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Triple Negative Breast Neoplasms

62 clinical trials · Condition

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RecordFirmDate
Image-based AI Predictive Biomarkers for Precision Neoadjuvant Triple-negative Breast Cancer Treatment (NCT05435352)Ourotech, Inc.2022-06-06
NUV-868 as Monotherapy and in Combination With Olaparib or Enzalutamide in Adult Patients With Advanced Solid Tumors (NCT05252390)Nuvation Bio Inc.2022-03-29
A Study of Felmetatug Vedotin/SGN-B7H4V in Advanced Solid Tumors (NCT05194072)Seagen, a wholly owned subsidiary of Pfizer2022-01-12
Cyclin dEpendent Kinase in tRiple nEGatIVe brEast canceR - a "Window of Opportunity" Study (NCT05067530)Medical University of Gdansk2022-01-01
A Study of TAK-676 With Pembrolizumab After Radiation Therapy to Treat a Number of Cancers (NCT04879849)Takeda2021-09-09
A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors (NCT04895709)Bristol-Myers Squibb2021-05-27
Psychological Factors and Oncological Outcomes of Triple-negative Breast Cancer (NCT04669522)Pius-Hospital Oldenburg2020-12-01
Bintrafusp Alfa in High Mobility Group AT-Hook 2 (HMGA2) Expressing Triple Negative Breast Cancer (NCT04489940)EMD Serono Research & Development Institute, Inc.2020-10-12
First Time in Human Study of AZD8701 With or Without Durvalumab in Participants With Advanced Solid Tumours (NCT04504669)AstraZeneca2020-08-18
Study BT8009-100 in Subjects With Nectin-4 Expressing Advanced Malignancies (NCT04561362)BicycleTx Limited2020-07-17
Study Assessing the Efficacy and Safety of Alpelisib + Nab-paclitaxel in Subjects With Advanced TNBC Who Carry Either a PIK3CA Mutation or Have PTEN Loss (NCT04251533)Novartis Pharmaceuticals2020-06-08
NordicTrip, a Translational Study of Preoperative Chemotherapy in TNBC (NCT04335669)Lund University Hospital2019-12-20
Study of Olaparib Plus Pembrolizumab Versus Chemotherapy Plus Pembrolizumab After Induction With First-Line Chemotherapy Plus Pembrolizumab in Triple Negative Breast Cancer (TNBC) (MK-7339-009/KEYLYNK-009) (NCT04191135)Merck Sharp & Dohme LLC2019-12-19
Neoantigen DNA Vaccine Alone vs. Neoantigen DNA Vaccine Plus Durvalumab in Triple Negative Breast Cancer Patients Following Standard of Care Therapy (NCT03199040)Washington University School of Medicine2019-07-23
Evaluate the Clinical Benefit of a Post-operative Treatment Associating Radiotherapy + Nivolumab + Ipilimumab Versus Radiotherapy + Capecitabine for Triple Negative Breast Cancer Patients With Residual Disease (NCT03818685)Centre Leon Berard2019-07-02
Capivasertib+Paclitaxel as First Line Treatment for Patients With Locally Advanced or Metastatic TNBC (NCT03997123)AstraZeneca2019-06-25
Leronlimab (PRO 140) Combined With Carboplatin in Patients With Cytokine Chemokine Receptor 5 Positive (CCR5+) mTNBC (NCT03838367)CytoDyn, Inc.2019-04-22
A Study of Novel Anti-cancer Agents in Patients With Metastatic Triple Negative Breast Cancer (NCT03742102)AstraZeneca2018-12-21
Safety and Efficacy of SCT200 in Patients With Relapsed or Metastatic Triple Receptor Negative Breast Cancer (NCT03692689)Sinocelltech Ltd.2018-07-20
Safety and Efficacy of SGN-LIV1A Plus Pembrolizumab for Patients With Locally-Advanced or Metastatic Triple-Negative Breast Cancer (NCT03310957)Seagen Inc.2018-02-27
