| Preventive Effect of Clopidogrel on the Systemic Sclerosis Development Risk (NCT05098704) | University Hospital, Bordeaux | 2022-06-22 |
| MRI for Screening and Monitoring Scleroderma ILD (NCT05204355) | University of Kansas Medical Center | 2022-05-01 |
| Effectiveness of Telerehabilitation on Scleroderma (NCT04563481) | Istanbul University | 2022-05-01 |
| Effectiveness of the EmoLED Medical Device in the Healing of Digital Ulcers in Patients With Scleroderma. (NCT05181644) | Emoled | 2022-04-22 |
| Clinico-biological Collection to Investigate the Physiopathology of Systemic Autoimmune Diseases (NCT05251415) | University Hospital, Toulouse | 2022-04-04 |
| COvid-19 Vaccine Booster in Immunocompromised Rheumatic Diseases (NCT05236491) | Paul R Fortin | 2022-03-09 |
| Rheopheresis for Raynaud's and Digital Ulcers in Systemic Sclerosis (NCT05204784) | Peter Korsten | 2022-02-28 |
| Validity and Reliability of the Turkish Version of HAnDE (NCT06536595) | Gazi University | 2022-02-01 |
| Effectiveness of Bosentan Therapy in Patients With Systemic scleRosis and Progressive Digital ulcEr Disease. (NCT05168215) | Elpen Pharmaceutical Co. Inc. | 2022-01-01 |
| Rituxmab Versus IL-6 in Treating ILD (NCT05963048) | Assiut University | 2021-12-01 |
| Rehabilitation Program in Patients With Scleroderma (NCT05041868) | Centro Universitário Augusto Motta | 2021-10-15 |
| A Study of CD19/BCMA Chimeric Antigen Receptor T Cells Therapy for Patients With Refractory Scleroderma (NCT05085444) | Zhejiang University | 2021-10-08 |
| Sildenafil for Early Pulmonary Vascular Disease in Scleroderma (NCT04797286) | Johns Hopkins University | 2021-09-20 |
| SPIN Self-Management Feasibility Trial With Progression to Full-scale Trial (SPIN-SELF) (NCT04246528) | Lady Davis Institute | 2021-09-15 |
| Upper Extremity Home Exercises in Patients With Scleroderma (NCT05080738) | Pamukkale University | 2021-09-10 |
| RENEW Scleroderma: A Peer-Mentored, Web Intervention for Resilience-based, Energy Management to Enhance Wellbeing and Fatigue (NCT04908943) | University of Michigan | 2021-08-28 |
| Laser Treatment for the Improvement of Scars and Scleroderma (NCT04567537) | Massachusetts General Hospital | 2021-06-02 |
| A Study to Evaluate the Safety and Tolerability of Oral Ixazomib in Scleroderma-related Lung Disease Patients (NCT04837131) | Michael M. Pham | 2021-04-28 |
| Prevalence of Hyperprolactinemia in Systemic Scleroderma (NCT04746313) | University Hospital, Lille | 2021-03-01 |
| Telerehabilitation on Hand-Affected Scleroderma (NCT04684225) | Istanbul University | 2021-01-06 |
| Lung Clearance Index to Identify Scleroderma Patients at Risk for ILD (NCT04535245) | National Jewish Health | 2021-01-04 |
| UVA-1 for Treatment of Skin Tightening and Improvement of Hand Function in Scleroderma (NCT04875078) | University of Utah | 2020-12-12 |
| Feasibility and Preliminary Effects of the Resilience-based, Energy Management to Enhance Wellbeing in Systemic Sclerosis (RENEW) Intervention (NCT04588714) | University of Michigan | 2020-10-27 |
| Upfront Autologous HSCT Versus Immunosuppression in Early Diffuse Cutaneous Systemic Sclerosis (NCT04464434) | UMC Utrecht | 2020-09-17 |
| Rheumatology Patient Registry and Biorepository (NCT04402086) | Yale University | 2020-08-04 |
| The Effect of a Self-Management Program on Individuals With Scleroderma (NCT06095921) | Emirhan Karakuş | 2020-07-15 |
