| A Study of the Drug Selinexor With Radiation Therapy in Patients With Newly-Diagnosed Diffuse Intrinsic Pontine (DIPG) Glioma and High-Grade Glioma (HGG) (NCT05099003) | National Cancer Institute (NCI) | 2022-05-31 |
| Association of Peripheral Blood Immunologic Response to Therapeutic Response to Adjuvant Treatment With Immune Checkpoint Inhibition (ICI) in Patients With Newly Diagnosed Glioblastoma or Gliosarcoma (NCT04817254) | National Cancer Institute (NCI) | 2021-12-08 |
| The PCSK9i Inhibitor Evolocumab - a Surgical Trial of Pharamcodynamics and Kinetics Evaluation (NCT04937413) | Duke University | 2021-10-08 |
| Simultaneous Multinuclear Metabolic MRI in Newly Diagnosed or Recurrent Glioma (NCT05045027) | Jonsson Comprehensive Cancer Center | 2021-09-01 |
| Personalized Vaccine for Patients With Recurrent Malignant Glioma (NCT04943718) | Xuanwu Hospital, Beijing | 2021-07-15 |
| Chemotherapy and Donor Stem Transplant for the Treatment of Patients With High Grade Brain Cancer (NCT04521946) | M.D. Anderson Cancer Center | 2021-01-14 |
| Perampanel for the Reduction of Seizure Frequency in Patients With High-grade Glioma and Focal Epilepsy (NCT04650204) | Mayo Clinic | 2020-12-04 |
| Immunotherapy Before and After Surgery for Treatment of Recurrent or Progressive High Grade Glioma in Children and Young Adults (NCT04323046) | Sabine Mueller, MD, PhD | 2020-10-02 |
| D2C7-IT With Atezolizumab for Recurrent Gliomas (NCT04160494) | Darell Bigner | 2020-02-25 |
| Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma (NCT03919071) | National Cancer Institute (NCI) | 2020-02-20 |
| Combination of PVSRIPO and Atezolizumab for Adults With Recurrent Malignant Glioma (NCT03973879) | Darell Bigner | 2020-02-01 |
| Hypofractionated Stereotactic Radiotherapy With Anlotinib in Patients With Recurrent High-Grade Gliomas (NCT04197492) | Huashan Hospital | 2019-12-16 |
| Effect H2 Water on QoL of Patients Receiving Radiotherapy for High Grade Gliomas. (NCT04175301) | Stony Brook University | 2019-10-31 |
| Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy (NCT03952598) | National Cancer Institute (NCI) | 2019-10-16 |
| Psychological Intervention For Brain Tumor Caregivers (NCT04109209) | Massachusetts General Hospital | 2019-10-09 |
| Mindfulness Meditation in Glioma Patients (NCT03915912) | Duke University | 2019-04-11 |
| BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomas (NCT03749187) | University of California, San Francisco | 2019-04-03 |
| Serial Advanced Magnetic Resonance Imaging Scan for Guidance of Personalized Adaptive Radiotherapy for High Grade Glioma (NCT04771806) | M.D. Anderson Cancer Center | 2019-04-01 |
| 18F-DOPA-PET/MRI Scan in Imaging Elderly Patients With Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma During Planning for a Short Course of Proton Beam Radiation Therapy (NCT03778294) | Mayo Clinic | 2019-03-28 |
| Nivolumab in Patients With IDH-Mutant Gliomas With and Without Hypermutator Phenotype (NCT03718767) | National Cancer Institute (NCI) | 2019-03-27 |
| Psychological Intervention for Caregivers of Patients With Malignant Gliomas (NCT03735498) | Massachusetts General Hospital | 2019-02-08 |
| 9-ING-41 in Patients With Advanced Cancers (NCT03678883) | Actuate Therapeutics Inc. | 2019-01-04 |
