| Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensive Care Unit Adult Patients (INSPiRE-ICU2) (NCT05327296) | Sedana Medical | 2022-06-30 |
| Efficacy and Safety of Inhaled Isoflurane Delivered Via the Sedaconda ACD-S Compared to Intravenous Propofol for Sedation of Mechanically Ventilated Intensive Care Unit Adult Patients (INSPiRE-ICU1) (NCT05312385) | Sedana Medical | 2022-04-28 |
| A Pooled Analysis of Long-Term Outcomes After Inhaled Isoflurane Via the Sedaconda ACD-S Compared to Intravenous Propofol (NCT06809218) | Sedana Medical | 2022-04-22 |
| Sedation With Remimazolam During Spinal Anesthesia (NCT05305248) | Gangnam Severance Hospital | 2022-04-19 |
| Gastro-laryngeal Tube During Transesophageal Echocardiography (NCT05272306) | Bezmialem Vakif University | 2022-04-13 |
| RemImazolam Besylate for ICU-sedation in Patients With Mechanical Ventilation After Oral and Maxillofacial Surgery (NCT05606315) | Nanfang Hospital, Southern Medical University | 2022-03-16 |
| Endoscopic Hemostatic and Sedative Treatment of Esophageal and Gastric Variceal Bleeding (NCT05554965) | Renmin Hospital of Wuhan University | 2022-02-10 |
| Dexmedetomidine Versus Ketofol for Moderate Sedation in Endoscopic Retrograde Cholangiopancreatography (NCT06212401) | Sindh Institute of Urology and Transplantation | 2021-12-01 |
| Comparison of Oral Chloral Hydrate and Combination of Intranasal Dexmedetomidine and Ketamine for Procedural Sedation in Children (NCT04820205) | Seoul National University Hospital | 2021-10-29 |
| Adjuvant Continuous Infusion of Nefopam Versus Standard of Care in Mechanically Ventilated Critically Ill Patients: Randomized Double-blind Controlled Study (NCT05071352) | Cairo University | 2021-10-01 |
| Dexmedetomidine Versus Ketamine Loading for Dexmedetomidine Sedation During Elective Cesarean Section Under Spinal Anesthesia (NCT07676955) | Haseki Training and Research Hospital | 2021-06-01 |
| A Randomized Single-blind Clinical Trial of the Efficacy and Safety of Remimazolam in Painless Bronchoscopy (NCT04919174) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2021-04-23 |
| Effects of NIV and CPAP on Ventilation Distribution, Measured by EIT, During Deep Sedation in Paediatric Patients (NCT05495477) | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 2021-04-20 |
| Remimazolam for Sedation in ICU Patients Undergoing Mechanical Ventilation (NCT04815265) | Tianjin Nankai Hospital | 2021-04-01 |
| Dexmedetomidine Versus Propofol for Sedation During Awake Endotracheal Intubation (NCT04753515) | Sixth Affiliated Hospital, Sun Yat-sen University | 2021-03-05 |
| Effect & Safety of Inhaled Isoflurane vs IV Midazolam for Sedation in Mechanically Ventilated Children 3-17 Years Old (NCT04684238) | Sedana Medical | 2021-01-14 |
| Propranolol as an Anxiolytic to Reduce the Use of Sedatives From Critically-ill Adults Receiving Mechanical Ventilation (NCT04467086) | Ottawa Hospital Research Institute | 2021-01-08 |
| Pre-emptive Pregabalin on Attenuating Maternal Anxiety And Stress Response To Intubation During Caesarean Section (NCT04622202) | Zagazig University | 2020-11-15 |
| End-Tidal Carbon Dioxide Monitoring Device for Sedation During Endoscopic Ultrasonography (NCT04549623) | Changhai Hospital | 2020-09-27 |
| The Effect of Music on Delirium, Pain, Need of Sedation, Anxiety and Vital Parameters (NCT05082623) | Ege University | 2020-09-14 |
| Sedation and Ventilator Weaning Protocol in PICU (NCT04788589) | Indonesia University | 2020-09-01 |
| Intravenous Infusion of Lidocaine in Gastroscopy (NCT04439773) | Shandong University | 2020-07-01 |
| Intravenous Infusion of Lidocaine in Colonoscopy (NCT04439786) | Shandong University | 2020-07-01 |
