| Single-dose Pharmacokinetics of BMS-986177 in Participants With Hepatic Impairment Compared to Healthy Participants (NCT02982707) | Bristol-Myers Squibb | 2018-03-01 |
| Inhibition of VAP-1 by Caffeine in Healthy Human Volunteers Study (NCT02098785) | University of Birmingham | 2018-03-01 |
| Mesothelin-Targeted Immunotoxin LMB-100 in Combination With SEL-110 in Subjects With Malignant Pleural or Peritoneal Mesothelioma (NCT03436732) | National Cancer Institute (NCI) | 2018-02-28 |
| Demethylated Drug in the Treatment of Nasopharyngeal Carcinoma (NCT03701451) | Wei Jiang | 2018-02-28 |
| A Study to Evaluate the Effect of Food on the Pharmacokinetics (PK) of TAK-659 in Participants With Advanced Solid Tumor (NCT03359733) | Calithera Biosciences, Inc | 2018-02-28 |
| Drug-Drug Interaction (DDI) Study for TD-9855 (NCT03432793) | Theravance Biopharma | 2018-02-28 |
| Evaluating the Safety and Serum Concentrations of a Human Monoclonal Antibody, VRC-HIVMAB075-00-AB (VRC07-523LS), Administered in Multiple Doses and Routes to Healthy, HIV-uninfected Adults (NCT03387150) | National Institute of Allergy and Infectious Diseases (NIAID) | 2018-02-28 |
| Selective β2-AR Antagonism in Asthma (NCT07272135) | Trio Medicines Ltd. | 2018-02-28 |
| A Study of the Effect of Epinephrine on Platelet Reactivity in Subjects Treated With Ticagrelor (NCT03441412) | Vastra Gotaland Region | 2018-02-28 |
| HSV-tk and XRT and Chemotherapy for Newly Diagnosed GBM (NCT03603405) | The Methodist Hospital Research Institute | 2018-02-28 |
| Therapeutic Equivalence Study of Generic Brinzolamide vs Azopt (NCT03896633) | Bausch & Lomb Incorporated | 2018-02-28 |
| Effect of BIA 5-1058 on the Steady State Pharmacokinetics of Treprostinil (NCT04675944) | Bial - Portela C S.A. | 2018-02-28 |
| Safety and Efficacy of 21 Gy, 23 Gy and 25 Gy for High Dose Rate (HDR) Prostate Brachytherapy (NCT03424850) | Washington University School of Medicine | 2018-02-27 |
| DAY101 In Gliomas and Other Tumors (NCT03429803) | Karen D. Wright, MD | 2018-02-27 |
| MGD009/MGA012 Combination in Relapsed/Refractory Cancer (NCT03406949) | MacroGenics | 2018-02-27 |
| GRAVITAS-119: Itacitinib in Combination With Calcineurin Inhibitor-Based Interventions for the Prophylaxis of Graft-Versus Host Disease (NCT03320642) | Incyte Corporation | 2018-02-27 |
| Follow up Protocol to the Phase I/II Study of OPN-305 in Second-line or Third-line Lower Lower Risk Myelodysplastic Syndrome (NCT03337451) | Opsona Therapeutics Ltd. | 2018-02-27 |
| GMCI, Nivolumab, and Radiation Therapy in Treating Patients With Newly Diagnosed High-Grade Gliomas (NCT03576612) | Candel Therapeutics, Inc. | 2018-02-27 |
| QUILT-2.022 NANT-008 in Combination w/ 5-fluorouracil, Bevacizumab, Leucovorin & Oxaliplatin in Subjects With Pancreatic Cancer (NCT03127124) | NantPharma, LLC | 2018-02-27 |
| An Efficacy and Safety Study of shRNA-modified CD34+ Cells in HIV-infected Patients. (NCT03517631) | Shanghai Public Health Clinical Center | 2018-02-27 |
| A Study of BAX 888 in Male Adults With Severe Hemophilia A (NCT03370172) | Baxalta now part of Shire | 2018-02-27 |
