| Phase 1 Bioavailability Study of MELT-100 (Midazolam and Ketamine Sublingual) and IV Midazolam or Ketamine (NCT04485702) | Melt Pharmaceuticals | 2020-07-20 |
| Modified Immune Cells (AFM13-NK) and A Monoclonal Antibody (AFM13) in Treating Patients With Recurrent or Refractory CD30 Positive Hodgkin or Non-Hodgkin Lymphomas (NCT04074746) | M.D. Anderson Cancer Center | 2020-07-18 |
| To Evaluate the Safety, Tolerability and Pharmacokinetics of CT-P59 in Healthy Subjects (NCT04525079) | Celltrion | 2020-07-18 |
| Donor Bone Marrow Derived Mesenchymal Stem Cells in Controlling Heart Failure in Patients With Cardiomyopathy Caused by Anthracyclines (NCT02962661) | M.D. Anderson Cancer Center | 2020-07-18 |
| A Phase I Clinical Study of JS004 in Subjects With Recurrent/Refractory Malignant Lymphoma of China (NCT04477772) | Shanghai Junshi Bioscience Co., Ltd. | 2020-07-17 |
| A Study of TQ05105 Tablets in Subjects With Hemophagocytic Lymphohistiocytosis（HLH） (NCT04326348) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2020-07-17 |
| Evaluation of AZD8154 Concentrations in Blood (NCT04480879) | AstraZeneca | 2020-07-17 |
| Testing the Addition of an Anti-cancer Drug, Copanlisib, to the Usual Immunotherapy (Nivolumab With or Without Ipilimumab) in Patients With Advanced Solid Cancers That Have Changes in the Following Genes: PIK3CA and PTEN (NCT04317105) | National Cancer Institute (NCI) | 2020-07-17 |
| To Evaluate the Safety, Tolerability, and Pharmacokinetics Profiles of TG-1000 in Healthy Volunteers, and the Food Effect on Pharmacokinetics of Single Oral Dose of TG-1000 in Healthy Volunteers. (NCT04495322) | TaiGen Biotechnology Co., Ltd. | 2020-07-17 |
| Study of Feasibility and Safety of UCD19 Chimeric Antigen Receptor (CAR) T Cells in Adult Subjects With Relapsed/Refractory (R/R) B-Cell Non-Hodgkin's Lymphoma (B-NHL) (NCT04240808) | University of Colorado, Denver | 2020-07-17 |
| A Phase 1b Trial to Evaluate Safety and Effect of SAR443122 on Immune System in Severe COVID-19 (NCT04469621) | Sanofi | 2020-07-17 |
| Study of Single and Multiple Ascending Doses of PF-07059013 in Healthy Adult Participants (NCT04323124) | Pfizer | 2020-07-17 |
| First-in-human Study of CCW702 in Patients With Metastatic Castration Resistant Prostate Cancer (NCT04077021) | Calibr, a division of Scripps Research | 2020-07-17 |
| Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Malignancies (NCT04561362) | BicycleTx Limited | 2020-07-17 |
| A Phase I Study of SHR1459 in Healthy Subjects (NCT04455100) | Jiangsu HengRui Medicine Co., Ltd. | 2020-07-17 |
| A Study to Evaluate the Impact of Acid-reducing Agents on the Pharmacokinetics (PK) of AMG 510 in Healthy Participants (NCT05599828) | Amgen | 2020-07-17 |
| Single-dose AME Study With [14C]AR882 in Healthy Male Subjects (NCT04508426) | Arthrosi Therapeutics | 2020-07-16 |
| A Study Evaluating Safety, Pharmacokinetics, Pharmacodynamics, And Clinical Activity Of RO7119929 (TLR7 Agonist) In Participants With Unresectable Advanced Or Metastatic Hepatocellular Carcinoma, Biliary Tract Cancer, Or Solid Tumors With Hepatic Metastases (NCT04338685) | Hoffmann-La Roche | 2020-07-16 |
