| Post Marketing Clinical Follow Up Study to Evaluate Efficacy and Safety of the Occlutech PDA Occluder in Patients With Patent Ductus Arteriosus Defects (NCT05264753) | Occlutech International AB | 2021-12-20 |
| PAIR (Paracetamol and Ibuprofen Research) Pilot Trial (NCT04986839) | Manchester University NHS Foundation Trust | 2021-09-03 |
| Optimal Dose of Surfactant for Preterm Infants With Respiratory Distress Syndrome (NCT04984057) | Daping Hospital and the Research Institute of Surgery of the Third Military Medical University | 2021-08-01 |
| Aminoglycosides and Duct (NCT04415554) | Carmel Medical Center | 2021-07-01 |
| Effect of PDA Closure on the Left Ventricular Remodeling (NCT04964531) | Ahmed Mohamed Moheb El-Din | 2021-07-01 |
| Addition of Acetaminophen in Standard PDA Management (NCT04026464) | University of Florida | 2021-04-01 |
| Clinical Profile of Neonates Having Patent Ductus Arteriosus (NCT04672629) | Assiut University | 2021-04-01 |
| Preliminary Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low-weight Infants (NCT03982342) | Nationwide Children's Hospital | 2020-10-10 |
| Ibuprofen vs Expectant Management for hsPDA in Preterm Infants: Retrospective Cohort (NCT07533721) | Shengjing Hospital | 2020-06-01 |
| Population Pharmacokinetics and Dosage Individualization of Paracetamol and Ibuprofen in Children With PDA (NCT04397913) | Shandong University | 2020-05-25 |
| Amplatzer Piccolo Occluder Japan Post-marketing Database Surveillance (NCT04371081) | Abbott Medical Devices | 2020-04-01 |
| Improving Care for Children With Congenital Heart Disease. (NCT04667455) | Lund University Hospital | 2020-02-17 |
| Canadian National PDA Treatment Study (NCT04347720) | IWK Health Centre | 2020-01-01 |
| Timing of Surgical PDA Ligation and Neonatal Outcomes (NCT04126512) | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 2019-09-25 |
| Early Prediction of Spontaneous Patent Ductus Arteriosus (PDA) Closure and PDA-Associated Outcomes (NCT03782610) | Nationwide Children's Hospital | 2019-04-01 |
| Management of the PDA Trial (NCT03456336) | NICHD Neonatal Research Network | 2019-02-22 |
| Early Treatment Versus Expectant Management of PDA in Preterm Infants (NCT03860428) | Lviv National Medical University | 2019-02-15 |
| A NEW SCORING SYSTEM FOR PREDICTION OF PDA (NCT04270240) | Kanuni Sultan Suleyman Training and Research Hospital | 2019-01-15 |
| Randomized Controlled Trial to Evaluate the Safety and Efficacy of Acetaminophen in Preterm Infants Used in Combination With Ibuprofen for Closure of the Ductus Arteriosus (NCT03701074) | University of South Alabama | 2018-12-15 |
| Feasibility, Efficacy and Safety of IBS ® for Implantaiton in the PDA in Duct-dependent Cyanotic CHD (NCT04291222) | Lifetech Scientific (Shenzhen) Co., Ltd. | 2018-12-11 |
| Paracetamol And Ibuprofen/Indomethacin in Closing Patent Ductus Arteriosus (NCT03648437) | University of Oulu | 2018-09-03 |
| Hemodynamic Responses to Cardio-respiratory Events in Preterm Infants (NCT04184245) | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 2018-02-22 |
| Treatment of a PDA With Acetaminophen in Preterm Neonates: Exploring Various Indications (NCT03289390) | Albany Medical College | 2017-08-01 |
| MISA to NRDS：a Multicenter Study in China (NCT04077333) | Peking University Third Hospital | 2017-07-01 |
| Combination of Acetaminophen and Ibuprofen in the Management of Patent Ductus Arteriosus (NCT03103022) | University of Florida | 2017-06-12 |
