| The Effect of Compression Stockings on the Complaints of Pregnant Women With Restless Leg Syndrome (NCT05795868) | TC Erciyes University | 2022-04-25 |
| Noninvasive Peripheral Nerve Stimulation for Medication-Naive and Medication-Refractory RLS (NCT05214963) | Noctrix Health, Inc. | 2022-03-08 |
| Mainz Register of Patients With Sleep Disorders (NCT05321355) | Johannes Gutenberg University Mainz | 2022-02-01 |
| Treatment of Restless Legs Symptoms With Pramipexole to Improve the Outcomes of Protracted Opioid Withdrawal in OUD (NCT04759703) | Massachusetts General Hospital | 2022-01-24 |
| Exercise Training Versus Ropinirole in Treating Restless Legs Syndrome Among Hemodialysis Patients (NCT06468371) | Lahore General Hospital | 2022-01-02 |
| Extension Study Evaluating NTX100 Neuromodulation System for Medication-Refractory Primary RLS (NCT05196828) | Noctrix Health, Inc. | 2021-12-20 |
| Clinical Features Associated With Restless Legs Syndrome. (NCT05044520) | University Hospital, Montpellier | 2021-09-01 |
| The Effect of Progressive Muscle Relaxation Exercise Training Given to Pregnant Women With Restless Leg Syndrome (NCT04853771) | Gazi University | 2021-04-06 |
| Noninvasive Peripheral Nerve Stimulation for Restless Legs Syndrome During Opioid Medication Reduction (NCT04698343) | Noctrix Health, Inc. | 2021-04-06 |
| Hypnosis and Direct Autonomic Experience Influence on Chronic Symptoms (NCT04303143) | Inner Group Inc. | 2021-03-01 |
| Anesthetic Management of Patients With Chronic Sleep Disorders (NCT04827329) | University Hospital, Montpellier | 2021-03-01 |
| Investigation of the Effects of Different Exercise Programs in Patients With Restless Legs Syndrome. (NCT04711993) | Gulhane School of Medicine | 2021-02-17 |
| Oral Iron Frequency for Childhood Restless Leg Syndrome/Periodic Limb Movement Disorder (NCT04610827) | Mayo Clinic | 2020-11-16 |
| Autonomic Assessment in Patients With Restless Legs Syndrome (NCT04906486) | Kocaeli Derince Education and Research Hospital | 2020-11-12 |
| The Effect of Hot and Cold Water Application on Pregnant Women With Restless Leg Syndrome (NCT04786314) | TC Erciyes University | 2020-09-30 |
| The Effect of Magnesium Citrate Supplementation in Restless Legs Syndrome (RLS) (NCT04462796) | OSF Healthcare System | 2020-07-10 |
| Alpha-lipoic Acid Combined With B Vitamins Shows Promise for Treating Restless Legs Syndrome (NCT06324760) | Uriach Consumer Healthcare | 2020-03-04 |
| Investigation of the Effects of Medium Cut-off Dialyzers Versus High-Flux Dialyzers on Clinical and Laboratory Parameters of Prevalent Hemodialysis Patients (NCT05698420) | Sanliurfa Mehmet Akif Inan Education and Research Hospital | 2020-03-01 |
| RCT for Pregabalin in Restless Legs Syndrome in South Korea (NCT04161027) | Seoul National University Hospital | 2020-02-24 |
| Aerobic And Strength Training Exercises For Restless Leg Syndrome In Patients With Diabetes (NCT04316052) | Riphah International University | 2020-02-15 |
| Efficacy of BIPAMS for Restless Legs Syndrome in Adults With Multiple Sclerosis: A Pilot Study (NCT04061681) | University of Alabama at Birmingham | 2020-01-01 |
| Advancing Understanding of Transportation Options (NCT04141891) | University of Colorado, Denver | 2019-12-12 |
| A Follow-up Study of Rotigotine Patch in Adolescent Subjects With Restless Legs Syndrome (NCT03992196) | UCB Biopharma SRL | 2019-12-03 |
| Impact of Acute Leg Cycling at Various Intensities on RLS Severity in Persons With MS (NCT03849001) | University of Alabama at Birmingham | 2019-09-01 |