| LIGHT-PSMA-CART in Treating Patients With Castrate-Resistant Prostate Cancer (NCT04053062) | Bioray Laboratories | 2020-07-16 |
| Pulmonary Suffusion in Controlling Minimal Residual Disease in Patients With Sarcoma or Colorectal Metastases (NCT03965234) | Roswell Park Cancer Institute | 2020-07-16 |
| Hepatic Impairment, Cholestatic Liver Disease, & NASH with Advanced Fibrosis & Normal Hepatic Function (NCT04469920) | Zydus Therapeutics Inc. | 2020-07-16 |
| A Study of Oral Seltorexant as an add-on Medication to an Antidepressant on On-road Driving Performance in Participants With Major Depressive Disorder (NCT04451187) | Janssen Research & Development, LLC | 2020-07-16 |
| Interstitial Brachytherapy for the Treatment of Unresectable/Unablatable Kidney Cancer (NCT04473781) | Jonsson Comprehensive Cancer Center | 2020-07-16 |
| A Study of Tividenofusp Alfa (DNL310) in Pediatric Participants With Hunter Syndrome (NCT04251026) | Denali Therapeutics Inc. | 2020-07-16 |
| A Study of Ad26.COV2.S in Adults (COVID-19) (NCT04436276) | Janssen Vaccines & Prevention B.V. | 2020-07-15 |
| Whole-Virion Inactivated SARS-CoV-2 Vaccine (BBV152) for COVID-19 in Healthy Volunteers (NCT04471519) | Bharat Biotech International Limited | 2020-07-15 |
| Drug-drug Interaction Study Between HEC74647PA Capsule and HEC110114 Tablets in Healthy Subjects (NCT04232514) | Sunshine Lake Pharma Co., Ltd. | 2020-07-15 |
| Contrast-Enhanced Ultrasound Diagnosis of Acute Appendicitis (NCT03295656) | Boston Children's Hospital | 2020-07-15 |
| A Study on the Safety of GEN1044 (DuoBody®-CD3x5T4) in Patients With Malignant Solid Tumors (NCT04424641) | Genmab | 2020-07-15 |
| Evaluation of GLR2007 for Advanced Solid Tumors (NCT04444427) | Gan and Lee Pharmaceuticals, USA | 2020-07-15 |
| HS-201, an HSP90 Inhibitor-linked Verteporfin for Detection of Solid Malignancies (NCT03906643) | Herbert Lyerly | 2020-07-15 |
| Safety, Tolerability and Immunogenicity of INO-4800 Followed by Electroporation in Healthy Volunteers for COVID19 (NCT04447781) | International Vaccine Institute | 2020-07-15 |
| Trial of Indomethacin in Chronic Pancreatitis (NCT04207060) | Mayo Clinic | 2020-07-15 |
| PET/MRI, 18F-FDG PET/CT and Whole Body MRI in Finding Extramedullary Myeloid Leukemia in Patients With Newly Diagnosed Acute Myeloid Leukemia (NCT02390635) | M.D. Anderson Cancer Center | 2020-07-15 |
| LY3214996 in Patients With AML Who Are Not Candidates for Standard Therapy (NCT04081259) | Dana-Farber Cancer Institute | 2020-07-15 |
| An Imaging Agent (I-124 M5A) in Detecting CEA-Positive Liver Metastases in Patients With Colorectal Cancer (NCT03993327) | City of Hope Medical Center | 2020-07-15 |
| A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect of RO6953958 in Healthy Participants (NCT04475848) | Hoffmann-La Roche | 2020-07-15 |
| Neoantigen-based Personalized DNA Vaccine in Patients With Newly Diagnosed, Unmethylated Glioblastoma (NCT04015700) | Washington University School of Medicine | 2020-07-14 |
| TTX-080 HLA-G Antagonist in Subjects With Advanced Cancers (NCT04485013) | Tizona Therapeutics, Inc | 2020-07-14 |
| A Study of the Efficacy and Safety of Camrelizumab Plus Radiotherapy for Patients With Early Triple-Negative Breast (NCT04481763) | Jiangxi Provincial Cancer Hospital | 2020-07-14 |