| AMPLATZER Duct Occluder II Additional Sizes (NCT03055858) | Abbott Medical Devices | 2017-06-05 |
| IV Acetaminophen and Patent Ductus Arteriosus (NCT03008876) | Albany Medical College | 2017-01-01 |
| International Experience in Timing And Choices for Ductal Closure in Patent Ductus Arteriosus:INTERPDA Trial (NCT02910609) | Ankara University | 2017-01-01 |
| Early Treatment Versus Expectative Management of PDA in Preterm Infants (NCT02884219) | Radboud University Medical Center | 2016-12-23 |
| Near Infrared Spectroscopy to Determine Patent Ductus Arteriosus Closure (NCT03026192) | Albany Medical College | 2016-12-01 |
| Acetaminophen vs Indomethacin in Treating hsPDA (NCT03537144) | University of Tennessee | 2016-06-01 |
| Paracetamol Treatment of the Borderline Significant PDA (NCT02819414) | Shaare Zedek Medical Center | 2016-06-01 |
| PDA Post NICU Discharge (NCT02750228) | Pediatrix | 2016-05-01 |
| Platelet Transfusion for Treatment of Patent Ductus Arteriosus in Thrombocytopenic Preterm Neonates (NCT03022253) | Post Graduate Institute of Medical Education and Research, Chandigarh | 2016-03-01 |
| Lifetech CeraFlex™ Post-Market Surveillance Study (NCT02621528) | Lifetech Scientific (Shenzhen) Co., Ltd. | 2015-10-01 |
| Splanchnic and Renal Tissue Oxygenation During Enteral Feedings in Neonates With Patent Ductus Arteriosus (NCT03551600) | University of Utah | 2015-10-01 |
| Paracetamol Versus Ibuprofen for PDA Closure (NCT03265782) | Ain Shams University | 2015-06-01 |
| Non-Invasive Detection of Tissue Oxygen Deprivation in Premature Infants With Patent Ductus Arteriosus. (NCT03277768) | University of Florida | 2015-05-01 |
| Radiation-Free Heart Catheterization Using MRI (NCT02739087) | Joshua Kanter | 2015-03-01 |
| Plethismographic Perfusion Index in Neonates (NCT02380040) | Shaare Zedek Medical Center | 2015-03-01 |
| Early Treatment Versus Delayed Conservative Treatment of the Patent Ductus Arteriosus (NCT01958320) | University of California, San Francisco | 2013-12-01 |
| Patent Ductus Arteriosus and Splanchnic Oxygenation at First Feed (NCT03723889) | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 2013-11-01 |
| Pocket Echocardiography System (PES) for Detection of PDA in Neonates (NCT01790750) | University of Florida | 2013-02-01 |
| Paracetamol and Patent Ductus Arteriosus (PDA) (NCT01291654) | Shaare Zedek Medical Center | 2012-04-01 |
| Early Ibuprofen Treatment of Patent Ductus Arteriosus (PDA) in Premature Infants (TRIOCAPI) (NCT01630278) | Nantes University Hospital | 2012-03-01 |
| Oral Paracetamol Versus Oral Ibuprofen in Management of Patent Ductus Arteriosus in Preterm Infants: A Randomised Controlled Trial (NCT01536158) | Zekai Tahir Burak Women's Health Research and Education Hospital | 2012-02-01 |
| Serum Level Measurement of Oral Paracetamol and Oral Ibuprofen for Patent Ductus Arteriosus Treatment in Preterm Infants (NCT01544972) | Zekai Tahir Burak Women's Health Research and Education Hospital | 2012-02-01 |
| Safety and Effectiveness Study With a New PDA Occluder for Closure of Patent Ductus Arteriosus (NCT01479218) | Occlutech International AB | 2011-11-01 |
| Influence of Treatment for Patent Ductus Arteriosus on Cerebral Oxygenation in Preterm Infants (NCT01428180) | University of Ulm | 2011-04-01 |
| Safety and Efficacy of Ibuprofen in Term Newborns With Patent Ductus Arteriosus (PDA) (NCT01511887) | Hormozgan University of Medical Sciences | 2011-01-01 |
