| FGFR4 Inhibitor EVER4010001 in Combination With PD-1 Inhibitor Pembrolizumab in Patients With Advanced Solid Tumors (NCT04699643) | EverNov Medicines (Zhuhai Hengqin) Co., Ltd | 2020-07-30 |
| Study to Assess Absolute Bioavailability (ABA) of TAK-906 and to Characterize Mass Balance, Pharmacokinetics (PK), Metabolism, and Excretion of [14C]-TAK-906 in Healthy Male Participants (NCT04454918) | Millennium Pharmaceuticals, Inc. | 2020-07-30 |
| The Pharmacokinetic(PK)/Pharmacodynamics(PD) Study of SHR7280 Tablets in Premenopausal Subjects With Endometriosis. (NCT04417972) | Jiangsu HengRui Medicine Co., Ltd. | 2020-07-30 |
| Memory & Conditioning Under Anesthesia (NCT04062123) | Keith M Vogt | 2020-07-30 |
| Safety, Tolerability, and Pharmacokinetics of XXB750 in Healthy Participants (NCT06558097) | Novartis Pharmaceuticals | 2020-07-29 |
| A Study to Test Different Doses of Obrixtamig in Patients With Small Cell Lung Cancer and Other Neuroendocrine Tumours That Are Positive for DLL3 (NCT04429087) | Boehringer Ingelheim | 2020-07-29 |
| Study of GNX102 in Patients With Advanced Solid Tumors (NCT04250597) | GlycoNex, Inc. | 2020-07-29 |
| Safety, Tolerability, and Pharmacokinetics of SAB-176 in Healthy Participants (NCT04471038) | SAb Biotherapeutics, Inc. | 2020-07-29 |
| Relative Levels of BMS-986036 in Blood Plasma in Healthy, Overweight, and Obese Participants Following Subcutaneous Administration Via Auto-injector Versus Pre-filled Syringe (NCT04493567) | Bristol-Myers Squibb | 2020-07-29 |
| A Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Participants With Advanced or Metastatic Solid Tumors With a KRAS G12C Mutation (NCT04449874) | Genentech, Inc. | 2020-07-29 |
| Mesenchymal Stromal Cells for Infants With Congenital Heart Disease (MedCaP) (NCT04236479) | Catherine Bollard | 2020-07-29 |
| A Phase 1, Double-blind, Randomized, Placebo-controlled, Single- and Multiple-dose Escalating Study (NCT05021666) | PegBio Co., Ltd. | 2020-07-29 |
| Study of Cord Blood Derived Mesenchymal Stem Cells for Treatment of Moderate, Severe or Critical Pneumonia (NCT04565665) | M.D. Anderson Cancer Center | 2020-07-29 |
| The Effect of Moderate CYP3A Inducer Rifabutin on the Pharmacokinetics of Zanubrutinib in Healthy Males (NCT04470908) | BeiGene | 2020-07-29 |
| CD123-Directed T-Cell Therapy for Acute Myelogenous Leukemia (CATCHAML) (NCT04318678) | St. Jude Children's Research Hospital | 2020-07-29 |
| Study of Tirzepatide in Healthy Participants (NCT04311424) | Eli Lilly and Company | 2020-07-28 |
| A Study of MIL62 Combined With Orelabrutinib for the Treatment of R/R CD20+B Cell Lymphoma (NCT04304040) | Beijing InnoCare Pharma Tech Co., Ltd. | 2020-07-28 |
| A First-in-human Study of Multiple Doses of BB-1701 in Subjects With Locally Advanced/Metastatic HER2 Expressing Solid Tumors (NCT04257110) | Bliss Biopharmaceutical (Hangzhou) Co., Ltd | 2020-07-28 |
| Phase 1 Clinical Trial to Evaluate the Safety, PK and PD of DA-5207 TDS in Healthy Adults (NCT04479865) | Dong-A ST Co., Ltd. | 2020-07-28 |
| A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect of Oral HRS5091 in Healthy Subjects and Chronic Hepatitis B Patients (NCT04480294) | Jiangsu HengRui Medicine Co., Ltd. | 2020-07-28 |
