| Bioequivalence and Drug - Drug Interaction Study of Metformin/Gliclazide in Healthy Participants (NCT03467945) | Merck KGaA, Darmstadt, Germany | 2018-02-16 |
| Safety, Pharmacokinetics and Pharmacodynamics of the Two Esomeprazole Formulations (NCT03372850) | Hanmi Pharmaceutical Company Limited | 2018-02-15 |
| A Study of ACE-2494 in Healthy Subjects (NCT03478319) | Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ USA | 2018-02-15 |
| BDB001-101: Clinical Study of BDB001 as a Mono-therapy or in Combination With Pembrolizumab (NCT03486301) | Eikon Therapeutics | 2018-02-15 |
| CAB-AXL-ADC Safety and Efficacy Study in Adult and Adolescent Patients With Sarcoma (NCT03425279) | BioAtla, Inc. | 2018-02-15 |
| IMX-110 in Patients With Advanced Solid Tumors (NCT03382340) | Immix Biopharma Australia Pty Ltd | 2018-02-15 |
| A Study of Experimental Medication BMS-986036 Given to Healthy Participants (NCT03445208) | Bristol-Myers Squibb | 2018-02-14 |
| Toxicity & Pharmacokinetics of 2 & 3-weekly Docetaxel in Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (NCT03343977) | Peng Wang, MD PhD | 2018-02-14 |
| Pegcetacoplan (APL-2) in Neovascular AMD (NCT03465709) | Apellis Pharmaceuticals, Inc. | 2018-02-14 |
| Phase 1 Study of HLX10, a Monoclonal Antibody Targeting Programmed Death-1 (PD-1) in Patients With Advanced Solid Tumors (NCT03468751) | Henlix, Inc | 2018-02-14 |
| A Phase 1 Food Effect Study of Azilsartan (TAK-536) Pediatric Formulation (NCT03434977) | Takeda | 2018-02-14 |
| Safety, Tolerability, Pharmacokinetics and Effects on Transcranial Magnetic Stimulation of Oral Doses of XEN1101 (NCT03468725) | Xenon Pharmaceuticals Inc. | 2018-02-13 |
| A Study to Evaluate the Safety and Efficacy of Ipatasertib in Combination With Atezolizumab and Paclitaxel or Nab-Paclitaxel in Participants With Locally Advanced or Metastatic Triple-Negative Breast Cancer (NCT03800836) | Hoffmann-La Roche | 2018-02-13 |
| Study of Ramucirumab, Trastuzumab and Paclitaxel in Patients With HER2-positive Recurrent/Metastatic Gastric Cancer (HER-RAM Study) (NCT04888663) | Yonsei University | 2018-02-13 |
| Gene Transfer for Sickle Cell Disease (NCT03282656) | David Williams | 2018-02-13 |
| 2ccPA Study in Patients With Symptomatic Knee Osteoarthritis (NCT04229394) | Orient Europharma Co., Ltd. | 2018-02-13 |
| A Study to Evaluate the Effect of Heat Application on the Delivery Profile of Corplex™ Donepezil Transdermal Delivery System (TDS) (NCT03438604) | Corium, Inc. | 2018-02-13 |
| Drug Drug Interaction Study for EYP001 With Entecavir (NCT03469583) | Enyo Pharma | 2018-02-12 |
| A Study of BMS-986253 in Combination With Nivolumab or Nivolumab Plus Ipilimumab in Advanced Cancers (NCT03400332) | Bristol-Myers Squibb | 2018-02-12 |
| Anticoagulation Therapy After Splenectomy in Cirrhosis Patient (NCT04397289) | First Affiliated Hospital Xi'an Jiaotong University | 2018-02-12 |
| Renal Impairment Study (NCT03402438) | Bayer | 2018-02-12 |
| A Pharmacokinetic Trial of Naproxen Sodium and Diphenhydramine Hydrochloride Soft Capsules Versus Naproxen Sodium and Diphenhydramine Hydrochloride Tablets in Healthy Adult Subjects (NCT03396250) | Bayer | 2018-02-12 |
