Atlas Trials

Refractory Chronic Lymphocytic Leukemia

158 clinical trials · Condition

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RecordFirmDate
Ipilimumab, Ibrutinib, and Nivolumab for the Treatment of Chronic Lymphocytic Leukemia and Richter Transformation (NCT04781855)M.D. Anderson Cancer Center2022-07-14
Genetically Engineered Cells (Anti-CD19/CD20/CD22 CAR T-cells) for the Treatment of Relapsed or Refractory Lymphoid Malignancies (NCT05418088)Sumithira Vasu2022-06-30
Venetoclax Resistance Landscape in Chronic Lymphocytic Leukemia (NCT05246345)University Hospital, Clermont-Ferrand2022-03-07
A Study to Evaluate VIP152 in Subjects With Relapsed/Refractory Chronic Lymphocytic Leukemia or Richter Syndrome (NCT04978779)Vincerx Pharma, Inc.2021-12-16
Donor Stem Cell Transplant With Treosulfan, Fludarabine, and Total-Body Irradiation for the Treatment of Hematological Malignancies (NCT04195633)Fred Hutchinson Cancer Center2021-01-25
Daratumumab and Ibrutinib for the Treatment of Relapsed or Refractory Chronic Lymphocytic Leukemia, DIRECT Study (NCT04230304)Mayo Clinic2020-11-11
CC-486, Lenalidomide, and Obinutuzumab for the Treatment of Recurrent or Refractory CD20 Positive B-cell Lymphoma (NCT04578600)Joseph Tuscano2020-10-23
Rituximab, Idelalisib, and Venetoclax in Relapsed/Refractory CLL/SLL (NCT03639324)Virginia Commonwealth University2020-10-02
Acalabrutinib and Venetoclax With or Without Early Obinutuzumab for the Treatment of High Risk, Recurrent, or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (NCT04169737)M.D. Anderson Cancer Center2020-07-29
CD19-Specific T Cells Post AlloSCT (NCT03579888)M.D. Anderson Cancer Center2020-06-26
Nivolumab for Relapsed, Refractory, or Detectable Disease Post Chimeric Antigen Receptor T-cell Treatment in Patients With Hematologic Malignancies (NCT04205409)University of Washington2020-06-05
Intermittent Duvelisib Dosing in Treating Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (NCT03961672)City of Hope Medical Center2020-05-13
Study of a Triple Combination Therapy, DTRM-555, in Patients With R/R CLL or R/R Non-Hodgkin's Lymphomas (NCT04305444)Zhejiang DTRM Biopharma2020-04-24
Serial Measurements of Molecular and Architectural Responses to Therapy (SMMART) PRIME Trial (NCT03878524)OHSU Knight Cancer Institute2020-04-01
Trabectedin and Venetoclax in Treating Patients With Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Resistant or Intolerant to a BTK Inhibitor (NCT03884972)M.D. Anderson Cancer Center2019-06-18
Modified Immune Cells (CD19-CD22 CAR T Cells) in Treating Patients With Recurrent or Refractory CD19 Positive, CD22 Positive Leukemia or Lymphoma (NCT04029038)M.D. Anderson Cancer Center2019-05-15
Pevonedistat and Ibrutinib in Treating Participants With Relapsed or Refractory CLL or Non-Hodgkin Lymphoma (NCT03479268)City of Hope Medical Center2018-04-27
A Phase I/II Study to Evaluate the Safety of Cellular Immunotherapy Using Autologous T Cells Engineered to Express a CD20-Specific Chimeric Antigen Receptor for Patients With Relapsed or Refractory B Cell Non-Hodgkin Lymphomas (NCT03277729)Fred Hutchinson Cancer Center2017-12-05
Venetoclax and Ibrutinib in Patients With Relapsed/Refractory CLL or SLL (NCT03045328)Steven E. Coutre2017-09-26
Metformin Hydrochloride and Ritonavir in Treating Patients With Relapsed or Refractory Multiple Myeloma or Chronic Lymphocytic Leukemia (NCT02948283)City of Hope Medical Center2017-09-05
Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by Tandem CAR T Cells Targeting CD19 and CD22 (NCT03185494)Chinese PLA General Hospital2017-08-01
Entospletinib and Obinutuzumab in Treating Patients With Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Non-Hodgkin Lymphoma (NCT03010358)Alexey Danilov, MD2017-07-17
Treatment of Relapsed and/or Chemotherapy Refractory B-cell Malignancy by Tandem CAR T Cells Targeting CD19 and CD20 (NCT03097770)Chinese PLA General Hospital2017-04-01
Ibrutinib in Treating Patients With Refractory or Relapsed Lymphoma After Donor Stem Cell Transplant (NCT02869633)Vanderbilt-Ingram Cancer Center2016-11-01
Anti-CD19 CAR T Infusion Combined With Allogeneic Stem Cell Transplantation for B-cell Leukemia/Lymphoma (NCT03110640)First Affiliated Hospital of Wenzhou Medical University2016-10-01
Venetoclax and Ibrutinib in Treating Patients With Chronic or Small Lymphocytic Leukemia (NCT02756897)M.D. Anderson Cancer Center2016-07-07
Lenalidomide and Obinutuzumab in Treating Patients With Recurrent or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (NCT02225275)M.D. Anderson Cancer Center2016-03-31
Competitive Transfer of αCD19-TCRz-CD28 and αCD19-TCRz-CD137 CAR-T Cells for B-cell Leukemia/Lymphoma (NCT02685670)The Second Affiliated Hospital of Henan University of Traditional Chinese Medicine2016-02-01
Buparlisib and Ofatumumab or Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia (NCT02614508)Emory University2016-01-01
Bcl-2 Inhibitor GDC-0199 in Combination With Obinutuzumab and Ibrutinib in Treating Patients With Relapsed, Refractory, or Previously Untreated Chronic Lymphocytic Leukemia (NCT02427451)Kerry Rogers2015-08-03
Nivolumab and Ibrutinib in Treating Patients With Relapsed, Refractory, or High-Risk Untreated Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or Richter Transformation (NCT02420912)M.D. Anderson Cancer Center2015-06-19
Selinexor and Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Aggressive Non-Hodgkin Lymphoma (NCT02303392)Jennifer Woyach2015-06-09
Pembrolizumab Alone or With Idelalisib or Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Other Low-Grade B-Cell Non-Hodgkin Lymphomas (NCT02332980)Mayo Clinic2015-02-19
CPI-613, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma (NCT02168907)Wake Forest University Health Sciences2014-12-01
Everolimus and Bendamustine Hydrochloride in Treating Patients With Relapsed or Refractory Hematologic Cancer (NCT02240719)University of California, Davis2014-10-01
Ibrutinib in Treating Relapsed or Refractory B-Cell Non-Hodgkin Lymphoma in Patients With HIV Infection (NCT02109224)National Cancer Institute (NCI)2014-09-01
Lenalidomide, Ibrutinib, and Rituximab in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma That Is Metastatic or Cannot Be Removed by Surgery (NCT02160015)National Cancer Institute (NCI)2014-05-20
Phase II MOR00208 in Combination With Lenalidomide for Patients With Relapsed or Refractory CLL, SLL or PLL or Older Patients With Untreated CLL, SLL or PLL (NCT02005289)Ohio State University Comprehensive Cancer Center2014-01-17
Single or Double Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Hematologic Malignancies (NCT01652014)University of Medicine and Dentistry of New Jersey2014-01-01
Vorinostat, Tacrolimus, and Methotrexate in Preventing GVHD After Stem Cell Transplant in Patients With Hematological Malignancies (NCT01789255)National Cancer Institute (NCI)2013-06-01
