| Phase I Study of Linerixibat in Adults With Moderate Hepatic Impairment and Healthy Controls (NCT05393076) | GlaxoSmithKline | 2022-07-19 |
| A Clinical Trial Evaluating the Efficacy and Safety of HSK21542 in Patients with Chronic Kidney Disease-Associated Pruritus (NCT05135390) | Haisco Pharmaceutical Group Co., Ltd. | 2022-06-17 |
| A Study to Evaluate the Safety and Efficacy of Difelikefalin in Advanced Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus (NCT05342623) | Cara Therapeutics, Inc. | 2022-05-17 |
| Gabapentin Versus Loratadine in Uremic Pruritus (NCT05750875) | King Edward Medical University | 2022-05-01 |
| Bioavailability and Tolerability of Fexofenadine Hydrochloride Topical Lotion 1% (NCT05461456) | OrchestratePharma GmbH | 2022-04-01 |
| Efficacy and Safety of Subcutaneous Dupilumab for the Treatment of Adult Participants With Chronic Pruritus of Unknown Origin (CPUO) (LIBERTY-CPUO-CHIC) (NCT05263206) | Sanofi | 2022-02-15 |
| Health Belief Model-Based Education for Pruritus and Quality of Life in Hemodialysis Patients (NCT07641530) | Ege University | 2022-01-01 |
| Linerixibat and Obeticholic Acid Drug Interaction Study in Healthy Adult Participants (NCT05133830) | GlaxoSmithKline | 2021-11-23 |
| A Clinical Trial Evaluating the Efficacy, Safety, and Pharmacokinetics of HSK21542 Injection in Liver Disease Subjects With Pruritus (NCT04999787) | Haisco Pharmaceutical Group Co., Ltd. | 2021-09-16 |
| Efficacy of Abrocitinib for Reducing Pruritus in Adults With Prurigo Nodularis and Chronic Pruritus of Unknown Origin (NCT05038982) | Johns Hopkins University | 2021-09-09 |
| Global Linerixibat Itch Study of Efficacy and Safety in Primary Biliary Cholangitis (PBC) (GLISTEN) (NCT04950127) | GlaxoSmithKline | 2021-08-27 |
| Psychogenic and Neurogenic Components in Patients With Psychogenic or Neuropathic Pruritus (NCT05024851) | University Hospital, Brest | 2021-08-25 |
| Treatment of Pruritus With Intramuscular Promethazine (NCT04805073) | University of Florida | 2021-08-09 |
| The Efficacy of VR and AR on Pruritus (NCT04289038) | Hacettepe University | 2021-04-01 |
| Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Notalgia Paresthetica (KOMFORT) (NCT04706975) | Cara Therapeutics, Inc. | 2021-01-11 |
| Blue Light in the Treatment of Inflammatory Skin Diseases (NCT06516783) | Medical University of Lodz | 2020-11-27 |
| Enhanced Recovery After Cesarean Section With Low Dose Intrathecal Morphine. (NCT04618146) | Minia University | 2020-11-10 |
| Postoperative Pain After Caesarian Section (NCT05659823) | Conrad Arnfinn Bjørshol | 2020-11-02 |
| Adding Nalbuphine for Control of Intrathecal Morphine Pruritus (NCT04589429) | Minia University | 2020-10-15 |
| Treatment of Chronic Itch in Atopic Dermatitis With Topical Naltrexone (NCT04154033) | University of Minnesota | 2020-10-01 |
| Evaluate the Safety, Tolerability, and PK of EP547 in Healthy Subjects and Subjects With Cholestatic or Uremic Pruritus (NCT04510090) | Escient Pharmaceuticals, Inc | 2020-09-07 |
| Dupilumab for the Treatment of Moderate to Severe Chronic Hepatic Pruritus (NCT04256759) | Mayo Clinic | 2020-09-01 |
| The Effect of Propofol on Dexamethasone-induced Perineal Pruritus (NCT04337073) | Yangzhou University | 2020-09-01 |
| Prevalence of a Localized or Diffuse Pruritus in a Population With One or Several, Primitive or Secondary, Brain Tumor(s) (NCT03673878) | University Hospital, Brest | 2020-06-29 |
| B244 Topical Spray for the Treatment of Pruritus in Adults With a History of Atopic Dermatitis (NCT04490109) | AOBiome LLC | 2020-06-24 |
