10-13 |
| A Study to Understand What the Body Does to the Study Medicine Called PF-07248144 When Taken by Healthy Adults (NCT07423286) | Pfizer | 2025-10-13 |
| A Study of PRL3-zumab in Neovascular Age-related Macular Degeneration (nAMD) (NCT07547228) | Intra-IMMUSG Pte Ltd | 2025-10-11 |
| A Study of JNJ-89862175 for Treatment of Advanced Solid Tumors (NCT07223125) | Janssen Research & Development, LLC | 2025-10-10 |
| Comparing the Extent to Which Maridebart Cafraglutide (AMG 133) is Made Available in the Body When Administered Using Two Subcutaneous (SC) Presentations (NCT07226778) | Amgen | 2025-10-10 |
| M0324 as Monotherapy and in Combination With Pembrolizumab or Chemotherapy in Participants With Selected Advanced Solid Tumors (NCT07166601) | EMD Serono Research & Development Institute, Inc. | 2025-10-10 |
| A Phase 1 Study of the Safety and Tolerability of Single and Multiple Ascending Doses of BWC0977 in Healthy Volunteers (NCT07029932) | Bugworks Research Inc. | 2025-10-10 |
| GPC-3 CAR T CELLS FOR Recurrent GPC-3 Positive Glioblastoma (NCT06815432) | Baylor College of Medicine | 2025-10-10 |
| A Study to Evaluate the Safety of GR2301 Injection in Healthy Volunteers. (NCT07190716) | Genrix (Shanghai) Biopharmaceutical Co., Ltd. | 2025-10-10 |
| A Phase 1 Study of ADI-001 in Rheumatoid Arthritis (NCT07100873) | Adicet Therapeutics | 2025-10-10 |
| A Safety and Efficacy Study of a One-time Intravitreal Injection of SAR446597 in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration (NCT07215234) | Sanofi | 2025-10-09 |
| Finotonlimab Combined With Stapokibart in the Treatment of Recurrent/Metastatic HNSCC (NCT07040072) | Beijing Tongren Hospital | 2025-10-09 |
| A Clinical Trial of HRS-1301 on the Pharmacokinetics of Rosuvastatin Calcium Tablets in Healthy Subjects (NCT07097831) | Shandong Suncadia Medicine Co., Ltd. | 2025-10-09 |
| Evaluate the Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of BGM1812 Injection Following Single and Multiple Subcutaneous Administration in Normal to Overweight or Obese But Otherwise Healthy Men and Women (NCT07224399) | BrightGene Bio-Medical Technology Co., Ltd. | 2025-10-09 |
| First in Human Dose Escalation Study Evaluating the Safety and Immunogenicity of IVT's Shigella-04 Vaccine in Healthy Young Adults (NCT07205926) | Inventprise Inc. | 2025-10-09 |
| A Clinical Study to Evaluate the Safety, Tolerability and Efficacy of BBM-A101 in the Treatment of Knee Osteoarthritis. (NCT07198555) | Belief BioMed (Beijing) Co., Ltd | 2025-10-09 |
| A Study of DS3610a in Participants With Advanced Solid Tumor (NCT07159126) | Daiichi Sankyo | 2025-10-09 |
| Study About Whether Atirmociclib/PF-07220060 Proportionally Increases Exposure as Dose Increases in Healthy Participants (NCT07215078) | Pfizer | 2025-10-08 |
| Phase I/ II Trial Combining PD-1 Inhibition and Neoadjuvant Proton or Photon Radiation Therapy in Recurrent Head and Neck Squamous Cell Carcinoma (NCT07213934) | University of Cincinnati | 2025-10-08 |
| The Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics Study of SHR-3045 in Healthy Subjects (NCT07200596) | Guangdong Hengrui Pharmaceutical Co., Ltd | 2025-10-08 |
| A First-in-Human Single and Multiple Ascending Dose Study of MT-201 (NCT07219368) | Mirador Therapeutics, Inc. | 2025-10-08 |
| A Research Study of a Potential New Medicine (NNC4005-0001) for Liver Disease in Adult Participants With Increased Body Weight and Liver Fat (NCT07214870) | Novo Nordisk A/S | 2025-10-08 |
| A Study of V118E in Healthy Participants (V118E-003) (NCT07168915) | Merck Sharp & Dohme LLC | 2025-10-08 |
