| The Gut Microbiome and Immune Checkpoint Inhibitor Therapy in Solid Tumors (NCT05037825) | VastBiome | 2021-11-22 |
| NT-I7 in Combination With Atezolizumab in Previously Untreated, PD-L1-expressing, Locally Advanced or Metastatic NSCLC (NCT04984811) | NeoImmuneTech | 2021-11-15 |
| Light Dosimetry for Photodynamic Therapy With Porfimer Sodium in Treating Participants With Malignant Mesothelioma or Non-Small Cell Lung Cancer With Pleural Disease Undergoing Surgery (NCT03678350) | Roswell Park Cancer Institute | 2021-09-17 |
| A Study of AZD2936 Anti-TIGIT/Anti-PD-1 Bispecific Antibody in Participants With Advanced or Metastatic NSCLC (NCT04995523) | AstraZeneca | 2021-09-14 |
| Efficacy and Safety of Almonertinib Combined With or Without Chemotherapy as an Adjuvant Treatment for Stage II-IIIA Non-small Cell Lung Carcinoma Following Complete Tumour Resection (NCT04762459) | Chinese Academy of Medical Sciences | 2021-08-01 |
| Nous-PEV: a Novel Immunotherapy for Lung Cancer and Melanoma (NCT04990479) | Nouscom SRL | 2021-06-11 |
| To Assess the Efficacy and Safety of Furmonertinib Versus Placebo, in Patients With Epidermal Growth Factor Receptor Mutation Positive Stage II-IIIA Non-small Cell Lung Carcinoma, Following Complete Tumour Resection With or Without Adjuvant Chemotherapy (NCT04853342) | Allist Pharmaceuticals, Inc. | 2021-06-07 |
| Coformulation of Pembrolizumab/Vibostolimab (MK-7684A) Versus Pembrolizumab (MK-3475) Monotherapy for Programmed Cell Death 1 Ligand 1 (PD-L1) Positive Metastatic Non-Small Cell Lung Cancer (MK-7684A-003, KEYVIBE-003) (NCT04738487) | Merck Sharp & Dohme LLC | 2021-04-07 |
| An Investigational Immuno-therapy Study of Nivolumab Given After Surgery in Non-Small Cell Lung Cancer (NSCLC) Participants With Minimal Residual Disease (NCT03770299) | Bristol-Myers Squibb | 2021-01-15 |
| The Evaluation of PC14586 in Patients With Advanced Solid Tumors Harboring a TP53 Y220C Mutation (PYNNACLE) (NCT04585750) | PMV Pharmaceuticals, Inc | 2020-10-29 |
| NEUWAVE Flexible Probe Study #2 (NCT03713099) | Ethicon, Inc. | 2020-07-31 |
| A Study to Learn About Lorlatinib in Patients With Non-Small Cell Lung Cancer Which Could Not Be Controlled (NCT06282991) | Pfizer | 2020-07-22 |
| Anaplastic Lymphoma Kinase (ALK)-Positive Non-small Cell Lung Cancer (NSCLC) Post-alectinib Treatment Patterns (NCT04351334) | Pfizer | 2020-03-01 |
| Endobronchial Ultrasound Guided Interstitial Photodynamic Therapy in Treating Patients With Locally Advanced Lung Cancer (NCT03735095) | Roswell Park Cancer Institute | 2020-02-12 |
| DS8201a and Pembrolizumab in Participants With Locally Advanced/Metastatic Breast or Non-Small Cell Lung Cancer (NCT04042701) | Daiichi Sankyo | 2020-02-10 |
| Osimertinib Resistance in Patients With Non-small-cell Lung Carcinoma That Have Progressed. (NCT04737382) | The Netherlands Cancer Institute | 2019-08-22 |
| A Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid Tumors (NCT03849469) | Xencor, Inc. | 2019-05-29 |
| A Study of XmAb®23104 in Subjects With Selected Advanced Solid Tumors (DUET-3) (NCT03752398) | Xencor, Inc. | 2019-05-01 |
| A Phase 2 Study Adding Ascorbate to Chemotherapy and Radiation Therapy for NSCLC (NCT02905591) | Joseph J. Cullen, MD, FACS | 2018-11-16 |
| Online Psychosocial Intervention in Improving Social Well-Being and Support in Women With Stage I-IV Non-small Cell Lung Cancer Undergoing Treatment (NCT03731585) | M.D. Anderson Cancer Center | 2018-11-15 |