| Safety and Efficacy of SGN-LIV1A Plus Pembrolizumab for Patients With Locally-Advanced or Metastatic Triple-Negative Breast Cancer (NCT03310957) | Seagen Inc. | 2018-02-27 |
| A Study to Evaluate the Safety of K-755 in Healthy Volunteers (NCT03414294) | Kowa Company, Ltd. | 2018-02-27 |
| Rucaparib Hepatic Impairment Study in Patients With a Solid Tumor (NCT03521037) | pharmaand GmbH | 2018-02-27 |
| Clazakizumab in Highly-HLA Sensitized Patients Awaiting Renal Transplant (NCT03380962) | Stanley Jordan, MD | 2018-02-27 |
| Psilocybin - Induced Neuroplasticity in the Treatment of Major Depressive Disorder (NCT03554174) | Yale University | 2018-02-27 |
| Multiple-ascending Dose Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD9977 in Healthy Male Subjects (NCT03435276) | AstraZeneca | 2018-02-27 |
| Safety and Tolerability Evaluation Study of BVAC-B in Patients With HER2/Neu(Human Epithelial Growth Factor Receptor 2) Positive Gastric Cancer After Failure to Standard Care (NCT03425773) | Cellid Co., Ltd. | 2018-02-26 |
| Effect of Pexidartinib on the Way the Body Processes CYP3A4 and CYP2C9 Substrates (Pharmacokinetics) (NCT03291288) | Daiichi Sankyo | 2018-02-26 |
| Study to Evaluate the PK of Single and Optional Multiple Dosing Regimens of MR Formulations of PCS499 Compared to Trental® Administered to Healthy Subjects (NCT03836222) | Processa Pharmaceuticals | 2018-02-26 |
| Phase I/II Trial of Lentiviral Gene Transfer for SCID-X1 With Low Dose Targeted Busulfan Conditioning (NCT03311503) | David Williams | 2018-02-26 |
| A Study of AK002 in Patients With Atopic Keratoconjunctivitis, Vernal Keratoconjunctivitis, and Perennial Allergic Conjunctivitis (NCT03379311) | Allakos Inc. | 2018-02-26 |
| Investigation of Cocaine Addiction Using mGluR5 PET and fMRI (NCT03471182) | Yale University | 2018-02-26 |
| AMG0103 in Subjects With Chronic Discogenic Lumbar Back Pain (NCT03263611) | AnGes, Inc. | 2018-02-26 |
| To Assess the Relative Bioavailability (BA) of TRIUMEQ® and Dolutegravir and Lamivudine (DTG/3TC) Pediatric Dispersible Tablet Formulations in Healthy Volunteers (NCT03441984) | ViiV Healthcare | 2018-02-26 |
| A Study to Investigate the Safety, Tolerability and Pharmacokinetics of ABY-039 (NCT03502954) | Affibody | 2018-02-26 |
| A Study to Evaluate the Pharmacokinetics of ACT-541468 in Subjects With Mild, Moderate, and Severe Hepatic Impairment (NCT03713242) | Idorsia Pharmaceuticals Ltd. | 2018-02-26 |
| Comparative Immunogenicity Study of Multiple Doses of Proposed Pegfilgrastim Biosimilar, INTP5 of Intas Pharmaceuticals Ltd., India Against Neulasta of Amgen Inc., USA in Healthy, Adult Human Subjects. (NCT04015232) | Intas Pharmaceuticals, Ltd. | 2018-02-26 |
| Safety Study of LLF580 in Obese Volunteers (NCT03466203) | Novartis Pharmaceuticals | 2018-02-26 |
| Study to Evaluate the Safety and Preliminary Efficacy of IDCT, a Treatment for Symptomatic Lumbar Intervertebral Disc Degeneration (NCT03347708) | DiscGenics, Inc. | 2018-02-26 |
| Randomized, Placebo-controlled, Observer-blinded Phase 1 Safety and Immunogenicity Study of Inactivated Zika Virus Vaccine Candidate in Healthy Adults (NCT03425149) | Valneva Austria GmbH | 2018-02-24 |
