| Early Bactericidal Activity, Safety & Tolerability of Oral GSK3036656 in a Dual Combination With Novel and Established Antitubercular Agents, or Standard of Care in Adults With Rifampicin Susceptible Pulmonary Tuberculosis (NCT05382312) | GlaxoSmithKline | 2022-07-26 |
| A Systemic Screening for TB Disease in High-risk Groups in Barcelona (NCT06706596) | Fundació Institut Germans Trias i Pujol | 2022-07-22 |
| Effect of Integrating Traditional Tuberculosis Care With Modern Health Care on Case Detection (NCT05236452) | Bahir Dar University | 2022-07-01 |
| Oral Vitamin D and Toll Like Receptor in Spondylitis Tuberculosis (NCT05376189) | Hasanuddin University | 2022-07-01 |
| A Phase 1, Drug-Drug Interaction Study of TBAJ-876 in Healthy Adults (NCT05526911) | Global Alliance for TB Drug Development | 2022-06-30 |
| Host Blood RNA Signatures for Diagnosis of TB (NCT05542511) | University of Stellenbosch | 2022-06-23 |
| Preventive Treatment Of Latent Tuberculosis Infection In People With Diabetes Mellitus (NCT04600167) | Dr. Nyanda Elias Ntinginya | 2022-06-17 |
| Community Health Worker Training to Reduce Depression and Substance Use Stigma in TB/HIV Care in South Africa (NCT05282173) | University of Maryland, College Park | 2022-06-08 |
| Endobronchial Ultrasound Needle Aspiration With and Without Suction (NCT05110950) | Università Politecnica delle Marche | 2022-06-01 |
| Effectiveness Of Mobile Application To Improve Adherence To Tuberculosis Treatment (NCT05259254) | Mohd Fazeli bin Sazali | 2022-06-01 |
| Triage Test for All Oral DR-TB Regimen (TRiAD Study) (NCT05175794) | Centre for the AIDS Programme of Research in South Africa | 2022-05-26 |
| Aerosol BCG Challenge Study in Historically BCG-vaccinated Volunteers (NCT04777721) | University of Oxford | 2022-05-17 |
| Whole Genome Sequencing of Tuberculosis for Disease Control in Madagascar (NCT05406453) | Institut Pasteur de Madagascar | 2022-05-16 |
| Determination of Adequate Tuberculosis Regimen in Patients Hospitalized With HIV-associated Severe Immune Suppression (NCT04738812) | ANRS, Emerging Infectious Diseases | 2022-04-21 |
| Cough Audio Classification as a TB Triage Test (NCT05317247) | University of Stellenbosch | 2022-04-19 |
| My Mobile Wallet: An Intervention for Tuberculosis Medication Adherence in Rural Uganda (NCT05656287) | Mbarara University of Science and Technology | 2022-04-14 |
| The Prophylaxis of Tuberculosis According to TSPOT Results After Kidney Transplantation (NCT05249699) | West China Hospital | 2022-04-01 |
| Ultra Curto (Ultra Short) TB Prevention Therapy (NCT04703075) | Johns Hopkins University | 2022-03-24 |
| Human-centered Design and Communities of Practice to Improve Home-based Tuberculosis Contact Investigation in Uganda (NCT05640648) | Yale University | 2022-03-07 |
| Safety and Tolerability of Metformin in People With Tuberculosis (TB) and Human Immunodeficiency Virus (HIV) (NCT04930744) | University of Massachusetts, Worcester | 2022-03-04 |
| Health and Migration Trajectories of Housekeepers in Bamako (NCT05472051) | ANRS, Emerging Infectious Diseases | 2022-02-28 |
| A Multicenter Clinical Trial of Sputum DNA Testing for Lung Cancer in China (NCT05337163) | Creative Biosciences (Guangzhou) Co., Ltd. | 2022-02-25 |
| Evaluating the Impact of Computer-assisted X-ray Diagnosis and Other Triage Tools to Optimise Xpert Orientated Community-based Active Case Finding for TB and COVID-19 (NCT05220163) | University of Cape Town | 2022-02-23 |
| A Phase Ⅱ Clinical Trial of the Recombinant Mycobacterium Tuberculosis Vaccine Freeze-dried (AEC/BC02) (NCT05284812) | Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd. | 2022-02-10 |
| A Trial of Radial EBUS Versus VBN for the Peripheral Pulmonary Lesions (NCT05739695) | Ilya Sivokozov | 2022-02-01 |