| A PHASE I STUDY OF ALPS12 IN PATIENTS WITH EXTENSIVE STAGE SMALL CELL LUNG CANCER (NCT07107490) | Chugai Pharmaceutical | 2025-10-08 |
| A Study to Assess the Adverse Events and How Oral Emraclidine Moves Through the Body of Healthy Elderly Adult Participants (NCT07219030) | AbbVie | 2025-10-08 |
| A Study in Healthy People to Test How Itraconazole Influences the Amount of BI 3031185 in the Blood (NCT07211425) | Boehringer Ingelheim | 2025-10-08 |
| Gene Modified Immune Cells After Conditioning Regimen for the Treatment of Stage IIIC or IV Melanoma or Metastatic Solid Tumors (NCT04119024) | Anusha Kalbasi | 2025-10-07 |
| Drug-drug Interaction Study of Vorasidenib With Bupropion, Repaglinide, Flurbiprofen, Omeprazole, Midazolam, and Rosuvastatin in Healthy Adult Participants (NCT07235748) | Institut de Recherches Internationales Servier (I.R.I.S.) | 2025-10-07 |
| Evaluating Bioequivalence of a Fixed Dose Combination Versus Tablets of Bempedoic Acid / Ezetimibe and Rosuvastatin (NCT07201545) | Daiichi Sankyo | 2025-10-07 |
| Study Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor Pathway Inhibitors in Participants With Metastatic Hormone-sensitive Prostate Cancer (NCT07140900) | Amgen | 2025-10-07 |
| Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of PN-881 in Healthy Subjects. (NCT07153146) | Protagonist Therapeutics, Inc. | 2025-10-07 |
| BHV-7000 Responsive Neurostimulation System (RNS) Study (NCT07125261) | Yale University | 2025-10-07 |
| A Study to Evaluate the Effect of GDC-4198 Alone and in Combination With Giredestrant Versus Abemaciclib and Giredestrant in Participants With Locally Advanced or Metastatic Estrogen Receptor-Positive (ER+), Human Epidermal Growth Factor Receptor-Negative (HER2-) Breast Cancer (NCT07100106) | Genentech, Inc. | 2025-10-07 |
| A Study of CTD402 in T-ALL/LBL Patients (NCT07070219) | Imviva Bio | 2025-10-07 |
| A Study to Determine the Recommended Dose and Schedule, and Evaluate the Safety and Preliminary Efficacy of Mezigdomide in Combination With Elranatamab in Participants With Relapsed and/or Refractory Multiple Myeloma (NCT06988488) | Celgene | 2025-10-07 |
| A Trial to Compare What the Body Does to Selatogrel and the Effect of Selatogrel in Japanese and Caucasian Healthy Participants (NCT07133191) | Viatris Innovation GmbH | 2025-10-07 |
| MOv19-BBz CAR T Cells in FRa+ Cancers (NCT07116057) | University of Pennsylvania | 2025-10-07 |
| Safety Study of MucoCept-CVN (NCT07181486) | Craig Cohen, MD, MPH | 2025-10-06 |
| A Study Comparing LTG-001 SDD Formulation To LTG-001 Crystalline Immediate Release Tablets In Healthy Participants (NCT07341152) | Latigo Biotherapeutics | 2025-10-06 |
| Study of LFD-200 in Healthy Adults and Adults With Moderate to Severe Rheumatoid Arthritis (NCT07207954) | Lifordi Immunotherapeutics, Inc. | 2025-10-06 |
| A Phase 1 Study of GTX-B001 in Healthy Subjects and Patients With Chronic Inducible Urticaria (NCT07181369) | Granular Therapeutics Limited | 2025-10-06 |
| A First-in-Human Phase 1 Safety and Biodistribution of [177Lu]Lu-ABY-271 in Subjects With HER2-positive Metastatic Breast Cancer (NCT07081555) | Affibody | 2025-10-06 |
| Safety and Efficacy of Injectable Klotho Plasmid Gene Therapy in Humans (NCT07216781) | Minicircle | 2025-10-06 |
| Testing for Safety and Colorectal Cancer Preventive Effects of ONC201 (NCT05630794) | National Cancer Institute (NCI) | 2025-10-06 |
| A Study Testing an Improved Dose of UM171 to Help Make Cord Blood Transplants More Effective and Safe. (NCT07301866) | Ciusss de L'Est de l'Île de Montréal | 2025-10-06 |