| Effects of Transcutaneous Vagus Nerve Stimulation in Chronic Pain Patients and Healthy Controls (NCT05007743) | University Medical Center Goettingen | 2019-07-21 |
| Noninvasive Peripheral Nerve Stimulation for Restless Legs Syndrome (NCT04700683) | Noctrix Health, Inc. | 2019-07-14 |
| Pramipexole for Restless Leg Syndrome in Peritoneal Dialysis Patients (NCT03817554) | Dong Jie | 2019-07-01 |
| DIalysis Symptom COntrol-Restless Legs Syndrome Trial (NCT03806530) | Population Health Research Institute | 2019-05-01 |
| REST Study (CompRESsion Therapy for RLS) (NCT03852771) | Radial Medical, Inc. | 2019-03-12 |
| Effectiveness of Ropinirole and Gabapentin for the Treatment of RLS in Patients on Maintenance HD (NCT03708237) | University of Alberta | 2019-02-19 |
| Treatment of Restless Legs Syndrome With the Hypocretin Antagonist Suvorexant (NCT03755310) | Diego García-Borreguero, MD, PhD | 2019-02-01 |
| A Study of Rotigotine Patch in Adolescent Subjects With Restless Legs Syndrome of Unknown Cause (NCT03728933) | UCB Biopharma SRL | 2018-12-20 |
| The Effect of Hot Water Application in Pregnant Women With Restless Legs Syndrome: A Randomised Controlled Study (NCT04887103) | TC Erciyes University | 2018-10-16 |
| Clinical Trial Assessing the Efficacy and Safety of BP1.4979 in Restless Legs Syndrome (NCT03345953) | Bioprojet | 2018-02-06 |
| Treatment of Restless Leg Syndrome (RLS) Augmentation With Ecopipam, a D1 Specific Antagonist (NCT03218969) | William Ondo, MD | 2017-09-18 |
| Analysis of Sympathetic Activity in Willis-Ekbom Disease (NCT02929732) | University Hospital, Montpellier | 2017-03-21 |
| Treatment of RLS/WED Symptoms Through Sensory Counter-stimulation (NCT03249779) | Mayo Clinic | 2016-12-01 |
| Cardiovascular Variability, Heart Rate Response, and Electromyogram Power Associated With Periodic Leg Movements. (NCT03076541) | Centre Hospitalier Universitaire de Saint Etienne | 2016-09-01 |
| Effects of Progressive Muscle Relaxation Exercises During Pregnancy (NCT05851001) | Ege University | 2016-04-01 |
| A Study on the Use of the MMF07 Foot Massager and Heat Therapy Treatments for Restless Leg Syndrome (NCT02526277) | Ariane Park | 2016-01-06 |
| Vitamin D in the Treatment of Primary Restless Legs Syndrome (NCT02256215) | King Abdulaziz University | 2015-12-01 |
| Infra-slow Oscillations During Sleep (NCT02532608) | Stephany Fulda | 2015-10-01 |
| Sleep Deficiency and Stroke Outcome (NCT02559739) | Insel Gruppe AG, University Hospital Bern | 2015-07-01 |
| Effects of Gabapentin Enacarbil on Arousals, Heart Rate, Blood Pressure and PLMs in Restless Legs Syndrome (NCT02424695) | Cleveland Sleep Research Center | 2015-06-01 |
| IV Iron Treatment of Restless Legs Syndrome (NCT02484768) | Pharmacosmos A/S | 2015-01-01 |
| Apelin in Willis Ekbom Disease (NCT02264600) | Acibadem University | 2014-11-01 |
| Switching From Oral Dopamine Agonists to Rotigotine (NCT01976871) | John Winkelman, MD, PhD | 2014-08-01 |
| Pilot Study: Randomized, Placebo-controlled Comparator Trial of IV vs Oral Iron Treatment of RLS With IDA. (IVOR-IDA) (NCT02499354) | Auerbach Hematology Oncology Associates P C | 2014-08-01 |
| Butrans for Treatment of Restless Legs Syndrome (NCT02138357) | Massachusetts General Hospital | 2014-04-01 |
| Clinical Observational Study: IBD Patients With Restless-legs-syndrome and Iron Deficiency Syndrome (NCT03457571) | Charite University, Berlin, Germany | 2014-02-01 |
| Cranial Electrotherapy for Military Beneficiaries With Restless Legs Syndrome (NCT02419014) | Tripler Army Medical Center | 2014-02-01 |