| Relationship Between Plasma Concentration of Hydroxyprogesterone Caproate (17-OHPC) and Preterm Birth (NCT03292731) | Steve N. Caritis, MD | 2018-02-12 |
| Pharmacokinetics and Tolerability of Sulthiame (NCT03400189) | Centre Hospitalier Universitaire Vaudois | 2018-02-12 |
| A Safety, Tolerability, Pharmacokinetics and Immunogenicity Trial of Co-administered MERS-CoV Antibodies REGN3048 and REGN3051 (NCT03301090) | National Institute of Allergy and Infectious Diseases (NIAID) | 2018-02-12 |
| Combined Therapy of Nivolumab and Adoptive T Cell Therapy in Metastatic Melanoma Patients (NCT03374839) | Nantes University Hospital | 2018-02-12 |
| Comparative, Pharmacokinetic and Pharmacodynamic Study of Subcutaneous Injections of INTP5 of Intas Pharmaceuticals Ltd., India Against Neulasta of Amgen Inc., USA in Healthy, Adult Human Subjects. (NCT04014062) | Intas Pharmaceuticals, Ltd. | 2018-02-12 |
| Pharmacokinetics of GLPG3067 in Male Subjects With Cystic Fibrosis. (NCT03589313) | Lakefront Biotherapeutics NV | 2018-02-12 |
| Pilot Dose Escalation Trial of Stereotactic Body Radiation Therapy (SBRT) in Combination With GC4419 in Pancreatic Cancer (NCT03340974) | Galera Therapeutics, Inc. | 2018-02-12 |
| Effect of Buglossoides Oil on Recent Chronic Non-injurious Hip and Knee Pain (NCT03576625) | Réseau de Santé Vitalité Health Network | 2018-02-10 |
| Specialized Food Plan Based on Individual Physiological Comprehensive Body Assessments Accompanied With Cellular Repair Therapy to Decrease Inflammation Cognitively Impaired Patients (NCT03630419) | Perseverance Research Center, LLC | 2018-02-10 |
| Study to Assess the Safety, Tolerability and Immune Response Following Vaccination With Immunose™ FLU in Older Adults (NCT03437304) | Eurocine Vaccines AB | 2018-02-09 |
| Study to Compare a Dose of Telotristat Etiprate in Subjects With Renal Impairment With Matched Subjects With Normal Renal Function (NCT03442725) | Ipsen | 2018-02-09 |
| A Study to Evaluate the Relative Oral Bioavailability of Seltorexant (JNJ-42847922) After Administration of 3 Different Formulations in Healthy Participants Under Fasted and Semi-fasted Conditions (NCT03438461) | Janssen Research & Development, LLC | 2018-02-09 |
| Safety, Tolerability and Pharmacokinetics of PUR1900 (Itraconazole Powder) in Healthy Volunteers and Adults With Asthma (NCT03479411) | Pulmatrix Inc. | 2018-02-09 |
| Venetoclax, Ibrutinib, Prednisone, Obinutuzumab, and Revlimid (ViPOR) in Relapsed/Refractory B-cell Lymphoma (NCT03223610) | National Cancer Institute (NCI) | 2018-02-09 |
| A Crossover Study to Assess the Effect of Intravenous Infusion of Piperacillin/Tazobactam on the Pharmacokinetics of Orally Administered Lumicitabine (JNJ-64041575) in Healthy Adult Participants (NCT03441529) | Janssen Research & Development, LLC | 2018-02-09 |
| A Study to Assess the Safety, Tolerability, and Pharmacokinetics of E2730 in Healthy Participants (NCT03451890) | Eisai Inc. | 2018-02-09 |
| SBRT With Immunotherapy in Early Stage Non-small Cell Lung Cancer: Tolerability and Lung Effects (NCT03383302) | Royal Marsden NHS Foundation Trust | 2018-02-08 |
| A Study In Healthy Male Volunteers Designed To Investigate How A Radiolabelled Medicine Is Broken Down And Removed From The Body (NCT03495934) | Helsinn Healthcare SA | 2018-02-08 |