| VB19055 Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Study in a Healthy Chinese Population (NCT07254481) | Zhejiang Yangli Pharmaceutical Technology Co., Ltd. | 2025-10-05 |
| A Study to Learn If the Study Medicine Called PF-08049820 Changes How the Body Processes the Other Study Medicines Called Oral Contraceptives, Midazolam, and Dabigatran in Healthy Adult Female Participants (NCT07190430) | Pfizer | 2025-10-03 |
| Pharmacokinetic Interaction Trial of Clofutriben With Midazolam and Prednisolone (NCT07226635) | Sparrow Pharmaceuticals | 2025-10-03 |
| The DART DELIVER-02 Study (NCT07217379) | University of North Carolina, Chapel Hill | 2025-10-02 |
| A Study of DS5361b in Participants With Advanced Solid Tumors (NCT07182591) | Daiichi Sankyo | 2025-10-02 |
| BEACON-1: Study of AVZO-103 as a Single Agent and in Combination Therapy in Patients With Locally Advanced or Metastatic Urothelial Cancer or Other Solid Tumors (AVZO-103-1001) (NCT07193511) | Avenzo Therapeutics, Inc. | 2025-10-02 |
| Clinical Trial of Avasopasem in Patients With Metastatic Hormone Receptor Positive Breast Cancer With Progression on a CDK 4/6 Inhibitor and Hormonal Therapy (NCT07137871) | The University of Texas Health Science Center at San Antonio | 2025-10-02 |
| A Study of Avoralstat In Participants With Diabetic Macular Edema (NCT07228559) | BioCryst Pharmaceuticals | 2025-10-02 |
| CMVIG Prophylaxis in Belatacept Conversion Kidney Transplant Recipients (NCT07096453) | University of Minnesota | 2025-10-02 |
| Study to Evaluate the TUBE Device Ability to Treat Unruptured, Wide-neck or Fusiform Aneurysms (NCT07079956) | NVMedTech | 2025-10-01 |
| In Situ Injection of Anti-angiogenics in Patients With Brain Arteriovenous Malformations Not Eligible for Exclusion Treatment (NCT07075757) | Assistance Publique - Hôpitaux de Paris | 2025-10-01 |
| HEM-iSMART-B: Dasatinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies (NCT05751044) | Princess Maxima Center for Pediatric Oncology | 2025-10-01 |
| Serum Collection Study for Assay Development (NCT07205289) | GPN Vaccines | 2025-10-01 |
| FTT PET/CT in Pancreatic Neuroendocrine Tumors (NCT07114939) | Abramson Cancer Center at Penn Medicine | 2025-10-01 |
| FL118 for Treating Patients With Advanced Pancreatic Ductal Adenocarcinoma (NCT06206876) | Roswell Park Cancer Institute | 2025-10-01 |
| Propolis-Based Solution Application in Extraction Socket Healing (NCT07665814) | Saint-Joseph University | 2025-10-01 |
| A Clinical Study of BT02 in Patients With Relapsed or Refractory Hematologic Malignancies (NCT07107204) | Biotroy Therapeutics | 2025-10-01 |
| A First in Human Single Ascending Dose (SAD) Study of ATI-1013 in Healthy Smokers (NCT07215923) | Antidote Therapeutics, Inc | 2025-10-01 |
| A Study to Investigate the Pharmacokinetics of Tirabrutinib in Participants With Mild, Moderate, and Severe Hepatic Impairment Compared to Healthy Participants (NCT07198087) | Ono Pharmaceutical Co., Ltd. | 2025-10-01 |
| IFx-Hu2.0 As An Adjunctive Therapy To Pembrolizumab In Advanced Or Metastatic Merkel Cell Carcinoma (MCC) (NCT06940440) | TuHURA Biosciences, Inc. | 2025-10-01 |
| Study to Evaluate Safety, Tolerability, and Pharmacokinetics of Amisodin in Healthy Adult Subjects With Amyotrophic Lateral Sclerosis (NCT07221240) | PRG Science & Technology Co., Ltd. | 2025-10-01 |
| BOTOX Injection Technique for LUTS Due to BPH (NCT07645456) | Benha University | 2025-10-01 |
| Study of LW231 in Participants With Chronic Hepatitis B (NCT07179575) | Shanghai Longwood Biopharmaceuticals Co., Ltd. | 2025-10-01 |
