| A Phase 1 Study to Investigate Safety, Tolerability, and Pharmacokinetics of CK-0045 in Healthy Participants and Otherwise Healthy Participants With Obesity (NCT05712876) | Cytoki Pharma | 2022-12-26 |
| Natural Killer (NK) Cell Therapy Targeting CD33 in Acute Myeloid Leukemia (NCT05665075) | Zhejiang University | 2022-12-24 |
| Natural Killer(NK) Cell Therapy in r/r AML (NCT05665114) | Zhejiang University | 2022-12-24 |
| PM534 Administered Intravenously to Patients With Advanced Solid Tumors (NCT05835609) | PharmaMar | 2022-12-23 |
| The Effect of Platelet Rich Plasma (PRP) Application on Rotator Cuff Tear. (NCT07456215) | Aristotle University Of Thessaloniki | 2022-12-23 |
| ALG.APV-527 First-in-human Study (NCT05934539) | Aptevo Therapeutics | 2022-12-23 |
| Study to Evaluate the Pharmacokinetics and Safety of Oral Decitabine and Cedazuridine in Cancer Patients With Hepatic Impairment (NCT04953910) | Taiho Oncology, Inc. | 2022-12-23 |
| The Effect of Biktarvy (B/F/TAF) on Whole-body Insulin Sensitivity, Lipid and Endocrine Profile in Healthy Volunteers (NCT04950530) | Chelsea and Westminster NHS Foundation Trust | 2022-12-22 |
| Safety and Pharmacokinetics of GH002 in Healthy Volunteers (NCT05753956) | GH Research Ireland Limited | 2022-12-22 |
| A Study Evaluating Safety, Tolerability, and Pharmacokinetics of QRL-101 in Healthy Participants (NCT05667779) | QurAlis Corporation | 2022-12-22 |
| A GBT021601 ADME Microtracer Study in Healthy Volunteers (NCT05718687) | Pfizer | 2022-12-22 |
| Chidamide Prevents Recurrence of High-risk AML After Allo-HSCT (NCT05682755) | Sichuan University | 2022-12-22 |
| Efficacy of a Single Image Guided Injection of CTM for Glenohumeral Arthritis (NCT06171542) | Indiana Hand to Shoulder Center | 2022-12-22 |
| Safety and Tolerability of ²¹²Pb-DOTAM-GRPR1 in Adult Subjects With Recurrent or Metastatic GRPR-expressing Tumors (NCT05283330) | Orano Med Theranostics, SAS | 2022-12-22 |
| Mosunetuzumab Consolidation Therapy After autoSCT in r/r Aggressive B Cell Lymphoma (NCT05412290) | Washington University School of Medicine | 2022-12-22 |
| Delayed Immunological Tolerance in Patients With Well-functioning Pre-existing HLA-matched Kidney Transplants (NCT05525507) | University of California, Los Angeles | 2022-12-21 |
| A Study to Understand How the Study Medicine (PF-07081532) is Processed and Eliminated in Healthy Men (NCT05652647) | Pfizer | 2022-12-21 |
| A Study of MK-6598 as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Advanced Solid Tumors (MK-6598-001) (NCT05594043) | Merck Sharp & Dohme LLC | 2022-12-21 |
| A Phase 1/2, Open-label, Multicenter, Dose Escalation and Expansion Study of SLC-3010 Monotherapy and in Combination (NCT05525247) | Selecxine | 2022-12-21 |
| Dual BET and CBP/p300 Inhibitor in Patients With Targeted Advanced Solid Tumors and Hematological Malignancies (NCT05488548) | Epigenetix, Inc. | 2022-12-21 |
| Periocular Rejuvenation by Topical Hyaluronic Acid Nano Particles (NCT05742399) | Alexandria University | 2022-12-21 |
| First in Human Study of AZD9592 in Solid Tumors (NCT05647122) | AstraZeneca | 2022-12-21 |
| Investigation of Profile-related Evidence Determining Individualized Cancer Therapy for Patients With Aggressive Malignancies and Poor Prognoses (NCT05674825) | Medical College of Wisconsin | 2022-12-21 |
| Clinical And Radiographic Evaluation Of Nano-Propolis, Nano-Curcumin and MTA as Direct Pulp Capping Agents in Young Permanant Teeth (NCT06029023) | Al-Azhar University | 2022-12-20 |
| Effects of CSL324 in the Lung After Segmental Challenge (NCT05653713) | CSL Behring | 2022-12-20 |
| A Clinical Trial of PR001 (LY3884961) in Patients With Peripheral Manifestations of Gaucher Disease (PROCEED) (NCT05487599) | Prevail Therapeutics | 2022-12-20 |