| Nicotinamide Riboside as an Enhancer of Exercise Therapy in Hypertensive Older Adults (The NEET Trial) (NCT04112043) | University of Florida | 2020-07-28 |
| HYPORT: A Phase I/II Study of Hypofractionated Post-operative Radiation Therapy for Head and Neck Cancer (NCT04403620) | University of Texas Southwestern Medical Center | 2020-07-28 |
| Safety and Immunogenicity of SARS-CoV-2 mRNA Vaccine (BNT162b1) in Chinese Healthy Subjects (NCT04523571) | BioNTech SE | 2020-07-28 |
| A Phase 1 PK Study of Tolperisone in Healthy Subjects (NCT04465266) | Neurana Pharmaceuticals, Inc. | 2020-07-28 |
| Infigratinib Before Surgery for the Treatment of Upper Tract Urothelial Cancer (NCT04228042) | M.D. Anderson Cancer Center | 2020-07-28 |
| ONO-7913 Phase I Study (ONO-7913) (NCT04403308) | Ono Pharmaceutical Co., Ltd. | 2020-07-28 |
| Magrolimab, Azacitidine, and Venetoclax for the Treatment of Acute Myeloid Leukemia (NCT04435691) | M.D. Anderson Cancer Center | 2020-07-28 |
| Study of Ampion for the Treatment of Adult COVID-19 Patients Requiring Oxygen Supplementation (NCT04456452) | Ampio Pharmaceuticals. Inc. | 2020-07-27 |
| A Study of SBT6050 Alone and in Combination With PD-1 Inhibitors in Subjects With Advanced HER2 Expressing Solid Tumors (NCT04460456) | Silverback Therapeutics | 2020-07-27 |
| Study of Combination Therapy With INCMGA00012 (Anti-PD-1), INCAGN02385 (Anti-LAG-3), and INCAGN02390 (Anti-TIM-3) in Participants With Select Advanced Malignancies (NCT04370704) | Incyte Corporation | 2020-07-27 |
| Study Of Single And Multiple Ascending Doses Of PF-07054894 In Healthy Adult Participants (NCT04388878) | Pfizer | 2020-07-27 |
| VNRX-5024 Safety and PK in Healthy Adult Volunteers (NCT04314206) | Basilea Pharmaceutica | 2020-07-27 |
| A Study to Assess the Reversal of the Anticoagulant Effects of Milvexian by 4-Factor Prothrombin Complex Concentrate (4F-PCC) (Part 1) and Recombinant Human Factor VIIa (rFVIIa) (Part 2) in Healthy Participants (NCT04543383) | Janssen Research & Development, LLC | 2020-07-27 |
| Chloroquine Phosphate Prophylactic Use in Health Personnel Exposed to COVID-19 Patients (NCT04443270) | CMN "20 de Noviembre" | 2020-07-27 |
| Efficacy of VIC Regimen in BRAF Mutant Metastatic Colorectal Cancer (NCT04790448) | Sun Yat-sen University | 2020-07-27 |
| Bispecific CD19/CD22 CAR-T for Treatment of Children and Young Adults With r/r B-ALL (NCT04499573) | Federal Research Institute of Pediatric Hematology, Oncology and Immunology | 2020-07-27 |
| Metformin in Dengue With Obesity (NCT04377451) | Oxford University Clinical Research Unit, Vietnam | 2020-07-27 |
| IN10018 in Combination With Standard Chemotherapy in High-grade Serous Epithelial Ovarian Cancer (NCT05551507) | InxMed (Shanghai) Co., Ltd. | 2020-07-27 |
| Study of Welgenaleucel (UWC19) in Patients With Relapsed or Refractory B-cell Lymphoma (NCT04296461) | UWELL Biopharma | 2020-07-27 |
| INCB7839 in Treating Children With Recurrent/Progressive High-Grade Gliomas (NCT04295759) | Pediatric Brain Tumor Consortium | 2020-07-27 |
| A Pharmacokinetic Study of Saroglitazar Magnesium in Subjects with Severe Renal Impairment and Normal Renal Function (NCT04446507) | Zydus Therapeutics Inc. | 2020-07-27 |
