| Stanford Accelerated Intelligent Neuromodulation Therapy for Treatment-Resistant Depression (SAINT-TRD) (NCT03068715) | Stanford University | 2017-03-20 |
| Optimizing Outcomes of Treatment-Resistant Depression in Older Adults (NCT02960763) | Washington University School of Medicine | 2017-02-24 |
| PINS Stimulator System for Patients With Treatment Resistant Depression (NCT02253355) | Beijing Pins Medical Co., Ltd | 2016-12-01 |
| Effects of TBS on 5-HT1A Receptor Binding (NCT02810717) | Rupert Lanzenberger | 2016-12-01 |
| The UTHealth Ketamine Project (NCT02882711) | The University of Texas Health Science Center, Houston | 2016-11-07 |
| Low Dose Intravenous Ketamine in Treatment Resistant Depression Patients (NCT02935595) | The University of Texas Health Science Center, Houston | 2016-10-14 |
| Neurocognitive Features of Patients With Treatment-Resistant Depression (NCT03134066) | Massachusetts General Hospital | 2016-09-01 |
| Structural and Functional Connectivity of Brainstem Monoamine Pathways in Treatment Resistant Depression (NCT03109717) | Kathryn O'Connor | 2016-07-01 |
| D-cycloserine for Relapse Prevention Following Intravenous Ketamine in Treatment-resistant Depression (NCT02772211) | Sheba Medical Center | 2016-06-01 |
| Long Term Follow-up of Deep Brain Stimulation for Treatment-Resistant Depression (NCT03360942) | Dartmouth-Hitchcock Medical Center | 2016-04-18 |
| Treatment Resistant Depression and Insomnia in Older Veterans (NCT02971150) | VA Pittsburgh Healthcare System | 2016-04-01 |
| A Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant Depression (NCT02497287) | Janssen Research & Development, LLC | 2015-09-30 |
| A Study to Evaluate the Efficacy, Safety, and Tolerability of Fixed Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression (NCT02417064) | Janssen Research & Development, LLC | 2015-08-10 |
| A Study to Evaluate the Efficacy, Safety, and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression (NCT02418585) | Janssen Research & Development, LLC | 2015-08-07 |
| Administration of Subanesthetic Dose of Ketamine and Electroconvulsive Treatment for Treatment Resistant Depression (NCT02522377) | The Cleveland Clinic | 2015-08-01 |
| Efficacy of Repeated Ketamine Infusions for Treatment-resistant Depression (NCT02360280) | VA Office of Research and Development | 2015-04-01 |
| Double-Blind, Placebo-Controlled Trial of Ketamine Therapy in Treatment-Resistant Depression (TRD) (NCT01920555) | Massachusetts General Hospital | 2014-12-01 |
| Implementation Trial of Evidence Based Practices for Mood Disorders (NCT02150577) | University of Arkansas | 2014-05-01 |
| Deep Brain Stimulation (DBS) Therapy for Treatment Resistant Depression (NCT02046330) | The University of Texas Health Science Center, Houston | 2013-12-16 |
| Proof-of-Concept Trial of CERC-501 Augmentation of Antidepressant Therapy in Treatment-Resistant Depression (NCT01913535) | Massachusetts General Hospital | 2013-09-12 |
| Comparing Ketamine and Propofol Anesthesia for Electroconvulsive Therapy (NCT01935115) | University of Saskatchewan | 2013-09-01 |
| Deep Brain Stimulation for Treatment Resistant Depression With the Medtronic Activa PC+S (NCT01984710) | Emory University | 2013-09-01 |
| Focal Electrically Administered Seizure Therapy for the Treatment of Depression (NCT02462551) | Ziad Nahas | 2013-09-01 |
| Low Field Magnetic Stimulation for Treatment Resistant Depression (NCT01944644) | Weill Medical College of Cornell University | 2013-08-01 |
| Deep Brain Stimulation (DBS) for Treatment-Resistant Depression (TRD) (NCT01898429) | Paul Holtzheimer | 2013-07-01 |
| Action of Ketamine in Treatment-Resistant Depression (NCT01945047) | University of Ottawa | 2013-05-01 |
| Trial of Low Field Magnetic Stimulation Augmentation of Antidepressant Therapy in Treatment-Resistant Depression (NCT01654796) | Massachusetts General Hospital | 2013-04-01 |
| Interpersonal Psychotherapy for Treatment Resistant Depression (NCT01896349) | Hospital de Clinicas de Porto Alegre | 2013-04-01 |
| An Open Label Study of Clinical Utility and Patient Outcomes of the Genecept Assay (NCT01507155) | Genomind, LLC | 2013-04-01 |
| Coupling Repetitive Transcranial Magnetic Stimulation With a Neuronavigation System in Treatment Resistant Depression (NCT01677078) | Rennes University Hospital | 2013-01-21 |
| A Study of Olanzapine and Fluoxetine for Treatment-resistant Depression (NCT01687478) | Eli Lilly and Company | 2012-09-01 |
| Functional and Neurochemical Correlates of Treatment Response in Major Depressive Disorder (NCT01598324) | Mclean Hospital | 2012-07-01 |
| Exercise in Treatment Resistant Depression (TRD): A Feasibility Study (NCT01383811) | Milton S. Hershey Medical Center | 2011-06-01 |
| Pulsating ElectroMagnetive Treatment (PEMF) at Treatment Resistant Depression (NCT01353092) | Hillerod Hospital, Denmark | 2011-04-01 |
| Efficacy, Safety and Tolerability of CX157 in Treatment Resistant Depression (NCT01246908) | CeNeRx BioPharma Inc. | 2010-11-01 |
| A Study in Relapse Prevention of Treatment-Resistant Depression (NCT00958568) | Eli Lilly and Company | 2009-08-01 |
| A Pilot Study of the Use of Magnetic Seizure Therapy for Depression (NCT00808938) | Bayside Health | 2009-01-01 |
| Comparing Quetiapine XR Monotherapy and Augmentation With Lithium Augmentation in TRD Patients (NCT00789854) | AstraZeneca | 2008-11-01 |
| Ketamine Frequency Treatment for Major Depressive Disorder (NCT00646087) | Essentia Health | 2008-03-01 |
| Epidural Cortical Stimulation for Depression (NCT00565617) | Medical University of South Carolina | 2007-10-01 |
| Berlin Deep Brain Stimulation Depression Study (NCT00531726) | Charite University, Berlin, Germany | 2007-09-01 |
| Deep Brain Stimulation in Treatment Resistant Depression (NCT01435148) | North Bristol NHS Trust | 2006-12-01 |
| Risperidone (Risperdal) Augmentation in Depressed Partial Responders to SRI Treatment (NCT00178854) | Vanderbilt University Medical Center | 2004-05-01 |