| A Study of (14C)-JNJ-73841937 (Lazertinib) in Healthy Male Participants (NCT04410081) | Janssen Research & Development, LLC | 2020-07-14 |
| Study of BMS-986315 Alone and in Combination With Nivolumab or Cetuximab in Participants With Advanced Solid Tumors (NCT04349267) | Bristol-Myers Squibb | 2020-07-14 |
| Clinical Trial to Evaluate the Safety and Pharmacokinetic Characteristics in Healthy Volunteers (NCT04478097) | Chong Kun Dang Pharmaceutical | 2020-07-14 |
| Efficacy of Iodine Complex Against COVID-19 Patients (NCT04473261) | Sohaib Ashraf | 2020-07-14 |
| A Phase I/II Study of ASTX660 in Patients With Relapsed or Refractory T-cell Lymphoma (NCT04362007) | Otsuka Pharmaceutical Co., Ltd. | 2020-07-14 |
| A Study of JAB-3312 in Adult Patients With Advanced Solid Tumors in China (NCT04121286) | Allist Pharmaceuticals, Inc. | 2020-07-14 |
| A Study of DF6002 Alone and in Combination With Nivolumab (NCT04423029) | Dragonfly Therapeutics | 2020-07-13 |
| Assessing the Immunogenicity of pING-hHER3FL (NCT03832855) | Herbert Lyerly | 2020-07-13 |
| A Single Arm, Phase Ib/II Trial of Single Agent Pacritinib in Patients With 1q21.3 Amplified Solid Tumors Enriching for Interleukin-1 Receptor-associated Kinase 1 Pathway Activation (PAIR) (NCT04520269) | National University Hospital, Singapore | 2020-07-13 |
| First-in-Human, Phase 1b/2a Trial of a Multipeptide Therapeutic Vaccine in Patients With Progressive Glioblastoma (NCT04116658) | Enterome | 2020-07-13 |
| A Study in Healthy Men to Test How BI 1358894 is Taken up in the Body and How Food Influences the Amount of BI 1358894 in the Blood (NCT04426851) | Boehringer Ingelheim | 2020-07-13 |
| B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults (NCT04483778) | Seattle Children's Hospital | 2020-07-13 |
| Potential Influence of Esomeprazole on the Pharmacokinetics of Pritelivir (NCT05513625) | AiCuris Anti-infective Cures AG | 2020-07-13 |
| Safety and Biomarker Response to (+)-Epicatechin in Becker Muscular Dystrophy (NCT04386304) | Epirium Bio Inc. | 2020-07-13 |
| Bintrafusp Alfa (M7824) and PDS01ADC Alone and in Combination With Stereotactic Body Radiation Therapy (SBRT) in Adults With Metastatic Non-Prostate Genitourinary Malignancies (NCT04235777) | National Cancer Institute (NCI) | 2020-07-13 |
| Safety, Tolerability, and Pharmacokinetics Study of Human Monoclonal Antibody BRII-198 (NCT04479644) | Brii Biosciences Limited | 2020-07-13 |
| HDM201 and Midostaurin (HDMM) in Relapsed/Refractory AML With FLT3mut and TP53wt. (NCT04496999) | Insel Gruppe AG, University Hospital Bern | 2020-07-13 |
| PDS01ADC Monotherapy and in Combination With M7824 in Advanced Kaposi Sarcoma (NCT04303117) | National Cancer Institute (NCI) | 2020-07-13 |
| Study of Adjuvant Immunotherapy With EVX-02 and Anti-PD-1 (NCT04455503) | Evaxion Biotech A/S | 2020-07-13 |
| Single and Multiple Dose Safety, Tolerability, PK and Food Effect Study of HEC585 in Healthy Male and Female Subjects (NCT04512170) | Sunshine Lake Pharma Co., Ltd. | 2020-07-13 |
| A Study on the Safety, Tolerability and Immune Response of SARS-CoV-2 Sclamp (COVID-19) Vaccine in Healthy Adults (NCT04495933) | The University of Queensland | 2020-07-13 |
