| A Study to Learn About the Medicine (PF-07321332 or Nirmatrelvir/Ritonavir) in Healthy Lactating Women (NCT05441215) | Pfizer | 2022-12-12 |
| Safety and Tolerability of Glyceryl Tribenzoate (GTB) Capsules in Healthy Subjects (NCT05938452) | Forest Hills Lab | 2022-12-12 |
| Study to Evaluate the Safety, Tolerability, and PK of Pacritinib (NCT05552183) | CTI BioPharma | 2022-12-12 |
| First in Human Phase 1 Ascending Dose Study of PanChol in Healthy Volunteers (NCT05657782) | Brigham and Women's Hospital | 2022-12-12 |
| CORONA: A Study Using DeltaRex-G Gene Therapy for Symptomatic COVID-19 (NCT04378244) | Aveni Foundation | 2022-12-12 |
| A Study to Evaluate the Pharmacokinetics of HSK16149 in Subjects With Renal Impairment (NCT05916573) | Haisco Pharmaceutical Group Co., Ltd. | 2022-12-12 |
| CLL-1/CD33 Targeted LCAR-AMDR Cells in Patients With Relapsed or Refractory Acute Myeloid Leukemia (NCT05654779) | Institute of Hematology & Blood Diseases Hospital, China | 2022-12-12 |
| Allogenic CD19-targeting CAR-γδT Cell Therapy in R/R NHL (NCT05554939) | Chinese PLA General Hospital | 2022-12-11 |
| Trial of Immunotherapy With Avelumab and Pepinemab As Second Line For Patients With Metastatic Pancreatic Adenocarcinoma (NCT05102721) | Vaccinex Inc. | 2022-12-10 |
| Safety and Efficacy of Sequential CD19 and CD22 Targeted CAR-T Therapy for Relapsed/Refractory B Cell Lymphoma (NCT05651100) | Kecellitics Biotech Company Ltd | 2022-12-10 |
| Absorption of Antibiotics With High Oral Bioavailability in Short-bowel Syndrome (NCT05302531) | Central Hospital, Nancy, France | 2022-12-09 |
| A Study to Understand the Effect of a Study Medicine Called ARV-471 on Rosuvastatin in Healthy Adults (NCT05652660) | Pfizer | 2022-12-09 |
| A Study of Intraperitoneally Administered AVB-001 in Patients With Serous Adenocarcinoma of the Ovary (NCT05538624) | Avenge Bio, Inc | 2022-12-09 |
| A Study of BMS-986360/CC-90001 Alone and in Combination With Chemotherapy or Nivolumab in Advanced Solid Tumors (NCT05625412) | Bristol-Myers Squibb | 2022-12-09 |
| A Phase I Clinical Study of HLX53 in Advanced/Metastatic Solid Tumors (NCT05394168) | Shanghai Henlius Biotech | 2022-12-09 |
| Study of the Safety and Efficacy of OMS906 in Patients With Paroxysmal Nocturnal Hemoglobinuria (NCT05889299) | Omeros Corporation | 2022-12-09 |
| IN10018+ Standard Chemotherapy (+KN046) in Subjects With Advanced Pancreatic Cancer (NCT05827796) | InxMed (Shanghai) Co., Ltd. | 2022-12-08 |
| NKTR-255 in Combination With CAR-T Cell Therapy for the Treatment of Relapsed or Refractory Large B-cell Lymphoma (NCT05359211) | Fred Hutchinson Cancer Center | 2022-12-08 |
| A Study to Characterize the Safety, Tolerability, and Preliminary Efficacy of CFT1946 as Monotherapy and Combination Therapy in Subjects With BRAF V600 Mutant Solid Tumors (NCT05668585) | C4 Therapeutics, Inc. | 2022-12-08 |
| A Study to Evaluate the Pharmacokinetics and Safety of INCB054707 in Participants With Normal Hepatic Function and Participants With Hepatic Impairment (NCT05624710) | Incyte Corporation | 2022-12-08 |