Laboratory Treated T Cells in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Non-Hodgkin Lymphoma, or Acute Lymphoblastic Leukemia (NCT01865617)Fred Hutchinson Cancer Center2013-05-22
NK Cells in Cord Blood Transplantation (NCT01619761)M.D. Anderson Cancer Center2013-05-03
Lenalidomide and Ibrutinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (NCT01886859)National Cancer Institute (NCI)2013-04-26
Genetically Engineered Lymphocyte Therapy in Treating Patients With Lymphoma That is Resistant or Refractory to Chemotherapy (NCT01735604)Chinese PLA General Hospital2013-01-01
Vaccine Therapy in Preventing Cytomegalovirus Infection in Patients With Hematological Malignancies Undergoing Donor Stem Cell Transplant (NCT01588015)City of Hope Medical Center2012-10-29
Romidepsin in Treating Patients With Lymphoma, Chronic Lymphocytic Leukemia, or Solid Tumors With Liver Dysfunction (NCT01638533)National Cancer Institute (NCI)2012-08-03
Mechanical Stimulation in Preventing Bone Density Loss in Patients Undergoing Donor Stem Cell Transplant (NCT01558778)Roswell Park Cancer Institute2012-05-01
Alisertib in Combination With Vorinostat in Treating Patients With Relapsed or Recurrent Hodgkin Lymphoma, B-Cell Non-Hodgkin Lymphoma, or Peripheral T-Cell Lymphoma (NCT01567709)National Cancer Institute (NCI)2012-04-16
CD19 CAR T Cells for B Cell Malignancies After Allogeneic Transplant (NCT01475058)Fred Hutchinson Cancer Center2012-04-01
Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies (NCT01529827)Roswell Park Cancer Institute2012-02-28
Ofatumumab and Dinaciclib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or B-Cell Prolymphocytic Leukemia (NCT01515176)National Cancer Institute (NCI)2012-01-01
Dasatinib in Treating Patients With Chronic Lymphocytic Leukemia (NCT01441882)OHSU Knight Cancer Institute2011-10-01
Akt Inhibitor MK2206, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (NCT01369849)National Cancer Institute (NCI)2011-09-01
Veliparib, Bendamustine Hydrochloride, and Rituximab in Treating Patients With Relapsed or Refractory Lymphoma, Multiple Myeloma, or Solid Tumors (NCT01326702)National Cancer Institute (NCI)2011-07-01
Methoxyamine and Fludarabine Phosphate in Treating Patients With Relapsed or Refractory Hematologic Malignancies (NCT01658319)Case Comprehensive Cancer Center2011-05-01
MK2206 in Treating Younger Patients With Recurrent or Refractory Solid Tumors or Leukemia (NCT01231919)National Cancer Institute (NCI)2011-01-01
Imprime PGG, Alemtuzumab, and Rituximab in Treating Patients With High Risk Chronic Lymphocytic Leukemia (NCT01269385)Mayo Clinic2011-01-01
Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant (NCT01199562)City of Hope Medical Center2010-12-01
Sirolimus, Cyclosporine, and Mycophenolate Mofetil in Preventing Graft-versus-Host Disease in Treating Patients With Blood Cancer Undergoing Donor Peripheral Blood Stem Cell Transplant (NCT01251575)Fred Hutchinson Cancer Center2010-12-01
Azadirachta Indica in Treating Patients With Chronic Lymphocytic Leukemia (NCT01251250)Roswell Park Cancer Institute2010-12-01
Lenalidomide After Donor Bone Marrow Transplant in Treating Patients With High-Risk Hematologic Cancers (NCT01254578)National Cancer Institute (NCI)2010-11-24
Graft-Versus-Host Disease Prophylaxis in Treating Patients With Hematologic Malignancies Undergoing Unrelated Donor Peripheral Blood Stem Cell Transplant (NCT01231412)Fred Hutchinson Cancer Center2010-11-01