| Abexinostat in Combination With Pembrolizumab in Patients With Advanced Solid Tumor Malignancies (NCT03590054) | Rahul Aggarwal | 2018-08-20 |
| A Study of XmAb®20717 in Subjects With Selected Advanced Solid Tumors (NCT03517488) | Xencor, Inc. | 2018-07-10 |
| Bronchoscopy With Bronchoalveolar Lavage in Identifying Biomarkers of Response to Immune Checkpoint Inhibitors in Patients With Non-small Cell or Small Cell Lung Cancer (NCT02937402) | Vanderbilt-Ingram Cancer Center | 2018-04-05 |
| Social Media Listening in Improving Clinical Trial Recruitment in Patients With Cancer (NCT03408561) | University of Southern California | 2017-11-08 |
| Afatinib and Necitumumab in Patients With EGFR Mutation Positive Advanced or Metastatic Non-small Cell Lung Cancer (NCT03054038) | Vanderbilt-Ingram Cancer Center | 2017-07-20 |
| Patient Navigation for Lung Cancer Screening in an Urban Safety-Net System (NCT02758054) | University of Texas Southwestern Medical Center | 2017-06-16 |
| Study of REGN 2810 Compared to Platinum-Based Chemotherapies in Participants With Metastatic Non-Small Cell Lung Cancer (NSCLC) (NCT03088540) | Regeneron Pharmaceuticals | 2017-05-29 |
| A Study of Nivolumab + Chemotherapy or Nivolumab + Ipilimumab Versus Chemotherapy in Non-Small Cell Lung Cancer (NSCLC) Participants With Epidermal Growth Factor Receptor (EGFR) Mutation Who Failed 1L or 2L EGFR Tyrosine Kinase Inhibitor (TKI) Therapy (NCT02864251) | Bristol-Myers Squibb | 2017-03-17 |
| Anti PD-1 Neo-adjuvant Treatment for NSCLC (NCT02938624) | Jair Bar, M.D., Ph.D. | 2017-01-07 |
| Neoadjuvant Pembrolizumab (NCT02818920) | Neal Ready MD PhD | 2017-01-01 |
| Efficacy-Safety-Immunogenicity Study of CBT124&EU-sourced Avastin® in Stage 4 NSCLC (NCT02879097) | Cipla BioTec Pvt. Ltd. | 2016-12-01 |
| Trial of Dose Escalated BGB324 in Previously Treated Non-small Cell Lung Cancer. (NCT02922777) | University of Texas Southwestern Medical Center | 2016-11-01 |
| Study Assessing Activity of Molecularly Matched Targeted Therapies in Select Tumor Types Based on Genomic Alterations (NCT02795156) | SCRI Development Innovations, LLC | 2016-09-28 |
| Vaccine Therapy and Pembrolizumab in Treating Patients With Solid Tumors That Have Failed Prior Therapy (NCT02432963) | City of Hope Medical Center | 2016-06-14 |
| N2 Lung Cancer Project: Neoadjuvant Treatment Followed Surgery Versus Chemoradiation (NCT02966769) | Grupo de Investigación Clínica en Oncología Radioterapia | 2016-06-01 |
| Evaluation of Tumor and Blood Immune Biomarkers in Resected Non-small Cell Lung Cancer (NCT02848872) | Duke University | 2016-05-01 |
| A Phase I Clinical Study With Investigational Compound LTT462 in Adult Patients With Specific Advanced Cancers. (NCT02711345) | Novartis Pharmaceuticals | 2016-04-15 |
| Study of Pemetrexed+Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Participants With First Line Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-3475-189/KEYNOTE-189)-Japan Extension Study (NCT03950674) | Merck Sharp & Dohme LLC | 2016-02-22 |
| CT Perfusion Imaging in Predicting Treatment Response in Patients With Non-small Cell Lung Cancer or Lung Metastases Treated With Stereotactic Ablative Radiation Therapy (NCT02693080) | Stanford University | 2016-01-19 |