| Inhaled Sedation in COVID-19-related Acute Respiratory Distress Syndrome (ISCA): an International Research Data Study in the Recent Context of Widespread Disease Resulting From the 2019 (SARS-CoV2) Coronavirus Pandemics (COVID-19) (NCT04383730) | University Hospital, Clermont-Ferrand | 2020-06-26 |
| A Clinical Study of Remimazolam Tosilate in Patients Undergoing Bronchoscopy (NCT04400201) | Jiangsu HengRui Medicine Co., Ltd. | 2020-06-15 |
| A Study Evaluating the Mass Balance of Micro-dose[14C]HSK3486 Emulsion Injection in Healthy Adults (NCT03751969) | Sichuan Haisco Pharmaceutical Group Co., Ltd | 2020-03-30 |
| LEGO MRI: Decreasing the Need for Sedation, and Improving Patient Anxiety. (NCT04172909) | Montefiore Medical Center | 2020-02-24 |
| Controlled Sedoanalgesia in External DCR Surgery (NCT05397301) | Turkish Society of Anesthesiology and Reanimation | 2020-02-07 |
| Risk Factors for Prolonged Invasive Mechanical Ventilation in COVID-19 Acute Respiratory Distress Syndrome (NCT04411459) | Azienda Usl di Bologna | 2020-02-01 |
| Dexmedetomidine Sedation in Orthopedic Surgery (NCT04149626) | Asklepieion Voulas General Hospital | 2020-01-29 |
| A Study Evaluating the Efficacy and Safety of HSK3486 for Sedation (NCT04147416) | Sichuan Haisco Pharmaceutical Group Co., Ltd | 2019-11-22 |
| The Use of Ketamine and Dexmedetomidine in Intensive Care Sedation (NCT04096768) | Lebanese American University Medical Center | 2019-09-16 |
| Analgosedative adjuncT keTAmine Infusion iN Mechanically vENTilated ICU Patients (NCT04075006) | King Faisal Specialist Hospital & Research Center | 2019-08-28 |
| Precedex Special Investigation (in Pediatric Patients) (NCT04040439) | Pfizer | 2019-07-30 |
| Incidence OIRD Medical and Trauma Patients (NCT03948880) | Community Health System | 2019-07-29 |
| The Deep Sedation for Ablation Study (NCT03844841) | Insel Gruppe AG, University Hospital Bern | 2019-07-01 |
| Sedation Strategies for Therapeutic Bronchoscopy 2 (NCT03983915) | Changhai Hospital | 2019-06-17 |
| Sedation Strategies for Diagnostic Bronchoscopy 2 (NCT03983889) | Changhai Hospital | 2019-06-17 |
| Comparison of Two Sedation Versus Placebo Techniques During Cataract Surgery Under Local Anesthesia (NCT04149340) | University of Liege | 2019-06-01 |
| Intravenous Infusion of Lidocaine in ERCP (NCT03996577) | Shandong University | 2019-05-15 |
| High-Flow Nasal Oxygenation Versus Standard Oxygenation in Gastrointestinal Endoscopy With Sedation. (NCT03829293) | Centre Hospitalier Régional d'Orléans | 2019-03-26 |
| A Study Evaluating the Safety and Pharmacokinetics/Pharmacodynamics of HSK3486 (NCT03745625) | Sichuan Haisco Pharmaceutical Group Co., Ltd | 2019-01-09 |
| A Study Evaluating the Mass Balance of [14C]HSK3486 Emulsion Injection in Healthy Adults. (NCT03751956) | Sichuan Haisco Pharmaceutical Group Co., Ltd | 2019-01-06 |
| Automated Postoperative Sedation After Cardiac Surgery (NCT03517735) | CMC Ambroise Paré | 2018-12-17 |
| A Study Evaluating Drug-Drug Interaction (DDI) Between HSK3486 Injectable Emulsion and Rifampin Capsules (NCT03758469) | Sichuan Haisco Pharmaceutical Group Co., Ltd | 2018-12-14 |
| Intranasal Dexmedetomidine for Procedural Pain Management in Elderly Adults in Palliative Care (NCT03151863) | Walid HABRE | 2018-11-14 |
| Intranasal Dexmedetomidine Sedation in Children for Non-painful Procedures (NCT03220880) | Columbia University | 2018-09-04 |
| Incidence of Opioid-Induced Respiratory Depression in Medical and Trauma Patients (NCT03647696) | Poudre Valley Health System | 2018-08-30 |
| Study of Remimazolam Tosilate in Patients Undergoing Colonoscopy (NCT03779061) | Jiangsu HengRui Medicine Co., Ltd. | 2018-06-28 |
| Assessment of Analgesia, Sedation, Physical Restraints and Delirium in Spanish Intensive Care Units (NCT03773874) | Hospital Universitario Getafe | 2018-02-12 |
