| Bone Marrow Aspirate Concentrate (BMAC) vs Corticosteroid Injection (NCT05985785) | Rush University Medical Center | 2022-07-19 |
| ATTUNE Cementless FB Tibial Base Clinical Study (NCT04630262) | DePuy Orthopaedics | 2022-05-09 |
| A Pragmatic Trial to Determine the Benefit of Behaviorally Enhanced Exercise Incentives and Corticosteroid Injections in Osteoarthritis of the Knee Marching On for Veterans With Osteoarthritis of the Knee (NCT05035810) | VA Office of Research and Development | 2022-03-14 |
| Cannabinoid Interactions With Central and Peripheral Pain Mechanisms in Osteoarthritis of the Knee (NCT04992624) | Steven E Harte, PhD | 2022-02-22 |
| Identification of Sarcopenia in Knee Osteoarthritis With Ultrasonography and Evaluation of Muscle Architecture Change by Ultrasonography After Isokinetic Exercise Program (NCT05019820) | Sema Dağcı | 2021-08-18 |
| Postmarketing Multicenter Study of Intra-Articular DIART ONE / EASYGO ONE for Knee Osteoarthritis (NCT06927934) | Yuria-Pharm | 2021-08-14 |
| 3-year, Open-Label Study Evaluating Safety, Tolerability, and Efficacy of Lorecivivint in Knee Osteoarthritis (NCT04931667) | Biosplice Therapeutics, Inc. | 2021-07-15 |
| Exploratory Study on Safety of PEEK Knee Prosthesis (NCT04927104) | RenJi Hospital | 2021-06-25 |
| Irritation and Sensitization Study of HP-5000 Topical System (NCT04882319) | Noven Pharmaceuticals, Inc. | 2021-06-03 |
| LOW LOAD RESISTANCE BLOOD FLOW RESTRICTION TRAINING VERSUS NEUROMUSCULAR TRAINING IN KNEE OSTEOARTHRITIS (NCT04600661) | Mai Mohamed Abdelkader Abdallah | 2021-01-15 |
| Extended and Controlled Release Liposomal Formulated Dexamethasone for Chronic Knee OA Pain (NCT04123561) | Taiwan Liposome Company | 2019-11-26 |
| A Pragmatic Trial To Determine the Benefit of Exercise Incentives and Corticosteroid Injections in Osteoarthritis of the Knee (NCT03835910) | VA Office of Research and Development | 2019-07-08 |
| A Study to Examine the Efficacy and Safety of REGN5069 in Patients With Pain Due to Osteoarthritis of the Knee (NCT03956550) | Regeneron Pharmaceuticals | 2019-05-21 |
| A Phase 2, Open Label, Pharmacokinetic (PK) Study of TLC599 in Subjects With Osteoarthritis of the Knee (NCT03754049) | Taiwan Liposome Company | 2019-01-21 |
| A Study of the Efficacy and Safety of CF101 to Patients With Osteoarthritis of the Knee (NCT00837291) | Can-Fite BioPharma | 2018-11-01 |
| Clinical Study of Umbilical Cord Mesenchymal Stem Cells (UC-MSC) for Treatment of Knee Osteoarthritis (NCT03166865) | Liaocheng People's Hospital | 2018-10-01 |
| Cooled Radiofrequency vs. Hyaluronic Acid to Manage Knee Pain (NCT03381248) | Avanos Medical | 2017-12-07 |
| A 4-week Study to Evaluate the Efficacy and Safety of HP-5000 in Subjects With Knee Osteoarthritis (NCT03277066) | Noven Pharmaceuticals, Inc. | 2017-09-07 |
| 3D Printing Guides in Total Knee Arthroplasty (NCT04206202) | Southwest Hospital, China | 2017-05-01 |
| Polycan in Combination With Glucosamine for Treatment of Knee Osteoarthritis (NCT03717714) | Vietstar Biomedical Research | 2017-04-01 |
| Phase IIa, Randomized, Double Blinded, Placebo Controlled, Dose Finding Study for TLC599 in OA Patients (NCT03005873) | Taiwan Liposome Company | 2017-03-16 |
| Multicentre GMK UNI Anatomical Cementless Study - FR (NCT06715917) | Medacta International SA | 2017-03-06 |
| Study to Assess the Safety of Repeat Administration of FX006 Administered to Patients With Osteoarthritis of the Knee (NCT03046446) | Pacira Pharmaceuticals, Inc | 2017-02-20 |
| Genicular Radiofrequency Ablation for Unilateral Knee Arthroplasty Pain Management (NCT02925442) | Lyman Medical Research Foundation, Inc. | 2017-01-25 |