| Cohort of Patients With Systemic Sclerosis Within the Framework of the RESO Reference Centre (NCT04265144) | University Hospital, Bordeaux | 2020-06-08 |
| The Effects of Botulinum Toxin on Oral Aperture in Patients With Scleroderma (NCT04523506) | University of Texas Southwestern Medical Center | 2020-05-08 |
| Evaluation of the Scleroderma Patient-centered Intervention Network COVID-19 Home-isolation Activities Together Program (NCT04335279) | Lady Davis Institute | 2020-04-09 |
| Evaluating Gut Imaging and Stool Biomarkers in Patients With Scleroderma-associated Gastrointestinal Disease (NCT04630782) | Singapore General Hospital | 2020-04-09 |
| Yoga Adjunct for Scleroderma (NCT04491396) | Medical University of South Carolina | 2020-01-08 |
| Hyaluronidase in Treating Oral Microstomia in Patients With Sclerosing Skin Disease (NCT04656704) | Brigham and Women's Hospital | 2020-01-01 |
| Assessment of the Prevalence of Olfactory Disorders in Systemic Scleroderma (NCT04178616) | University Hospital, Lille | 2019-12-31 |
| A Study of FCX-013 Plus Veledimex for the Treatment of Moderate to Severe Localized Scleroderma (Morphea) (NCT03740724) | Castle Creek Biosciences, LLC. | 2019-12-18 |
| Mouth Handicap in Systemic Sclerosis (NCT04273386) | Istanbul University | 2019-12-02 |
| The Effect of Physiotherapy Program in Scleroderma Patients (NCT04179292) | Istanbul University | 2019-11-21 |
| SPIN Self-Management Feasibility Trial (NCT03914781) | Lady Davis Institute | 2019-07-05 |
| Smartphone Mindfulness Meditation for Patients With Rheumatic Diseases (NCT03937856) | Johns Hopkins University | 2019-05-07 |
| Cardiac Assessment by PV Loop in IPAH and Scleroderma PAH (NCT04610788) | Johns Hopkins University | 2019-04-15 |
| Local Injection of Ozone Versus Methylprednisolone Acetate in Carpal Tunnel Syndrome of Scleroderma Patients (NCT03742466) | Assiut University | 2018-11-10 |
| CompRehensive Phenotypic Characterization of Patients With Scleroderma-Associated ILD and PH (NCT03726398) | Franz Rischard, DO | 2018-09-01 |
| Endothelial Biomarkers of Systemic Sclerosis-associated Pulmonary Hypertension (NCT03459716) | Louisiana State University Health Sciences Center in New Orleans | 2018-06-01 |
| The Scleroderma Patient-centered Intervention Network (SPIN) Support Group Leader Education Program Feasibility Trial (NCT03508661) | Lady Davis Institute | 2018-04-18 |
| Scleroderma Patient-centered Intervention Network (SPIN) Hand Program (NCT03419208) | Lady Davis Institute | 2018-03-12 |
| Mindfulness Based Stress Reduction in Rheumatic Diseases (NCT03411057) | Johns Hopkins University | 2018-01-18 |
| Maternal Autoimmune Disease Research Alliance (MADRA) Registry (NCT03276923) | Duke University | 2018-01-01 |
| Functional Luminal Imaging Probe (FLIP) Topography Use in Patients With Scleroderma and Trouble Swallowing (NCT03270722) | Stanford University | 2018-01-01 |
| Optical Elastography of Systemic Sclerosis Skin (NCT02835196) | The University of Texas Health Science Center, Houston | 2017-10-25 |
| Brentuximab Vedotin for Systemic Sclerosis (NCT03222492) | National Institute of Allergy and Infectious Diseases (NIAID) | 2017-09-20 |
| MRI Quantification of Pulmonary Fibrosis in Scleroderma Patients (NCT03207997) | Assistance Publique - Hôpitaux de Paris | 2017-09-18 |