| MEDI5752 in Japanese Patients With Advanced Solid Tumors. (NCT05685472) | AstraZeneca | 2022-12-08 |
| A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics (PD) of RO7497372 in Participants With Diabetic Macular Edema (DME) (NCT06847854) | Genentech, Inc. | 2022-12-08 |
| Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cell Intravenous Infusion for Osteoporosis (NCT05152381) | The Foundation for Orthopaedics and Regenerative Medicine | 2022-12-08 |
| A Clinical Trial in Healthy Volunteers and Volunteers With Recurrent Genital Herpes to Study the Safety, Tolerability, and Immune Responses After Vaccination With an Investigational Vaccine Designed to Prevent Genital Herpes Lesions (NCT05432583) | BioNTech SE | 2022-12-08 |
| A Study of Universal CD19-Targeted UCAR-NK Cells Combined With HSCT for B Cell Hematologic Malignancies (NCT05654038) | 920th Hospital of Joint Logistics Support Force of People's Liberation Army of China | 2022-12-08 |
| A Study to Evaluate Safety and Pharmacokinetics of ZB002 in Healthy Participants and Participants With Rheumatoid Arthritis (NCT05638854) | Zenas BioPharma (USA), LLC | 2022-12-08 |
| 3BNC117-LS and 10-1074-LS Plus N-803 (bNAb+N-803) (NCT05245292) | Rockefeller University | 2022-12-07 |
| A Trial of Cobicistat and Gemcitabine and Nab-Paclitaxel in Patients with Advanced Stage or Metastatic Pancreatic Ductal Adenocarcinoma (NCT05494866) | German Cancer Research Center | 2022-12-07 |
| GH55 for Advanced Cancers With MAPK Mutations: A Study on Safety and Early Results (NCT06310382) | Suzhou Genhouse Bio Co., Ltd. | 2022-12-07 |
| Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of OC-01 in Adult Chinese With Dry Eye Disease (NCT05576415) | Corxel Pharmaceuticals | 2022-12-07 |
| Safety and Immunogenicity of Recombinant Herpes Zoster Vaccine (CHO Cells) in Healthy Subjects Aged 18 Years and Above (NCT05636436) | MAXVAX Biotechnology Limited Liability Company | 2022-12-07 |
| First in Human Study of 68Ga/64Cu-FAPI-XT117 PET/CT in Patients With Malignant Solid Tumors (NCT05814835) | Chinese PLA General Hospital | 2022-12-07 |
| Rinatabart Sesutecan (Rina-S, PRO1184, GEN1184) for Advanced Solid Tumors (GCT1184-01/ PRO1184-001) (NCT05579366) | Genmab | 2022-12-07 |
| Safety, Tolerability, Pharmacokinetic and Pharmacodynamic of ID120040002 in Healthy Volunteers (NCT05663879) | IlDong Pharmaceutical Co Ltd | 2022-12-07 |
| Berubicin in Adult Patients With Recurrent Glioblastoma Multiforme (WHO Grade IV) (NCT04915404) | WPD Pharmaceuticals Sp. z o.o. | 2022-12-07 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Efficacy and Indications of RP903 (NCT06846099) | Risen (Suzhou) Pharma Tech Co., Ltd. | 2022-12-07 |
| A Phase 1 Trial of PfSPZ Vaccine in Healthy Adults to Determine Safety, Tolerability and Efficacy Against Heterologous CHMI (NCT05604521) | Sanaria Inc. | 2022-12-06 |
| Dosing and Tolerability of Deoxycholic Acid vs. Polidocanol in the Treatment of Neurofibromatosis Type 1 Cutaneous Neurofibromas (NCT06120036) | Massachusetts General Hospital | 2022-12-06 |
| A Single and Multiple Ascending Dose Study of CK-3828136 in Healthy Adult Participants (NCT05662215) | Cytokinetics | 2022-12-06 |
