| Safety and Efficacy of the HighLife Transcatherter Mitral Valve Replacement System in Patients With Moderate-severe or Severe Mitral Regurgitation in China (NCT05610566) | Peijia Medical Technology (Suzhou) Co., Ltd. | 2022-07-06 |
| The Multicenter Clinical Trial of a Novel TEER Decive (V-CLASP Trial) (NCT05391802) | Shanghai Zhongshan Hospital | 2022-06-30 |
| Haemodynamics of Mitral Regurgitation Reduction (NCT05403840) | Guy's and St Thomas' NHS Foundation Trust | 2022-06-06 |
| Transcatheter Mitral Valve Repair for Inotrope Dependent Cardiogenic Shock (NCT05298124) | Ottawa Heart Institute Research Corporation | 2022-05-26 |
| Comparison of Erector Spinae Block and Pecto-Intercostal Facial Block For Enhanced Recovery in Adult Cardiac Surgery (NCT05475561) | Alexandria University | 2022-05-25 |
| Cephea Early Feasibility Study (NCT05061004) | Abbott Medical Devices | 2022-04-28 |
| Optimal PeriproCeduraL AnticOagulation in Structural Transseptal Interventions (NCT05305612) | National Institute of Cardiology, Warsaw, Poland | 2022-03-13 |
| Outcomes of Patients tReated wIth Mitral Transcatheter Edge-to-edge Repair for Primary Mitral Regurgitation Registry (NCT05332782) | Universitätsklinikum Hamburg-Eppendorf | 2022-03-01 |
| The Role of Left Atrial Fibrosis in Mitral Valve Repair Surgery (ALIVE Trial) (NCT05345730) | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 2022-02-02 |
| Structural Mitral Valve Project (NCT05678868) | Queen's University | 2022-02-01 |
| MitraClip China PMS (NCT04259411) | Abbott Medical Devices | 2021-12-06 |
| Virtual Reality Reduces Pre-Procedural Anxiety in TEER Patients, But Timing Seems Crucial (NCT07263659) | Abby Geerlings | 2021-10-01 |
| Left Chamber Function in Mitral Regurgitation and Predicting Outcome After Replacement and Targeting for Early Surgery (NCT03870516) | Assiut University | 2021-09-20 |
| A Study to Evaluate a Computerized Stethoscope Called ©Voqx to Diagnose Heart Disease (NCT04960280) | Mayo Clinic | 2021-09-03 |
| Carillon Mitral Contour System for Treatment of Exercise Induced Functional Mitral Regurgitation (NCT05040451) | Cardiac Dimensions Pty Ltd | 2021-09-01 |
| Mi-STITCH™ and Mi-KNOT™ Device Technologies - Improvement of Mitral Valve Repair (NCT05034471) | Medical University of Vienna | 2021-08-05 |
| Change in LVEF Following Transcatheter Mitral Edge-To-Edge Repair (NCT05311163) | Rabin Medical Center | 2021-08-01 |
| EFS of the CardioMech MVRS (NCT04820764) | CardioMech AS | 2021-07-27 |
| Edge-To-Edge Technique Used as a Bailout in Case of Sub-Optimal Mitral Repair: Very Long-Term Results (NCT05733988) | Michele De Bonis | 2021-07-10 |
| HighFLO Study - HighLife Trans-septal Mitral Valve Replacement (TSMVR) Feasibility Study of the Open Cell CLARITY Valve (NCT04888247) | HighLife SAS | 2021-07-01 |
| Acquisition of Objective Data During Transapical Neochordae Implantation (NCT04709042) | Hospices Civils de Lyon | 2021-05-01 |
| Mitral Regurgitation Treatment in Advanced Heart Failure (NCT05292716) | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | 2021-04-21 |
| Tendyne European Experience Registry (NCT04898335) | LMU Klinikum | 2021-04-15 |
| Erector Spinae Plane Block for Minimally Invasive Mitral Valve Surgery (NCT04770961) | University of California, San Francisco | 2021-04-01 |
| SQ-Kyrin TMVr FIM Study (NCT05040074) | Shanghai Shenqi Medical Technology Co., Ltd | 2021-04-01 |