| Study of Pemetrexed+Platinum Chemotherapy With or Without Pembrolizumab (MK-3475) in Participants With First Line Metastatic Nonsquamous Non-small Cell Lung Cancer (MK-3475-189/KEYNOTE-189) (NCT02578680) | Merck Sharp & Dohme LLC | 2016-01-15 |
| Optical Biopsy for Thoracic Lymph Nodes. (NCT02689050) | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 2016-01-13 |
| Hypermetabolism in the Elderly Lung Cancer Patient (NCT03141957) | University of Paris 5 - Rene Descartes | 2016-01-01 |
| The Value Of Circulating Tumor Cells In Patient With NSCLC In Postoperative Recurrence Monitoring (NCT02647164) | GenoSaber | 2016-01-01 |
| Talazoparib in Combination With Gemcitabine and Cisplatin in Patients With Advanced Solid Tumors (NCT02537561) | Washington University School of Medicine | 2015-12-01 |
| Evaluation of FLT-PET and DWI-MRI in Patients With NSCLC Treated With a Platinum-based Doublet as Preoperative Chemo (NCT02273271) | European Organisation for Research and Treatment of Cancer - EORTC | 2015-10-01 |
| IMRT Combined With Erlotinib for EGFR Wild Type Non-small Cell Lung Cancer With 4-10 Brain Metastases (NCT02556593) | Sun Yat-sen University | 2015-09-01 |
| Phase I Trial Of IMRT Using A Contralateral Esophagus Sparing Technique (CEST) In Locally Advanced Lung Cancer (NCT02394548) | Massachusetts General Hospital | 2015-06-01 |
| Anticancer Activity of Nicotinamide on Lung Cancer (NCT02416739) | Il Yeong Park, Ph.D. | 2015-03-01 |
| Study of the Efficacy of SBRT on Unresectable Peripheral Primary Tumor (NCT02400424) | Centre Leon Berard | 2015-02-01 |
| Combination of gp96-Ig Vaccine, Theophylline and Oxygen for the Treatment of Patients With Advanced, Relapsed or Metastatic Non-Small Cell Lung Cancer (NCT01799161) | Eckhard Podack | 2014-12-01 |
| Study of Pembrolizumab (MK-3475) Compared to Platinum-Based Chemotherapies in Participants With Metastatic Non-Small Cell Lung Cancer (MK-3475-024/KEYNOTE-024) (NCT02142738) | Merck Sharp & Dohme LLC | 2014-08-25 |
| Chemotherapy and Radiation Therapy With or Without Metformin Hydrochloride in Treating Patients With Stage III Non-small Cell Lung Cancer (NCT02186847) | NRG Oncology | 2014-08-01 |
| Use of [18]F-FDG on PET/CT as an Alternative Non-invasive Method for Staging of Lung Cancer (NCT02664792) | Latin American Cooperative Oncology Group | 2014-08-01 |
| Phase I of Vorinostat-Iressa Combined Therapy on Resistance by BIM Polymorphysim in EGFR Mutant Lung Cancer (NCT02151721) | Kanazawa University | 2014-06-01 |
| Doxepin Hydrochloride in Treating Esophageal Pain in Patients With Thoracic Cancer Receiving Radiation Therapy to the Thorax With or Without Chemotherapy (NCT02062632) | Mayo Clinic | 2014-04-14 |
| A Study of Pembrolizumab (MK-3475) in Combination With Chemotherapy or Immunotherapy in Participants With Non-small Cell Lung Cancer (MK-3475-021/KEYNOTE-021) (NCT02039674) | Merck Sharp & Dohme LLC | 2014-02-21 |
| Phase 3 Study of Bavituximab Plus Docetaxel Versus Docetaxel Alone in Patients With Late-stage Non-squamous Non-small-cell Lung Cancer (NCT01999673) | Peregrine Pharmaceuticals | 2013-12-01 |
| A Phase 1 Study of Pegilodecakin (LY3500518) in Participants With Advanced Solid Tumors (NCT02009449) | Eli Lilly and Company | 2013-11-15 |
| Folic Acid-Tubulysin Conjugate EC1456 In Patients With Advanced Solid Tumors (NCT01999738) | Endocyte | 2013-10-01 |
| A Study of Alectinib (RO5424802) in Participants With Non-Small Cell Lung Cancer Who Have Anaplastic Lymphoma Kinase (ALK) Mutation and Failed Crizotinib Treatment (NCT01801111) | Hoffmann-La Roche | 2013-06-20 |
