| Quantitative Assessment of Radiation-induced Neuroinflammation - A Proof of Principle Study (NCT05128903) | St. Jude Children's Research Hospital | 2022-07-05 |
| A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma (NCT04978727) | Children's Oncology Group | 2022-07-01 |
| Individualized Treatment Plan in Children and Young Adults With Relapsed Medulloblastoma and Ependymoma (NCT05057702) | University of California, San Francisco | 2022-02-22 |
| Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer (NCT05106296) | Theodore S. Johnson | 2022-02-08 |
| Flavored, Oral Irinotecan VAL-413 (Orotecan®) Given With Temozolomide for Treatment of Recurrent Pediatric Solid Tumors (NCT04337177) | Valent Technologies, LLC | 2021-10-25 |
| A Study of Bempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant Cancer (NCT04730349) | Bristol-Myers Squibb | 2021-06-03 |
| DFMO as Maintenance Therapy for Molecular High/Very High Risk and Relapsed Medulloblastoma (NCT04696029) | Giselle Sholler | 2021-03-29 |
| Brain Tumor-Specific Immune Cells (IL13Ralpha2-CAR T Cells) for the Treatment of Leptomeningeal Glioblastoma, Ependymoma, or Medulloblastoma (NCT04661384) | City of Hope Medical Center | 2021-03-05 |
| NKG2D-based CAR T-cells Immunotherapy for Patient With r/r NKG2DL+ Solid Tumors (NCT05131763) | Fudan University | 2021-03-01 |
| Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer (NCT04521946) | M.D. Anderson Cancer Center | 2021-01-14 |
| Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms (NCT04541082) | Jazz Pharmaceuticals | 2020-10-26 |
| Efficacy of Dual Task Training on Children With Ataxia After Medulloblastoma Resection (NCT05125666) | Cairo University | 2020-10-01 |
| WP1066 in Children With Refractory and Progressive or Recurrent Malignant Brain Tumors (NCT04334863) | Emory University | 2020-05-04 |
| Infusion of Panobinostat (MTX110) Into the Fourth Ventricle in Children and Adults with Recurrent Medulloblastoma (NCT04315064) | The University of Texas Health Science Center, Houston | 2020-04-21 |
| NKG2D-based CAR T-cells Immunotherapy for Patient With r/r NKG2DL+ Solid Tumors (NCT04270461) | Jiujiang University Affiliated Hospital | 2020-03-17 |
| Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG (NCT04049669) | Theodore S. Johnson | 2019-10-02 |
| 68-Ga DOTATATE PET/MRI in the Diagnosis and Management of Somatostatin Receptor Positive CNS Tumors. (NCT04081701) | Weill Medical College of Cornell University | 2019-09-04 |
| Evaluation of LY2606368 Therapy in Combination With Cyclophosphamide or Gemcitabine for Children and Adolescents With Refractory or Recurrent Group 3/Group 4 or SHH Medulloblastoma Brain Tumors (NCT04023669) | St. Jude Children's Research Hospital | 2019-08-08 |
| Testing the Safety and Tolerability of CX-4945 in Patients With Recurrent Medulloblastoma Who May or May Not Have Surgery (NCT03904862) | Pediatric Brain Tumor Consortium | 2019-07-25 |
| Study Of Palbociclib Combined With Chemotherapy In Pediatric Patients With Recurrent/Refractory Solid Tumors (NCT03709680) | Pfizer | 2019-05-24 |
| EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors (NCT03638167) | Seattle Children's Hospital | 2019-03-19 |
| A Phase 1 Study of ZSP1602 in Participants With Advanced Solid Tumors (NCT03734913) | Guangdong Zhongsheng Pharmaceutical Co., Ltd. | 2019-01-25 |
| HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors (NCT03500991) | Seattle Children's Hospital | 2018-07-26 |
| DOTATOC PET/CT for Imaging NET Patients (NCT03583528) | British Columbia Cancer Agency | 2018-07-11 |
| SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors (NCT03434262) | St. Jude Children's Research Hospital | 2018-03-05 |