| LOng-Term Fate of Moderate Aortic Regurgitation Left Untreated at the Time of Mitral Valve Surgery (NCT05774795) | Michele De Bonis | 2021-03-24 |
| Coronary Physiology Peri-Transcatheter Left-sided Valvular Interventions (NCT05374733) | Erasmus Medical Center | 2021-03-22 |
| Implantation of a Permanent Interatrial Shunt to Reduce Left Atrial Filling Pressures Following MitraClip (NCT04729933) | samir kapadia | 2021-03-11 |
| The MITRAL II Pivotal Trial (Mitral Implantation of TRAnscatheter vaLves). (NCT04408430) | Mayra Guerrero | 2021-03-08 |
| Annuloplasty Rings and Band Post-Market Clinical Follow-Up Study (NCT04761120) | Abbott Medical Devices | 2021-02-01 |
| In Search of Best Practices for Patients With Heart Failure and Secondary Mitral Regurgitation: An Evaluation of the Inova Heart Failure Treatment Algorithm (NCT06675448) | Inova Health Care Services | 2021-01-28 |
| Evaluating Infrasonic Hemodynography (NCT04636892) | Scripps Health | 2021-01-04 |
| Beating Heart Mitral Valve Repair With the HARPOON™ System (NCT04375332) | Edwards Lifesciences | 2020-12-16 |
| Use of Phenylephrine for Assessment of Mitral Regurgitation Severity (NCT04500899) | Montefiore Medical Center | 2020-12-01 |
| Is Mitral Annuloplasty an Effective Treatment for Severe Atrial Functional MR? (NCT05836376) | Michele De Bonis | 2020-11-30 |
| The ENCIRCLE Trial (NCT04153292) | Edwards Lifesciences | 2020-11-12 |
| Transcatheter Mitral Valvuloplasty Pilot Study (NCT04351984) | Duk-Woo Park, MD | 2020-10-20 |
| Treatment of Mitral Regurgitation Using a Minimally Invasive Approach With the HARPOON Device. (NCT04382612) | Edwards Lifesciences | 2020-10-02 |
| SATURN Transcatheter Mitral Valve Replacement for Functional Mitral Regurgitation (NCT04464876) | InnovHeart | 2020-08-19 |
| Dragonfly-M Early Feasibility Study (NCT04528576) | Hangzhou Valgen Medtech Co., Ltd | 2020-07-23 |
| Prospective Analysis of the Feasibility of the PASCAL Spacer Technology for Transcatheter Mitral Valve Repair in an All-comers Cohort (NCT04473092) | University Hospital, Essen | 2020-07-20 |
| An Early Feasibility Study of the HighLife 28mm Trans-Septal Transcatheter Mitral Valve Replacement System (NCT04029337) | HighLife SAS | 2020-07-14 |
| Development of an Algorithm to Differentiate Heart Murmurs Using Electronic Stethoscopes (NCT04400513) | Eko Devices, Inc. | 2020-06-25 |
| 3D Echocardiography and Cardiovascular Prognosis in Mitral Regurgitation (NCT04442828) | Haukeland University Hospital | 2020-04-17 |
| Evaluation of Robotic-assisted Mitral Surgery With the daVinci X Surgical System (NCT04415138) | Cliniche Humanitas Gavazzeni | 2020-03-10 |
| Neochordae Technique in Mitral Valve Repair (NCT04299334) | National Heart Institute, Egypt | 2020-03-02 |
| Multicenter Post-Market Observational Registry of the NeoChord Artificial Chordae Delivery System (NCT04190602) | NeoChord | 2020-02-09 |
| MitraClip EXPAND G4 Study (NCT04177394) | Abbott Medical Devices | 2020-01-17 |
| Impact of Mitral Regurgitation on Coronary Haemodynamics and Instantaneous Effect of Transcatheter Mitral Valve Repair (NCT04245956) | University Hospital, Geneva | 2020-01-08 |
| Early Feasibility EXperience of Posterior Leaflet RestOration to REduce Mitral Regurgitation (NCT04098328) | Polares Medical SA | 2020-01-01 |
| AltaValve Early Feasibility Study Protocol (NCT03997305) | 4C Medical Technologies, Inc. | 2019-12-04 |
| Treatment of Concomitant Mitral Regurgitation by Mitral Valve Clipping in Patients With Successful Transcatheter Aortic Valve Implantation. (NCT04009434) | Technische Universität Dresden | 2019-12-01 |