| Study of Stereotactic Radiosurgery to the Subventricular Zone in Malignant Gliomas (NCT03956706) | Northwell Health | 2018-12-24 |
| Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With Glioblastoma (NCT03746080) | Lawrence D Recht | 2018-12-04 |
| Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations (NCT03581292) | National Cancer Institute (NCI) | 2018-11-06 |
| Study of the Effect NT-I7 on CD4 Counts in Patients With High Grade Gliomas (NCT02659800) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2018-10-30 |
| AMPLIFYing NEOepitope-specific VACcine Responses in Progressive Diffuse Glioma (NCT03893903) | German Cancer Research Center | 2018-10-19 |
| Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent Medulloblastoma (NCT03615404) | Gary Archer Ph.D. | 2018-10-05 |
| Adoptive Cellular Therapy in Pediatric Patients With High-grade Gliomas (NCT03334305) | University of Florida | 2018-08-27 |
| Memory-Enriched T Cells in Treating Patients With Recurrent or Refractory Grade III-IV Glioma (NCT03389230) | City of Hope Medical Center | 2018-08-14 |
| Quality of Life of Patients With Glioblastoma (GBM) Treated With Tumor-Treating Fields (NCT03501134) | Duke University | 2018-08-08 |
| PEP-CMV in Recurrent MEdulloblastoma/Malignant Glioma (NCT03299309) | Daniel Landi | 2018-06-29 |
| Early Integration of Palliative Care Using the BEACON PROQOL in Patients With High Grade Glioma and Their Caregivers (NCT04630379) | Mayo Clinic | 2018-06-13 |
| Early Palliative Care Intervention in Malignant Glioma (NCT03471546) | Duke University | 2018-05-16 |
| Panitumumab-IRDye800 in Diagnosing Participants With Malignant Glioma Undergoing Surgery (NCT03510208) | Stanford University | 2018-05-16 |
| Ribociclib and Everolimus in Treating Children With Recurrent or Refractory Malignant Brain Tumors (NCT03387020) | Pediatric Brain Tumor Consortium | 2018-01-13 |
| Samotolisib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With TSC or PI3K/MTOR Mutations (A Pediatric MATCH Treatment Trial) (NCT03213678) | National Cancer Institute (NCI) | 2017-11-28 |
| Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial) (NCT03220035) | National Cancer Institute (NCI) | 2017-11-08 |
| Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children (NCT03043391) | Istari Oncology, Inc. | 2017-11-07 |
| Olaparib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With Defects in DNA Damage Repair Genes (A Pediatric MATCH Treatment Trial) (NCT03233204) | National Cancer Institute (NCI) | 2017-09-14 |
| Mind-Body Intervention in Glioma Couples (NCT03244995) | M.D. Anderson Cancer Center | 2017-08-06 |
| Targeted Therapy Directed by Genetic Testing in Treating Pediatric Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphomas, or Histiocytic Disorders (The Pediatric MATCH Screening Trial) (NCT03155620) | National Cancer Institute (NCI) | 2017-07-31 |
| Lerapolturev in Recurrent Malignant Glioma (NCT02986178) | Istari Oncology, Inc. | 2017-06-01 |
| Optune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPG (NCT03033992) | Children's Oncology Group | 2017-04-04 |
| A Study of Varlilumab and IMA950 Vaccine Plus Poly-ICLC in Patients With WHO Grade II Low-Grade Glioma (LGG) (NCT02924038) | Nicholas Butowski | 2017-04-03 |
| TTFields and Pulsed Bevacizumab for Recurrent Glioblastoma (NCT02663271) | University of Florida | 2016-12-19 |
