Atlas Trials

Primary Progressive Multiple Sclerosis

38 clinical trials · Condition

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RecordFirmDate
The Influence of HIIT Versus MCT on Cardiorespiratory Fitness in PPMS (NCT05229861)Klinik Valens2022-05-10
A Phase III, Non-Inferiority, Randomized, Open-Label, Parallel Group, Multicenter Study To Investigate The Pharmacokinetics, Pharmacodynamics, Safety And Radiological And Clinical Effects Of Subcutaneous Ocrelizumab Versus Intravenous Ocrelizumab In Patients With Multiple Sclerosis (NCT05232825)Hoffmann-La Roche2022-05-03
Metformin Treatment in Progressive Multiple Sclerosis (NCT05349474)University of California, Los Angeles2022-04-26
Gray Matter Demyelination in Primary Progressive MS at 7T (NCT04977622)Danish Research Centre for Magnetic Resonance2021-11-30
Phase 1b Multiple Ascending Dose Study of Foralumab in Primary and Secondary Progressive MS (NCT05029609)Tiziana Life Sciences LTD2021-10-01
Non-inferiority Study of Ocrelizumab and Rituximab in Active Multiple Sclerosis (NCT04688788)Rigshospitalet, Denmark2021-04-28
Intrathecal Administration of DUOC-01 in Adults With Primary Progressive Multiple Sclerosis (NCT04943289)Joanne Kurtzberg, MD2021-01-24
SIZOMUS Safety of Ixazomib Targeting Plasma Cells in Multiple Sclerosis (NCT03783416)Queen Mary University of London2020-06-15
Effect of Ocrelizumab on Brain Innate Immune Microglial Cells Activation in MS Using PET-MRI With 18F-DPA714 (NCT03691077)Assistance Publique - Hôpitaux de Paris2018-11-11
Upper Extremity Function in Multiple Sclerosis Patients With Advanced Disability Treated With Ocrevus (NCT03562975)University of South Florida2018-07-23
Comparing Tolerability and Absorption of Racemic and R-lipoic Acid in Progressive Multiple Sclerosis (NCT03493841)Rebecca Spain2018-06-08
Safety and Efficacy of Monthly Long-acting IM Injection of 25mg or 40 mg GA Depot in Subjects With PPMS (NCT03362294)Mapi Pharma Ltd.2017-12-11
Phase 1/2 Study to Evaluate the Safety and Efficacy of ATA188 in Subjects With Progressive Multiple Sclerosis (NCT03283826)Atara Biotherapeutics2017-10-19
Dimethyl Fumarate Treatment of Primary Progressive Multiple Sclerosis (NCT02959658)Rigshospitalet, Denmark2016-12-01
Video Game-based Therapy for Arm Weakness In Progressive Multiple Sclerosis (NCT03094364)University of Massachusetts, Lowell2015-11-01
Mitochondrial Dysfunction and Disease Progression (NCT02549703)Icahn School of Medicine at Mount Sinai2015-09-01
A Phase 2 Clinical Study in Subjects With Primary Progressive Multiple Sclerosis to Assess the Efficacy, Safety and Tolerability of Two Oral Doses of Laquinimod Either of 0.6 mg/Day or 1.5mg/Day (Experimental Drug) as Compared to Placebo (NCT02284568)Teva Branded Pharmaceutical Products R&D, Inc.2015-01-12
A Phase 1 Trial of Intrathecal Rituximab for Progressive Multiple Sclerosis Patients (NCT02253264)Johns Hopkins University2014-11-01
Efficacy, Safety and Tolerability of Andrographolides Versus Placebo in Patients With Progressive Forms of MS (NCT02273635)Innobioscience SpA2014-09-01
ACTH in Progressive Forms of MS (NCT01950234)University of Minnesota2014-04-17
A Study of the Effectiveness of Fampridine in Improving Upper Limb Function in MS (NCT02208050)University College Dublin2014-02-21
Serial Collection of Primary Progressive Multiple Sclerosis Participants in the MURDOCK Study (NCT01776060)Duke University2013-01-01
Estriol Treatment in Multiple Sclerosis (MS): Effect on Cognition (NCT01466114)University of California, Los Angeles2011-10-01
Tear Analysis in the Diagnosis of Multiple Sclerosis (NCT02016222)Lille Catholic University2011-04-01
Safety Study of an Immunomodulating Microparticle to Treat Progressive Multiple Sclerosis (NCT01191996)Innate Immunotherapeutics2010-08-01
Natalizumab Treatment of Progressive Multiple Sclerosis (NCT01077466)Rigshospitalet, Denmark2010-03-01
This Was an Open-label, Single-arm Extension Study (CFTY720D2306E1) to a Double-blind, Randomized Multicenter, Placebo-controlled, Parallel-group Core Study (CFTY720D2306) in PPMS. (NCT00731692)Novartis Pharmaceuticals2008-07-28

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