| Effects of Perioperative Intravenous Dexamethasone on the Severity of Persistent Postsurgical Pain After Total Knee Arthroplasty : A Prospective, Randomized, Double-blind, Placebo-controlled Trial (NCT02760459) | Chiang Mai University | 2016-10-01 |
| KineSpring® System Patient Preference Study (NCT02934672) | Moximed | 2016-06-01 |
| Study to Assess the Effects of FX006 on Blood Glucose in Patients With OA of the Knee and Type 2 Diabetes (NCT02762370) | Pacira Pharmaceuticals, Inc | 2016-04-01 |
| Evaluation of Amniotic Fluid Product in Knee Osteoarthritis (NCT02768155) | MiMedx Group, Inc. | 2016-04-01 |
| A Proof-of-Concept Study Assessing NEO6860 in Osteoarthritis Pain (NCT02712957) | Neomed Institute | 2016-03-01 |
| A Study to Assess the Analgesic Efficacy of ASP7962 in Patients With Pain Due to Osteoarthritis of the Knee (NCT02611466) | Astellas Pharma Europe B.V. | 2016-02-16 |
| A Study on the Efficacy of Glucosamine Sulfate Potassium Chloride/Standardized Ginkgo Biloba Leaf Extract in Adults With Osteoarthritis of the Knee. (NCT02604381) | KGK Science Inc. | 2015-11-01 |
| Study to Characterize the PK and Local Extent and Duration of Exposure From FX006 in Patients With OA of the Knee (NCT02637323) | Pacira Pharmaceuticals, Inc | 2015-11-01 |
| A Study to Evaluate the Efficacy & Safety of an Intra-Articular Ampion Injection for Pain of Osteoarthritis of the Knee (NCT02556710) | Ampio Pharmaceuticals. Inc. | 2015-09-01 |
| Outcomes of Injections in Patients Waiting for Total Knee Replacement (NCT03090698) | Universidade Federal Fluminense | 2015-09-01 |
| Single-Dose Administration Trial of TLC599 in Osteoarthritis of the Knee (NCT02803307) | Taiwan Liposome Company | 2015-06-01 |
| PRP Treatment of Osteoarthritic Knee With a New Autologous Blood Product (CytoRich) (NCT03543800) | Antnor | 2015-02-04 |
| Repeat Injection of Cingal® for Osteoarthritis of the Knee (NCT02381652) | Anika Therapeutics, Inc. | 2015-02-01 |
| A Prospective Radiostereometric Analysis (RSA) and Clinical Evaluation of the Triathlon Tritanium Total Knee Replacement (NCT02373761) | Scott Sporer | 2015-02-01 |
| An Extension Study of Duloxetine in Osteoarthritis and Knee Pain (Extension of F1J-JE-HMGX, NCT02248480) (NCT02335346) | Eli Lilly and Company | 2015-01-01 |
| Study of FX006 for the Treatment of Pain in Patients With Osteoarthritis of the Knee (NCT02357459) | Pacira Pharmaceuticals, Inc | 2015-01-01 |
| Nerve Ablation by Cooled Radiofrequency Compared to Corticosteroid Injection for Management of Knee Pain (NCT02343003) | Halyard Health | 2015-01-01 |
| Virtual Reality for Osteoarthritis Knee Pain Pilot (NCT01899508) | Duke University | 2015-01-01 |
| Knee Osteoarthritis Risk in Retired Professional Footballers (NCT02098044) | University of Nottingham | 2014-11-01 |
| A Multiple Injection Study Evaluating Safety and Efficacy of Ampion in Osteoarthritis (NCT02242435) | Ampio Pharmaceuticals. Inc. | 2014-09-01 |
| Clinical Study of Umbilical Cord Tissue Mesenchymal Stem Cells (UC-MSC) for Treatment of Osteoarthritis (NCT02237846) | Translational Biosciences | 2014-09-01 |
| A Study to Evaluate Safety of Three Intra-articular Injections of Ampion in the Knee of Adults With Osteoarthritis Pain (NCT02184156) | Ampio Pharmaceuticals. Inc. | 2014-06-01 |
| A Study to Evaluate the Safety and Efficacy of Topically Applied TV-45070 (Ointment) in Participants With Primary Osteoarthritis (OA) Affecting a Single Knee (NCT02068599) | Teva Branded Pharmaceutical Products R&D, Inc. | 2014-04-14 |
| Effect of Phototherapy Incorporated Into an Exercise Program on Osteoarthritis of the Knee (NCT02102347) | University of Nove de Julho | 2014-04-01 |