Study of Carfilzomib in Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL) or Prolymphocytic Leukemia (PLL) (NCT01212380)Ohio State University Comprehensive Cancer Center2010-10-01
Palifermin in Preventing Chronic Graft-Versus-Host Disease in Patients Who Have Undergone Donor Stem Cell Transplant for Hematologic Cancer (NCT01233921)Martin, Paul2010-09-01
Deferasirox for Treating Patients Who Have Undergone Allogeneic Stem Cell Transplant and Have Iron Overload (NCT01159067)City of Hope Medical Center2010-07-01
Plerixafor and Filgrastim For Mobilization of Donor Peripheral Blood Stem Cells Before A Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies (NCT01076270)Fred Hutchinson Cancer Center2010-06-01
Alvespimycin Hydrochloride in Treating Patients With Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, or B-Cell Prolymphocytic Leukemia (NCT01126502)National Cancer Institute (NCI)2010-05-01
Massage Therapy Given by Caregiver in Treating Quality of Life of Young Patients Undergoing Treatment for Cancer (NCT01053494)Wake Forest University Health Sciences2010-04-01
Cyclophosphamide, Alvocidib, and Rituximab in Treating Patients With High Risk B-Cell Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (NCT01076556)National Cancer Institute (NCI)2010-04-01
Autologous Peripheral Blood Stem Cell Transplant Followed by Donor Bone Marrow Transplant in Treating Patients With High-Risk Hodgkin Lymphoma, Non-Hodgkin Lymphoma, Multiple Myeloma, or Chronic Lymphocytic Leukemia (NCT01008462)Fred Hutchinson Cancer Center2010-03-18
CART19 to Treat B-Cell Leukemia or Lymphoma That Are Resistant or Refractory to Chemotherapy (NCT01029366)University of Pennsylvania2010-03-17
Rituximab in Preventing Acute Graft-Versus-Host Disease in a Donor Stem Cell Transplant for Hematologic Cancer (NCT01044745)University of Nebraska2009-12-10
Sunitinib Malate in Treating HIV-Positive Patients With Cancer Receiving Antiretroviral Therapy (NCT00890747)National Cancer Institute (NCI)2009-08-01
Panobinostat and Everolimus in Treating Patients With Recurrent Multiple Myeloma, Non-Hodgkin Lymphoma, or Hodgkin Lymphoma (NCT00918333)Mayo Clinic2009-06-01
Obatoclax Mesylate, Vincristine Sulfate, Doxorubicin Hydrochloride, and Dexrazoxane Hydrochloride in Treating Young Patients With Relapsed or Refractory Solid Tumors, Lymphoma, or Leukemia (NCT00933985)National Cancer Institute (NCI)2009-06-01
Rituximab in Treating Patients Undergoing Donor Peripheral Blood Stem Cell Transplant for Relapsed or Refractory B-cell Lymphoma (NCT00867529)Fred Hutchinson Cancer Center2009-02-01
Fludarabine Phosphate, Melphalan, Total-Body Irradiation, Donor Stem Cell Transplant in Treating Patients With Hematologic Cancer or Bone Marrow Failure Disorders (NCT00856388)Roswell Park Cancer Institute2009-01-14
Fludarabine Phosphate, Rituximab, and Bevacizumab in Treating Patients With B-Cell Chronic Lymphocytic Leukemia That Has Relapsed or Not Responded To Treatment (NCT00845104)Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium2009-01-01
Bendamustine Plus Alemtuzumab for Refractory Chronic Lymphocytic Leukemia (CLL) (NCT00947388)Case Comprehensive Cancer Center2008-11-01
Fludarabine Phosphate, Cyclophosphamide, Total-Body Irradiation, and Donor Bone Marrow Transplant Followed by Donor Natural Killer Cell Therapy, Mycophenolate Mofetil, and Tacrolimus in Treating Patients With Hematologic Cancer (NCT00789776)Fred Hutchinson Cancer Center2008-10-13
Dasatinib in Treating Patients With Solid Tumors or Lymphomas That Are Metastatic or Cannot Be Removed By Surgery (NCT00608361)National Cancer Institute (NCI)2008-10-01