| Sedation MRI - Propofol Versus Propofol-Ketamin in Children (NCT01519154) | Achim Schmitz | 2018-02-09 |
| Sedation Of Adult Patients Undergoing Gastrointestinal Endoscopy: A Network Meta-analysis (NCT03632330) | Pfizer | 2018-02-05 |
| Sedation Strategies for Therapeutic Bronchoscopy (NCT03406546) | Changhai Hospital | 2018-02-01 |
| Sedation Strategies for Diagnostic Bronchoscopy (NCT03406533) | Changhai Hospital | 2018-02-01 |
| Effect of Midazolam and Dexmedetomidine on Heart Function - A Randomized MRI-based Study. (NCT04529187) | Masaryk Hospital Krajská zdravotní a.s. | 2018-01-01 |
| Safety and Efficacy of Sufentanil Combined With Midazolam in Bronchoscopy Under Conscious Sedation: Retrospective Study (NCT03890094) | Guangzhou Institute of Respiratory Disease | 2018-01-01 |
| Deep Brain Stimulation (DBS) Sedation (NCT03283150) | University of Wisconsin, Madison | 2017-12-01 |
| Comparison of Intravenous V/S Nasal Atomizer Delivery of Midazolam for Conscious Sedation for No-scalpel Vasectomy (NCT06449365) | University of Tennessee Graduate School of Medicine | 2017-10-22 |
| Oral Versus Intravenous Sedation for Ocular Procedures (NCT03246724) | Boston Medical Center | 2017-10-16 |
| Cerebral Vascular Effects of Dexmedetomidine Versus Propofol Sedation in Intubated Mechanically Ventilated ICU Patients (NCT03285165) | Assiut University | 2017-09-14 |
| Study of Remimazolam Tosilate in Patients Undergoing Diagnostic Upper GI Endoscopy (NCT03425474) | Jiangsu HengRui Medicine Co., Ltd. | 2017-09-01 |
| Sedation During Pediatric Diagnostic Gastrointestinal Endoscopy Gastrointestinal Endoscopy (NCT03235609) | Assiut University | 2017-08-16 |
| Sedation Practices and Preferences of Turkish Intensive Care Physicians: National Survey (NCT03488069) | Istanbul University | 2017-08-02 |
| Safety, Pharmacokinetics and Pharmacodynamics of Intranasal Dexmedetomidine in Healthy Subjects (NCT03293277) | Jiangsu HengRui Medicine Co., Ltd. | 2017-07-26 |
| Sedation of Advanced Endoscopic Procedure (NCT03172078) | National Taiwan University Hospital | 2017-06-05 |
| Pharmacokinetics and Pharmacodynamics of Oral Transmucosal Dexmedetomidine. (NCT03120247) | Assiut University | 2017-04-05 |
| The Effects of Different Anesthetics on Functional Connectivity (NCT03343873) | Beijing Tiantan Hospital | 2017-04-01 |
| Dexmedetomidine Versus Propofol in Conjunction With Regional Block for Shoulder Arthroscopy (NCT03775876) | Saint-Joseph University | 2017-03-01 |
| Sedation Using Virtual Reality During Surgery Under Spinal Anesthesia (NCT03055663) | Seoul National University Hospital | 2017-02-20 |
| Dexmedetomidine vs Midazolam on Resting Energy Expenditure in Critically Ill Patients (NCT03030911) | Cairo University | 2017-01-01 |
| The Use of Capnography and Integrated Pulmonary Index in the Electrophysiology Laboratory (NCT03025490) | Hadassah Medical Organization | 2017-01-01 |
| Safety And Efficacy Of Dexmedetomidine Sedation In Intubated Mechanically Ventilated Infants With Respiratory Failure (NCT02996058) | Assiut University | 2016-12-01 |
| A Study Evaluating Safety, Pharmacodynamics and Pharmacokinetics of HSK3486 and Etomidate for Induction of Anesthesia in Healthy Male Subjects (NCT04054063) | Sichuan Haisco Pharmaceutical Group Co., Ltd | 2016-11-30 |
| A Study of Remimazolam Tosilate in Patients Undergoing Diagnostic Upper GI Endoscopy (NCT03003884) | Jiangsu HengRui Medicine Co., Ltd. | 2016-11-01 |
| Bispectral Index(BIS) on Depth of Sedation With Dexmedetomidine, Propofol and Midazolam During Spinal Anesthesia (NCT03399019) | Hallym University Medical Center | 2016-09-05 |
| Patient-controlled Sedation With Propofol During Cataract Surgery Under Topical Anesthesia (NCT02771912) | Fondation Ophtalmologique Adolphe de Rothschild | 2016-07-01 |