| Scleroderma Patient-centered Intervention Network (SPIN) Hand Program Feasibility Study (NCT03092024) | Lady Davis Institute | 2017-06-01 |
| Transcutaneous Electroacupuncture for Gastric Complications of Scleroderma (NCT03294616) | Johns Hopkins University | 2017-02-06 |
| Effects of Whole Body Vibration Training in Patients With Interstitial Lung Disease (NCT03560154) | Istanbul University | 2017-01-01 |
| Study to Compare the Efficacy of Mycophenolate Mofetil in Systemic Sclerosis Related Early Interstitial Lung Disease (NCT02896205) | Post Graduate Institute of Medical Education and Research, Chandigarh | 2016-10-01 |
| Bosentan Treatment of Digital Ulcers Related to Systemic Sclerosis (NCT02798055) | Elpen Pharmaceutical Co. Inc. | 2016-09-30 |
| Riociguat in Scleroderma Associated Digital Ulcers (NCT02915835) | Dinesh Khanna, MD, MS | 2016-09-01 |
| Effectiveness of a Home-based, Self-administered Exercise Program for Hands in Patients With Systemic Sclerosis (NCT04481984) | Cukurova University | 2016-07-15 |
| Novel Rehabilitation Strategies to Improve Arm Function in Patients With Scleroderma (NCT02837549) | University of Michigan | 2016-07-01 |
| Ozone Therapy in the Treatment of Digital Ulcers in Patients With Systemic Sclerosis (NCT02733978) | Assiut University | 2016-06-01 |
| Duke Scleroderma Clinic Patient Registry (NCT02851875) | Duke University | 2016-04-01 |
| Taking Charge of Systemic Sclerosis (NCT02494401) | University of Michigan | 2016-03-06 |
| Comparative Effectiveness Trial in the Treatment of Pediatric Plaque Morphea (NCT02680717) | Medical College of Wisconsin | 2016-03-01 |
| Comparing and Combining Bortezomib and Mycophenolate in SSc Pulmonary Fibrosis (NCT02370693) | Northwestern University | 2016-03-01 |
| A Double-Blinded Study to Evaluate the Safety, Tolerability, and Efficacy of BMS-986020 Versus Placebo in Diffuse Cutaneous Systemic Sclerosis (dcSSc) (NCT02588625) | Bristol-Myers Squibb | 2016-02-01 |
| Safety & Suitability of Dabigatran to Inhibit Thrombin in Scleroderma (NCT02426229) | Medical University of South Carolina | 2016-02-01 |
| The Effect of Ethanol Extract Physalis Angulata Linn. in Scleroderma Patients With Standard Therapy (NCT03141125) | Indonesia University | 2016-01-01 |
| Pregnancy and Medically Assisted Conception in Rare Diseases (NCT02450396) | Assistance Publique - Hôpitaux de Paris | 2015-06-01 |
| Scleroderma Treatment With Celution Processed Adipose Derived Regenerative Cells (STAR) (NCT02396238) | Cytori Therapeutics | 2015-05-15 |
| Scleroderma Treatment With Celution Processed ADRCs Registry (NCT02328625) | Cytori Therapeutics | 2015-04-01 |
| Hands on - a Hand Care Guide in Systemic Sclerosis (NCT02610842) | University of Campinas, Brazil | 2015-01-01 |
| Efficacy of Botulinum Toxin In Scleroderma-Associated Raynaud's Syndrome (NCT02165111) | Johns Hopkins University | 2015-01-01 |
| Endothelial Microparticles in Systemic Sclerosis Pulmonary Hypertension (NCT02331225) | Louisiana State University Health Sciences Center in New Orleans | 2014-12-01 |
| Effects of Probiotics on Gastrointestinal Symptoms and on the Immune System in Patients With Systemic Sclerosis (NCT02302352) | Federal University of São Paulo | 2014-12-01 |
| Rituximab Versus Cyclophosphamide in Connective Tissue Disease-ILD (NCT01862926) | Royal Brompton & Harefield NHS Foundation Trust | 2014-11-01 |