| A Study of Single Intravitreal Injection HB002.1M in Subjects With Neovascular Age-Related Macular Degeneration (NCT03387566) | Huabo Biopharm Co., Ltd. | 2018-02-08 |
| Testing a New Chemotherapy Drug, KRT-232 (AMG-232) in Combination With Decitabine and Venetoclax in Patients With Acute Myeloid Leukemia (NCT03041688) | National Cancer Institute (NCI) | 2018-02-08 |
| Safety and Tolerability of an Antibody Against Zika Virus (Tyzivumab) in Humans (NCT03443830) | Tychan Pte Ltd. | 2018-02-08 |
| Fecal Microbiota Transplantation (FMT) for MDRO UTI (NCT03367910) | Washington University School of Medicine | 2018-02-08 |
| A Study of the Pharmacokinetics, Pharmacodynamics, and Safety of Opicapone in Subjects With Parkinson's Disease Taking Levodopa. (NCT03496870) | Neurocrine Biosciences | 2018-02-08 |
| Guadecitabine and Durvalumab in Treating Patients With Advanced Liver, Pancreatic, Bile Duct, or Gallbladder Cancer (NCT03257761) | University of Southern California | 2018-02-07 |
| A Study of Experimental Medication BMS-986278 Given to Healthy Participants (NCT03429933) | Bristol-Myers Squibb | 2018-02-07 |
| A Trial of Pembrolizumab and Metformin Versus Pembrolizumab Alone in Advanced Melanoma (NCT03311308) | Yana Najjar | 2018-02-07 |
| A Study to Evaluate the Safety, PK, PD, Immunogenicity of N-Rephasin® SAL200 in Healthy Male Volunteers (NCT03446053) | Intron Biotechnology, Inc. | 2018-02-07 |
| Effect of Systemic Inflammation on Emotion and Cognition in Patients With Mood Disorder - A Vaccine Study (NCT03523767) | The University of Texas Health Science Center, Houston | 2018-02-07 |
| A Phase 1, Single Ascending Dose, Randomized, Double-Blind, Placebo and Positive Controlled Study to Evaluate the Cardiovascular Effect of Tetrodotoxin in Healthy Adult Subjects (NCT04083833) | Wex Pharmaceuticals Inc. | 2018-02-07 |
| A First In Human Study to Assess CiVi007 in Subjects With an Elevated LDL-Cholesterol Level (NCT03427710) | Civi Biopharma, Inc. | 2018-02-07 |
| Clinical Study of a Personalized Neoantigen Cancer Vaccine in Treating Patients With Advanced Malignant Tumor (NCT03662815) | Sir Run Run Shaw Hospital | 2018-02-07 |
| AZD9150 Plus Durvalumab Alone or in Combination With Chemotherapy in Patients With Advanced, Solid Tumours and in Patients With Non-Small-Cell Lung Cancer (NCT03421353) | AstraZeneca | 2018-02-07 |
| Mavoglurant in Alcohol Drinking (NCT03327792) | Yale University | 2018-02-07 |
| Autologous Dendritic Cells, Metronomic Cyclophosphamide and Checkpoint Blockade in Children With Relapsed HGG (NCT03879512) | Wuerzburg University Hospital | 2018-02-07 |
| Daratumumab, Ixazomib, and Dexamethasone in AL Amyloidosis (NCT03283917) | M.D. Anderson Cancer Center | 2018-02-07 |
| Oral Propanolol for Surgically Inaccessible Cavernous Malformations (NCT03523650) | University of Virginia | 2018-02-07 |
| Study to Evaluate Safety, Immunogenicity and Efficacy of PfSPZ Vaccine in HIV Negative and HIV Positive Tanzanian Adults (NCT03420053) | Sanaria Inc. | 2018-02-07 |
| Study to Evaluate the Pharmacokinetics of Lemborexant (E2006) and Its Metabolites in Subjects With Normal Renal Function or With Severe Renal Impairment (NCT03443063) | Eisai Inc. | 2018-02-07 |