| Trial of RNActive®-Derived Cancer Vaccine and Local Radiation in in Stage IV Non Small Cell Lung Cancer (NSCLC) (NCT01915524) | CureVac | 2013-04-01 |
| Clinical Trial: Effectiveness and Efficiency of Physical Exercise in Cancer Patients (NCT01786122) | Basque Health Service | 2013-04-01 |
| Risk-adapted Stereotactic Body Radiotherapy for Early Non-Small Cell Lung Cancer Using the VERO Stereotactic Body Radio Therapy System (NCT02224547) | Universitair Ziekenhuis Brussel | 2013-01-01 |
| Genotype-Driven Treatment of Advanced Non-small Cell Lung Cancer Based on mRNA Expression of ERCC1 & RRM1 as First-line Chemotherapy (NCT01648517) | Yonsei University | 2012-07-27 |
| Phase IIB/III Of TG4010 Immunotherapy In Patients With Stage IV Non-Small Cell Lung Cancer (NCT01383148) | Transgene | 2012-04-01 |
| Assessment of 4D 18F-FDG PET-CT in Radiotherapy for Non Small Cell Lung Cancers (NCT01421953) | University Hospital, Bordeaux | 2011-08-01 |
| A Study in Non-Small Cell Lung Cancer (NCT01232452) | Eli Lilly and Company | 2011-04-01 |
| A Study of DS-2248 in Participants With Advanced Solid Tumors (NCT01288430) | Daiichi Sankyo | 2011-03-29 |
| Frequency of EGFR Mutations in Latinos/Hispanics With Non-Small Cell Lung Cancer (NCT01255150) | National Cancer Institute (NCI) | 2010-12-01 |
| Observing Patients With Palliative Asymptomatic Centrally Located Advanced Non-small Cell Lung Carcinoma (NSCLC) (NCT01279408) | University Health Network, Toronto | 2010-11-01 |
| Randomized Phase II Study of AZD6244 (Mitogen-activated Protein Kinase Inhibitor) MEK-Inhibitor With Erlotinib in KRAS Wild Type Advanced Non-Small Cell Lung Cancer (NSCLC) and a Randomized Phase II Study of AZD6244 With Erlotinib in Mutant KRAS Adva... (NCT01229150) | National Cancer Institute (NCI) | 2010-10-26 |
| Stereotactic Body Radiation Therapy (SBRT) in Metastatic Non-small Cell Lung Cancer (NCT01185639) | Wake Forest University Health Sciences | 2010-08-01 |
| Trial of BMS-690514 in Non-Small Cell Lung Cancer Subjects Who Have Been Treated With Gefitinib or Erlotinib and Are Genotypically EGFR Mutation Positive or Who Have Had a Prior Response (NCT01167244) | Bristol-Myers Squibb | 2010-08-01 |
| Safety Study of Cetuximab in Combination With Cisplatin and Vinorelbine to Treat Advanced Non-small Cell Lung Cancer (NCT01109524) | Eli Lilly and Company | 2010-07-01 |
| Study of Vorinostat and Gefitinib in Relapsed/ or Refractory Patients With Advanced Non-small Cell Carcinoma (NSCLC) (NCT01027676) | National Cancer Center, Korea | 2010-06-01 |
| Safety and Efficacy of Belinostat When Used With Standard of Care Chemotherapy for Untreated Non-small Cell Lung Cancer (NCT01090830) | Holy Cross Hospital, Florida | 2010-04-01 |
| Molecular Imaging With Erlotinib and Bevacizumab (NCT01047059) | University of Cologne | 2010-01-01 |
| Feasibility of Cetuximab Associated With Concomitant Radio-Chemotherapy in Patients With Locally Advanced Non Small Cell Lung Cancer (NCT00985855) | Institut de Cancérologie de la Loire | 2009-09-01 |
| Residual Hypermethylation in Early Stage Non-Small Cell Lung Cancer (NSCLC) As Part of Adjuvant Therapy and Preventive Strategy (NCT01209520) | University of Miami | 2009-07-01 |
| Biological Factors Predicting Response to Chemotherapy in Advanced Non Small Cell Lung Cancer (NCT00864266) | European Lung Cancer Working Party | 2009-03-01 |