| Targeting Dopamine Therapy in RLS (NCT01937169) | Tel-Aviv Sourasky Medical Center | 2014-01-01 |
| Autonomic Function and Cardiovascular Risk in Restless Legs Syndrome (NCT02025608) | Mauro Manconi | 2013-12-01 |
| Vasculaire Leg Compression Device for the Treatment of Restless Legs Syndrome - A Prospective Clinical Study (NCT01861652) | Walter Reed National Military Medical Center | 2013-07-01 |
| Specified Drug Use-Results Survey of Regnite (NCT01887613) | Astellas Pharma Inc | 2012-10-01 |
| Glutamate, Hyperarousal and Restless Legs Syndrome (NCT01675323) | Johns Hopkins University | 2012-08-01 |
| Gabapentin Enacarbil (GSK1838262) Adult Restless Leg Syndrome (RLS) Post Marketing Commitment Study (NCT01668667) | XenoPort, Inc. | 2012-06-01 |
| Validation Study for an Unobtrusive Online Sleep Measurement System (NCT01633151) | Beddit.com Ltd | 2012-06-01 |
| A Sleep Laboratory Study to Investigate the Safety and Efficacy of the Rotigotine Skin Patch in Subjects With Restless Legs Syndrome and End-Stage Renal Disease Requiring Hemodialysis (NCT01537042) | UCB BIOSCIENCES GmbH | 2012-04-01 |
| Rotigotine Effect on All-day Functioning and Quality of Life in Subjects With Moderate to Severe Restless Legs Syndrome (RLS) (NCT01569464) | UCB Pharma | 2012-03-01 |
| A Study to Evaluate the Effect of Gabapentin on Cardiac Repolarization in Healthy Volunteers (NCT01516372) | XenoPort, Inc. | 2012-01-01 |
| Long-Term Follow-Up Study for Safety, Efficacy and Tolerability of Rotigotine in Adolescents With Restless Legs Syndrome (NCT01498120) | UCB BIOSCIENCES, Inc. | 2011-12-01 |
| Dose Escalating Study of Rotigotine in Pediatric Subjects With Restless Legs Syndrome (NCT01495793) | UCB BIOSCIENCES, Inc. | 2011-12-01 |
| Effects of Neupro on Cardiovascular Observations in Patients With Restless Legs Syndrome (NCT01455012) | UCB BIOSCIENCES GmbH | 2011-09-01 |
| Drug Drug Interaction Study With Gabapentin Enacarbil and Morphine (NCT01476124) | XenoPort, Inc. | 2011-08-01 |
| Effect on RLS Symptom Severity After Switching to Neupro® in Patients Who Previously Experienced Augmentation (NCT01386944) | UCB Pharma | 2011-07-01 |
| Safety and Efficacy of Rasagiline in Restless Legs Syndrome (NCT01192503) | University of Virginia | 2010-09-01 |
| Survey on Long-Term Use of BI-Sifrol® Tablets in Patients With Restless Legs Syndrome (NCT01174459) | Boehringer Ingelheim | 2010-08-01 |
| 12-Week Efficacy And Safety Of Pregabalin In Treating Restless Legs Syndrome (RLS) Subjects (NCT01061372) | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 2010-05-01 |
| Altered Brain GABA and Glutamate in Restless Legs Syndrome (NCT01109537) | Brigham and Women's Hospital | 2010-04-01 |
| Gabapentin and Risk of Pancreatic Cancer and Renal Cancer (GPRD) (NCT01138124) | GlaxoSmithKline | 2010-03-01 |
| Polysomnography Study Of Pregabalin And Pramipexole Versus Placebo In Patients With Restless Legs Syndrome And Associated Sleep Disturbance (NCT00991276) | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 2009-12-01 |
| Clinical Evaluation of Ropinirole IR (Immediate Release) Tablets in Patients Who Are Diagnosed With Symptomatic Restless Legs Syndrome (RLS) Associated With Chronic Kidney Disease (CKD) Managed With Haemodialysis (Including Haemofiltration and Haemodiafiltration) (NCT00996944) | GlaxoSmithKline | 2009-11-30 |
| Restless Legs Syndrome Treatment With Botulinum Toxin (NCT00949806) | University Hospital, Bordeaux | 2009-08-01 |
| Non-interventional Observational Study on the Influence of Pramipexole on Sensory Symptoms of Restless Legs Syndrome (RLS) (NCT00887289) | Boehringer Ingelheim | 2009-04-01 |
