| Study of PLK1 Inhibitor, Onvansertib, in Relapsed Small Cell Lung Cancer (NCT05450965) | University of Maryland, Baltimore | 2022-07-19 |
| A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain (NCT05419076) | Memorial Sloan Kettering Cancer Center | 2022-06-10 |
| Pembrolizumab/Vibostolimab (MK-7684A) or Atezolizumab in Combination With Chemotherapy in First Line Treatment of Extensive-Stage Small Cell Lung Cancer (MK-7684A-008/KEYVIBE-008) (NCT05224141) | Merck Sharp & Dohme LLC | 2022-03-24 |
| KRT-232 in Subjects With Relapsed or Refractory Small Cell Lung Cancer (NCT05027867) | Kartos Therapeutics, Inc. | 2021-12-06 |
| Surufatinib Combined With Chemotherapy Plus Toripalimab or Not in the Treatment of Small Cell Lung Cancer (NCT04996771) | Sun Yat-sen University | 2021-11-09 |
| Safety and Efficacy Study of Investigational Agents as Monotherapy or in Combination With Pembrolizumab (MK-3475) for the Treatment of Extensive-Stage Small Cell Lung Cancer (ES-SCLC) in Need of Second-Line Therapy (MK-3475-B98/KEYNOTE-B98) (NCT04938817) | Merck Sharp & Dohme LLC | 2021-08-19 |
| Camrelizumab Plus Apatinib as Maintenance Therapy in Extensive-stage Small-cell Lung Cancer (NCT04901754) | Henan Cancer Hospital | 2021-07-14 |
| Searching for Predictive Biomarkers of Efficacy in Small Cell Lung Cancer Patients Treated With Chemotherapy-immunotherapy Combination Using Imaging Mass Cytometry (HYPE) (NCT06558903) | University Hospital, Brest | 2021-06-24 |
| Study of CBX-12 in Subjects With Advanced or Metastatic Refractory Solid Tumors (NCT04902872) | Cybrexa Therapeutics | 2021-05-03 |
| A Phase Ib/III Clinical Study to Evaluate the Efficacy and Safety of IBI318 in Combination With Paclitaxel Versus Placebo in Combination With Paclitaxel in Patients With Small Cell Lung Cancer Who Have Failed First-line or Above Chemotherapies (NCT04672928) | Innovent Biologics (Suzhou) Co. Ltd. | 2020-12-14 |
| Tislelizumab in Combination With Anlotinib With ES-SCLC as Maintenance Therapy After First Line Chemotherapy (NCT04620837) | Chinese Academy of Medical Sciences | 2020-11-01 |
| The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE) (NCT04585750) | PMV Pharmaceuticals, Inc | 2020-10-29 |
| A Study of Durvalumab Plus Tremelimumab With Chemotherapy in Untreated ES-SCLC (NCT03963414) | University of Nebraska | 2020-09-25 |
| Lurbinectedin (PM01183) Combined With Pembrolizumab in Small Cell Lung Cancer. (NCT04358237) | Antonio Calles Blanco | 2020-09-21 |
| A Study of Sequential Therapy of Camrelizumab Combined With Chemotherapy（Irinotecan Plus Platinum）and With Apatinib in Participants With Untreated Advanced Small Cell Lung Cancer（SCLC） (NCT04453930) | Peking Union Medical College Hospital | 2020-06-08 |
| First-line Chemotherapy Followed by Toripalimab Combined With Anlotinib for Maintenance in ES-SCLC (NCT04363255) | Taizhou Hospital | 2020-05-01 |
| Endobronchial Ultrasound Guided Interstitial Photodynamic Therapy in Treating Patients With Locally Advanced Lung Cancer (NCT03735095) | Roswell Park Cancer Institute | 2020-02-12 |
| Feasibility and Safety Study of Nivolumab With Irinotecan for Small Cell Lung Cancer (NCT04173325) | Augusta University | 2020-01-06 |
| PET/CT Imaging of Small Cell Lung Cancer Using 89Zr-DFO-SC16.56 (NCT04199741) | Memorial Sloan Kettering Cancer Center | 2019-12-11 |
| Assessing Safety and Efficacy of Sintilimab and Metformin Combination Therapy in SCLC (NCT03994744) | Hunan Cancer Hospital | 2019-08-20 |
| A Study of Atezolizumab in Combination With Carboplatin Plus Etoposide to Investigate Safety and Efficacy in Patients With Untreated Extensive-Stage Small Cell Lung Cancer (NCT04028050) | Hoffmann-La Roche | 2019-08-12 |
