| Safety and Efficacy of IrisFIT™ Patent Foramen Ovale Occluders (NCT05312554) | Lifetech Scientific (Shenzhen) Co., Ltd. | 2022-04-12 |
| Assessment of Flecainide to Lower the Patent Foramen Ovale Closure Risk of Atrial Arrhythmia or Tachycardia (NCT05213104) | Assistance Publique - Hôpitaux de Paris | 2022-03-23 |
| Philips Intracardiac Echocardiography (ICE) Clinical Registry (NCT04950192) | Philips Clinical & Medical Affairs Global | 2021-10-25 |
| Prevalence of Atrial Fibrillation in Cryptogenic Stroke With Patent Foramen Ovale Closure (PFO-AF) Study (NCT04926142) | Centre Hospitalier Universitaire de Besancon | 2021-07-05 |
| Patent Foramen Ovale Closure in Older Patients (NCT04780022) | Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec | 2021-04-01 |
| GORE® CARDIOFORM Septal Occluder Migraine Clinical Study (NCT04100135) | W.L.Gore & Associates | 2021-02-05 |
| Internal Microstructure of Patent Foramen Ovale Related to Stroke (NCT04686253) | China National Center for Cardiovascular Diseases | 2020-12-23 |
| RoBotic TCD Ultrasound BubbLe Study Compared to Transthoracic Echocardiography for Detection of Right to Left Shunt (NCT04604015) | NeuraSignal Inc dba NovaSignal | 2020-10-06 |
| Evaluation of the Severity of Right to Left Shunt in PFO Patients After Systemic Embolism (NCT04610463) | University Hospital Hradec Kralove | 2020-09-25 |
| Discontinuation of Antithrombotic Treatment Following Patent Foramen Ovale Closure in Young Patients With Cryptogenic Stroke (NCT04475510) | Josep Rodes-Cabau | 2020-07-08 |
| Canadian Adult Congenital Heart Disease Intervention Registry (NCT04288596) | University Health Network, Toronto | 2020-04-01 |
| Post Market Registry of the CBSO (NCT04105595) | atHeart Medical | 2020-03-05 |
| PFO Occlusion and Atrial Fibrillation (NCT04898361) | University Hospital, Saarland | 2020-01-15 |
| International Multicenter Patent foRamen OVale & strokE (IMPROVE) Registry (NCT04738071) | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2019-11-13 |
| Is Blood Flow Through IPAVA and PFO Related to Breath-hold and SCUBA Diving-induced Pulmonary Hypertension? (NCT03945643) | University of Oregon | 2019-07-01 |
| Evaluation of the Efficacy and Safety of a Simplified Procedure for the Percutaneous Closure of the Patent Foramen Ovale (NCT03828825) | Fondation Hôpital Saint-Joseph | 2019-02-01 |
| Does Patent Foramen Ovale Size Matter in Men and Women (NCT03904277) | University of Oregon | 2018-10-01 |
| Does Patent Foramen Ovale Closure Improve Exercise Capacity & Prevent Blood Flow Through Intrapulmonary Shunt (NCT03904290) | University of Oregon | 2018-04-05 |
| AMPLATZER PFO Occluder Post Approval Study (NCT03309332) | Abbott Medical Devices | 2018-01-31 |
| Precutaneous High Risk Patent Foramen Ovale to Treat Migraine Headaches (NCT02777359) | First Affiliated Hospital Xi'an Jiaotong University | 2017-01-01 |
| Patent Foramen Ovale Closure Reduce in SCUBA-divers (NCT03997084) | Skane University Hospital | 2017-01-01 |
| Biomarkers, Hemodynamic and Echocardiographic Predictors of Ischemic Strokes and Their Influence on the Course and Prognosis (NCT03377465) | Medical University of Lodz | 2016-11-15 |
| Anticoagulants for PFO Patients (NCT06375070) | Xuanwu Hospital, Beijing | 2016-08-01 |
| Lifetech CeraFlex™ Post-Market Surveillance Study (NCT02621528) | Lifetech Scientific (Shenzhen) Co., Ltd. | 2015-10-01 |
| Influence of Position on Detection of Patent Foramen Ovale by Simultaneous Transesophageal Echo and Transcranial Doppler (NCT02383836) | Hillel Yaffe Medical Center | 2015-03-01 |
| Residual Shunt After Patent Foramen Ovale Device Closure in Patients With Cryptogenic Stroke (NCT03416426) | Gachon University Gil Medical Center | 2014-03-28 |
| Nitrogen Bubble Detection After Simulated Dives in Divers With PFO and After PFO Closure (NCT01854281) | University Hospital, Motol | 2013-05-01 |
| PFO Closure for Obstructive Sleep Apnoea (NCT02771561) | Papworth Hospital NHS Foundation Trust | 2013-04-01 |
| Right to Left Cardiac Shunt Detection (NCT01773252) | Cardiox Corporation | 2012-11-01 |
| Cardiox Shunt Detection Technology Study (NCT01333761) | Cardiox Corporation | 2011-04-01 |
| Nickel Allergy With Septal Closure Devices (NCT01068366) | University of Utah | 2010-02-01 |
| Comorbidities Associated With Migraine and Patent Foramen Ovale (CAMP) (NCT01257880) | Swedish Medical Center | 2010-01-01 |
| Pulmonary Embolism and Stroke in Patient With Patent Foramen Ovale (NCT01216423) | University Hospital, Brest | 2009-11-01 |
| The Effect of Device Closure of Patent Foramen Ovale in Elderly Patients With Crytogenic Stoke/TCI (NCT01018355) | Hillerod Hospital, Denmark | 2009-10-01 |
| Patent Foramen Ovale Closure or Anticoagulants Versus Antiplatelet Therapy to Prevent Stroke Recurrence (NCT00562289) | Assistance Publique - Hôpitaux de Paris | 2007-12-01 |
| Risk of Stroke in Pulmonary Embolism With a Patent Foramen Ovale (PFO) (NCT00831259) | University Hospital, Caen | 2007-10-01 |
| PRIMA PFO Migraine Trial (NCT00505570) | Abbott Medical Devices | 2006-05-01 |
| PFx Closure System in Subjects With Cryptogenic Stroke,Transient Ischemic Attack,Migraine or Decompression Illness(PFO) (NCT00335296) | Cierra | 2006-05-01 |
| MIST II PFO-Migraine Trial With BioSTAR® Bioabsorbable Septal Repair Implant (NCT00283738) | NMT Medical | 2006-02-01 |
| PREMIUM Migraine Trial (NCT00355056) | Abbott Medical Devices | 2006-01-01 |
| Paradigm I Clinical Trial: Study of the PFX Closure System in Subjects With Cryptogenic Stroke, Transient Ischemia Attack or Paradoxical Embolism (NCT00196027) | Cierra | 2005-04-01 |
| Evaluation of the STARFlex® Septal Closure System in Patients With a Stroke or TIA Due to the Possible Passage of a Clot of Unknown Origin Through a Patent Foramen Ovale (PFO) (NCT00201461) | NMT Medical | 2003-06-01 |
| PFO tRanscatether Occlusion Long-term Outcomes National Group (PROLONG) Registry (NCT06504121) | IRCCS Ospedale San Raffaele | 1999-01-01 |
| Patent Foramen Ovale in Cryptogenic Stroke Study (NCT00697151) | Columbia University | 1993-06-01 |
| Emergency/Compassionate Use PFO Occluder (NCT00584064) | Abbott Medical Devices | |
| Safety and Effectiveness Study of the Solysafe Septal Occluder in Patients With Atrial Septum Defect and Patent Foramen Ovale (NCT00207376) | Carag AG | |