| Suggested Immobilization Test (SIT) Test for Early Detection of Restless Legs Syndrome (RLS) Augmentation - Proof of Concept (NCT00867893) | Johns Hopkins University | 2009-02-01 |
| Efficacy and Safety Study of Aplindore in Patients With Restless Legs Syndrome (NCT00834327) | Neurogen Corporation | 2009-02-01 |
| Polysomnography Study of GSK1838262 Extended Release Tablets Versus Placebo in RLS and Associated Sleep Disturbance (NCT00748098) | XenoPort, Inc. | 2008-10-01 |
| Neuroma Injections to Treat Restless Legs Syndrome - RCT (NCT00656110) | Lowcountry Infectious Diseases | 2008-04-01 |
| Pramipexole in Out-patients With Idiopathic Restless Legs Syndrome (IRLS) (NCT00654498) | Boehringer Ingelheim | 2008-04-01 |
| Lyrica Dose Response Study With Restless Legs Syndrome (RLS) Patients (NCT00676403) | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 2008-04-01 |
| Study of Vitamin C, Vitamin E and Their Combination to Treat Restless Legs Syndrome in Hemodialysis Patients (NCT01125033) | Shiraz University of Medical Sciences | 2008-03-01 |
| Bupropion and Restless Legs Syndrome (NCT00621517) | East Tennessee State University | 2008-02-01 |
| The Effects of Aplindore on the Treatment of Signs and Symptoms of Restless Legs Syndrome (NCT00626418) | Ligand Pharmaceuticals | 2008-02-01 |
| Restless Legs Syndrome in Stroke Patients (NCT01967303) | Rambam Health Care Campus | 2008-01-01 |
| Long-term Efficacy and Safety of Gabapentin Enacarbil in Japanese Restless Legs Syndrome Patients (NCT02658188) | Astellas Pharma Inc | 2007-12-01 |
| Safety and Effect of Mirapex(Pramipexole) Tablet Among Korean RLS (NCT01170091) | Boehringer Ingelheim | 2007-12-01 |
| Pregabalin (Lyrica) for the Treatment of Restless Legs Syndrome (NCT00584246) | University of South Florida | 2007-11-01 |
| Cross-Sectional Study: Prevalence of Restless Legs Syndrome in Patients With Unpleasant Sensations of the Legs (NCT00557258) | Boehringer Ingelheim | 2007-11-01 |
| ASP8825 - Study in Patients With Restless Legs Syndrome (NCT00530530) | Astellas Pharma Inc | 2007-09-01 |
| Sifrol (Pramipexole) Onset of Action and Impact: a 12-weeks Observational Study in Patients With Primary Restless Legs Syndrome (NCT00721279) | Boehringer Ingelheim | 2007-09-01 |
| Clinical Evaluation of Ropinirole CR-RLS ( SK&F101468)Tablets in Restless Legs Syndrome (NCT00530790) | GlaxoSmithKline | 2007-08-23 |
| Long-term Efficacy, Safety and Tolerability of Pramipexole in Patients With Idiopathic Moderate to Severe Restless Legs Syndrome (RLS) (NCT00472199) | Boehringer Ingelheim | 2007-05-01 |
| Botulinum Toxin to Treat Restless Legs Syndrome (NCT00479154) | National Institute of Neurological Disorders and Stroke (NINDS) | 2007-05-01 |
| Simulated Driving Study in Restless Legs Syndrome (NCT01332318) | XenoPort, Inc. | 2007-04-01 |
| Non-interventional Observational Study of Pramipexole in Restless Legs Syndrome: Impact on Quality of Life (NCT00539461) | Boehringer Ingelheim | 2007-02-01 |
| Dose-Response and Pharmacokinetics of Gabapentin Enacarbil (GEn [XP13512 / GSK1838262]) in Restless Legs Syndrome (NCT01332305) | XenoPort, Inc. | 2007-01-01 |
| Biotin Deficiency and Restless Legs Syndrome (NCT02011191) | Heidi Moretti, MS, RD | 2006-12-01 |
| 12-week Polysomnography Study of Ropinirole Controlled Release for Restless Legs Syndrome (NCT00373542) | GlaxoSmithKline | 2006-10-01 |
| Exercise Training in Dialysis Patients With Restless Legs Syndrome (RLS) (NCT00942253) | University of Thessaly | 2006-09-01 |