| Study to Determine the Safety and Pharmacokinetics of DO-2 in Patients With Advanced or Refractory Solid Tumours (NCT05752552) | DeuterOncology | 2022-12-20 |
| A Study to Assess Safety, Tolerability, and Pharmacokinetics of AZD0186 (NCT05694741) | AstraZeneca | 2022-12-20 |
| Pamiparib (BGB-290) Was Used in EGFR-TkIs Resistant Non-small Cell Lung Cancer (NCT05573373) | Affiliated Hospital of Jiangnan University | 2022-12-20 |
| IFN-γ Combined With T Cells in the Treatment of Refractory Malignant Pleural Effusion and Ascites (NCT05268172) | Affiliated Hospital of Jiangnan University | 2022-12-20 |
| A Phase I Study to Assess PSMA+ and PSMA- Tumour Lesions (NCT05836623) | Crescendo Biologics Ltd. | 2022-12-20 |
| Dose-finding and Dose Expansion Study of OSE-279 in Subjects With Advanced Solid Tumors or Lymphomas (NCT05751798) | OSE Immunotherapeutics | 2022-12-20 |
| To Evaluate the Safety, Tolerability, and Pharmacokinetics After Subcutaneous Administration of C1K in Healthy Subjects (NCT05980065) | Seoul National University Hospital | 2022-12-20 |
| A Study of YL202 in Patients With Locally Advanced or Metastatic Non-small Cell Lung Cancer and Breast Cancer (NCT05653752) | MediLink Therapeutics (Suzhou) Co., Ltd. | 2022-12-20 |
| A Clinical Trial to Compare and Evaluate the Safety and Pharmacokinetics of CKD-391 (NCT05634447) | Chong Kun Dang Pharmaceutical | 2022-12-20 |
| JAB-2485 Activity in Adult Patients With Advanced Solid Tumors (NCT05490472) | Jacobio Pharmaceuticals Co., Ltd. | 2022-12-20 |
| A Trial of Lu AG13909 in Participants With Congenital Adrenal Hyperplasia (NCT05669950) | H. Lundbeck A/S | 2022-12-19 |
| Study of ExoFlo for the Treatment of Medically Refractory Ulcerative Colitis (NCT05176366) | Direct Biologics, LLC | 2022-12-19 |
| A Study to Evaluate the Safety, Tolerability, and Pharmacodynamics of SEL-302 in Pediatric Subjects With MMA (NCT05778877) | Selecta Biosciences, Inc. | 2022-12-19 |
| A Study of the Interaction of Tunodafil Hydrochloride Tablets and Alcohol (NCT05976503) | Yangtze River Pharmaceutical Group Co., Ltd. | 2022-12-19 |
| A JZP341 Study in Adult Participants With Advanced or Metastatic Solid Tumors (NCT05631327) | Jazz Pharmaceuticals | 2022-12-19 |
| A Study to Investigate LYL845 in Adults With Solid Tumors (NCT05573035) | Lyell Immunopharma, Inc. | 2022-12-19 |
| CC-486 and Venetoclax for Acute Myeloid Leukemia (NCT05287568) | University of Colorado, Denver | 2022-12-19 |
| A Gene Transfer Single Dose Study to Evaluate the Safety, Tolerability and Efficacy of SRP-9003 in Non-Ambulatory and Ambulatory Participants With Limb Girdle Muscular Dystrophy, Type 2E/R4 (Beta-Sarcoglycan [β-SG] Deficiency) (NCT05876780) | Sarepta Therapeutics, Inc. | 2022-12-19 |
| Evaluation of Safety and Pharmacokinetics of Oral Controlled-ileal-release Nicotinic Acid (CIR-NA) Compared to Immediate-release Nicotinic Acid and Placebo in Healthy Subjects and Subjects With Prediabetes (NCT06378125) | University Hospital Schleswig-Holstein | 2022-12-19 |
| Study to Evaluate Safety, Tolerability and Pharmacokinetics of CS0159 in Chinese Healthy Subjects (NCT05624294) | Cascade Pharmaceuticals, Inc | 2022-12-19 |
| Study of SHR6390 in Renal Insufficiency and Healthy Subjects (NCT05515289) | Jiangsu HengRui Medicine Co., Ltd. | 2022-12-18 |
| A Clinical Study of GZR33 and GZR101 in Healthy Subjects (NCT06556641) | Gan and Lee Pharmaceuticals, USA | 2022-12-17 |
| A Dose Calibration Study Comparing IkT-001Pro to Imatinib Mesylate 400mg (NCT05623774) | Inhibikase Therapeutics | 2022-12-16 |
| Beta-blocker Administration for Cardiomyocyte Division (NCT04713657) | Weill Medical College of Cornell University | 2022-12-16 |
| A First-in-human Study of YN001 in Healthy Volunteers (NCT05635084) | Beijing Inno Medicine Co., Ltd. | 2022-12-16 |