| Neo-adjuvant Evaluation of Glioma Lysate Vaccines in WHO Grade II Glioma (NCT02549833) | Jennie Taylor | 2016-10-17 |
| First in Patient Study for PF-06840003 in Malignant Gliomas (NCT02764151) | Pfizer | 2016-09-09 |
| Hypofractionated Stereotactic Irradiation With Nivolumab, Ipilimumab and Bevacizumab in Patients With Recurrent High Grade Gliomas (NCT02829931) | H. Lee Moffitt Cancer Center and Research Institute | 2016-08-22 |
| Study of Marizomib With Temozolomide and Radiotherapy in Patients With Newly Diagnosed Brain Cancer (NCT02903069) | Celgene | 2016-08-17 |
| Vaccine Therapy for the Treatment of Newly Diagnosed Glioblastoma Multiforme (NCT02465268) | University of Florida | 2016-08-09 |
| Autologous CMV-Specific Cytotoxic T Cells and Temozolomide in Treating Patients With Glioblastoma (NCT02661282) | M.D. Anderson Cancer Center | 2016-06-01 |
| HSV G207 Alone or With a Single Radiation Dose in Children With Progressive or Recurrent Supratentorial Brain Tumors (NCT02457845) | Gregory K. Friedman, MD | 2016-05-01 |
| Phase I Study of Mebendazole Therapy for Recurrent/Progressive Pediatric Brain Tumors (NCT02644291) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2016-05-01 |
| Phase 2 Study of Sym004 for Adult Patients With Recurrent Glioblastoma (NCT02540161) | Annick Desjardins | 2016-02-01 |
| Nivolumab With DC Vaccines for Recurrent Brain Tumors (NCT02529072) | Gary Archer Ph.D. | 2016-01-01 |
| Selinexor in Treating Younger Patients With Recurrent or Refractory Solid Tumors or High-Grade Gliomas (NCT02323880) | Children's Oncology Group | 2015-10-30 |
| Study of Cabiralizumab in Combination With Nivolumab in Patients With Selected Advanced Cancers (NCT02526017) | Five Prime Therapeutics, Inc. | 2015-09-08 |
| Antisense102: Pilot Immunotherapy for Newly Diagnosed Malignant Glioma (NCT02507583) | david andrews | 2015-09-01 |
| MK-3475 in Combination With MRI-guided Laser Ablation in Recurrent Malignant Gliomas (NCT02311582) | Washington University School of Medicine | 2015-08-05 |
| Hypofractionated Stereotactic Irradiation (HFSRT) With Pembrolizumab and Bevacizumab for Recurrent High Grade Gliomas (NCT02313272) | H. Lee Moffitt Cancer Center and Research Institute | 2015-07-28 |
| Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma (NCT02359565) | National Cancer Institute (NCI) | 2015-06-03 |
| Radionecrosis and FDG PET (NCT02391246) | Ottawa Hospital Research Institute | 2015-06-01 |
| D2C7 for Adult Patients With Recurrent Malignant Glioma (NCT02303678) | Darell Bigner | 2015-05-05 |
| Stage 1: Marizomib + Bevacizumab in WHO Gr IV GBM; Stage 2: Marizomib Alone; Stage 3: Combination of Marizomib and Bevacizumab (NCT02330562) | Celgene | 2015-04-15 |
| Molecular Characterization of Gliomas Using a Broad Next Generation Sequencing (NGS)Panel (NCT05486247) | Hellenic Cooperative Oncology Group | 2015-02-04 |
| Adherence Monitoring System in Managing Myelosuppression in Patients With Newly Diagnosed Malignant Gliomas Receiving Temozolomide and Radiation Therapy (NCT02375334) | Wake Forest University Health Sciences | 2015-02-01 |
| Topotecan Using Convection-Enhanced Delivery (CED) in High Grade Glioma (NCT02278510) | Michael Vogelbaum, MD, PhD | 2014-12-09 |
| Early-Phase Safety of Proton Therapy Equipment (NCT02315989) | Chang Gung Memorial Hospital | 2014-08-01 |