| A Study of SHR0410 in Hemodialysis Patients With Pruritus (NCT04317209) | Jiangsu HengRui Medicine Co., Ltd. | 2020-05-17 |
| Non-pharmacological Mitigation of Psoriasis (NCT04745429) | Medical University of Lodz | 2020-02-19 |
| The Effect of Midazolam on Dexamethasone-induced Perineal Pruritus (NCT04326738) | Yangzhou University | 2020-01-16 |
| Influence of H1-antihistamines on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin. (NCT04399525) | Universitaire Ziekenhuizen KU Leuven | 2019-10-28 |
| Pruritus and Melanoma and Cutaneous Carcinomas Treated With Immunotherapy (NCT04365244) | University Hospital, Brest | 2019-08-19 |
| Topical Acetaminophen for Itch Relief: a Proof of Concept Study in Healthy Subjects (NCT03997851) | University of Miami | 2019-07-22 |
| Study to Evaluate the Efficacy and Safety of Oral Difelikefalin (CR845) for Moderate to Severe Pruritus in Subjects With Atopic Dermatitis (NCT04018027) | Cara Therapeutics, Inc. | 2019-06-29 |
| Influence of Antipruritics on the Dermal Blood Flow Response to Histamine, Cinnamaldehyde and Capsaicin. (NCT04399148) | Universitaire Ziekenhuizen KU Leuven | 2019-06-11 |
| Frequency and Characteristics of Pruritus in Patients With Monoclonal Gammopathy (NCT03832140) | University Hospital, Brest | 2019-05-24 |
| Study Determining Safety and Efficacy of Avena Sativa (Oat) Skincare Products for Treating Skin Dryness and Itching in Cancer Patients (NCT03796052) | Johnson & Johnson Consumer Inc. (J&JCI) | 2019-05-23 |
| A Trial of SHR0410 Injection in Hemodialysis Participants. (NCT03857568) | Atridia Pty Ltd. | 2019-04-15 |
| Inter-arm and Inter-period Reproducability of the Dermal Blood Flow Response After a Histamine Skin Prick. (NCT04396977) | Universitaire Ziekenhuizen KU Leuven | 2019-02-28 |
| Study of the Efficacy, Safety, and Tolerability of Serlopitant for the Treatment of Chronic Pruritus of Unknown Origin (NCT03841331) | Vyne Therapeutics Inc. | 2019-01-22 |
| Dermal Blood Flow Response to Escalating Doses of Histamine, Administered by a Skin Prick (NCT04399213) | Universitaire Ziekenhuizen KU Leuven | 2019-01-15 |
| Study to Evaluate ASN008 Topical Gel (TG) (NCT03798561) | Asana BioSciences | 2019-01-14 |
| Study Evaluating the Benefit of Music Therapy on Pruritus in Patients With Pruritic Dermatitis (NCT03701971) | University Hospital, Brest | 2018-11-08 |
| Enhancing SKIN Health and Safety in Aged CARE (NCT03824886) | PD Dr. Jan Kottner | 2018-10-01 |
| Scalp Pruritus Measurement Using Visual Analog Scale and 5-d Itch Scale in Children With Pediculosis Capitis (NCT04415034) | Indonesia University | 2018-09-01 |
| Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Prurigo Nodularis (NCT03677401) | Vyne Therapeutics Inc. | 2018-08-29 |
| Scratch and Sleep Quantification in Atopic Dermatitis (NCT03490877) | University of Rochester | 2018-07-13 |
| A Study to Evaluate the Safety and Efficacy of CR845 in Chronic Kidney Disease Patients With Moderate-to-Severe Pruritus (NCT03617536) | Cara Therapeutics, Inc. | 2018-07-05 |
| Effect of Granisetron on Morphine Induced Pruritus in Cesarean Section (NCT03483870) | Assiut University | 2018-06-01 |
| Study of the Efficacy, Safety and Tolerability of Serlopitant for the Treatment of Pruritus (Itch) With Prurigo Nodularis (NCT03546816) | Vyne Therapeutics Inc. | 2018-05-02 |
| A Study of the Efficacy and Safety of Orvepitant in Subjects With Pruritus Associated With Atopic Dermatitis (NCT03464526) | Nerre Therapeutics Ltd. | 2018-05-01 |