| A Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid Tumors (NCT03849469) | Xencor, Inc. | 2019-05-29 |
| A Safety, Tolerability and Preliminary Efficacy Evaluation of CC-90011 Given in Combination With Cisplatin and Etoposide in Subjects With First Line, Extensive Stage Small Cell Lung Cancer (NCT03850067) | Celgene | 2019-03-12 |
| A Study of Lobaplatin/Etoposide With or Without Anlotinib Maintenance Therapy in Patients With ES-SCLC (NCT03700359) | The First Affiliated Hospital of Guangzhou Medical University | 2019-03-01 |
| Subsequent Line Gemcitabine and Nivolumab in Treating Participants With Metastatic Small Cell Lung Cancer (NCT03662074) | Wake Forest University Health Sciences | 2018-11-07 |
| Immunotherapy in Combination With Chemotherapy in Small-cell Lung Cancer (NCT03568097) | Hellenic Cooperative Oncology Group | 2018-09-16 |
| A Study of Olaparib and Low Dose Radiotherapy for Small Cell Lung Cancer (NCT03532880) | Memorial Sloan Kettering Cancer Center | 2018-07-12 |
| A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors (NCT03517488) | Xencor, Inc. | 2018-07-10 |
| A Mobile Supportive Care App for Patients With Metastatic Lung Cancer (NCT03512015) | Bocconi University | 2018-05-15 |
| Immunotherapy in Combination With Chemoradiation in Patients With Advanced Solid Tumors (NCT03509012) | AstraZeneca | 2018-05-02 |
| Bronchoscopy With Bronchoalveolar Lavage in Identifying Biomarkers of Response to Immune Checkpoint Inhibitors in Patients With Non-small Cell or Small Cell Lung Cancer (NCT02937402) | Vanderbilt-Ingram Cancer Center | 2018-04-05 |
| Study Evaluating Safety, Tolerability and Pharmacokinetics (PK) of Tarlatamab in Adults With Small Cell Lung Cancer (SCLC) (NCT03319940) | Amgen | 2017-12-26 |
| A Study of Atezolizumab (Tecentriq®) in Ministry of Food and Drug Safety (MFDS)-Approved Indication(s) (NCT03232593) | Hoffmann-La Roche | 2017-11-29 |
| Phase II Study of Afatinib as Third- or Further-line Treatment for Patients With Stage IV Bronchial Adenocarcinoma, Harboring Wild-type EGFR, Expressing the Neurotensin - Neurotensin Receptor Complex (NCT02876081) | Fondation Hôpital Saint-Joseph | 2017-09-01 |
| PEN-866 in Patients With Advanced Solid Malignancies (NCT03221400) | Tarveda Therapeutics | 2017-08-29 |
| A Study of AK-01 (LY3295668) in Solid Tumors (NCT03092934) | Eli Lilly and Company | 2017-05-29 |
| A Study of Carboplatin Plus Etoposide With or Without Atezolizumab in Participants With Untreated Extensive-Stage (ES) Small Cell Lung Cancer (SCLC) (NCT02763579) | Hoffmann-La Roche | 2016-06-07 |
| Durvalumab and Tremelimumab in Combination With First-Line Chemotherapy in Advanced Solid Tumors (NCT02658214) | AstraZeneca | 2016-04-28 |
| Molecular Analysis and Treatment Options of SCLC (NCT05945745) | Shanghai Chest Hospital | 2016-01-01 |
| Study of Pembrolizumab (MK-3475) in Participants With Advanced Solid Tumors (MK-3475-158/KEYNOTE-158) (NCT02628067) | Merck Sharp & Dohme LLC | 2015-12-18 |
| Trial of Topotecan With VX-970 (M6620), an ATR Kinase Inhibitor, in Small Cell Cancers and Extrapulmonary Small Cell Cancers (NCT02487095) | National Cancer Institute (NCI) | 2015-07-30 |
| Phase I Trial Of IMRT Using A Contralateral Esophagus Sparing Technique (CEST) In Locally Advanced Lung Cancer (NCT02394548) | Massachusetts General Hospital | 2015-06-01 |
| Memory Preservation of Prophylactic Cranial Irradiation With Hippocampal Avoidance (PREMER-TRIAL) (NCT02397733) | Grupo de Investigación Clínica en Oncología Radioterapia | 2014-09-01 |
| RONICICLIB / Placebo in Combination With Chemotherapy in Small Cell Lung Cancer (NCT02161419) | Bayer | 2014-07-30 |