| A Study to Investigate the Effect of Food on the Pharmacokinetics of HSG4112 (NCT04733001) | Glaceum | 2020-07-12 |
| Safety, Tolerability, and Pharmacokinetics Study of Human Monoclonal Antibody BRII-196 (NCT04479631) | Brii Biosciences Limited | 2020-07-12 |
| Study in Healthy Subjects to Examine the Safety and Tolerability of ACT-1004-1239 Given as Multiple, Gradually Increasing Doses and to Examine the Effects of ACT-1004-1239 on the Body and the Way the Body Takes up, Distributes, and Gets Rid of ACT-1004-1239 (NCT04286750) | Idorsia Pharmaceuticals Ltd. | 2020-07-11 |
| A Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of AG-946 in Healthy Volunteers and in Participants With Sickle Cell Disease (NCT04536792) | Agios Pharmaceuticals, Inc. | 2020-07-10 |
| Safety and Immunogenicity Study of an Inactivated SARS-CoV-2 Vaccine for Preventing Against COVID-19 in People Aged ⩾60 Years (NCT04470609) | Institute of Medical Biology, Chinese Academy of Medical Sciences | 2020-07-10 |
| A Study of TAK-102 in Adult With Previously-Treated Solid Tumors (NCT04405778) | Takeda | 2020-07-10 |
| The Pharmacokinetics/Pharmacodynamics and Safety/Tolerability of Evogliptin in Hemodialysis Patients (NCT04195919) | Dong-A ST Co., Ltd. | 2020-07-10 |
| Processed Amniotic Fluid (PAF) Drops After Photorefractive Keratectomy (PRK) (NCT04281004) | University of Utah | 2020-07-10 |
| Safety, Tolerability and Immunogenicinity of a Coronavirus-Like Particle COVID-19 Vaccine in Adults Aged 18-55 Years. (NCT04450004) | Medicago | 2020-07-10 |
| Study to Evaluate Safety, Tolerability, and Pharmacokinetics of XNW4107 Alone or in Combination With Imipenem/Cilastatin (NCT04482569) | Evopoint Biosciences Inc. | 2020-07-10 |
| CD19-targeted CAR T Cells （JWCAR029） for Primary Refractory Diffuse Large B Cell Lymphoma (NCT04812691) | Shanghai Ming Ju Biotechnology Co., Ltd. | 2020-07-10 |
| Tasquinimod for the Treatment of Relapsed or Refractory Myeloma (NCT04405167) | University of Pennsylvania | 2020-07-10 |
| Immuno-Oncology Drugs Elotuzumab, Anti-LAG-3 and Anti-TIGIT (NCT04150965) | Multiple Myeloma Research Consortium | 2020-07-10 |
| A Study to Assess the Levels in Blood Plasma of BMS-986278 in Healthy Participants Following Administration of Tablets, With or Without Food, and in the Presence of an Antacid (Esomeprazole) (NCT04468815) | Bristol-Myers Squibb | 2020-07-10 |
| A Study of CC-90010 in Combination With Temozolomide With or Without Radiation Therapy in Participants With Newly Diagnosed Glioblastoma (NCT04324840) | Celgene | 2020-07-10 |
| First in Human Study of M6223 (NCT04457778) | EMD Serono Research & Development Institute, Inc. | 2020-07-10 |
| Safety, Tolerability and Pharmacokinetics of Oral NX-13 in Healthy Adults Male and Female Volunteers (NCT04458805) | Landos Biopharma Inc. | 2020-07-10 |
| Safety and Immunogenicity of a Live-attenuated Vaccine Against Respiratory Syncytial Virus in Elderly Volunteers (NCT04295070) | Codagenix, Inc | 2020-07-10 |
| A Study of JNJ-70218902 in Participants With Advanced Stage Solid Tumors (NCT04397276) | Janssen Research & Development, LLC | 2020-07-10 |