| Non-Interventional Study With Vinorelbine ORAL in Advanced Non-Small Cell Lung Carcinoma(NSCLC) and Metastatic Breast Cancer (MBC) (NCT00890903) | Pierre Fabre Pharma GmbH | 2009-03-01 |
| A Study of V934/V935 Vaccine in Cancer Participants With Selected Solid Tumors (V934-002) (NCT00753415) | Merck Sharp & Dohme LLC | 2008-08-01 |
| Prognostic Role of Primary Non Small Cell Lung Carcinoma Standardized F18-FDG Uptake Values (SUV and TLG) Measured With F18-fluorodeoxyglucose Positron Emission Tomography (F18-FDG-PET): a Non Interventional Study. (NCT00759382) | European Lung Cancer Working Party | 2008-07-01 |
| Alimta® Versus Its Combination With Carboplatin in Advanced Non-small-cell Lung Cancer in Patients Performance Status 2 (NCT01836575) | Instituto Nacional de Cancer, Brazil | 2008-04-01 |
| A Study to Assess the Safety and Preliminary Efficacy of PT-523 in Patients With Advanced Non-Small Cell Lung Cancer (NSCLC) (NCT00112060) | Spectrum Pharmaceuticals, Inc | 2008-04-01 |
| A Study Of AG-013736 (Axitinib) Or Bevacizumab (Avastin) In Combination With Paclitaxel And Carboplatin In Patients With Advanced Lung Cancer. (NCT00600821) | Pfizer | 2008-04-01 |
| Phase I Study of Vorinostat and Sorafenib in Advanced Cancer (NCT00635791) | University of Colorado, Denver | 2008-03-01 |
| Study to Evaluate Erlotinib With or Without SNDX-275 (Entinostat) in the Treatment of Patients With Advanced NSCLC (NCT00602030) | Syndax Pharmaceuticals | 2008-01-08 |
| Albumin-bound Paclitaxel (ABI-007) for Patients With Advanced Non-Small Cell Lung Cancer (NCT00540514) | Celgene | 2007-11-01 |
| Effect of All-trans Retinoic Acid With Chemotherapy Based in Paclitaxel and Cisplatin as First Line Treatment of Patients With Advanced Non-small Cell Lung Cancer (NCT01048645) | National Institute of Cancerología | 2007-09-01 |
| Study Evaluating the Addition of Fulvestrant to Erlotinib in Stage IIIB/IV Non-Small Cell Lung Cancer (NCT00592007) | Lyudmila Bazhenova, M.D. | 2007-09-01 |
| Study to Evaluate Combination Treatment of MGCD0103 and Docetaxel (Taxotere®) for Subjects With Advanced Cancer Tumors (NCT00511576) | Mirati Therapeutics Inc. | 2007-08-01 |
| Protocol for Primary Fractionated Stereotactic Body Radiation Therapy for Stage T1 - T3N0 Non Small Cell Lung Carcinoma. (NCT00727350) | Universitair Ziekenhuis Brussel | 2007-03-01 |
| Phase I Dasatinib/Erlotinib in Recurrent Non-small Cell Lung Cancer (NSCLC) (NCT00444015) | H. Lee Moffitt Cancer Center and Research Institute | 2007-03-01 |
| SELINE: Second-Line Iressa Phase IV Study in NSCLC Patients (NCT00608868) | AstraZeneca | 2007-01-01 |
| Lobectomy and Mediastinal Radiochemotherapy in Unresectable Stage III Non-Small Cell Lung Cancer Responding to Induction Chemotherapy (NCT00661011) | European Lung Cancer Working Party | 2007-01-01 |
| Randomised Study of Concomitant Radiochemotherapy in Non-small Cell Lung Cancer (NCT00633568) | European Lung Cancer Working Party | 2007-01-01 |
| LUCY: A Study for the Treatment of Non-Small Cell Lung Cancer (NSCLC) in Patients Previously Treated With Chemotherapy (NCT00328588) | Astellas Pharma Inc | 2006-12-01 |
| ZD6474 (ZACTIMA™) Phase III Study in EGFR Failures (NCT00404924) | Genzyme, a Sanofi Company | 2006-11-01 |
| Concurrent Helical Tomotherapy With Chemotherapy in Unresectable Stage III Non-Small Cell Lung Cancer (NSCLC) (NCT00379717) | Universitair Ziekenhuis Brussel | 2006-11-01 |