Ondansetron in Preventing Nausea and Vomiting in Patients Undergoing Stem Cell Transplant (NCT00795769)Fred Hutchinson Cancer Center2008-08-08
Rituximab, Cyclophosphamide, Bortezomib, and Dexamethasone in Treating Patients With Relapsed or Refractory Low-Grade Follicular Lymphoma, Waldenstrom Macroglobulinemia, or Mantle Cell Lymphoma (NCT00711828)Mayo Clinic2008-08-01
Internet-Based Program With or Without Telephone-Based Problem-Solving Training in Helping Long-Term Survivors of Hematopoietic Stem Cell Transplant Cope With Late Complications (NCT00799461)Fred Hutchinson Cancer Research Center/University of Washington Cancer Consortium2008-08-01
Lenalidomide and Alvocidib in Treating Patients With Relapsed or Refractory B-cell Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (NCT00735930)National Cancer Institute (NCI)2008-08-01
Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer (NCT00723099)Fred Hutchinson Cancer Center2008-06-25
Obatoclax, Fludarabine, and Rituximab in Treating Patients With Previously Treated Chronic Lymphocytic Leukemia (NCT00612612)National Cancer Institute (NCI)2008-01-01
Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies (NCT01093586)Case Comprehensive Cancer Center2007-09-01
Sunitinib in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma (NCT00398112)National Cancer Institute (NCI)2007-08-01
Genetically Engineered Lymphocytes, Cyclophosphamide, and Aldesleukin in Treating Patients With Relapsed or Refractory Mantle Cell Lymphoma or Indolent B-Cell Non-Hodgkin Lymphoma (NCT00621452)Fred Hutchinson Cancer Center2007-08-01
Beclomethasone Dipropionate in Preventing Acute Graft-Versus-Host Disease in Patients Undergoing a Donor Stem Cell Transplant for Hematologic Cancer (NCT00489203)Fred Hutchinson Cancer Center2007-04-01
Sunitinib in Treating Patients With Idiopathic Myelofibrosis (NCT00387426)National Cancer Institute (NCI)2006-09-01
Lower But More Frequent Dose Rituximab to Treat Chronic Lymphocytic Leukemia (NCT00366418)National Heart, Lung, and Blood Institute (NHLBI)2006-08-10
High-Dose Chemotherapy With or Without Total-Body Irradiation Followed by Autologous Stem Cell Transplant in Treating Patients With Hematologic Cancer or Solid Tumors (NCT00536601)Roswell Park Cancer Institute2006-06-29
Lithium Carbonate in Treating Patients With Acute Intestinal Graft-Versus-Host-Disease (GVHD) After Donor Stem Cell Transplant (NCT00408681)Fred Hutchinson Cancer Center2006-06-01
AZD2171 in Treating Patients With Relapsed or Refractory B-Cell Chronic Lymphocytic Leukemia (NCT00321724)National Cancer Institute (NCI)2006-05-01
A Pilot Study to Evaluate the Co-Infusion of Ex Vivo Expanded Cord Blood Cells With an Unmanipulated Cord Blood Unit in Patients Undergoing Cord Blood Transplant for Hematologic Malignancies (NCT00343798)Fred Hutchinson Cancer Center2006-04-01
SJG-136 in Treating Patients With Relapsed or Refractory Acute Leukemia, Myelodysplastic Syndromes, Blastic Phase Chronic Myelogenous Leukemia, or Chronic Lymphocytic Leukemia (NCT00301769)National Cancer Institute (NCI)2005-12-01
Sorafenib and Bortezomib in Treating Patients With Advanced Cancer (NCT00303797)National Cancer Institute (NCI)2005-12-01
Bevacizumab in Treating Patients With Relapsed or Refractory Chronic Lymphocytic Leukemia (NCT00290810)National Cancer Institute (NCI)2005-12-01
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