| Study of the Long Term Safety of Serlopitant for the Treatment of Pruritus (Itch) (NCT03540160) | Vyne Therapeutics Inc. | 2018-03-15 |
| Acupuncture for Prevention of Itch in Caesarean Section (NCT03458572) | Sheffield Teaching Hospitals NHS Foundation Trust | 2018-02-12 |
| Does IV Ondansetron Prevent Pruritus After Intrathecal Morphine in Pediatric Patients? (NCT03262038) | University of Michigan | 2017-12-07 |
| Safety, Efficacy, and Tolerability of SNA-120 in Subjects With Pruritus Associated With Psoriasis Vulgaris (NCT03322137) | Sienna Biopharmaceuticals | 2017-10-10 |
| Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocaine (NCT03096444) | Gil Yosipovitch | 2017-05-23 |
| Evaluate the Efficacy and Safety of HL151 Versus Talion Tab. in Pruritus Cutaneus (NCT03317301) | Hanlim Pharm. Co., Ltd. | 2017-05-17 |
| Desensitization of Nociceptive Afferents by Application of Topical Capsaicin, Trans-cinnamaldehyde and L-menthol (NCT03132142) | Aalborg University | 2017-04-01 |
| The Color of Itch; Itch Modification by Color Viewing (NCT03928223) | University Hospital, Basel, Switzerland | 2017-03-01 |
| In-Use Test With a Cosmetic Product to Treat Pruritus (NCT03477058) | Dr. August Wolff GmbH & Co. KG Arzneimittel | 2017-01-23 |
| Quality of Recovery After Dexamethasone, Ondansetron or Placebo Intrathecal Morphine Administration (NCT03035942) | Pontificia Universidade Catolica de Sao Paulo | 2017-01-02 |
| Study of the Efficacy, Safety & Tolerability of Serlopitant for Pruritus (Itch) After Burn Injury (NCT02975271) | Vyne Therapeutics Inc. | 2016-11-01 |
| Neurokinin-1 Receptor Antagonist for the Treatment of Itch in EB Patients (NCT02654483) | Jean Yuh Tang | 2016-08-31 |
| A Study to Assess the Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-SK-1405 (NCT02846181) | Sanwa Kagaku Kenkyusho Co., Ltd. | 2016-07-01 |
| Pruritus and Pemphigoid in Nursing Home Patients (NCT02823067) | M.F. Jonkman | 2016-06-01 |
| Ondansetron vs Ondansetron Plus Dexamethasone for Relieving Intrathecal Morphine Side Effects After C-section (NCT02793843) | Makassed General Hospital | 2016-06-01 |
| Effects of High-concentration Topical Capsaicin on Histaminergic and Non-histaminergic Itch (NCT02769910) | Hjalte Holm Andersen | 2016-05-01 |
| Itch Relieving Effect of Botox: a Study in Healthy Subjects (NCT02639052) | Temple University | 2016-02-01 |
| Itch and Clinacal Caracteristics in Systemic Sclerosis (NCT03297580) | University Hospital, Brest | 2016-02-01 |
| A Study to Investigate the Receptor Occupancy of SK-1405 in Healthy, Caucasian, Male Subjects (NCT02650076) | Sanwa Kagaku Kenkyusho Co., Ltd. | 2016-01-01 |
| Evaluating the Effect of Fumaria Parviflora L. in Uremic Pruritus (NCT02671162) | Shiraz University of Medical Sciences | 2015-07-01 |
| Safety, Pharmacokinetics and Preliminary Efficacy of Asimadoline in Pruritus Associated With Atopic Dermatitis (NCT02475447) | Tioga Pharmaceuticals | 2015-07-01 |
| Non Interventional Clinical Investigation of Ectoin Ear Spray in Skin Treatment of Outer Ear Canal Irritations (NCT02558738) | Bitop AG | 2015-06-22 |
| Itch and Pain Characteristics in Skin Carcinomas (NCT03290989) | University Hospital, Brest | 2015-04-01 |
| Study of Nalbuphine HCl ER Tablets in Patients With Prurigo Nodularis (NCT02174419) | Trevi Therapeutics | 2015-03-01 |
| Impact of Vorinostat on Pruritus Signaling Pathways - Merck Study (NCT01801670) | Boston University | 2015-01-01 |
| L-menthol as a Topical Counter-irritant to TRPA1-induced Neurogenic Inflammation and Pain (NCT02653703) | Aalborg University | 2014-10-01 |