| Phase I Study of APX005M in Pediatric Central Nervous System Tumors (NCT03389802) | Pediatric Brain Tumor Consortium | 2018-03-01 |
| Study of Tomotherapy HD in Medulloblastoma (NCT03675230) | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | 2018-01-12 |
| Reduced Craniospinal Radiation Therapy and Chemotherapy in Treating Younger Patients With Newly Diagnosed WNT-Driven Medulloblastoma (NCT02724579) | Children's Oncology Group | 2017-11-17 |
| Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children (NCT03043391) | Istari Oncology, Inc. | 2017-11-07 |
| A Study of Pomalidomide Monotherapy for Children and Young Adults With Recurrent or Progressive Primary Brain Tumors (NCT03257631) | Celgene | 2017-09-18 |
| Rare CNS Tumors Outcomes &Risk (NCT03251989) | National Cancer Institute (NCI) | 2017-08-21 |
| Immune Checkpoint Inhibitor Nivolumab in People With Recurrent Select Rare CNS Cancers (NCT03173950) | National Cancer Institute (NCI) | 2017-07-13 |
| Study Assessing the Feasibility of a Surgery and Chemotherapy-Only in Children With Wnt Positive Medulloblastoma (NCT02212574) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2017-04-04 |
| Dosimetry Guided PRRT With 90Y-DOTATOC (NCT03013387) | Sue O'Dorisio | 2017-01-01 |
| Erlotinib in Combination With Temozolomide in Treating Relapsed/Recurrent/Refractory Pediatric Solid Tumors (NCT02689336) | Washington University School of Medicine | 2016-08-06 |
| Study of Genistein in Pediatric Oncology Patients (UVA-Gen001) (NCT02624388) | University of Virginia | 2016-08-01 |
| Social Cognition and Brain Integrity in Survivors of Pediatric Medulloblastoma (NCT02747576) | St. Jude Children's Research Hospital | 2016-07-13 |
| Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors (NCT02644291) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2016-05-01 |
| Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors (NCT02502708) | NewLink Genetics Corporation | 2015-10-01 |
| HeadStart4: Newly Diagnosed Children (<10 y/o) With Medulloblastoma and Other CNS Embryonal Tumors (NCT02875314) | Parth Patel | 2015-09-01 |
| Impact of Ga-68 DOTATOC PET-CT Imaging in Management of Neuroendocrine Tumors (NCT02441062) | Sue O'Dorisio | 2015-09-01 |
| Phase I/II: Decitabine/Vaccine Therapy in Relapsed/Refractory Pediatric High Grade Gliomas/Medulloblastomas/CNS PNETs (NCT02332889) | University of Louisville | 2015-04-01 |
| Combination Chemotherapy in Treating Younger Patients With Newly Diagnosed, Non-metastatic Desmoplastic Medulloblastoma (NCT02017964) | Children's Oncology Group | 2013-12-24 |
| p28 in Treating Younger Patients With Recurrent or Progressive Central Nervous System Tumors (NCT01975116) | Pediatric Brain Tumor Consortium | 2013-08-01 |
| A Clinical and Molecular Risk-Directed Therapy for Newly Diagnosed Medulloblastoma (NCT01878617) | St. Jude Children's Research Hospital | 2013-06-23 |
| A Phase II Study of Oral LDE225 in Patients With Hedge-Hog (Hh)-Pathway Activated Relapsed Medulloblastoma (MB) (NCT01708174) | Novartis Pharmaceuticals | 2013-05-06 |
| Valproic Acid in Childhood Progressive Brain Tumors (NCT01861990) | Medical University of South Carolina | 2013-05-01 |
| Interest of a Dose Decrease for Radiotherapy Associated With Chemotherapy for Treatment of Standard Risk Adult Medulloblastomas (NCT01857453) | Central Hospital, Nancy, France | 2013-04-10 |
| Safety of 68Ga-DOTA-tyr3-Octreotide PET in Diagnosis of Solid Tumors (NCT01619865) | Sue O'Dorisio | 2012-02-21 |
| Safety and Efficacy Study of TPI-287 in Neuroblastoma and Medulloblastoma (NCT01483820) | Giselle Sholler | 2011-12-01 |
| Auto Transplant for High Risk or Relapsed Solid or CNS Tumors (NCT01505569) | Masonic Cancer Center, University of Minnesota | 2011-10-20 |
| Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors (NCT01331135) | Emory University | 2011-04-01 |
| A Phase I Dose Finding and Safety Study of Oral LDE225 in Children and a Phase II Portion to Assess Preliminary Efficacy in Recurrent or Refractory MB (NCT01125800) | Novartis Pharmaceuticals | 2011-02-01 |
| An East Asian Study of LDE225 (NCT01208831) | Novartis Pharmaceuticals | 2010-10-01 |
| Vaccine Immunotherapy for Recurrent Medulloblastoma and Primitive Neuroectodermal Tumor (NCT01326104) | University of Florida | 2010-09-07 |
| Vaccination With Dendritic Cells Loaded With Brain Tumor Stem Cells for Progressive Malignant Brain Tumor (NCT01171469) | Masonic Cancer Center, University of Minnesota | 2010-09-01 |
| Proton Beam Radiotherapy for Medulloblastoma and Pineoblastoma (NCT01063114) | Massachusetts General Hospital | 2010-04-08 |
| Radiation Therapy and Combination Chemotherapy for Medulloblastoma (NCT02681705) | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | 2010-01-01 |
| A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors (NCT00994071) | National Cancer Institute (NCI) | 2009-09-22 |
| Methionine PET/CT Studies In Patients With Cancer (NCT00840047) | St. Jude Children's Research Hospital | 2009-07-20 |
| Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors (NCT00983398) | OHSU Knight Cancer Institute | 2009-07-09 |
| Dose Finding and Safety of Oral LDE225 in Patients With Advanced Solid Tumors (NCT00880308) | Novartis Pharmaceuticals | 2009-03-01 |
| TPI 287 in Patients With Refractory or Recurrent Neuroblastoma or Medulloblastoma (NCT00867568) | Giselle Sholler | 2009-03-01 |
| Multicenter Pilot-study for the Therapy of Medulloblastoma of Adults (NCT01614132) | University of Regensburg | 2009-01-01 |
| Study of Nifurtimox to Treat Refractory or Relapsed Neuroblastoma or Medulloblastoma (NCT00601003) | Giselle Sholler | 2008-01-14 |
| Combination Chemotherapy Followed By Peripheral Stem Cell Transplant in Treating Young Patients With Newly Diagnosed Supratentorial Primitive Neuroectodermal Tumors or High-Risk Medulloblastoma (NCT00336024) | Children's Oncology Group | 2007-10-22 |
| A Study of Pemetrexed in Children With Recurrent Cancer (NCT00520936) | Eli Lilly and Company | 2007-09-01 |
| Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma/PNET (NCT00392327) | Children's Oncology Group | 2007-05-23 |
| Combination of Irinotecan and Temozolomide in Children With Brain Tumors. (NCT00404495) | Pfizer | 2007-04-01 |
| Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors (NCT01445288) | National Cancer Institute (NCI) | 2006-12-05 |
| Immuno 1: Immune Reconstitution Following Conventional or High-Dose Chemotherapy With Stem Cell Transplant (NCT00231712) | Julius-Maximilians University | 2005-03-01 |
| Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma (NCT00085735) | Children's Oncology Group | 2004-04-30 |
| Hyperfractionated Versus Conventionally Fractionated Radiotherapy in Standard Risk Medulloblastoma (PNET4) (NCT01351870) | Institut Curie | 2004-04-01 |
| High Risk Primitive Neuroectodermal (PNET) Brain Tumors in Childhood (NCT00180791) | Gustave Roussy, Cancer Campus, Grand Paris | 2002-07-01 |
| Low-Dose Radiation and Combination Chemotherapy Following Surgery in Children With Newly Diagnosed Medulloblastoma (NCT00031590) | Children's Hospital of Philadelphia | 2001-04-01 |
| A Pediatric Phase I Trial of RMP-7 and Carboplatin in Brain Tumors (NCT00001502) | National Cancer Institute (NCI) | 1996-04-01 |
| Clinical Studies of Gemcitabine-Oxaliplatin (NCT00407433) | Gustave Roussy, Cancer Campus, Grand Paris | |
| An Intermediate Expanded Use Trial of DFMO (NCT03581240) | Giselle Sholler | |