| Phase 1/2 Study of AGN-241622 in Healthy Participants and Participants With Presbyopia (NCT04403763) | AbbVie | 2020-07-27 |
| Study of the Safety, Reactogenicity and Immunogenicity of "EpiVacCorona" Vaccine for the Prevention of COVID-19 (NCT04527575) | Federal Budgetary Research Institution State Research Center of Virology and Biotechnology "Vector" | 2020-07-27 |
| A Pharmacokinetic Interaction Study Between Apatinib and Rosuvastatin or Metformin in Solid Tumor Subjects. (NCT04428086) | Jiangsu HengRui Medicine Co., Ltd. | 2020-07-27 |
| Study Assessing the Safety, Tolerability, Pharmacokinetics, and Immunogenicity of Repeated Subcutaneous Doses of Anti-Spike (S) SARS-CoV-2 Monoclonal Antibodies (REGN10933+REGN10987) in Adult Volunteers as Related to COVID-19 (NCT04519437) | Regeneron Pharmaceuticals | 2020-07-26 |
| Safety and Feasibility of Allogenic MSC in the Treatment of COVID-19 (NCT04467047) | Hospital de Clinicas de Porto Alegre | 2020-07-25 |
| An Exploratory Clinical Trial of Autologous Humanized Anti-cluster of Differentiation Antigen 19/20(CD19/CD20) Dual Specific CAR-T Cells Injection (NCT04486872) | First Affiliated Hospital of Zhejiang University | 2020-07-25 |
| First-in-human Single Agent Study of SAR442257 in RRMM and RR-NHL (NCT04401020) | Sanofi | 2020-07-24 |
| A Study of the Cardiac Effects of ALXN1840 in Healthy Adults (NCT04560816) | Alexion Pharmaceuticals, Inc. | 2020-07-24 |
| S-flurbiprofen Bioavailability Trial to Compare a Newly Developed Patch vs. a Marketed Tablet (NCT04505787) | SocraTec R&D GmbH | 2020-07-24 |
| Role of Montelukast in Modulation of Response to Sepsis in Preterm Infants (NCT04474327) | Mansoura University Children Hospital | 2020-07-24 |
| Nitric Oxide Therapy for COVID-19 Patients With Oxygen Requirement (NCT04476992) | Tomsk National Research Medical Center of the Russian Academy of Sciences | 2020-07-24 |
| Regenerative Medicine for COVID-19 and Flu-Elicited ARDS Using Lomecel-B (RECOVER) (NCT04629105) | Longeveron Inc. | 2020-07-24 |
| Safety, Tolerability and Pharmacokinetics of SCTA01, an Anti-SARS-CoV-2 Monoclonal Antibody, in Healthy Chinese Subjects (NCT04483375) | Sinocelltech Ltd. | 2020-07-24 |
| Relative Bioavailability of Two Different Capsule Formulations of Sitravatinib in Healthy Adults (NCT04472650) | BeiGene | 2020-07-23 |
| A Novel Therapeutic Vaccine (EO2401) in Metastatic Adrenocortical Carcinoma, or Malignant Pheochromocytoma/Paraganglioma (NCT04187404) | Enterome | 2020-07-23 |
| Camrelizumab in Combination With Apatinib in Refractory and Relapsed DLBCL (NCT04476459) | Huiqiang Huang | 2020-07-23 |
| Study on the Safety of BAY1817080, How it is Tolerated and the Way the Body Absorbs, Distributes and Gets Rid of the Study Drug in Participants With Impaired Liver Function or Normal Liver Function (NCT04454424) | Bayer | 2020-07-23 |
| BCMA-directed CAR-T Cell Therapy in Adult Patients With Multiple Myeloma (NCT04318327) | Novartis Pharmaceuticals | 2020-07-23 |
| A Clinical Trial to Evaluate the Effect of Nilotinib on the PK/PD of Meformin (NCT04448821) | Hyewon Chung | 2020-07-23 |
| A Phase 1 Study to Evaluate the Effect of Food on Pharmacokinetics of ASTX029 (NCT04466514) | Astex Pharmaceuticals, Inc. | 2020-07-23 |