| Tuberculosis Drug Levels and Continuous Glucose Monitoring in Diabetic Patients (NCT05329415) | London North West Healthcare NHS Trust | 2022-02-01 |
| Pharmacokinetics of Drugs Used to Treat Drug Sensitive Tuberculosis in Breastfeeding Mother-infant Pairs (NCT05840809) | University of Liverpool | 2022-01-20 |
| Study of the Safety and Efficacy of the Subunit Recombinant Tuberculosis Vaccine GamTBvac (NCT04975737) | Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation | 2022-01-20 |
| Early Empiric Anti-Mycobacterium Tuberculosis Therapy for Sepsis in Sub-Saharan Africa (NCT04618198) | University of Virginia | 2021-12-10 |
| Pharmacogenetics-guided Isoniazid Dosing in TB-HIV (NCT05124678) | Makerere University | 2021-12-07 |
| eNose-TB: Electronic Nose for Tuberculosis Screening (NCT04567498) | Gadjah Mada University | 2021-12-02 |
| Evaluation of Efficacy and Safety of the Concomitant of RUTI® Immunotherapy With the Standard Treatment in TB Patients (NCT05136833) | Archivel Farma S.L. | 2021-12-01 |
| Evaluating a New Stool Based qPCR for Diagnosis of Tuberculosis in Children and People Living With HIV (NCT05047315) | Barcelona Institute for Global Health | 2021-12-01 |
| Utilizing the Crosstalk Among Chicoric Acid, 13-Cis Retinoic Acid(Aerosolized), Minocycline and Vitamin D as a Potent Quadrate Therapy for Treating Patients With Multidrug-resistant TB and Patient With Both Multidrug-resistant TB and COVID-19 (NCT05077813) | Kafrelsheikh University | 2021-12-01 |
| Randomized Clinical Trial: IS Zinc and Zinc Ionophere EGCG as Supplement Improve Outcome of Active Pulmonary Tuberculosis (NCT05116098) | Ministry of Health, Saudi Arabia | 2021-11-30 |
| Specificity Trial of the Recombinant Tuberculosis Allergen in BCG Vaccinated Healthy Volunteers (NCT05203068) | National Medical Research Center of Phthisiopulmonology and Infectious Diseases | 2021-11-24 |
| Validation of Artificial Intelligence Enabled TB Screening and Diagnosis in Zambia (NCT05139940) | Centre for Infectious Disease Research in Zambia | 2021-11-22 |
| Drug Interactions Between Dolutegravir and Escalating Doses of Rifampicin (NCT04166474) | Helen Reynolds | 2021-11-18 |
| Impact of Malnutrition on Pharmacokinetic of Rifampicin, Isoniazid, Pyrazinamide and Ethambutol in TB-HIV Co-infected Children (TB-Speed TB-PK) (NCT04972903) | Institut National de la Santé Et de la Recherche Médicale, France | 2021-11-08 |
| Dried Blood Spot Test to Assess TB in Pregnancy (NCT04871230) | Institut Pasteur de Madagascar | 2021-10-27 |
| Interrupting HIV and TB Stigma in the Household in Uganda (NCT05124665) | Yale University | 2021-10-25 |
| Triage UltraSound in Tb Endemic Regions (NCT05423847) | Centre Hospitalier Universitaire Vaudois | 2021-10-14 |
| Absorption, Elimination and Safety of 14C-labeled Radioactive BTZ-043, a New Compound in TB Treatment (NCT04874948) | Michael Hoelscher | 2021-10-08 |
| Airborne Preventive Measures to Reduce New TB Infections in Household Contacts (NCT04938596) | Pontificia Universidad Catolica de Chile | 2021-10-04 |
| Improved Diagnostics for Paediatric Tuberculosis (NCT06944561) | St George's, University of London | 2021-10-04 |
| Inpatient Package to Reduce HIV and AIDS-related Death in Zambia (NCT04033718) | University of Alabama at Birmingham | 2021-10-01 |
| A Trial to Evaluate the Male Reproductive Safety of Pretomanid in Adult Male Participants With Drug Resistant Pulmonary Tuberculosis (NCT04179500) | Global Alliance for TB Drug Development | 2021-09-16 |
| Acoustic Cough Monitoring for the Management of Patients With Known Respiratory Disease (NCT05042063) | Clinica Universidad de Navarra, Universidad de Navarra | 2021-09-15 |
| Prevent TB: Choice Architecture for TPT Delivery (NCT04466488) | Johns Hopkins University | 2021-09-15 |