| To Explore the Safety and Efficacy of Hypidone Hydrochloride Tablets in Treatment of Patients With MDD (NCT03404466) | Zhejiang Huahai Pharmaceutical Co., Ltd. | 2018-02-24 |
| Study to Find a Safe and Effective Dose of SKI-G-801 in the Treatment of Patients With Acute Myeloid Leukemia (AML) (NCT03564288) | Oscotec Inc. | 2018-02-23 |
| HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant (NCT03326921) | Fred Hutchinson Cancer Center | 2018-02-23 |
| Effect of BIA 5-1058 400 mg on Warfarin Pharmacokinetics (NCT04994119) | Bial - Portela C S.A. | 2018-02-23 |
| A Food Effect Study in Healthy Volunteers With Belzutifan (PT2977, MK-6482) Tablets (NCT03445169) | Peloton Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 2018-02-23 |
| A Study Comparing Oxymetazoline 1% Cream to RHOFADE (NCT05148689) | Sun Pharmaceutical Industries, Inc. | 2018-02-23 |
| A Pilot Study on Intermittent Ibrutinib in Patients With Advanced-phase Chronic Lymphocytic Leukemia (CLL) (NCT04771507) | Jeanette Lundin | 2018-02-23 |
| Dose Escalation Study of the Pharmacodynamics, Pharmacokinetics, Safety, and Immunogenicity of BCD-132 in Patients With Relapsing-Remitting Multiple Sclerosis (NCT03551275) | Biocad | 2018-02-22 |
| A Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ESN364 in Healthy Japanese Male and Pre- and Post-menopausal Female Subjects (NCT03436849) | Astellas Pharma Inc | 2018-02-22 |
| A Pilot Study to Compare the Pharmacokinetics (PK) of Single Subcutaneous (SC) Injections of Vedolizumab Administered in Prefilled Syringe (PFS) Versus (vs) Prefilled Syringe in Autoinjector (PFS+AI) in Healthy Participants (NCT03961295) | Takeda | 2018-02-22 |
| Epacadostat (INCB24360) in Combination With Sirolimus in Advanced Malignancy (NCT03217669) | Chao Huang | 2018-02-22 |
| Study of ACTR087 in Combination With SEA-BCMA in Subjects With Relapsed or Refractory Multiple Myeloma (NCT03266692) | Cogent Biosciences, Inc. | 2018-02-22 |
| Therapeutic Vaccine Plus PD-1 Knockout in Prostate Cancer Treatment (NCT03525652) | The First Affiliated Hospital of Guangdong Pharmaceutical University | 2018-02-22 |
| Multiple-Dose, Dose-Escalation Study to Evaluate the Safety/Tolerability and Pharmacokinetics of FP-045 (NCT03686930) | Foresee Pharmaceuticals Co., Ltd. | 2018-02-22 |
| The Antibiotic Rifampin to Reduce High Levels of Blood and Urine Calcium in IIH (NCT03384121) | The Hospital for Sick Children | 2018-02-22 |
| Study of STRO-001, an Anti-CD74 Antibody Drug Conjugate, in Patients With Advanced B-Cell Malignancies (NCT03424603) | Sutro Biopharma, Inc. | 2018-02-22 |
| Combination Therapy With Nivolumab and PD-L1/IDO Peptide Vaccine to Patients With Metastatic Melanoma (NCT03047928) | Inge Marie Svane | 2018-02-22 |
| Study to Evaluate the Respiratory Safety of Lemborexant in Adult and Elderly Healthy Subjects and Adult and Elderly Subjects With Mild Obstructive Sleep Apnea (NCT03471871) | Eisai Inc. | 2018-02-21 |
| Clazakizumab for Chronic and Active Antibody Mediated Rejection Post-Kidney Transplant (NCT03380377) | Stanley Jordan, MD | 2018-02-21 |
