| Study to Evaluate the Safety, Tolerability, PK Characteristics and Anti-tumor Activity of FCN-159 in Adult and Pediatric Participants With Neurofibromatosis Type 1 (NCT04954001) | Shanghai Fosun Pharmaceutical Industrial Development Co. Ltd. | 2021-03-26 |
| MEK Inhibitor Mirdametinib (PD-0325901) in Patients With Neurofibromatosis Type 1 Associated Plexiform Neurofibromas (NCT03962543) | SpringWorks Therapeutics, Inc., a healthcare company of Merck KGaA, Darmstadt, Germany | 2019-09-29 |
| Intermittent Dosing Of Selumetinib In Childhood NF1 Associated Tumours (NCT03326388) | Great Ormond Street Hospital for Children NHS Foundation Trust | 2019-09-26 |
| A Retrospective Study on Epidemiological Characteristics of Chinese NF1 Patients in Real World (PROMISE) (NCT06379230) | Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University | 2019-01-01 |
| Trametinib for Pediatric Neuro-oncology Patients With Refractory Tumor and Activation of the MAPK/ERK Pathway. (NCT03363217) | St. Justine's Hospital | 2018-08-16 |
| Whole Body MRI to Identify Atypical Neurofibromas in Patients With NF1 (NCT03820778) | Children's National Research Institute | 2018-07-12 |
| Phase II Study of Binimetinib in Children and Adults With NF1 Plexiform Neurofibromas (NCT03231306) | University of Alabama at Birmingham | 2017-11-28 |
| Use of RAD001 as Monotherapy in the Treatment of Neurofibromatosis 1 Related Internal Plexiform Neurofibromas (NCT01412892) | Assistance Publique - Hôpitaux de Paris | 2011-04-01 |
| Sorafenib to Treat Children and Young Adults With Neurofibromatosis Type 1 and Inoperable Plexiform Neurofibromas (NCT00727233) | National Cancer Institute (NCI) | 2008-07-08 |
| Natural History Study of Patients With Neurofibromatosis Type I (NCT00924196) | National Cancer Institute (NCI) | 2008-02-25 |
| Study of PEG-Intron for Plexiform Neurofibromas (NCT00396019) | University of Pittsburgh | 2006-12-01 |
| AZD2171 in Treating Patients With Neurofibromatosis Type 1 and Plexiform Neurofibroma and/or Neurofibroma Near the Spine (NCT00326872) | National Cancer Institute (NCI) | 2006-05-01 |