Atlas Trials

Ornithine Transcarbamylase Deficiency

19 clinical trials · Condition

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RecordFirmDate
Hepatic Histopathology in Urea Cycle Disorders (NCT04908319)Baylor College of Medicine2022-02-24
Liver Disease in Urea Cycle Disorders (NCT04612764)Baylor College of Medicine2021-11-04
Adeno-Associated Virus (AAV) Antibody Study in Subjects OTC Deficiency, GSDIa, and Wilson Disease (NCT04909346)Ultragenyx Pharmaceutical Inc2021-06-23
Phase 1b Study to Assess Safety, Tolerability, and Pharmacokinetics of ARCT-810 in Stable Adult Subjects With Ornithine Transcarbamylase Deficiency (NCT04442347)Arcturus Therapeutics, Inc.2020-11-03
Study to Characterize Rate of Ureagenesis in Patients With Ornithine Transcarbamylase (OTC) Deficiency (NCT04717453)Ultragenyx Pharmaceutical Inc2020-10-06
Safety, Tolerability and Pharmacokinetics of ARCT-810 in Healthy Adult Subjects (NCT04416126)Arcturus Therapeutics, Inc.2020-06-01
Safety, Tolerability and PK/PD Evaluation of Intravenous Administration of MRT5201 in Patients With OTC Deficiency (NCT03767270)Translate Bio, Inc.2019-12-01
A Study to Assess Plasma Ammonia Time-Normalized Area Under the Curve and Rate of Ureagenesis in Healthy Adult Subjects (NCT04269122)Ultragenyx Pharmaceutical Inc2019-08-02
Early Check: Expanded Screening in Newborns (NCT03655223)RTI International2018-10-15
Investigation of Brain Nitrogen in Partial Ornithine Transcarbamylase Deficiency (OTCD) Using 1 H MRS, DTI, and fMRI (NCT01569568)Andrea Gropman2010-09-01
Human Heterologous Liver Cells for Infusion in Children With Urea Cycle Disorders (NCT00718627)Cytonet GmbH & Co. KG2008-07-01
Neurologic Injuries in Adults With Urea Cycle Disorders (NCT00472732)Andrea Gropman2007-03-01

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