| Study of FX006 vs Normal Saline in Patients With Osteoarthritis of the Knee (NCT02116972) | Pacira Pharmaceuticals, Inc | 2014-04-01 |
| ADSC Injections for Pain Management of Osteoarthritis in the Human Knee Joint (NCT02357485) | Fodor, Peter B, M.D. | 2014-03-01 |
| Cardiovascular And Metabolic Risk After Arthroplasty (NCT06211465) | University of Tartu | 2014-03-01 |
| To Compare the Efficacy and Safety of LAYLA in Osteoarthritis Patients of the Knee (NCT02049606) | PMG Pharm Co., Ltd | 2014-02-24 |
| A Study to Evaluate the Efficacy and Safety of X0002 Spray in Subjects With Osteoarthritis (NCT02067611) | Lina Xu | 2014-02-01 |
| Prospective Functional Outcome Study of the Knee (NCT02079493) | Tufts Medical Center | 2014-01-01 |
| A Randomized, Controlled Study to Evaluate Efficacy and Safety of Intra-articular Ampion for Osteoarthritis Pain in Knee (NCT02024529) | Ampio Pharmaceuticals. Inc. | 2014-01-01 |
| Cabbage Leaf Wraps in Osteoarthritis of the Knee (NCT02027792) | Universität Duisburg-Essen | 2014-01-01 |
| Apitox, Honeybee Toxin for Pain and Inflammation of Osteoarthritis (NCT01112722) | Apimeds, Inc. | 2013-12-01 |
| Safety and Feasibility Study of Mesenchymal Trophic Factor (MTF) for Treatment of Osteoarthritis (NCT02003131) | Translational Biosciences | 2013-12-01 |
| Effectiveness of Osteopathy in the Preoperative Treatment of Postoperative Pain in Patients Undergoing Total Knee Replacement (NCT01989117) | Hospital Ambroise Paré Paris | 2013-11-01 |
| Study to Characterize the Local Duration of Exposure From FX006 in Patients With Osteoarthritis of the Knee (NCT02003365) | Pacira Pharmaceuticals, Inc | 2013-11-01 |
| Targeted Rehabilitation to Improve Outcome After Knee Replacement- A Physiotherapy Study (NCT01849445) | University of Edinburgh | 2013-09-01 |
| Nerve Burial for Preventing Neuralgia After Total Knee Arthroplasty (NCT02885467) | Medstar Health Research Institute | 2013-08-01 |
| Triathlon PKR Study in Japan (NCT02552095) | Stryker Japan K.K. | 2013-06-01 |
| Effect of Bioskin Ten-7 vs. Standard Treatment on Patient Reported Outcomes and Cytokine. (NCT02295020) | Cropper Medical | 2013-05-01 |
| EMBARK Follow-up Project (NCT02195674) | Duke University | 2013-04-01 |
| Sleep, Pain and Inflammatory Processes in Older Adults With Osteoarthritis (NCT01683799) | University of Rochester | 2013-02-01 |
| A Prospective, Multicenter Study to Evaluate the ConforMIS iTotal® (CR) Knee Replacement System (NCT01820650) | Restor3D | 2013-02-01 |
| Phase 2 Efficacy Trial of OLT1177 Gel in Subjects With Moderate to Severe Pain Associated With OA of the Knee (NCT01768975) | Olatec Therapeutics, Inc. | 2013-01-01 |
| Efficacy and Safety of Imotun Capsule in Osteoarthritis of the Knee (NCT01756937) | Chong Kun Dang Pharmaceutical | 2013-01-01 |
| The Study to Evaluate Efficacy and Safety of Imotun Capsule in Osteoarthritis of the Knee (NCT01743287) | Chong Kun Dang Pharmaceutical | 2012-12-01 |
| Flex Intramedullary Rod Study (NCT02543489) | Stryker Japan K.K. | 2012-12-01 |
| To Compare the Efficacy and Safety of LAYLA in Osteoarthritis Patients (NCT01768468) | PMG Pharm Co., Ltd | 2012-10-01 |
| A Prospective Study Evaluating the Treatment of Knee Osteoarthritis With the Cryo-Touch III Device (NCT01704157) | Pacira Pharmaceuticals, Inc | 2012-09-01 |
| Pharmacokinetic and Pharmacodynamic Study of FX006 in Patients With Osteoarthritis of the Knee (NCT01487200) | Pacira Pharmaceuticals, Inc | 2012-07-01 |
| A Phase 2 Study To Assess The Efficacy, Tolerability, And Safety OF NKTR-181 In Subjects With Chronic OA Knee Pain (NCT01619839) | Nektar Therapeutics | 2012-06-01 |
| Hydroxychloroquine/Atorvastatin in the Treatment of Osteoarthritis (OA) of the Knee (NCT01645176) | Stanford University | 2012-05-01 |