| A Study Evaluating Enzalutamide Pharmacokinetics and Pharmacodynamics, and Related Changes After Drug Switch (NCT03778047) | Hinova Pharmaceuticals Inc. | 2018-02-07 |
| Panitumumab-IRDye800 in Patients With Pancreatic Cancer Undergoing Surgery (NCT03384238) | George Poultsides | 2018-02-07 |
| Bioequivalence Study Between SKF101804 Cefixime 200 Milligram (mg)/5 Milliliter (mL) Suspension Versus Cefixime 200 mg/5 mL Suspension Reference Product in Healthy Adult Subjects Under Fasting Conditions (NCT03408392) | GlaxoSmithKline | 2018-02-06 |
| Tolerance and Pharmacokinetics of SHR1459 in Patients With Recurrent Replased/Refractory Mature B Cell Neoplasmstumor (NCT03664297) | Jiangsu HengRui Medicine Co., Ltd. | 2018-02-06 |
| Olaparib and Ramucirumab in Treating Patients With Metastatic or Locally Recurrent Gastric or Gastroesophageal Junction Cancer That Cannot Be Removed by Surgery (NCT03008278) | National Cancer Institute (NCI) | 2018-02-06 |
| A Study to Compare the Pharmacokinetics (PK) of Single Subcutaneous (SC) Injections of Vedolizumab Administered in Prefilled Syringe (PFS) Versus (vs) Prefilled Syringe in Needle Safety Device (PFS+NSD) in Healthy Participants (NCT03949621) | Takeda | 2018-02-06 |
| A Study of Rucaparib in Japanese Patients With a Previously-treated Solid Tumor (NCT03499444) | pharmaand GmbH | 2018-02-06 |
| A Safety, PK and Efficacy Study of CC-92480 Monotherapy and in Combination With Dexamethasone in Subjects With Relapsed and Refractory Multiple Myeloma (RRMM) (NCT03374085) | Celgene | 2018-02-06 |
| ROCKIF Trial: Re-sensitization of Carboplatin-resistant Ovarian Cancer With Kinase Inhibition of FAK (NCT03287271) | Michael McHale | 2018-02-06 |
| v4 Study Evaluating the Safety, Tolerability and Preliminary Pharmacokinetics and Pharmacodynamics of MYK-491 (NCT03447990) | Bristol-Myers Squibb | 2018-02-06 |
| Effect of BIA 5-1058 400 mg on the Steady State Pharmacokinetics of Bosentan (NCT04991207) | Bial - Portela C S.A. | 2018-02-06 |
| Intelligent Virtual Reality Therapy System and Testing Its Clinical Efficacy (NCT04620447) | University College of Medical Sciences, India | 2018-02-05 |
| Bioavailability Study of MGL-3196 Tablets Compared to Capsules (NCT03413124) | Madrigal Pharmaceuticals, Inc. | 2018-02-05 |
| Safety, Efficacy of FFP From Healthy Donors to Ameliorate Frailty and Enhance Immune Function in Older Individuals (NCT03458429) | Dipnarine Maharaj | 2018-02-05 |
| Phase 1 Study of AlphaMedix™ in Adult Subjects With SSTR (+) NET (NCT03466216) | Orano Med LLC | 2018-02-05 |
| Study to Assess the Pharmacokinetic Drug-Drug Interactions of Lemborexant When Coadministered With an Oral Contraceptive, Famotidine, or Fluconazole in Healthy Subjects (NCT03451110) | Eisai Inc. | 2018-02-05 |
| Drug Cocktail Interaction Study of St. John's Wort Dry Extract Ze 117 (NCT03482817) | Max Zeller Soehne AG | 2018-02-05 |
| A First-in-human Phase 1 Study of CP1050 (NCT03468413) | Curadim Pharma Co., Ltd. | 2018-02-05 |
| This Study Tests How Different Doses of BI 1291583 Are Taken up in the Body and How Well They Are Tolerated (NCT03414008) | Boehringer Ingelheim | 2018-02-05 |
| A Study to Assess the Bioavailability of Different Formulations of AZD5718 and the Food Effect on the Selected Formulation of AZD5718 in Healthy Volunteers (NCT03420092) | AstraZeneca | 2018-02-05 |