| Safety, Tolerability and Pharmacokinetics of an Anti-PD-1 Monoclonal Antibody in Subjects With Advanced Malignancies (NCT03474640) | TopAlliance Biosciences | 2018-02-21 |
| Copper 64Cu-DOTA-Daratumumab Positron Emission Tomography in Diagnosing Patients With Relapsed Multiple Myeloma (NCT03311828) | City of Hope Medical Center | 2018-02-21 |
| TIL-ACT After NMA Chemo with IL-2 and Nivo Rescue in Metastatic Melanoma (mMEL) (NCT03475134) | Centre Hospitalier Universitaire Vaudois | 2018-02-21 |
| Initial Investigation of [18F]P16-129 in Alzheimer's Disease Patients and Healthy Volunteers (NCT03902548) | Five Eleven Pharma, Inc. | 2018-02-21 |
| A Pilot Study to Compare the Pharmacokinetics (PK) of Single Subcutaneous (SC) Injections of Vedolizumab Administered in Prefilled Syringe (PFS) Versus (vs) Prefilled Syringe in Needle Safety Device (PFS+NSD) in Healthy Participants (NCT03948581) | Takeda | 2018-02-21 |
| Use of Analgesic Treatment to Reduce Signs of Pain in Patients With Disorders of Consciousness. (NCT04330547) | University of Liege | 2018-02-21 |
| Open Label, Study Of Efficacy and Safety Of AVR-RD-01 for Treatment-Naive Subjects With Classic Fabry Disease (NCT03454893) | AVROBIO | 2018-02-21 |
| CT-P13 (Infliximab) Subcutaneous Administration by Pre-filled Syringe and Auto-injector in Healthy Subjects (NCT03446976) | Celltrion | 2018-02-21 |
| Cabozantinib as a Targeted Strategy to Reverse Carfilzomib Resistance in Refractory Multiple Myeloma (NCT03201250) | University of Nebraska | 2018-02-21 |
| A Study to Evaluate the Safety of PRV-300 in Adult Subjects With Moderately to Severely Active Ulcerative Colitis (NCT03849599) | Provention Bio, Inc. | 2018-02-21 |
| Lomecel-B Delivered During Stage II Surgery for Hypoplastic Left Heart Syndrome (ELPIS) (NCT03525418) | Longeveron Inc. | 2018-02-21 |
| Isatuximab in Combination With Cemiplimab in Relapsed/Refractory Multiple Myeloma (RRMM) Patients (NCT03194867) | Sanofi | 2018-02-21 |
| Safety of Single Intravenous Administration of S95010 in Human Healthy Volunteers (NCT03494712) | Institut de Recherches Internationales Servier | 2018-02-21 |
| IGF-MTX Conjugate in the Treatment of Myelodysplastic Syndrome (NCT03175978) | IGF Oncology, LLC | 2018-02-21 |
| Contrast-Enhanced Ultrasound for Kidney Transplant (NCT02911714) | University of Utah | 2018-02-21 |
| First-In-Human PainCart Study for STR-324 (NCT03430232) | Stragen France | 2018-02-20 |
| Study of T Cells Targeting CD19/BCMA (CART-19/BCMA) for High Risk Multiple Myeloma Followed With Auto-HSCT (NCT03455972) | The First Affiliated Hospital of Soochow University | 2018-02-20 |
| Pharmacokinetic and Safety Study of Niraparib With Normal or Moderate Hepatic Impairment Patients (NCT03359850) | Tesaro, Inc. | 2018-02-20 |
| A Safety Study of SGN-CD48A in Patients With Multiple Myeloma (NCT03379584) | Seagen Inc. | 2018-02-20 |
| Challenge Infection of Healthy Adult Volunteers With RSV A2 (NCT03388645) | National Institute of Allergy and Infectious Diseases (NIAID) | 2018-02-20 |
| Study to Evaluate Exicorilant (CORT125281) in Combination With Enzalutamide in Patients With Metastatic Castration-Resistant Prostate Cancer (NCT03437941) | Corcept Therapeutics | 2018-02-20 |