| Phase I Open Label BCG Clinical Trial Assessing TB Drugs and Vaccines (NCT05592223) | Fred Hutchinson Cancer Center | 2022-12-06 |
| Dose Escalation TTHX1114 Ophthalmic Solution (NCT05769920) | Trefoil Therapeutics, Inc. | 2022-12-06 |
| A Safety, Tolerability, and Pharmacokinetics Study of AP303 in Healthy Subjects (NCT05503693) | Alebund Pty Ltd | 2022-12-06 |
| Lifitegrast Eye Drops in Healthy Subjects：Phase I Study (NCT07040826) | Qilu Pharmaceutical Co., Ltd. | 2022-12-06 |
| WTX-330 in Patients With Advanced or Metastatic Solid Tumors or Non-Hodgkin Lymphoma (NCT05678998) | Werewolf Therapeutics, Inc. | 2022-12-06 |
| Dose Escalation Study to Evaluate the Safety and Immunogenicity of the Cholera Conjugate Vaccine in Healthy Adults (NCT05559983) | International Vaccine Institute | 2022-12-05 |
| Safety and Blood Levels After a Single Injection of UPB-101 in Healthy Japanese and Non-Japanese Non-East Asian Adults (NCT05653479) | Upstream Bio Inc. | 2022-12-05 |
| MAD Study of NX210c (NCT05827653) | Axoltis Pharma | 2022-12-05 |
| Study to Evaluate Adverse Events, Change in Disease Activity, and How ABBV-706 Moves Through the Body When Intravenously (IV) Infused Alone or in Combination With IV Infused Budigalimab, Cisplatin, or Carboplatin in Adult Participants With Advanced Solid Tumors (NCT05599984) | AbbVie | 2022-12-05 |
| Neurodegenerative Alzheimer's Disease and Amyotrophic Lateral Sclerosis (NADALS) Basket Trial (NCT05189106) | Massachusetts General Hospital | 2022-12-05 |
| AB1 in Adult Patients with Sickle Cell Disease (SCD) (NCT05261711) | Nirmish Shah | 2022-12-05 |
| A Trial of HRS-7085 Tablet in Healthy Participants With and Without Food Effect. (NCT05638347) | Atridia Pty Ltd. | 2022-12-05 |
| Novel Anti-CD19 Universal CAR-T Cells for r/r CD19+ B-ALL (NCT05639179) | 920th Hospital of Joint Logistics Support Force of People's Liberation Army of China | 2022-12-05 |
| Study Evaluating the Safety and the Efficacy of Combination of Atezolizumab, Tiragolumab and and Stereotactic Body Radiation Therapy in Patients With Oligometastatic Multiorgan (IMMUNOs-SBRT) (NCT05259319) | Centre Georges Francois Leclerc | 2022-12-05 |
| A Bioequivalence Study of Mirikizumab (LY3074828) Solution in Healthy Participants (NCT05644353) | Eli Lilly and Company | 2022-12-05 |
| Studying the Safety, Efficacy, and Pharmacokinetic Characteristics of BNCT in Patients With Recurrent High-grade Gliomas (NCT05737212) | Dawonmedax Co., Ltd. | 2022-12-05 |
| A Study to Evaluate the Safety of mRNA-0184 in Participants With Heart Failure (NCT05659264) | ModernaTX, Inc. | 2022-12-05 |
| A Study to Investigate the Safety, Tolerability, and Pharmacokinetics (PK) of Oral AZD6793 in Healthy and Chronic Obstructive Pulmonary Disease Participants, to Assess the Relative Oral Bioavailability Between Two Formulations, and the Food Effect on the PK of AZD6793 Compared to Fasting State. (NCT05662033) | AstraZeneca | 2022-12-05 |
| Low-dose Interleukin-2 and Rapamycin on sjögren's Syndrome (NCT05605665) | Peking University People's Hospital | 2022-12-05 |