| Efficacy of Laser Acupuncture on Pruritus in Patients With Chronic Kidney Disease Undergoing Hemodialysis (NCT02432508) | China Medical University Hospital | 2014-10-01 |
| Study of Using Long Acting Antihistamine to Treat Opioid Induced Itching (NCT01825655) | Virginia Commonwealth University | 2014-09-01 |
| Safety and Pharmacokinetics of IV CR845 in Hemodialysis Patients, and Its Efficacy in Patients With Uremic Pruritus (NCT02229929) | Cara Therapeutics, Inc. | 2014-07-01 |
| Serum Serotonin and Pruritus After Intrathecal Morphine in Cesarean Section (NCT03209427) | Assiut University | 2014-04-02 |
| Topical Aprepitant in Prurigo Patients (NCT01963793) | LEO Pharma | 2013-10-01 |
| Study of Itch Control by VLY-686 in Healthy Volunteers After Intradermal Injections of Substance P (NCT01919944) | Vanda Pharmaceuticals | 2013-08-01 |
| Comparison of Epidural Oxycodone and Epidural Morphine (NCT02277678) | KK Women's and Children's Hospital | 2013-08-01 |
| Blinded, Randomized Study Evaluating Aurstat Versus Control in the Treatment of Atopic Dermatitis Associated Pruritus (NCT01905631) | The Center for Clinical and Cosmetic Research | 2013-07-01 |
| Efficacy of Extended-release, Once Daily Tramadol for Post Operative Analgesia in Shoulder Arthroscopy (NCT02247648) | Centre hospitalier de l'Université de Montréal (CHUM) | 2013-06-01 |
| Effects of Transcranial Direct Current Stimulation (tDCS) on Neuropathic Symptoms Following Burn Injury (NCT01795079) | Spaulding Rehabilitation Hospital | 2013-01-01 |
| Study to Assess the Clinical Activity of a Sequential Dose of REGN846 on Refractory Pruritus in Patients With Atopic Dermatitis (NCT01605708) | Regeneron Pharmaceuticals | 2012-06-01 |
| Effect of Neurokinin-1 Receptor (NK1R) Antagonism on Pruritus in Patients With Sezary Syndrome (NCT01625455) | Vanderbilt University Medical Center | 2012-02-01 |
| Evaluating the Effect of Senna in Uremic Pruritus (NCT02008864) | Shiraz University of Medical Sciences | 2011-08-01 |
| Pruritus in Patients With Chronic Kidney Disease (NCT01727180) | Far Eastern Memorial Hospital | 2011-06-01 |
| PK Comparisons of Bepotastine Besilate 10 mg and Bepotastine Salicylate 9.64 mg (NCT01897428) | Korea University Anam Hospital | 2011-04-01 |
| Safety Study of Levocetirizine and Fexofenadine (NCT01586091) | Charite University, Berlin, Germany | 2011-02-01 |
| Explore the Mechanisms of Pruritus in Bullous Pemphigoid Patients During Remission (NCT01265082) | National Taiwan University Hospital | 2010-12-01 |
| Naloxone for the Treatment of Opioid-Induced Pruritus (NCT01071057) | University of British Columbia | 2010-12-01 |
| Efficacy and Tolerability Study of Device, RD047-26 for the Treatment of Mild to Moderate Atopic Dermatitis in Adults (NCT01232985) | Oculus Innovative Sciences, Inc. | 2010-10-01 |
| Gabapentin for Prophylaxis Intrathecal Morphine-Induced Pruritus (NCT01236859) | Prince of Songkla University | 2009-09-01 |
| Intrathecal Morphine for Inguinal Hernia Repair. (NCT02001948) | Ankara University | 2009-07-01 |
| Gabapentin for the Treatment of Pruritus Caused by Burn Injuries in Children (NCT01092520) | The Hospital for Sick Children | 2009-07-01 |
| Evaluating the Effect of Cromolyn Sodium in Uremic Pruritus (NCT00745199) | Shiraz University of Medical Sciences | 2008-05-01 |
| Hydroxyzine for the Prevention of Pruritus From Spinal Morphine in Transabdominal Hysterectomy Patients (NCT01055236) | Mahidol University | 2007-08-01 |
| Evaluation of Post Burn Rehabilitation Population for Itch Control (NCT00782054) | Swiss-American Products, Inc | 2006-09-01 |