| 5-Year Follow-Up Safety and Performance Evaluation of the Medtentia Annuloplasty Ring in Adults (NCT04161079) | Medtentia International Ltd Oy | 2019-11-08 |
| Long Term Results of Surgical and Percutaneous Double Orefices Mitral Repair in Patient With p2 Prolapse Causing Degenerative Mitral Regurgitation (NCT05836532) | Michele De Bonis | 2019-10-05 |
| Immediate Suboptimal Result of Mitral Valve Repair: Late Implications in a Matched Cohort Study (NCT05836480) | Michele De Bonis | 2019-10-05 |
| Mitral Regurgitation in Hypertrophic Obstructive Cardiomyopathy: Fix it in a Simple, Effective and Durable Way! (NCT05850026) | Michele De Bonis | 2019-10-05 |
| Pleth Variability Index (PVI) as a Measure of Volume Status During Transcatheter Mitral Valve Repair (NCT03993938) | Henry Ford Health System | 2019-10-01 |
| Transcatheter Treatment for Combined Aortic and Mitral Valve Disease. The Aortic+Mitral TRAnsCatheter (AMTRAC) Valve Registry (NCT04031274) | Rabin Medical Center | 2019-09-01 |
| MiCLASP Post Market Clinical Follow-Up (PMCF) Study (NCT04430075) | Edwards Lifesciences | 2019-08-23 |
| MitralStitch Mitral Valve Repair System for Mitral Regurgitation (NCT04061837) | Xijing Hospital | 2019-08-23 |
| The Effects of Degenerative Mitral Regurgitation on Cardiac Structure and Function, Symptoms, and Exercise Capacity (NCT04051411) | Atlantic Health System | 2019-08-07 |
| Safety and Performance Study of the MitralStitch Repair System. (NCT04080362) | Hangzhou Valgen Medtech Co., Ltd | 2019-07-05 |
| PASCAL vs. MitralClip for Mitral Valve Transchatheter Edge-to-Edge Repair (NCT05865938) | Heinrich-Heine University, Duesseldorf | 2019-06-01 |
| Expanded Study of the HighLife 28mm Trans-septal Trans-catheter Mitral Valve in Patients With Moderate-severe or Severe Mitral Regurgitation and at High Surgical Risk (NCT04029363) | HighLife SAS | 2019-05-28 |
| Cardiovalve Transfemoral Mitral Valve System (NCT03813524) | Cardiovalve Ltd. | 2019-03-26 |
| A Pan-Canadian, Retrospective Evaluation of MitraClip Safety and Efficacy (NCT03592043) | Population Health Research Institute | 2019-01-01 |
| Feasibility Study of the Tendyne Mitral Valve System in Mitral Annular Calcification (NCT03539458) | Abbott Medical Devices | 2018-10-10 |
| Cephea Transseptal Mitral Valve System FIH (NCT03988946) | Cephea Valve Technologies | 2018-08-01 |
| Patient Specific Mitral Valve Modeling for Surgical Planning and Training (NCT03609931) | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2018-07-01 |
| Clinical Trial to Evaluate the Safety and Effectiveness of Using the Tendyne Transcatheter Mitral Valve System for the Treatment of Symptomatic Mitral Regurgitation (NCT03433274) | Abbott Medical Devices | 2018-06-15 |
| Edwards Cardioband European Post-Market Study, MiBAND (NCT03600688) | Edwards Lifesciences | 2018-06-06 |
| Transcatheter Mitral Valve Repair as Bridge Therapy to Heart Transplantation (NCT04293575) | Scientific Institute San Raffaele | 2018-06-01 |
| Primary Mitral Regurgitation Repair (NCT04067635) | Eric Y. Yang, MD PhD | 2018-05-25 |
| Strain Imaging in Patients With Functional Mitral Regurgitation, Treated With MitraClip (NCT04218578) | University of Athens | 2018-05-10 |
| The MitraClip® EXPAND Study of the Next Generation of MitraClip® Devices (NCT03502811) | Abbott Medical Devices | 2018-04-26 |