| Zibotentan Better Renal Scleroderma Outcome Study (NCT02047708) | University College, London | 2014-10-01 |
| The Scleroderma Biorepository and Pathogenesis Study (STOP Scleroderma) (NCT02887495) | George Washington University | 2014-07-01 |
| Divalproex Sodium in the Treatment of the Cutaneous Manifestations of Scleroderma (NCT02166229) | Yale University | 2014-06-01 |
| Scleroderma ARFI Imaging of the Skin (NCT02006420) | University of Michigan | 2013-12-01 |
| Novel Screening Strategies for Scleroderma PAH (NCT01959815) | University of Michigan | 2013-09-26 |
| At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions (NCT01931644) | Sanguine Biosciences | 2013-07-01 |
| Gastroesophageal Reflux Treatment in Scleroderma (NCT01878526) | Khon Kaen University | 2013-06-01 |
| Cyclophosphamide Systemic Sclerosis Associated Interstitial Lung Disease (NCT01570764) | Assistance Publique - Hôpitaux de Paris | 2013-01-14 |
| Calcinosis in a Single-Center Scleroderma Population (NCT02062125) | Rutgers, The State University of New Jersey | 2012-10-31 |
| Autologous Stem Cell Transplantation for Progressive Systemic Sclerosis (NCT01895244) | University Hospital Tuebingen | 2012-09-01 |
| Regulatory B Cells in Inflammatory Rheumatisms and Biomarkers of Response to Biologic Treatments (NCT01642706) | University Hospital, Montpellier | 2012-07-02 |
| Morbidity and Mortality Follow Up for the Scleroderma Lung Study (NCT01762449) | Duke University | 2012-07-01 |
| Empirical Comparative Study of Variation Blood Level Antibody Vitamin D at Scleroderma (SSc) Patients Compared Healthy Peoples (NCT01553890) | Meir Medical Center | 2012-03-01 |
| Probiotics in Patients With Moderate-to-severe Distention/ Bloating From Systemic Sclerosis (NCT01497743) | University of Michigan | 2012-02-01 |
| IL1-TRAP, Rilonacept, in Systemic Sclerosis (NCT01538719) | Boston University | 2011-12-01 |
| Campath-1h Phase I/II Pilot Trial as Immunoablative Therapy for Refractory Systemic Sclerosis (NCT01639573) | Children's Hospital Los Angeles | 2011-04-01 |
| Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford (NCT01793168) | Sanford Health | 2010-07-01 |
| Finger Hardness Measure in Scleroderma (NCT01111786) | Mayo Clinic | 2010-04-01 |
| A Study of the Safety and Tolerability of MEDI-551 in Scleroderma (NCT00946699) | MedImmune LLC | 2010-03-01 |
| A Randomized Control Trial to Assess the Efficacy of Tadalafil in Raynaud's Phenomenon in Scleroderma (NCT01117298) | Sanjay Gandhi Postgraduate Institute of Medical Sciences | 2009-11-01 |
| A Study to Evaluate Safety and Tolerability of Multiple Doses of MEDI-546 in Adult Subjects With Scleroderma (NCT00930683) | MedImmune LLC | 2009-09-01 |
| Digital Ischemic Lesions in Scleroderma Treated With Oral Treprostinil Diethanolamine (NCT00775463) | United Therapeutics | 2009-05-01 |
| Safety Evaluation of Dasatinib in Subjects With Scleroderma Pulmonary Fibrosis (NCT00764309) | Bristol-Myers Squibb | 2009-01-01 |
| Proof of Concept Trial of Gleevec (Imatinib) in Active Diffuse Scleroderma (NCT01545427) | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2008-04-01 |
| Duke Autoimmunity in Pregnancy Registry (NCT00513591) | Duke University | 2007-08-01 |
| A Rho-kinase Inhibitor (Fasudil) in the Treatment of Raynaud's Phenomenon (NCT00498615) | Johns Hopkins University | 2007-04-01 |