| Safety, Tolerability, and Efficacy of IA Verapamil in the Treatment of Joint Pain in Subjects With Osteoarthritis of the Knee (NCT01645709) | Calosyn Pharma, Inc. | 2012-04-01 |
| Assays for and Reversal of New Anticoagulants (NCT01795781) | R.P.Herrmann | 2012-04-01 |
| A Four-Week Multicenter Study Evaluating the Safety and Efficacy of Gefapixant (AF-219/MK-7264) in Subjects With Osteoarthritis of the Knee (NCT01554579) | Afferent Pharmaceuticals, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 2012-03-29 |
| Safety and Efficacy of Etoricoxib 30 mg Versus Celecoxib 200 mg in Korean Participants With Osteoarthritis (NCT01554163) | Organon and Co | 2012-03-01 |
| Serum and Synovium Protease Inhibitor Levels in Primary and Secondary Osteoarthritic Joints (NCT01613833) | Scuderi, Gaetano J., M.D. | 2012-03-01 |
| Trial to See if Topical Pennsaid for Knee Pain Affects Coagulation Values in Patients Who Are Also Taking Anticoagulants (NCT01511939) | Nathan Wei, MD, FACP, FACR: | 2012-02-01 |
| Structured Non-operative Treatment of Knee Osteoarthritis (NCT01535001) | Northern Orthopaedic Division, Denmark | 2012-02-01 |
| Clinical and Stereoradiological Comparison of the Results After Primary Cemented Total Knee Arthroplasty Inserted With or Without the Use of a Tourniquet (NCT01488175) | Hvidovre University Hospital | 2012-01-01 |
| Efficacy and Safety of LBSA0103 Versus Hyruan Plus Injection in Patients With Knee Osteoarthritis (NCT01510535) | LG Life Sciences | 2011-12-01 |
| Investigation of Specific Protein/Markers in Patients With Osteoarthritis of the Knee Having a Total Knee Replacement (NCT01611441) | AstraZeneca | 2011-12-01 |
| Effect Of Meloxicam Versus Placebo In Mainland Chinese Patients With Osteoarthritis Of The Knee (NCT01430559) | Pfizer | 2011-10-24 |
| A Study of ABT-652 in Combination With a Nonsteroidal Anti-Inflammatory Drug (NSAID) in Adults With Osteoarthritis Pain of the Knee (NCT01444365) | AbbVie (prior sponsor, Abbott) | 2011-10-01 |
| Structured Treatment of Osteoarthritis of the Knee With or Without Total Knee Replacement (NCT01410409) | Northern Orthopaedic Division, Denmark | 2011-09-01 |
| Cross-over Study of the Efficacy and Safety of SierraSil Joint Formula 14 in Osteoarthritis of the Knee (NCT02156440) | KGK Science Inc. | 2011-09-01 |
| Platelet Rich Plasma (PRP) as a Treatment for Knee Osteoarthritis PRP as a Treatment for Knee Osteoarthritis (NCT01270412) | Meir Medical Center | 2011-09-01 |
| Efficacy of Spearmint Tea in Relieving Osteoarthritis of the Knee (NCT01380015) | University of Guelph | 2011-07-01 |
| Can Computer-based Telephone Counseling Improve Long-term Adherence to Strength Training in Elders With Knee OA? (NCT01394874) | Boston University Charles River Campus | 2011-07-01 |
| A Study of ARRY-371797 in Patients With Osteoarthritis of the Knee (NCT01366014) | Pfizer | 2011-06-01 |
| Assessment of GRT6005 in Painful Osteoarthritis of the Knee (NCT01357837) | Tris Pharma, Inc. | 2011-05-01 |
| The Use of Fibrin Sealant to Reduce Bleeding After Total Knee Replacement (NCT01816282) | University of Milan | 2011-03-01 |
| Axial Alignment in Patients Operated Using the Visionaire Patient Matched Cutting Blocks (NCT01224522) | Smith & Nephew Orthopaedics AG | 2011-03-01 |
| Measures of Pain Relevant to Knee Osteoarthritis (NCT01310257) | University of Nottingham | 2010-12-01 |
| Efficacy and Safety of 3 Different Dosage Regimens of Hyaluronic Acid in Patients With Knee Osteoarthritis (OA) (NCT01290497) | Tedec-Meiji Farma, S.A. | 2010-11-01 |
| Exploratory Study of PENNSAID Gel to Treat Symptoms of Knee Osteoarthritis (NCT01119898) | Mallinckrodt | 2010-08-02 |