| AHEAD: European Feasibility Study of the Cardiovalve Transfemoral Mitral Valve System (NCT03339115) | Cardiovalve Ltd. | 2018-04-23 |
| MitraClip NT System Post-marketing Surveillance Study - Japan (NCT03500692) | Abbott Medical Devices | 2018-04-02 |
| ChordArt System for Mitral Regurgitation (NCT03581656) | CoreMedic GmbH | 2018-03-21 |
| Multicentre Study of MITRACLIP® Transcatheter Mitral Valve Repair in Patients With Severe Primary Mitral Regurgitation Eligible for High-risk Surgery (NCT03271762) | Nantes University Hospital | 2018-03-02 |
| Phono- and Electrocardiogram Assisted Detection of Valvular Disease (NCT03458806) | University of California, San Francisco | 2018-02-22 |
| Prospective Treatment Algorithm Guiding Repair of Severe Ischemic Mitral Regurgitation (NCT03292497) | Ottawa Heart Institute Research Corporation | 2018-01-16 |
| Expiratory Flow Limitation and Mechanical Ventilation During Cardiopulmonary Bypass in Cardiac Surgery (NCT02633423) | Ospedale San Raffaele | 2018-01-02 |
| Epicardial Mitral Repair Trial - ENRAPT-MR (NCT03864848) | Mitre Medical Corp. | 2017-12-18 |
| Cardiovalve Transfemoral System - FIM Study (NCT03958773) | Cardiovalve Ltd. | 2017-10-12 |
| SAPIEN M3 EFS: Early Feasibility Study of the Edwards SAPIEN M3 System for the Treatment of Mitral Regurgitation (NCT03230747) | Edwards Lifesciences | 2017-09-14 |
| Caisson Transcatheter Mitral Valve Replacement (TMVR) (NCT03661398) | Caisson Interventional LLC | 2017-07-20 |
| The CINCH-FMR Post-Market Registry: Percutaneous Repair in Functional Mitral Regurgitation (NCT05677568) | Cardiac Dimensions, Inc. | 2017-06-24 |
| Edwards Cardioband System ACTIVE Pivotal Clinical Trial (ACTIVE) (NCT03016975) | Edwards Lifesciences | 2017-06-01 |
| Silent sTROke duriNG MitraClip Implantation (NCT03104556) | Charite University, Berlin, Germany | 2017-04-14 |
| The Right Ventricular Pulmonary Circulation Continuum in Mitral Valve Disease Study (NCT03155373) | Imperial College London | 2017-02-15 |
| The Prognostic Impact of Using High-dose Hydralazine in Severe Systolic Heart Failure With Hemodynamically Significant Mitral Regurgitation (NCT04217135) | Kaohsiung Veterans General Hospital. | 2017-01-01 |
| MitraClip in Acute Mitral Regurgitation (NCT03107455) | Fundación Investigación Sanitaria en León | 2017-01-01 |
| Effect of MitraClip on Acute and Chronic Reverse Cardiac Remodeling Assessed by CMR: The MITRA-REVERSE Study (NCT02924363) | Dipan Shah | 2017-01-01 |
| A Feasibility Registry of Actigraphy Monitoring in Degenerative Mitral Regurgitation Subjects Receiving the MitraClip® Device (NCT02858245) | Abbott Medical Devices | 2016-11-01 |
| Dutch-AMR: Early Mitral Valve Repair Versus Watchful Waiting in Asymptomatic Patients With Severe Mitral Regurgitation (NCT03975998) | UMC Utrecht | 2016-10-01 |
| REPAIR - transcatheteR rEPair of mitrAl Insufficiency With caRdioband System (NCT02703311) | Edwards Lifesciences | 2016-08-01 |
| Incidence of Significant Mitral Regurgitation in Acute Heart Failure Patients (NCT02728739) | Metanoic Health Ltd. | 2016-06-06 |
| MitraClip® After Surgical Mitral Valve Repair (NCT02853955) | LMU Klinikum | 2016-05-01 |
| Degenerative Mitral Regurgitation in Intermediate Risk Patients (NCT02604745) | Northwestern University | 2016-03-01 |
| Remote Monitoring of Patients With Functional Mitral Regurgitation Undergoing Mitraclip Transcatheter Repair (NCT02698150) | Azienda Ospedaliero, Ferrarotto Alessi | 2016-03-01 |