| Community Initiated Preventive Therapy for TB (NCT04369326) | Johns Hopkins University | 2021-09-07 |
| TB and Sarcoidosis Granuloma (NCT06396910) | Karolinska Institutet | 2021-09-01 |
| Pharmacokinetic Properties of Antiretroviral and Anti-Tuberculosis Drugs During Pregnancy and Postpartum (NCT04518228) | National Institute of Allergy and Infectious Diseases (NIAID) | 2021-09-01 |
| Potential Role of Microbiome in Tuberculosis (NCT04985994) | Khyber Medical University Peshawar | 2021-08-22 |
| Pharmacokinetics of Twice or Once Daily DTG (50mg) in Children With HIV and TB (NCT04746547) | University of KwaZulu | 2021-08-19 |
| PREVAIL VIIIa: Evaluation of Latent Tuberculosis Infection Screening Methods in People Living With Retroviral Infection in Liberia (NCT04926922) | National Institute of Allergy and Infectious Diseases (NIAID) | 2021-07-27 |
| A Real-world Study of Tuberculosis Incidence in AS, PsA, or PsO Patients Treated With Secukinumab in Brazil (NCT06715254) | Novartis Pharmaceuticals | 2021-07-23 |
| Phase I Clinical Protocol for Pre-evaluation of the Safety of BCG-PPD in Tuberculosis Patients (NCT04538911) | Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd. | 2021-07-02 |
| Vitamin D Supplementation and TB (NCT01992263) | Cornell University | 2021-06-01 |
| TB-CAPT MTB/XDR Study (NCT04567368) | Foundation for Innovative New Diagnostics, Switzerland | 2021-05-14 |
| A Study of the Pharmacokinetic and Pharmacodynamic Interactions Between Bictegravir, Tenofovir Alafenamide and Rifapentine in Healthy Adult Subjects (NCT04551573) | Yale University | 2021-05-01 |
| Transmission of Tuberculosis Among Illicit Drug Use Linkages (NCT04151602) | Boston Medical Center | 2021-04-22 |
| Predicting the Future: Incipient Tuberculosis (NCT04825327) | Amsterdam Institute for Global Health and Development | 2021-04-21 |
| Rapid Research in Diagnostics Development for TB Network (NCT04923958) | University of California, San Francisco | 2021-04-14 |
| New Reusable Mask Design With Superior Filtration and Fit (NCT04826809) | Mayo Clinic | 2021-04-09 |
| Rifampicin at High Dose for Difficult-to-Treat Tuberculosis (NCT04768231) | Hospital Universitari Vall d'Hebron Research Institute | 2021-04-01 |
| Choice Architecture Based TB Preventive Therapy Prescribing (NCT04466293) | Johns Hopkins University | 2021-03-29 |
| Xpert Active Case-finding Trial 3 (XACT-3) (NCT04303104) | University of Cape Town | 2021-03-26 |
| Tuberculosis as a Risk Factor for a Worse Outcome Post-Sars-CoV-2 Infection (NCT05643781) | The Aurum Institute NPC | 2021-03-23 |
| Prevalence and Malignant Involvement of Calcified Intrathoracic Lymph Nodes in Patients Undergoing Endosonography (NCT04743583) | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 2021-03-20 |
| Novel Triple-dose Tuberculosis Retreatment Regimen (NCT04260477) | Institute of Tropical Medicine, Belgium | 2021-03-01 |
| Accessibility of the World Health Organization's eTB Catalogue of Recommendations (NCT04745897) | McMaster University | 2021-02-26 |
| Study to Evaluate Safety, Tolerability, and the PK Profile of TBI-223 in Healthy Subjects (NCT04865536) | Global Alliance for TB Drug Development | 2021-02-03 |
| Development of Molecular Diagnostic Platform for Tuberculosis (NCT04734236) | Asan Medical Center | 2021-01-28 |
| Treating Tuberculosis With the Lipid Lowering Drug Atorvastatin in Nigeria(ATORvastatin in Pulmonary TUBerculosis) (NCT04721795) | Obafemi Awolowo University Teaching Hospital | 2021-01-19 |
| TB PCR in BAL and EBUS-TBNA (NCT04909385) | Imperial College Healthcare NHS Trust | 2021-01-15 |
| Phenotyping of High Dose Rifampicin (NCT04525235) | Radboud University Medical Center | 2021-01-07 |