| Cord Blood Cells in Patients With Acute SCI (NCT05693181) | Sklifosovsky Institute of Emergency Care | 2022-12-05 |
| Safety and Efficacy Study of Topical DLQ01 in the Treatment of Androgenetic Alopecia (AGA) in Men (NCT05636904) | Dermaliq Therapeutics, Inc. | 2022-12-05 |
| Thorough QT/QTc of Pritelivir in Healthy Subjects (NCT05671029) | AiCuris Anti-infective Cures AG | 2022-12-04 |
| Pharmacokinetics of Chiglitazar in Subjects With Hepatic Impairment and Normal Hepatic Function (NCT05515445) | Chipscreen Biosciences, Ltd. | 2022-12-03 |
| A Study to Investigate the Pharmacokinetics of RO7223280 in Critically Ill Participants With Bacterial Infections (NCT05614895) | Hoffmann-La Roche | 2022-12-03 |
| A Study to Investigate Safety, Tolerability, and Pharmacokinetics (PK) of VH4524184 and the Potential for Changes in Cytochrome P450 3A (CYP3A) Activity (NCT05631704) | ViiV Healthcare | 2022-12-02 |
| A Phase I Study to Investigate the Safety, Tolerability and PK of HLX60 (Anti-GARP Monoclonal Antibody) in Subjects With Solid Tumors or Lymphoma (NCT05606380) | Shanghai Henlius Biotech | 2022-12-02 |
| A Multiple Dose Trial of Emraclidine in Elderly Participants and in Participants With Dementia Due to Alzheimer's Disease (NCT05644977) | AbbVie | 2022-12-02 |
| Study of Elacestrant in Combination With Onapristone in Patients With Advanced or Metastatic Breast Cancer (NCT05618613) | Context Therapeutics Inc. | 2022-12-02 |
| A Phase 1 Study of MRTX0902 in Solid Tumors With Mutations in the KRAS MAPK Pathway (NCT05578092) | Mirati Therapeutics Inc. | 2022-12-02 |
| Effects of Triiodothyronine (T3) in Ischemic Heart Failure (NCT05384847) | Emory University | 2022-12-02 |
| Phase 1 Study of PK and Safety of HM15912 (Sonefpeglutide) in Subjects With Normal and Severe Kidney Function (NCT05711381) | Hanmi Pharmaceutical Company Limited | 2022-12-02 |
| Phase One Clinical Trial to Assess the Safety, Tolerability and Pharmacokinetics of MSP008-22 in Healthy Adult Volunteers (NCT05532293) | Godavari Biorefineries Limited | 2022-12-02 |
| Pharmacokinetics and Safety Study of Siremadlin (HDM201) in Participants With Mild, Moderate and Severe Hepatic Impairment (NCT05599932) | Novartis Pharmaceuticals | 2022-12-02 |
| Deferoxamine in Aneurysmal Subarachnoid Hemorrhage Trial (NCT02875262) | Radboud University Medical Center | 2022-12-02 |
| A Phase 1a Trial to Evaluate the Safety and Immunogenicity of a SARS-CoV-2 mRNA Chimera Vaccine Against COVID-19 (NCT05394012) | Walvax Biotechnology Co., Ltd. | 2022-12-01 |
| CAR-NK Targeted CD19 for r/r B-cell Malignancies (NCT05645601) | Affiliated Hospital to Academy of Military Medical Sciences | 2022-12-01 |
| Camrelizumab Combined With Bevacizumab and HAIC in Patients With Metastatic Liver Cancer Who Failed Standard Therapy (NCT05643417) | Fudan University | 2022-12-01 |
| A Phase I Dose-finding Trial of Hyperthermic Intraperitoneal Paclitaxel Combined With Cisplatin (NCT05620654) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2022-12-01 |
| LITT Combined With Early Use of Temozolomide for Recurrent Glioblastomas (NCT05663125) | Beijing Tiantan Hospital | 2022-12-01 |