| Two Schedules of Hyperfractionated Thoracic Radiotherapy in Limited Disease Small Cell Lung Cancer (NCT02041845) | Norwegian University of Science and Technology | 2014-07-08 |
| Doxepin Hydrochloride in Treating Esophageal Pain in Patients With Thoracic Cancer Receiving Radiation Therapy to the Thorax With or Without Chemotherapy (NCT02062632) | Mayo Clinic | 2014-04-14 |
| Two Different Dosages of Irinotecan Combined With Cisplatin Scheme in Extensive Disease-Small Cell Lung Cancer (NCT01977235) | Third Military Medical University | 2013-09-01 |
| Clinical Study to Evaluate the Maximum Tolerated Dose of BAY1000394 When Given Together With Chemotherapy and the Effectiveness of This Combination Treatment in Shrinking a Specific Type of Lung Tumors (Small Cell Lung Cancer) (NCT01573338) | Bayer | 2013-02-25 |
| Trial in Extensive-Disease Small Cell Lung Cancer (ED-SCLC) Subjects Comparing Ipilimumab Plus Etoposide and Platinum Therapy to Etoposide and Platinum Therapy Alone (NCT01450761) | Bristol-Myers Squibb | 2011-12-13 |
| Irinotecan/Cisplatin With or Without Simvastatin in Chemo-naive Patients With Extensive Disease-small Cell Lung Cancer (NCT01441349) | National Cancer Center, Korea | 2011-08-01 |
| A Phase 2, Open-Label Study of Amuvatinib in Combination With Platinum-Etoposide Chemotherapy in Small Cell Lung Cancer (NCT01357395) | Astex Pharmaceuticals, Inc. | 2011-05-01 |
| Study of Talazoparib, a PARP Inhibitor, in Patients With Advanced or Recurrent Solid Tumors (NCT01286987) | Pfizer | 2011-01-03 |
| Effect of Chemotherapy With Paclitaxel/Cisplatin on Development Dysgeusia in Non Small Cell Lung Cancer (NCT01540045) | Instituto Nacional de Cancerologia de Mexico | 2010-12-01 |
| Collaborative Advanced Stage Tissue Lung Cancer (CASTLE) Network (NCT01574300) | Addario Lung Cancer Medical Institute | 2010-11-01 |
| Determination of Safety, Efficacy, and Pharmacokinetics of "Regorafenib" Combined With Pemetrexed and Cisplatin in Patients With Nonsquamous Non-Small Cell Lung Cancer (NCT01187615) | Bayer | 2010-08-01 |
| A Study Of Cisplatin (Or Carboplatin) And Etoposide With Or Without Figitumumab (CP-751,871) In Patients With Extensive-Stage Small Cell Lung Cancer (NCT00977561) | Pfizer | 2010-04-01 |
| A Study of BMS-833923 With Carboplatin and Etoposide Followed by BMS-833923 Alone in Subjects With Extensive-Stage Small Cell Lung Cancer (NCT00927875) | Bristol-Myers Squibb | 2010-02-01 |
| A Phase I Study of Belinostat in Combination With Cisplatin and Etoposide in Adults With Small Cell Lung Carcinoma and Other Advanced Cancers (NCT00926640) | National Cancer Institute (NCI) | 2009-07-01 |
| A Phase II Study of Doxorubicin, Cyclophosphamide and Vindesine With Valproic Acid in Patients With Refractory or Relapsing Small Cell Lung Cancer After Platinum Derivatives and Etoposide (NCT00759824) | European Lung Cancer Working Party | 2008-09-01 |
| LBH Phase II in Small Cell Lung Cancer (SCLC) (NCT01222936) | Southern Europe New Drug Organization | 2008-05-01 |
| A Phase 1/2a Study of ABT-263 in Subjects With Small Cell Lung Cancer (SCLC) or Other Non-Hematological Malignancies (NCT00445198) | AbbVie (prior sponsor, Abbott) | 2007-04-01 |
| Study Of Irinotecan Hydrochloride (Campto(R)) And Cisplatin Versus Etoposide And Cisplatin In Small Cell Lung Cancer (NCT00143455) | Pfizer | 2002-06-01 |
| Oral Green Tea Extract for Small Cell Lung Cancer (NCT01317953) | Shandong Cancer Hospital and Institute | |
| Managed Access Program Cohort Treatment Plan CTMT212X2002I to Provide Access to Trametinib and Dabrafenib Combination Therapy for Patients With BRAF V600 Mutation-positive Advanced Non-Small Cell Lung Cancer (NCT04507919) | Novartis Pharmaceuticals | |