Study of Boserolimab (MK-5890) as Monotherapy and in Combination With Pembrolizumab (MK-3475) in Adults With Advanced Solid Tumors (MK-5890-001) (NCT03396445)Merck Sharp & Dohme LLC2018-02-18
Study of Pembrolizumab and Mifepristone in Patients With Advanced HER2-negative Breast Cancer (NCT03225547)University of Chicago2018-02-12
A Study of AK-01 (LY3295668) in Solid Tumors (NCT03092934)Eli Lilly and Company2017-05-29
Window of Opportunity Trial of Dasatinib in Operable Triple Negative Breast Cancers With nEGFR (NCT02720185)University of Wisconsin, Madison2017-05-03
Study of Pembrolizumab (MK-3475) Plus Chemotherapy vs Placebo Plus Chemotherapy as Neoadjuvant Therapy and Pembrolizumab vs Placebo as Adjuvant Therapy in Participants With Triple Negative Breast Cancer (TNBC) (MK-3475-522/KEYNOTE-522) (NCT03036488)Merck Sharp & Dohme LLC2017-03-07
Trilaciclib (G1T28), a CDK 4/6 Inhibitor, in Combination With Gemcitabine and Carboplatin in Metastatic Triple Negative Breast Cancer (mTNBC) (NCT02978716)G1 Therapeutics, Inc.2017-02-02
Assessing the Efficacy of Paclitaxel and Olaparib in Comparison to Paclitaxel / Carboplatin Followed by Epirubicin/Cyclophosphamide as Neoadjuvant Chemotherapy in Patients With HER2-negative Early Breast Cancer and Homologous Recombination Deficiency (NCT02789332)GBG Forschungs GmbH2016-09-01
Adjuvant Treatment for High-risk Triple Negative Breast Cancer Patients With the Anti-PD-l1 Antibody Avelumab (NCT02926196)Istituto Oncologico Veneto IRCCS2016-06-17
Durvalumab and Tremelimumab in Combination With First-Line Chemotherapy in Advanced Solid Tumors (NCT02658214)AstraZeneca2016-04-28
A Study of Neoadjuvant Paclitaxel in Combination With Bavituximab in Early- Stage Triple- Negative Breast Cancer (NCT02685306)Peregrine Pharmaceuticals2016-03-01
Safety and Efficacy Study of Pembrolizumab (MK-3475) in Combination With Chemotherapy as Neoadjuvant Treatment for Participants With Triple Negative Breast Cancer (TNBC) (MK-3475-173/KEYNOTE-173) (NCT02622074)Merck Sharp & Dohme LLC2016-01-27
The Clinical Significance of Cellular Immune Adjuvant Therapy of Triple Negative Breast Cancer (NCT02539017)First Affiliated Hospital Xi'an Jiaotong University2015-11-01
Safety and Immunogenicity of a Personalized Synthetic Long Peptide Breast Cancer Vaccine Strategy in Patients With Persistent Triple-Negative Breast Cancer Following Neoadjuvant Chemotherapy (NCT02427581)Washington University School of Medicine2015-09-29
Safety and Immunogenicity of a Personalized Polyepitope DNA Vaccine Strategy in Breast Cancer Patients With Persistent Triple-Negative Disease Following Neoadjuvant Chemotherapy (NCT02348320)Washington University School of Medicine2015-06-17
A Study Evaluating PF-03084014 In Patients With Advanced Breast Cancer With Or Without Notch Alterations (NCT02299635)Pfizer2015-02-03
Neoadjuvant Treatment of Triple Negative Breast Cancer Patients With Docetaxel and Carboplatin to Assess Anti-tumor Activity (NCT02124902)Washington University School of Medicine2014-07-07
A Safety Study of SGN-LIV1A in Breast Cancer Patients (NCT01969643)Seagen Inc.2013-10-22
Triple-negative Breast Cancer: a New Perspective on Biomarkers (NCT03539965)Instituto Nacional de Cancer, Brazil2010-01-01

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