| Study of [4-14C] AEF0117 Following a Single Oral Dose in Healthy Male Subjects (NCT05554926) | Aelis Farma | 2022-12-16 |
| A Study of ANV419 Alone or in Combination With Approved Treatment in Patients With Cutaneous Melanoma (OMNIA-1). (NCT05578872) | Anaveon AG | 2022-12-16 |
| Kisspeptin Administration Subcutaneously to Patients With Reproductive Disorders (NCT05633966) | Stephanie B. Seminara, MD | 2022-12-16 |
| A Study to Investigate the PK, Safety, and Tolerability Between AVT05, US and EU Simponi® in Healthy Adult Participants (NCT05632211) | Alvotech Swiss AG | 2022-12-16 |
| A Study Evaluating the Safety and Tolerability of QRL-201 in ALS (NCT05633459) | QurAlis Corporation | 2022-12-16 |
| The Application of Ursodeoxycholic Acid for the Prevention of SARS-CoV-2 Infection (COVID-19) (NCT05659654) | Institute of Hematology & Blood Diseases Hospital, China | 2022-12-16 |
| Evaluation of the Effects of Omeprazole and Rifampin on the Pharmacokinetics of VX-548 in Healthy Participants (NCT05635110) | Vertex Pharmaceuticals Incorporated | 2022-12-15 |
| Study of CHS-114 in Participants With Advanced Solid Tumors (NCT05635643) | Coherus Oncology, Inc. | 2022-12-15 |
| Contrast-Enhanced Ultrasound and Shear Wave Elastography for the Treatment of Lymphedema (NCT05613946) | Mayo Clinic | 2022-12-15 |
| Phase 1/2 Trial of AEF0217 in Participants With Down Syndrome (NCT05748405) | Aelis Farma | 2022-12-15 |
| Clinical Study of Cord Blood-derived CAR NK Cells Targeting CD19/CD70 in Refractory/Relapsed B-cell Non-Hodgkin Lymphoma (NCT05667155) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2022-12-15 |
| NP-101 (TQ Formula) With Nivolumab and Ipilimumab in Advanced or Metastatic Extra-pulmonary Neuroendocrine Carcinomas (NCT05262556) | Amr Mohamed MD | 2022-12-15 |
| Neoantigen Vaccines in Pancreatic Cancer in the Window Prior to Surgery (NCT05111353) | Washington University School of Medicine | 2022-12-15 |
| Multiple-dose Trial to Determine the Clinical Bioequivalence Between Tavapadon Tablets in Participants With Parkinson's Disease (NCT05610189) | Cerevel Therapeutics, LLC | 2022-12-15 |
| Ori-C101Chimeric Antigen Receptor (CAR) Modified T Cells for the Treatment of HCC (NCT05652920) | OriCell Therapeutics Co., Ltd. | 2022-12-15 |
| Study of AK119 Combined With AK104 in Patients With Advanced Solid Tumors (NCT05559541) | Akeso | 2022-12-15 |
| Aom0319 SAD Study in Healthy Subjects (NCT05555758) | Amckaus PTY LTD. | 2022-12-15 |
| A Maintenance Therapy Study of Odetiglucan With CDX-1140 in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (NCT05484011) | HiberCell, Inc. | 2022-12-15 |
| A Clinical Study to Evaluate Safety, Tolerance, Pharmacokinetics and Efficacy of Sc610 Injection for Treating Advanced Urinary System Tumors (NCT05633589) | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | 2022-12-15 |
| Evaluation of the Safety and Efficacy of Esperanza Extract (PA001) (NCT05587088) | Hospital Universitario San Ignacio | 2022-12-15 |
| TT-4 As a Single Agent in Subjects with Advanced Selected Solid Tumors (NCT04976660) | Tarus Therapeutics, Inc. | 2022-12-15 |
| Phase I/IIa Study of H002 in NSCLC With Active EGFR Mutation (NCT05519293) | RedCloud Bio | 2022-12-15 |
| First in Human Safety Study of FX-345 in Adults With Sensorineural Hearing Loss (NCT05664100) | Frequency Therapeutics | 2022-12-15 |
| Colchicine in Patients With Heart Failure and Preserved Left Ventricular Ejection Fraction (NCT05637398) | I.M. Sechenov First Moscow State Medical University | 2022-12-15 |
| Effect of Mesenchymal Stem Cells on Healing of Foot Ulcers in Diabetes Patients. (NCT05595681) | Cell to Cure ApS | 2022-12-15 |
| Hyperpolarized 13C MRI as a Biomarker in Advanced Solid Tumors (NCT05599048) | Robert Bok, MD, PhD | 2022-12-15 |