| Bioequivalence Study of Sulfadoxine/ Pyrimethamine Dispersible Tablets in Healthy Subjects Under Fasting Conditions (NCT05497063) | Emzor Pharmaceutical Industries Limited | 2022-12-01 |
| Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for OA (NCT05147675) | The Foundation for Orthopaedics and Regenerative Medicine | 2022-12-01 |
| Autologous Adoptive T Regulatory Cell Transfer in Autoimmune Diseases. (NCT05566977) | Ain Shams University | 2022-12-01 |
| Pembrolizumab and Trifluridine/Tipiracil With Previously Treated Advanced Gastric Cancer (NCT05508737) | Yonsei University | 2022-12-01 |
| A Trial of SHR-A1921 for Injection in Subjects With Advanced Solid Tumors (NCT05594875) | Atridia Pty Ltd. | 2022-12-01 |
| Randomized Trial Comparing Single vs. Maintenance Fecal Microbiota Transplant for Refractory Crohn's Disease in Children (NCT03747718) | Stanford University | 2022-12-01 |
| Chlorhexidine Mouthwash and Oral Nitrate in Adults With Pulmonary Hypertension (NCT03787082) | Gladwin, Mark, MD | 2022-12-01 |
| Study of LTC004 in Subjects With Advanced Malignant Tumors (NCT05666635) | Letolab | 2022-12-01 |
| Safety and Target Engagement of Centella Asiatica in Cognitive Impairment (NCT05591027) | Oregon Health and Science University | 2022-12-01 |
| Study to Assess an Anti-Trop2 Antibody Drug Conjugate in Relapsed or Refractory Solid Tumors (NCT05060276) | Sorrento Therapeutics, Inc. | 2022-12-01 |
| An Exploratory Safety and Efficacy Clinical Study of CARDIX-101 for the Treatment of Chronic Bradycardia (NCT05117346) | Cardix Therapeutics LLC | 2022-12-01 |
| A Phase 1 Study to Evaluate Safety and Tolerability of Single and Multiple Ascending Doses of XEN-101 (NCT05667129) | Xeno Biosciences | 2022-12-01 |
| FTIH of ECC5004 in Healthy and Diabetic Participants (NCT05654831) | Eccogene | 2022-12-01 |
| Dexamethasone in the Prevention of Post-spinal Paralytic Ileus After Cesarean Section (NCT05654649) | Assiut University | 2022-12-01 |
| A Study Evaluating SYHX2005 in the Treatment of Patients With Advanced Solid Tumors (NCT05609019) | CSPC Ouyi Pharmaceutical Co., Ltd. | 2022-12-01 |
| A Study of B1962, a PD-L1/VEGF Bispecific Antibody Fusion Protein, for Advanced Solid Tumors (NCT05650385) | Tasly Biopharmaceuticals Co., Ltd. | 2022-12-01 |
| Study of the ZN-d5 and ZN-c3 in Subjects With Acute Myeloid Leukemia (AML) (NCT05682170) | K-Group Alpha, Inc., a wholly owned subsidiary of Zentalis Pharmaceuticals, Inc. | 2022-12-01 |
| Pembrolizumab, Belantamab and Dexamethasone in Refractory Multiple Myeloma. (NCT05493618) | Hackensack Meridian Health | 2022-12-01 |
| Synapse 3D With Intravascular Indocyanine Green (NCT03953144) | St. Joseph's Healthcare Hamilton | 2022-12-01 |
| CD19 CAR-T Expressing IL-7 and CCL19 Combined With Anti-PD1 in RR-DLBCL (NCT05659628) | Ningbo No. 1 Hospital | 2022-12-01 |
| ThisCART19A Bridging to alloHSCT for R/R B-ALL (NCT05679687) | The First Affiliated Hospital of Soochow University | 2022-12-01 |
| KYSA-3: A Study of Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis (NCT06342960) | Kyverna Therapeutics | 2022-12-01 |