| Cyclophosphamide in the Treatment of Refractory Proliferative Arachnoiditis in CNS Tuberculosis (NCT04620772) | All India Institute of Medical Sciences | 2021-01-01 |
| Collect Data From Patients Receiving Standardized Anti-tuberculosis Therapy, Collect Monitoring Data, and Evaluate Treatment Efficacy and Potential Adverse Reactions. (NCT07607288) | Beijing Chest Hospital | 2021-01-01 |
| Impact of the Respiratory Isolation on the Quality of Life in Patients Hospitalized for Tuberculosis or COVID-19 (NCT04677478) | Assistance Publique - Hôpitaux de Paris | 2020-12-01 |
| Evaluation of the Safety, Tolerability, PK of TBAJ-587 in Healthy Adults (NCT04890535) | Global Alliance for TB Drug Development | 2020-12-01 |
| Influence of Filarial Infections on Tuberculosis Disease and Tuberculosis Vaccination in Cameroon (NCT04547738) | University Hospital, Bonn | 2020-12-01 |
| TB Treatment Support Tool Interactive Mobile App and Direct Adherence Monitoring on TB Treatment Outcomes (NCT04221789) | Institute for Clinical Effectiveness and Health Policy | 2020-11-17 |
| TB Screening Improves Preventive Therapy Uptake (NCT04557176) | University of California, San Francisco | 2020-11-16 |
| Point-of-care Triage Test for Active Tuberculosis (NCT04232618) | University of Stellenbosch | 2020-11-05 |
| Efficacy of 400 mg Efavirenz Versus Standard 600 mg Dose in HIV/TB Co-infected Patients (NCT04513379) | Shanghai Public Health Clinical Center | 2020-11-01 |
| Dose Escalation Study to Determine the Pharmacokinetics of Atazanavir Administered With RIfampicin to HIV Positive Adults on sEcond-line ART Regimen With Suppressed HIV-1 Viral Load (NCT04121195) | University of Liverpool | 2020-10-30 |
| A Study to Evaluate Safety, Tolerability and Pharmacokinetics of GSK2556286 in Healthy Adult Participants (NCT04472897) | GlaxoSmithKline | 2020-10-30 |
| A Clinical Trial of the Safety, Pharmacokinetics and Hematologic Effects of Imatinib on Myelopoiesis in Adults When Given With and Without Isoniazid and Rifabutin (NCT03891901) | National Institute of Allergy and Infectious Diseases (NIAID) | 2020-10-27 |
| Clinical Study of BCG Vaccine for Intradermal Injection (NCT04563273) | Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd. | 2020-10-21 |
| Phase I Clinical Protocol of BCG-PPD in Healthy People (NCT04593771) | Anhui Zhifei Longcom Biologic Pharmacy Co., Ltd. | 2020-10-21 |
| Impact of Mobile Health Interactive Software on Tuberculosis Outcomes; The Call for Life (CFLU-TB) Project (NCT04709159) | Makerere University | 2020-10-19 |
| Identifcation of Biomarkers for Active Pulmonary Tuberculosis (NCT04490746) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2020-10-01 |
| TB-LAM in the Diagnosis of TB (NCT04600232) | Shanghai Public Health Clinical Center | 2020-10-01 |
| Rifampin and the Contraceptive Implant (NCT04463680) | University of Colorado, Denver | 2020-09-23 |
| Kharituwe TB Contact Tracing Study (NCT04520113) | Johns Hopkins Bloomberg School of Public Health | 2020-09-01 |
| Evaluating the EBA of Meropenem With Amoxicillin/Clavulanate and Pyrazinamide or Bedaquiline in Adults With PTB (NCT04629378) | TASK Applied Science | 2020-08-17 |
| Randomized Controlled Multi-center Short Course Treatment for Rifampicin Resistant Tuberculosis (NCT04545788) | Beijing Chest Hospital | 2020-08-01 |
| The Role of a Mycobacterium Growth Inhibition Assay to Quantify Host Immune Control of M. Tuberculosis (NCT06580639) | Linkoeping University | 2020-08-01 |
| The Impact of Malnutrition on Immune Responses to Tuberculosis (NCT05044910) | Tuberculosis Research Centre, India | 2020-08-01 |
| Options for Delivering Isoniazid-Rifapentine (3HP) for TB Prevention (3HP Options Implementation Trial) (NCT03934931) | University of California, San Francisco | 2020-07-13 |