| A Clinical Study Investigating the Safety, Tolerability, PK and PD of PCO371 in Patients With Hypoparathyroidism (NCT04209179) | Chugai Pharmaceutical | 2020-07-23 |
| Study of RP-3500, Camonsertib, in Advanced Solid Tumors (NCT04497116) | Repare Therapeutics | 2020-07-22 |
| A Study of Dazostinag as Single Agent and Dazostinag in Combination With Pembrolizumab in Adults With Advanced or Metastatic Solid Tumors (NCT04420884) | Takeda | 2020-07-22 |
| A Study to Evaluate the Safety and Pharmacokinetics With MEDI8367 Administered in Healthy Subjects, and in Subjects With Chronic Kidney Disease (NCT04365218) | AstraZeneca | 2020-07-22 |
| A Phase I/IIa Clinical Trial to Assess Feasibility, Safety and Antitumor Activity of Autologous SLAMF7 CAR-T Cells in Multiple Myeloma (NCT04499339) | Wuerzburg University Hospital | 2020-07-22 |
| Novel MRI-Guided Ultrasound Stimulated Microbubble Radiation Treatment for Patients With Chest-wall and Breast Cancer (NCT04431674) | Sunnybrook Health Sciences Centre | 2020-07-22 |
| A Study of Select Drug Combinations in Adult Patients With Advanced/Metastatic BRAF V600 Colorectal Cancer (NCT04294160) | Novartis Pharmaceuticals | 2020-07-22 |
| The Effect of Reduced Liver Function on Selatogrel Pharmacokinetics (NCT04406896) | Viatris Innovation GmbH | 2020-07-22 |
| A Phase 1 Study of GNR-051 in Subjects With Advanced Malignancies (NCT04544748) | AO GENERIUM | 2020-07-22 |
| Study To Characterize Mass Balance, Absolute Bioavailability, Fraction Absorbed And Pharmacokinetics Of 14C PF-06882961 (NCT04495140) | Pfizer | 2020-07-22 |
| Study of the Safety of Therapeutic Treatment With an Immunomodulatory Agent (N-803) in Adults With COVID-19 (NCT04385849) | ImmunityBio, Inc. | 2020-07-22 |
| Study to Assess Safety, Tolerability and Phamacokinetics of KAE609 Administered Intravenously in Healthy Subjects (NCT04321252) | Novartis Pharmaceuticals | 2020-07-22 |
| Azacitidine and Quizartinib for the Treatment of Myelodysplastic Syndrome or Myelodysplastic/Myeloproliferative Neoplasm With FLT3 or CBL Mutations (NCT04493138) | M.D. Anderson Cancer Center | 2020-07-21 |
| Deferoxamine for Sickle Cell Chronic Leg Ulcer Treatment (NCT04058197) | TauTona Group | 2020-07-21 |
| Dose Escalation Trial of CM310 in Patients With Moderate-to-Severe Atopic Dermatitis (AD) (NCT04893941) | Keymed Biosciences Co.Ltd | 2020-07-21 |
| A Study in Healthy Men to Test How Well Different Doses of BI 1569912 Are Tolerated and How Food Influences the Amount of BI 1569912 in the Blood (NCT04445090) | Boehringer Ingelheim | 2020-07-21 |
| A Study to Evaluate the Safety and Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of Melrilimab (GSK3772847) in Healthy Participants (NCT04366349) | GlaxoSmithKline | 2020-07-21 |
| A Study to Assess the Effect of Fluvoxamine and Smoking on Pharmacokinetics ( the Movement of Drugs Within the Body) of AZD4635 in Healthy Volunteers (NCT04478513) | AstraZeneca | 2020-07-21 |
| A Study of Macitentan, in Healthy Japanese Male Participants (NCT04500808) | Janssen Pharmaceutical K.K. | 2020-07-21 |
| Injection Site Pain Comparison of Excipient Solutions (NCT04482725) | Novo Nordisk A/S | 2020-07-20 |