| A Study Evaluating Safety, Tolerability, and Pharmacokinetics/Pharmacodynamics of Single IV Dose of HSK3486 Injectable Emulsion in Healthy Subjects. (NCT03773835) | Sichuan Haisco Pharmaceutical Group Co., Ltd | 2016-05-01 |
| The Effect of Continuous Femoral Nerve Block With Modulation of Depth of Anesthesia on Prognosis of Patients Receiving Total Knee Arthroplasty (NCT02576015) | Min Su | 2016-03-01 |
| The Million Anesthesia Cases Study (MACS) - a Cohort Study of Preoperative Fasting and Perioperative Outcomes (NCT07022951) | Massachusetts General Hospital | 2016-01-01 |
| Risk Factors of Delirium in Sequential Sedation Patients in Intensive Care Unit (NCT03194360) | West China Hospital | 2015-12-01 |
| A Study Evaluating Pharmacodynamics, Pharmacokinetics, Safety and Tolerability of HSK3486 Single Bolus Dose Followed With a 30 Minute Constant Infusion in Healthy Male Subjects (NCT04029766) | Sichuan Haisco Pharmaceutical Group Co., Ltd | 2015-11-10 |
| Evaluating the Safety, Pharmacodynamics and Pharmacokinetics of HSK3486 in Healthy Female Subjects. (NCT04037657) | Sichuan Haisco Pharmaceutical Group Co., Ltd | 2015-04-22 |
| Pilot Study for Sedation Interruption in Children (NCT02426320) | Davinia Withington | 2015-04-01 |
| Intranasal Midazolam in Children as a Pre-Operative Sedative - Part 2 (NCT02356705) | Jennifer Victory, RN, CCRC | 2015-01-01 |
| Impact of a Nurse Implemented Sedation and Analgesia Algorithm in Surgical Intensive Care Unit (NCT03186521) | University Hospital, Caen | 2014-12-01 |
| A Comparison Between Propofol and Etomidate in Hysteroscopy on Effect of Postoperative Sedation and Cognitive Function in Elderly Patients (NCT02147678) | Shaanxi Provincial People's Hospital | 2014-12-01 |
| Nurse Administered Propofol Sedation vs. Midazolam With Fentanyl-sedation for Flexible Bronchoscopy: A Randomized, Single Blind, Controlled Study of Satisfaction and Safety. (NCT02226328) | Copenhagen University Hospital at Herlev | 2014-11-01 |
| Sedation and Physiological Effects of Intranasal Dexmedetomidine in Severe COPD (NCT02211118) | Dayton VA Medical Center | 2014-10-01 |
| Effects of Sedation on Spinal Anesthesia-induced Maternal Hypotension (NCT02732197) | Van Training and Research Hospital | 2014-08-01 |
| Comparison of Outcomes During MRI Sedation With Midazolam-dexmedetomidine Versus Ketamine-dexmedetomidine (NCT02129426) | University of Louisville | 2014-08-01 |
| Interventional Bronchoscopy Under Noninvasive Ventilation (NCT02289586) | Futian People's Hospital | 2014-07-01 |
| A Study Evaluating the Safety, Pharmacodynamics and Pharmacokinetics of HSK3486 in Healthy Subjects. (NCT04033939) | Sichuan Haisco Pharmaceutical Group Co., Ltd | 2014-04-13 |
| The Role of Melatonin in the Effective Attainment of Sleep Electroencephalograms (EEG) in Children (NCT02195661) | University of Cape Town | 2014-04-01 |
| Propofol Administered by Gastroenterologists by Target Controlled Infusion Pump During Endoscopy (NCT02062177) | Università Vita-Salute San Raffaele | 2014-02-01 |
| Satisfaction With Nurse Administered Propofol Sedation vs. Midazolam With Fentanyl Sedation for Endoscopy (NCT01934088) | Copenhagen University Hospital at Herlev | 2014-01-01 |
| Assessment of Sedation During Endoscopy (NCT01747733) | Helsinki University Central Hospital | 2013-12-01 |
| Dexmedetomidine PKPD Modeling and the Influence of Auditory Stimulation on Dexmedetomidine Effect (NCT01879865) | University Medical Center Groningen | 2013-06-01 |
| Randomized Trial of Diphenhydramine Versus Continued Midazolam in "Difficult-to-sedate" Patients Undergoing Colonoscopy (NCT01769586) | VA Connecticut Healthcare System | 2013-02-01 |
| EUROpean Pain Audit In Neonates (NCT01694745) | Hôpital Armand Trousseau | 2012-10-01 |
| Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care (NCT01431326) | Daniel Benjamin | 2011-11-01 |