| Microtransplantation and Checkpoint Blockade Immunotherapy for Relapsed or Refractory B Cell Lymphomas (NCT03920631) | Ahmed Galal, MD | 2020-07-10 |
| Single and Multiple Ascending Dose Study to Assess the Safety, Tolerability and PK of ONO-2910 in Japanese and Caucasian Subjects (NCT04504760) | Ono Pharmaceutical Co., Ltd. | 2020-07-10 |
| IN10018 Monotherapy or in Combination With Docetaxel in Gastric or GEJ Adenocarcinoma (NCT05327231) | InxMed (Shanghai) Co., Ltd. | 2020-07-09 |
| A Phase 1 Study to Evaluate the Pharmacokinetics of Setmelanotide in Subjects With Varying Degrees of Renal Impairment (NCT04348175) | Rhythm Pharmaceuticals, Inc. | 2020-07-09 |
| A Study to Measure Energy Expenditure and Food Intake in Participants With Obesity Using Tirzepatide (NCT04081337) | Eli Lilly and Company | 2020-07-09 |
| CD4CAR for CD4+ Leukemia and Lymphoma (NCT03829540) | Huda Salman | 2020-07-09 |
| Study to Assess Absolute Bioavailability of TAK-935 (OV935) and to Characterize Mass Balance, Pharmacokinetics, Metabolism, and Excretion of [14C]TAK-935 (OV935) in Healthy Male Participants (NCT04992442) | Takeda | 2020-07-09 |
| Infliximab or Vedolizumab in Treating Immune Checkpoint Inhibitor-Related Colitis in Patients With Genitourinary Cancer or Melanoma (NCT04407247) | M.D. Anderson Cancer Center | 2020-07-09 |
| A Study Evaluating The Safety, Efficacy and Pharmacokinetics Of Ipatasertib In Combination With Atezolizumab And Docetaxel In Metastatic Castration-Resistant Prostate Cancer (mCRPC). (NCT04404140) | Hoffmann-La Roche | 2020-07-09 |
| Surufatinib DDI With a PPI and a CYP3A Inducer (NCT04510649) | Hutchison Medipharma Limited | 2020-07-09 |
| A Study of TL-895 With Standard Available Treatment Versus Standard Available Treatment for the Treatment of COVID-19 in Patients With Cancer (NCT04419623) | Telios Pharma, Inc. | 2020-07-09 |
| Preoperative Lenvatinib Plus Pembrolizumab in Early-Stage Triple-Negative Breast Cancer (TNBC) (NCT04427293) | University of Illinois at Chicago | 2020-07-09 |
| A Study to Assess the Safety, Pharmacokinetics and Anti Tumor Activity of UCB6114 Administered Intravenously to Participants With Advanced Solid Tumors (NCT04393298) | UCB Biopharma SRL | 2020-07-09 |
| Chimeric Antigen Receptor T-cells for The Treatment of AML Expressing CLL-1 Antigen (NCT04219163) | Baylor College of Medicine | 2020-07-09 |
| A Phase I Trial of CCT303-406 in Patients With Relapsed or Refractory HER2 Positive Solid Tumors (NCT04511871) | Shanghai PerHum Therapeutics Co., Ltd. | 2020-07-09 |
| A Study of ICP-022 in Patients With Systemic Lupus Erythematosus (SLE) (NCT04305197) | Beijing InnoCare Pharma Tech Co., Ltd. | 2020-07-09 |
| Mesenchymal Stem Cells for the Treatment of Various Chronic and Acute Conditions (NCT04684602) | Thomas Advanced Medical LLC | 2020-07-09 |
| Peppermint Oil Pharmacokinetics/Dynamics (NCT04497870) | Baylor College of Medicine | 2020-07-09 |
| The Bioequivalence Study of Umifenovir 200 mg Capsul (ATABAY, Turkey) Under Fasting Conditions (NCT04476719) | Atabay Kimya Sanayi Ticaret A.S. | 2020-07-09 |
| A Study to Assess the Effect of a Strong CYP3A Inhibitor, on Surufatinib in Healthy Subjects (NCT04372407) | Hutchison Medipharma Limited | 2020-07-09 |