| A Study of KZR-616 in Patients With SLE With and Without Lupus Nephritis (NCT03393013) | Kezar Life Sciences, Inc. | 2018-02-20 |
| Phase Ib Study of Stereotactic Body Radiotherapy (SBRT) in Oligometastatic Non-small Lung Cancer (NSCLC) With Dual Immune Checkpoint Inhibition (NCT03275597) | University of Wisconsin, Madison | 2018-02-20 |
| Bioavailability and Bioequivalence Between Two Active Pharmaceutical Ingredient (API) Sources of Opicapone (OPC) (NCT04265027) | Bial - Portela C S.A. | 2018-02-20 |
| Single-Dose Bioequivalence Study Comparing Two 2 mg Nicotine Lozenges (NCT03432273) | Fertin Pharma A/S | 2018-02-19 |
| A Study of Chronocort® Versus Cortef ® in Healthy Adult Male Subjects (NCT03343327) | Neurocrine UK Limited | 2018-02-19 |
| Safety, Tolerability, and Pharmacokinetics of Single and Multiple Ascending Oral Doses of XEN901 (NCT03467100) | Xenon Pharmaceuticals Inc. | 2018-02-19 |
| Personalized Booster Feedback After Alcohol Health Education (NCT03440476) | Abby Braitman | 2018-02-19 |
| Pharmacokinetic Study Comparing Tiotropium Easyhaler and Spiriva Handihaler (NCT03400241) | Orion Corporation, Orion Pharma | 2018-02-19 |
| Neratinib and Paclitaxel With or Without Pertuzumab and Trastuzumab Before Combination Chemotherapy in Treating Patients With Metastatic or Locally Advanced Breast Cancer (NCT03101748) | M.D. Anderson Cancer Center | 2018-02-19 |
| Intravesical Ty21a for the Treatment of Patients With Non-muscle-invasive Bladder Cancer (NMIBC) (NCT03421236) | Patrice Jichlinski | 2018-02-18 |
| Study of Boserolimab (MK-5890) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Adults With Advanced Solid Tumors (MK-5890-001) (NCT03396445) | Merck Sharp & Dohme LLC | 2018-02-18 |
| A Study of LY900014 in Japanese Participants With Type 1 Diabetes Mellitus (NCT03407118) | Eli Lilly and Company | 2018-02-17 |
| A Bioequivalence Study of the Lu AA21004 20 mg and 2×10 mg Tablets (NCT03437564) | Takeda | 2018-02-16 |
| A Study of TAK-659 in Combination With Venetoclax for Adult Participants With Previously Treated Non-Hodgkin Lymphoma (NCT03357627) | Calithera Biosciences, Inc | 2018-02-16 |
| A Bioequivalence Study of Losartan Potassium Tablets (Containing Losartan Potassium 100 mg) in Normal, Healthy, Adults Under Fasting Conditions (NCT03459911) | Pharmtechnology LLC | 2018-02-16 |
| A Study to Test the Safety, Pharmacokinetics, and Pharmacodynamics of Single Ascending Intravenous Doses of UCB0107 in Healthy Male Subjects (NCT03464227) | UCB Biopharma S.P.R.L. | 2018-02-16 |
| Safety and Efficacy of Pembrolizumab (MK-3475) Plus Binimetinib Alone or Pembrolizumab Plus Chemotherapy With or Without Binimetinib in Metastatic Colorectal Cancer (mCRC) Participants (MK-3475-651/KEYNOTE-651) (NCT03374254) | Merck Sharp & Dohme LLC | 2018-02-16 |
| Safety of Autologous Cord Blood Cells in HLHS Patients During Norwood Heart Surgery (NCT03431480) | Murdoch Childrens Research Institute | 2018-02-16 |
| Study Comparing Intravenous and Subcutaneous Infudopa With Intestinal Duodopa in Patients With Parkinson's Disease (NCT03419806) | Vastra Gotaland Region | 2018-02-16 |