| Safety and Immune Responses After Vaccination With an Investigational RNA-based Vaccine Against Malaria (NCT05581641) | BioNTech SE | 2022-12-15 |
| Pharmacokinetics and Safety of GST-HG171 Tablets in Subjects With Impaired and Normal Liver Function (NCT06106113) | Fujian Akeylink Biotechnology Co., Ltd. | 2022-12-15 |
| A Phase 1 Dose Escalation Study of VX-993 in Healthy Participants (NCT05653323) | Vertex Pharmaceuticals Incorporated | 2022-12-14 |
| A Clinical Trial of Four Medicines (Elranatamab Plus Carfilzomib and Dexamethasone or Maplirpacept) in People With Relapsed Refractory Multiple Myeloma (NCT05675449) | Pfizer | 2022-12-14 |
| Combined Evaluation of Epigenetic and Sensitising Therapy in AML and MDS (NCT05636514) | Clinical Hub for Interventional Research (CHOIR) | 2022-12-14 |
| Phase I Study of ZN-c3 and Bevacizumab ± Pembrolizumab in Metastatic CCNE1 Amplified and TP53 Mutant Solid Tumors (NCT05431582) | M.D. Anderson Cancer Center | 2022-12-14 |
| Phase 1, First-in-human, Dose-finding and Expansion Study to Evaluate XmAb®808 in Combination With Pembrolizumab in Advanced Solid Tumors (NCT05585034) | Xencor, Inc. | 2022-12-14 |
| A Phase I of SS109 in Hemophilia A or and B With Inhibitors (NCT05651061) | Hangzhou Gensciences Biopharmaceutical Co., Ltd. | 2022-12-14 |
| A Study to Investigate the Safety, Tolerability and Efficacy of HLX60 Combination With HLX10 in Subjects With Advanced or Metastatic Solid Tumors (NCT05483530) | Shanghai Henlius Biotech | 2022-12-14 |
| ADME Study of [14^C]-Ibrexafungerp in Healthy Male Subjects (NCT05668429) | Scynexis, Inc. | 2022-12-14 |
| Safety, Tolerability, PK, PD of ADX-324 in Healthy Volunteers and Hereditary Angioedema Patients (NCT05691361) | ADARx Pharmaceuticals, Inc. | 2022-12-14 |
| Evaluation of the Safety and the Tolerability of a Combination of Two HIV Inducers in Patients With Undetectable Viral Load (NCT05230368) | ANRS, Emerging Infectious Diseases | 2022-12-14 |
| Safety and Immunogenicity of ChulaCov19 BNA159 mRNA Vaccine (NCT05231369) | Chulalongkorn University | 2022-12-14 |
| Open-label Extension (OLE) Study of WVE-004 in Patients With C9orf72-associated Amyotrophic Lateral Sclerosis (ALS) and/or Frontotemporal Dementia (FTD) (NCT05683860) | Wave Life Sciences USA, Inc. | 2022-12-14 |
| BAL0891 in Patients With Advanced Solid Tumors or Relapsed or Refractory Acute Myeloid Leukemia (NCT05768932) | SillaJen, Inc. | 2022-12-14 |
| A Study of Amivantamab and Capmatinib Combination Therapy in Unresectable Metastatic Non-small Cell Lung Cancer (NCT05488314) | Janssen Research & Development, LLC | 2022-12-13 |
| SPL026 With or Without SSRIs in Participants With MDD (NCT05553691) | Small Pharma Ltd | 2022-12-13 |
| A Phase 1/2 Study to Investigate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, and Efficacy of HMB-001 in Glanzmann Thrombasthenia (NCT06211634) | Hemab ApS | 2022-12-13 |
| A Study to Compare the Pharmacokinetics (PK) of Depemokimab When Delivered With a Safety Syringe Device (SSD) or an Autoinjector in Healthy Adult Participants (NCT05602025) | GlaxoSmithKline | 2022-12-13 |
| Long Acting Neuraxial Peri-prostatic Block in Cancer (NCT06703437) | Icahn School of Medicine at Mount Sinai | 2022-12-13 |
| Safety and Immunogenicity of Quadrivalent Influenza mRNA Vaccine MRT5413 in Adult Participants18 Years of Age and Older (NCT05650554) | Sanofi Pasteur, a Sanofi Company | 2022-12-12 |
| Multiple Dose Study of Safety and Pharmacokinetics of MEDI0618 in Healthy Volunteers (NCT05714254) | AstraZeneca | 2022-12-12 |
| A Phase 1 Study With LYT-200 in Patients With Relapsed/Refractory Acute Myeloid Leukemia (AML), or With Relapsed/Refractory, High-risk Myelodysplastic Syndrome (MDS) (NCT05829226) | PureTech | 2022-12-12 |