| Low Dose Versus Standard Dose Dexamethasone for Reduction of Swelling in Patients with Primary or Metastatic Brain Tumors (NCT05139043) | City of Hope Medical Center | 2022-04-09 |
| SRS Compared With FSRS for Treatment of Intact Metastatic Brain Disease, FRACTIONATE Trial (NCT05222620) | Mayo Clinic | 2022-03-14 |
| Comparing Whole Brain Radiotherapy Using a Technique That Avoids the Hippocampus to Stereotactic Radiosurgery in Patients With Cancer That Has Spread to the Brain and Come Back in Other Areas of the Brain After Earlier Stereotactic Radiosurgery (NCT04588246) | NRG Oncology | 2021-08-05 |
| Radiosurgery Before Surgery for the Treatment of Brain Metastases (NCT04895592) | Emory University | 2021-07-20 |
| Testing Sacituzumab Govitecan Therapy in Patients With HER2-Negative Breast Cancer and Brain Metastases (NCT04647916) | SWOG Cancer Research Network | 2021-06-08 |
| Testing if High Dose Radiation Only to the Sites of Brain Cancer Compared to Whole Brain Radiation That Avoids the Hippocampus is Better at Preventing Loss of Memory and Thinking Ability (NCT04804644) | NRG Oncology | 2021-06-08 |
| Testing the Addition of an Anti-cancer Drug, Entinostat, to the Usual Chemotherapy and Immunotherapy Treatment (Atezolizumab, Carboplatin and Etoposide) for Previously Untreated Aggressive Lung Cancer That Has Spread (NCT04631029) | National Cancer Institute (NCI) | 2021-04-27 |
| Testing the Addition of an Anti-cancer Drug, Adavosertib, to Radiation Therapy for Patients With Incurable Esophageal and Gastroesophageal Junction Cancers (NCT04460937) | National Cancer Institute (NCI) | 2021-04-09 |
| 18F-FMAU PET/CT and MRI for the Detection of Brain Tumors in Patients With Brain Cancer or Brain Metastases (NCT04752267) | University of Southern California | 2021-02-15 |
| Bintrafusp Alfa and Pimasertib for the Treatment of Patients With Brain Metastases (NCT04789668) | M.D. Anderson Cancer Center | 2021-01-15 |
| A Study to Compare the Administration of Encorafenib + Binimetinib + Nivolumab Versus Ipilimumab + Nivolumab in BRAF-V600 Mutant Melanoma With Brain Metastases (NCT04511013) | SWOG Cancer Research Network | 2021-01-06 |
| Testing of the Anti Cancer Drugs CB-839 HCl (Telaglenastat) and MLN0128 (Sapanisertib) in Advanced Stage Non-small Cell Lung Cancer (NCT04250545) | National Cancer Institute (NCI) | 2020-10-26 |
| Stereotactic Radiosurgery for the Treatment of Patients With Small Cell Lung Cancer Brain Metastasis (NCT04516070) | M.D. Anderson Cancer Center | 2020-08-28 |
| Patient Perceptions Around Quality of Care Through Telemedicine in Neuro-Oncology (NCT04988009) | M.D. Anderson Cancer Center | 2020-08-20 |
| Stereotactic Radiosurgery With Abemaciclib, Ribociclib, or Palbociclib in Treating Patients With Hormone Receptor Positive Breast Cancer With Brain Metastases (NCT04585724) | Emory University | 2020-06-12 |
| Novel MRI Techniques for the Characterization and Treatment Assessment of High Grade Brain Lesions (NCT04132843) | M.D. Anderson Cancer Center | 2020-01-10 |
| Feasibility of Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System Lesions (NCT04047264) | Mayo Clinic | 2020-01-01 |
| Single Fraction Stereotactic Radiosurgery Compared With Fractionated Stereotactic Radiosurgery in Treating Patients With Resected Metastatic Brain Disease (NCT04114981) | Alliance for Clinical Trials in Oncology | 2019-11-19 |
| Genetic Testing in Guiding Treatment for Patients With Brain Metastases (NCT03994796) | Alliance for Clinical Trials in Oncology | 2019-10-17 |