| A Randomized Study on Pemphigus Treatment With Humanized CD38 Antibody CM313. (NCT06663943) | Chao Ji | 2025-10-01 |
| HEM-iSMART-C: Ruxolitinib + Venetoclax + Dexamethasone + Cyclophosphamide and Cytarabine in Pediatric Patients With Relapsed or Refractory Hematological Malignancies (NCT05745714) | Princess Maxima Center for Pediatric Oncology | 2025-10-01 |
| Phase I/II Clinical Study to Evaluate the Safety, Tolerability, and Efficacy of GC310 Injection in Patients With Wilson's Disease (WD) (NCT07173933) | GeneCradle Inc | 2025-10-01 |
| Study of AZD0516 as Monotherapy and in Combination in Participants With Metastatic Prostate Cancer (NCT07181161) | AstraZeneca | 2025-10-01 |
| Effect of RECK in Posterior Spinal Fusion (NCT06447194) | University of Maryland, Baltimore | 2025-10-01 |
| PSMA Therapy and Immunotherapy in Kidney Cancer (NCT06361810) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2025-10-01 |
| Luspatercept for the Treatment of Anemia Following Allogeneic Hematopoietic Stem Cell Transplantation(Allo-HSCT) (NCT07362095) | Zhujiang Hospital | 2025-10-01 |
| Laser Interstitial Thermal Therapy (LITT) and Lomustine (CCNU) for Recurrent Glioblastoma (NCT07145112) | University of California, Davis | 2025-10-01 |
| OM336 in Seropositive Autoimmune Diseases (NCT07229144) | Lakefront Biotherapeutics West LLC | 2025-10-01 |
| A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Sjogren's Disease (NCT07041099) | Cullinan Therapeutics Inc. | 2025-10-01 |
| A Safety and Feasibility Trial Protocol of Metformin in Infants After Perinatal Brain Injury (NCT06429007) | Boston Children's Hospital | 2025-10-01 |
| Clinical Study of mTOR Inhibitor as a Treatment for Grey Hair (Canities) (NCT07166354) | Applied Biology, Inc. | 2025-10-01 |
| Ribociclib for HR-positive HER2-negative Metastatic Breast Cancer (NCT07164976) | Nagoya City University | 2025-10-01 |
| Clinical Trial Phase I/IIa to Evaluate the Safety and Immunogenicity of StreptInCor (NCT07078357) | University of Sao Paulo General Hospital | 2025-10-01 |
| Safety and Efficacy of Leucine-Restricted Diet in Gastric Cancer (NCT07488312) | Qilu Hospital of Shandong University | 2025-10-01 |
| Title Fractioned CO2 Laser in the Treatment of Chronic Phase Peyronie's Disease (NCT07177833) | Ottawa Hospital Research Institute | 2025-10-01 |
| Safety of Mulberry Leaf Extract Capsule on Blood Glucose Control in Healthy Volunteer (NCT07532135) | Chulalongkorn University | 2025-10-01 |
| Penfluridol for Relapsed/Refractory Small Cell Cancers (NCT07206563) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2025-10-01 |
| The Prospective Improved Vitamin D Study for Inflammatory Bowel Disease Patients (NCT07177157) | Terry Ponich | 2025-10-01 |
| A Phase 1 Study of 68Ga-R11228 and 177Lu-R11228 in Breast Cancer (NCT07121244) | Radionetics Oncology | 2025-10-01 |
| Human Induced Neural Stem Cell-derived Exosomes for Treating Acute Ischemic Stroke (NCT07143786) | Xuanwu Hospital, Beijing | 2025-10-01 |
| Personalized KXV01 TCR Lentinvivo Injection as the Therapy for Advanced Solid Tumors (NCT07196579) | TCRx Therapeutics Co.Ltd | 2025-10-01 |
| Ketamine Assisted Psychotherapy for Treating Comorbid Chronic Pain and PTSD (NCT07009158) | Queen's University | 2025-10-01 |
| Safety and Immunogenicity Study of SCB-1019T in Children (NCT06666179) | Clover Biopharmaceuticals AUS Pty | 2025-10-01 |
| Preliminary Clinical Study of the Effectiveness and Safety of Ocular Surface Microbiota Transplantation in the Treatment of Dry Eye Disease (NCT07298811) | Second Affiliated Hospital of Nanchang University | 2025-10-01 |