| Impact of Maternal-infant Therapeutics on Safety, Mortality, and Disability (NCT01028183) | Duke University | 2010-08-01 |
| Second Course of Therapy for Resistant Patent Ductus Arteriosus (PDA) (NCT01070745) | Shaare Zedek Medical Center | 2010-06-01 |
| Safety/Efficacy Study of Optimizing Ibuprofen Dosing to Achieve Higher PDA Closure Rates (NCT00961753) | OSF Healthcare System | 2009-08-01 |
| Echocardiographically Guided Versus Standard Ibuprofen Treatment for Patent Ductus Arteriosus (NCT01593163) | Fundacion para la Investigacion Biomedica del Hospital Universitario la Paz | 2009-05-01 |
| Early Versus Late Use of Ibuprofen for Patent Ductus Arteriosus (PDA) Closure (NCT00833365) | University of Utah | 2009-01-01 |
| Efficacy and Safety of Oral Versus Intravenous Ibuprofen for PDA Treatment in ELBW Infants (NCT01261117) | Zekai Tahir Burak Women's Health Research and Education Hospital | 2009-01-01 |
| Timing for the Medical Treatment of Patent Ductus Arteriosus in Preterm Infants (NCT00795990) | University of Utah | 2008-11-01 |
| An Escalating Dose Indomethacin for the Treatment of Persistent Patent Ductus Arteriosus (PDA) In Preterm Infants (NCT00750581) | University of Calgary | 2008-08-01 |
| AMPLATZER Duct Occluder II Clinical Study (NCT00713700) | Abbott Medical Devices | 2008-08-01 |
| Feeding During Ibuprofen or Indomethacin Treatment of Preterm Infants (NCT00728117) | University of California, San Francisco | 2008-07-01 |
| Treating the Resistant Patent Ductus Arteriosus (PDA) (NCT00616382) | Shaare Zedek Medical Center | 2008-03-01 |
| Brain, Gut and Kidney Blood Flow During Medical Closure of PDA (NCT00554307) | University of Louisville | 2007-11-01 |
| Timing of PDA Closure and Respiratory Outcome in Premature Infants (NCT00802685) | University of Miami | 2007-11-01 |
| Closure of Patent Ductus Arteriosus With Indomethacin or Ibuprofen in Extreme Low Birth Weight Infants (NCT01758913) | Taipei Medical University Hospital | 2007-02-01 |
| Comparative Study of Efficacy and Safety of Oral Ibuprofen and Intravenous Ibuprofen in Closure of Patent Ductus Arteriosus in Very Low Birth Weight Infants (NCT00642330) | Hopital La Rabta | 2007-01-01 |
| Curosurf and Survanta Treatment(CAST)of RDS in Very Premature Infants (NCT00767039) | Alan Fujii | 2005-01-01 |
| Ibuprofen and Renal Function in Premature Infants (NCT00217191) | Maternite Regionale Universitaire | 2004-09-01 |
| The Use of B-type Natriuretic Peptide (BNP) to Predict Closure of a Patent Ductus Arteriosus (PDA) in Premature Infants (NCT00500305) | University of Virginia | 2004-04-01 |
| Comparison of 2 Different Indomethacin Dosing Protocols to Treat Infants Delivered at <28 Weeks Gestation With a Persistent Patent Ductus Arteriosus (NCT00187447) | University of California, San Francisco | 2003-08-01 |
| Safety and Efficacy Study of Ibuprofen l-Lysine Solution in Premature Infants for Treatment of PDA (NCT00440804) | Farmacon | 2002-12-01 |
| Ibuprofen vs. Continuous Indomethacin in the Treatment of PDA (NCT00485160) | Shaare Zedek Medical Center | 2002-02-01 |
| Nitric Oxide, Endothelin-1, and the Patency of Ductus Arteriosus in Preterm Infants (NCT00162903) | National Taiwan University Hospital | 2002-01-01 |
| Long Term Results of 450 Percutaneous Closures of PDA in a Single Center (NCT01929733) | Rambam Health Care Campus | 1998-01-01 |