| Evaluation of Safety and Efficiency of Method of Exosome Inhalation in SARS-CoV-2 Associated Pneumonia. (NCT04491240) | State-Financed Health Facility "Samara Regional Medical Center Dinasty" | 2020-07-20 |
| A Study in Healthy Subjects to Investigate the Safety and Tolerability of ACT- 541478 as Well as What ACT-541478 Does to the Body and the Way the Body Takes up, Distributes, and Gets Rid of ACT-541478 (NCT04452006) | Idorsia Pharmaceuticals Ltd. | 2020-07-20 |
| A Study to Evaluate Effects of Proton-pump Inhibitor on Acalabrutinib Capsule When Administered Orally With COCA-COLA in Healthy Participants (NCT04489797) | AstraZeneca | 2020-07-20 |
| Testing the Addition of an Anti-cancer Drug, Triapine, to the Usual Radiation-Based Treatment (Lutetium Lu 177 Dotatate) for Neuroendocrine Tumors (NCT04234568) | National Cancer Institute (NCI) | 2020-07-20 |
| A Drug-drug Interaction Trial to Evaluate the Pharmacokinetics Effect of Rifampicin on Famitinib (NCT04494659) | Jiangsu HengRui Medicine Co., Ltd. | 2020-07-20 |
| Dose Escalation Study to Assess the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of QBS10072S (NCT04430842) | Quadriga Biosciences, Inc. | 2020-07-20 |
| A Study on the Anti-Wrinkle Efficacy Assessment and Safety Evaluation of the Cluster of Autologous Dermal Fibroblast on Bilateral Crow's Feet (NCT04818203) | S.Biomedics Co., Ltd. | 2020-07-20 |
| A Study to Evaluate Drug-drug Interactions Between BR9006-1 and BR9006-2 in Healthy Male Volunteers. (NCT04485585) | Boryung Pharmaceutical Co., Ltd | 2020-07-20 |
| A Study of AL2846 Capsule Combined With Standard Chemotherapy Regimen in Subjects With Advanced Colorectal Cancer (NCT04337879) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2020-07-20 |
| MEN1611 With Cetuximab in Metastatic Colorectal Cancer (C-PRECISE-01) (NCT04495621) | Menarini Group | 2020-07-20 |
| Safety, Tolerability, Pharmacokinetics(PK), Pharmacodynamics(PD) and Food Effect of HRS9950 in Healthy and CHB Subjects (NCT04464733) | Jiangsu HengRui Medicine Co., Ltd. | 2020-07-20 |
| A Phase I Study of QL1604 for Advanced Solid Tumors (NCT05801094) | Qilu Pharmaceutical Co., Ltd. | 2020-07-20 |
| A Study to Assess the Effects of Acid-Reducing Agent(s) on JNJ-64417184 in Healthy Participants (NCT04453189) | Janssen Research & Development, LLC | 2020-07-20 |
| Study to Assess the Effect of Acid-reducing Agent Famotidine on the Drug Levels of BMS-986256 in Healthy Participants (NCT04470778) | Bristol-Myers Squibb | 2020-07-20 |
| An Additional Study of NPC-22 in Healthy Adult Males (NCT04503863) | Nobelpharma | 2020-07-20 |
| Effect of Food on the Pharmacokinetics of ASTX660 in Healthy Volunteers (NCT04479800) | Astex Pharmaceuticals, Inc. | 2020-07-20 |
| Comparison of Plasma Caffeine Concentration After Oral Consumption of Caffeinated Beverages With Varied Bioactive Compounds in Healthy Volunteers (NCT04281758) | PepsiCo Global R&D | 2020-07-20 |
| CIML NK Cell in Head & Neck Cancer (NCT04290546) | Dana-Farber Cancer Institute | 2020-07-20 |
| Impact of Botox Treatment Into the Upper One Third of the Face an Area on Mood and Self -Appearance Satisfaction (NCT04439825) | DeNova Research | 2020-07-20 |