| Open-Label Study of RVT-501 Topical Ointment in Pediatric Patients With Atopic Dermatitis (NCT03415282) | Dermavant Sciences GmbH | 2018-02-05 |
| A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of a Single Dose of SRP-5051 (Vesleteplirsen) in Patients With Duchenne Muscular Dystrophy (DMD) (NCT03375255) | Sarepta Therapeutics, Inc. | 2018-02-05 |
| First Research Study to Compare a Possible New Medicine NNC9204-1513 to the Medicine Glucagon, in Healthy People. (NCT03444467) | Novo Nordisk A/S | 2018-02-05 |
| Recombinant Interleukin-15 in Combination With Checkpoint Inhibitors Nivolumab and Ipilimumab in People With Refractory Cancers (NCT03388632) | National Cancer Institute (NCI) | 2018-02-05 |
| A Study of E7130 in Participants With Solid Tumors (NCT03444701) | Eisai Co., Ltd. | 2018-02-05 |
| PK/PD, Safety and Tolerability of PHP-201 Topical Eye Drop in Korean and Japanese Healthy Subjects (NCT03586908) | pH Pharma | 2018-02-04 |
| Trametinib and Pembrolizumab in Treating Patients With Recurrent Non-small Cell Lung Cancer That Is Metastatic, Unresectable, or Locally Advanced (NCT03225664) | M.D. Anderson Cancer Center | 2018-02-03 |
| The Use of Allogenic Platelet Rich Plasma for the Treatment of Diabetic Foot Ulcer (NCT02972528) | Hanan Jafar | 2018-02-03 |
| A Study to Evaluate the Safety, Tolerability and Plasma PK of a Single Oral Dose of Zoliflodacin in Healthy Male and Female Volunteers (NCT03404167) | National Institute of Allergy and Infectious Diseases (NIAID) | 2018-02-02 |
| Phase I/II Study of Nivolumab and Ipilimumab Combined With Nintedanib in Non Small Cell Lung Cancer (NCT03377023) | H. Lee Moffitt Cancer Center and Research Institute | 2018-02-02 |
| Haploidentical Transplantation With Pre-Transplant Immunosuppressive Therapy for Patients With Sickle Cell Disease (NCT03279094) | City of Hope Medical Center | 2018-02-02 |
| A Study to Evaluate the Effect of Ustekinumab on Cytochrome P450 Enzyme Activities Following Induction and Maintenance Dosing in Participants With Active Crohn's Disease or Ulcerative Colitis (NCT03358706) | Janssen Research & Development, LLC | 2018-02-02 |
| Maternal Hyperoxygenation in Congenital Heart Disease (NCT03136835) | The Hospital for Sick Children | 2018-02-02 |
| Open-label Study to Evaluate Safety, Tolerability and PK of BHV-0223 in ALS (NCT03520517) | Biohaven Pharmaceuticals, Inc. | 2018-02-02 |
| Pharmacokinetics and Safety of Vilaprisan in Renal Impairment (NCT03411980) | Bayer | 2018-02-02 |
| Unripe Banana Peel Powder and Lemongrass Oil in Chronic Ulcer (NCT04963829) | Universidade do Vale do Sapucai | 2018-02-02 |
| Pharyngeal Electrical Stimulation in Amyotrophic Lateral Sclerosis (NCT03481348) | University of Ulm | 2018-02-01 |
| Copanlisib and Gemcitabine in Relapsed/Refractory PTCL (NCT03052933) | Chonnam National University Hospital | 2018-02-01 |
| CM Delivered PST in LLD Pilot (NCT03408821) | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2018-02-01 |
| QUILT-3.044: NANT Non-small Cell Lung Cancer (NSCLC) Vaccine: Combination Immunotherapy in Subjects With NSCLC Who Have Progressed After Treatment With PD-1/PD-L1 Inhibitors (NCT03169738) | ImmunityBio, Inc. | 2018-02-01 |