| nTMS in Planning Stereotactic Radiosurgery in Patients With Brain Metastases in the Motor Cortex (NCT04062305) | M.D. Anderson Cancer Center | 2019-09-09 |
| Brigatinib in Treating Patients With ALK and ROS1 Gene Alterations and Locally Advanced or Metastatic Solid Cancers (NCT03868423) | Sameek Roychowdhury | 2019-03-20 |
| Low Dose Ipilimumab With Pembrolizumab in Treating Patients With Melanoma That Has Spread to the Brain (NCT03873818) | M.D. Anderson Cancer Center | 2019-02-21 |
| A Study of a New Drug Combination, Copanlisib and Fulvestrant, in Advanced Breast Cancer (NCT03803761) | National Cancer Institute (NCI) | 2019-02-13 |
| Utility of Perfusion MRI to Detect Radiation Necrosis in Patients With Brain Metastases (NCT03680144) | Emory University | 2018-11-28 |
| HER2-CAR T Cells in Treating Patients With Recurrent Brain or Leptomeningeal Metastases (NCT03696030) | City of Hope Medical Center | 2018-11-27 |
| Pre-Operative or Post-Operative Stereotactic Radiosurgery in Treating Patients With Operative Metastatic Brain Tumors (NCT03750227) | Mayo Clinic | 2018-11-19 |
| Pre-operative SRS or Post-operative SRS in Treating Cancer Patients With Brain Metastases (NCT03741673) | M.D. Anderson Cancer Center | 2018-11-08 |
| DECT in Imaging Patients With Solid Organ Cancer With Intracranial Metastasis (NCT03685539) | M.D. Anderson Cancer Center | 2018-08-24 |
| Regorafenib and Methotrexate in Treating Participants With Recurrent or Metastatic KRAS Mutated Non-Small Cell Lung Cancer (NCT03520842) | Stanford University | 2018-08-14 |
| Dual Time Point FDG PET/MRI Scan in Improving the Imaging Cancer Patients With Brain Metastases (NCT05054998) | M.D. Anderson Cancer Center | 2018-08-03 |
| STAT3 Inhibitor WP1066 in Treating Patients With Recurrent Malignant Glioma or Progressive Metastatic Melanoma in the Brain (NCT01904123) | M.D. Anderson Cancer Center | 2018-07-13 |
| Osimertinib With or Without Bevacizumab in Treating Patients With EGFR Positive Non-small Cell Lung Cancer and Brain Metastases (NCT02971501) | National Cancer Institute (NCI) | 2018-06-27 |
| S1501 Dual Observational and Randomized Cohort Study of Patients With Metastatic HER-2+ Breast Cancer at Risk of Cardiac Toxicity (NCT03418961) | SWOG Cancer Research Network | 2017-11-01 |
| Gadolinium and Ferumoxytol MRI in Diagnosing Patients With Abnormalities in the Central Nervous System (NCT03270059) | OHSU Knight Cancer Institute | 2017-10-06 |
| Blood Brain Barrier Differences in Patients with Brain Tumors Undergoing Surgery (NCT03071913) | Mayo Clinic | 2017-09-20 |
| Mind-Body Intervention in Glioma Couples (NCT03244995) | M.D. Anderson Cancer Center | 2017-08-06 |
| Bevacizumab and Atezolizumab With or Without Cobimetinib in Treating Patients With Untreated Melanoma Brain Metastases (NCT03175432) | M.D. Anderson Cancer Center | 2017-06-15 |
| Testing the Safety of M6620 (VX-970) When Given With Standard Whole Brain Radiation Therapy for the Treatment of Brain Metastases From Non-small Cell Lung Cancer, Small Cell Lung Cancer, or Neuroendocrine Tumors (NCT02589522) | National Cancer Institute (NCI) | 2017-05-22 |
| Ropidoxuridine and Whole Brain Radiation Therapy in Treating Patients With Brain Metastases (NCT02993146) | National Cancer Institute (NCI) | 2017-05-08 |
| APN401 in Treating Patients With Recurrent or Metastatic Pancreatic Cancer, Colorectal Cancer, or Other Solid Tumors That Cannot Be Removed by Surgery (NCT03087591) | Wake Forest University Health Sciences | 2017-04-28 |
| Anti-NY ESO-1 mTCR Peripheral Blood Lymphocytes (NCT02774291) | Albert Einstein College of Medicine | 2017-04-20 |
| Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurgery (NCT03184038) | Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University | 2017-02-21 |
| Nivolumab With Trametinib and Dabrafenib, or Encorafenib and Binimetinib in Treating Patients With BRAF Mutated Metastatic or Unresectable Stage III-IV Melanoma (NCT02910700) | M.D. Anderson Cancer Center | 2016-12-09 |
| Pembrolizumab and Stereotactic Radiosurgery for Melanoma or Non-Small Cell Lung Cancer Brain Metastases (NCT02858869) | Emory University | 2016-10-04 |
| Cisplatin With or Without Veliparib in Treating Patients With Recurrent or Metastatic Triple-Negative and/or BRCA Mutation-Associated Breast Cancer With or Without Brain Metastases (NCT02595905) | National Cancer Institute (NCI) | 2016-09-15 |
| Frameless Fractionated Stereotactic Radiation in Treating Patients With Brain Metastases (NCT02798029) | M.D. Anderson Cancer Center | 2016-08-08 |
| Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors (NCT02754544) | M.D. Anderson Cancer Center | 2016-07-22 |
| SRS and Nivolumab in Treating Patients With Newly Diagnosed Melanoma Metastases in the Brain or Spine (NCT02716948) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2016-06-23 |
| Memantine Hydrochloride and Whole-Brain Radiotherapy With or Without Hippocampal Avoidance in Reducing Neurocognitive Decline in Patients With Brain Metastases (NCT02360215) | NRG Oncology | 2015-07-01 |
| Trametinib With or Without Whole Brain Radiation Therapy in Treating Patients With Brain Metastases (NCT02015117) | National Cancer Institute (NCI) | 2014-04-28 |
| PET-Adjusted Intensity Modulated Radiation Therapy and Combination Chemotherapy in Treating Patients With Stage II-IV Non-small Cell Lung Cancer (NCT02073968) | Albert Einstein College of Medicine | 2013-07-01 |
| Whole-Brain Radiation Therapy or Stereotactic Radiosurgery With or Without Lapatinib Ditosylate in Treating Patients With Brain Metastasis From HER2-Positive Breast Cancer (NCT01622868) | National Cancer Institute (NCI) | 2012-12-06 |
| 18F-FLT PET/CT in Measuring Cell Proliferation in Patients With Brain Tumors (NCT02167204) | University of Washington | 2012-11-01 |
| Stereotactic Radiosurgery in Treating Patients With Greater Than 3 Melanoma Brain Metastases (NCT01644591) | M.D. Anderson Cancer Center | 2012-08-02 |
| Stereotactic Radiosurgery or Whole Brain Radiation Therapy in Treating Patients With Newly Diagnosed Non-melanoma Brain Metastases (NCT01592968) | M.D. Anderson Cancer Center | 2012-08-02 |
| Gadobutrol Versus Gadopentetate Dimeglumine or Gadobenate Dimeglumine Before DCE-MRI in Diagnosing Patients With Multiple Sclerosis, Grade II-IV Glioma, or Brain Metastases (NCT02967380) | University of Southern California | 2011-12-14 |
| RO4929097 and Whole-Brain Radiation Therapy or Stereotactic Radiosurgery in Treating Patients With Brain Metastases From Breast Cancer (NCT01217411) | National Cancer Institute (NCI) | 2010-10-01 |
| Ferumoxytol- and Gadolinium-Labeled MRI in Measuring Tumors Before or After Treatment in Patients With Primary or Metastatic Brain Tumors (NCT00659126) | OHSU Knight Cancer Institute | 2006-11-16 |
| Radiation Therapy and Stereotactic Radiosurgery With or Without Temozolomide or Erlotinib in Treating Patients With Brain Metastases Secondary to Non-Small Cell Lung Cancer (NCT00096265) | National Cancer Institute (NCI) | 2004-10-06 |
| Ferumoxytol in Improving MR Imaging in Patients With High-Grade Brain Tumors or Cerebral Metastases (NCT00103038) | OHSU Knight Cancer Institute | 2004-06-04 |