| A Pilot Study Using 18F-DOPA PET-guided Radiotherapy in Gliomas (NCT02104310) | Mayo Clinic | 2014-04-08 |
| Combined Cytotoxic and Immune-Stimulatory Therapy for Glioma (NCT01811992) | University of Michigan Rogel Cancer Center | 2014-04-01 |
| Rotating Frame Relaxation and Diffusion Weighted Imaging of Human Gliomas (NCT02186262) | Turku University Hospital | 2014-03-01 |
| Treatment Response and Prognosis in Glioma Patients: Q Cell and Its Biological Characteristics (NCT02047058) | Nanfang Hospital, Southern Medical University | 2014-03-01 |
| 18F-DOPA-PET in Planning Surgery in Patients With Gliomas (NCT02020720) | Mayo Clinic | 2014-01-22 |
| Post-Marketing Surveillance of Long-Term Observation of Gliadel Wafer-Investigation of Vital Prognosis in Patients With High Grade Glioma (NCT02300506) | Eisai Co., Ltd. | 2014-01-10 |
| Stem Cell Radiotherapy and Temozolomide for Newly Diagnosed High-grade Glioma (NCT02039778) | Beth Israel Medical Center | 2013-12-01 |
| 18F-DOPA-PET in Finding Tumors in Patients With Newly Diagnosed Gliomas Undergoing Radiation Therapy (NCT01991977) | Mayo Clinic | 2013-12-01 |
| Dendritic Cell (DC) Vaccine for Malignant Glioma and Glioblastoma (NCT01808820) | Macarena De La Fuente, MD | 2013-08-21 |
| A Phase I Study of High-dose L-methylfolate in Combination With Temozolomide and Bevacizumab in Recurrent High Grade Glioma (NCT01891747) | Vanderbilt-Ingram Cancer Center | 2013-07-01 |
| FMISO-PET in Brain Tumors and SCS Effect (NCT01868906) | Bernardino Clavo, MD, PhD | 2013-06-01 |
| Sorafenib, Valproic Acid, and Sildenafil in Treating Patients With Recurrent High-Grade Glioma (NCT01817751) | Virginia Commonwealth University | 2013-04-11 |
| Post-Marketing Surveillance of Gliadel 7.7mg Implant (All-case Observational Study) (NCT02300532) | Eisai Co., Ltd. | 2013-01-10 |
| Ph II SAHA and Bevacizumab for Recurrent Malignant Glioma Patients (NCT01738646) | Duke University | 2013-01-01 |
| Bevacizumab Beyond Progression (BBP) (NCT01740258) | Duke University | 2013-01-01 |
| Lacosamide in Preventing Seizures in Participants With Malignant Glioma (NCT01432171) | M.D. Anderson Cancer Center | 2012-07-25 |
| CAR T Cell Receptor Immunotherapy Targeting EGFRvIII for Patients With Malignant Gliomas Expressing EGFRvIII (NCT01454596) | National Cancer Institute (NCI) | 2012-05-16 |
| PVSRIPO for Recurrent Glioblastoma (GBM) (NCT01491893) | Istari Oncology, Inc. | 2012-04-25 |
| Image Guided Reirradiation of High-grade Glioma (NCT02025231) | Rigshospitalet, Denmark | 2011-12-01 |
| Phase I/II Adaptive Randomized Trial of Bevacizumab Versus Bevacizumab Plus Vorinostat in Adults With Recurrent Glioblastoma (NCT01266031) | National Cancer Institute (NCI) | 2011-07-12 |
| An Open-label, Phase I/IIa, Dose Escalating Study of 2B3-101 in Patients With Solid Tumors and Brain Metastases or Recurrent Malignant Glioma. (NCT01386580) | BBB-Therapeutics B.V. | 2011-07-01 |
| Low Dose Naltrexone for Glioma Patients (NCT01303835) | Katy Peters | 2011-05-01 |
| A Study of Aminolevulinic Acid Used to Enhance Visualization and Surgical Removal of Brain Tumors (NCT01351519) | MultiCare Health System Research Institute | 2011-05-01 |
| AZD8055 for Adults With Recurrent Gliomas (NCT01316809) | National Cancer Institute (NCI) | 2011-03-04 |
| Dendritic Cell (DC) Activated Cytokine-induced Killer Cell (DCIK) Combined With DC Treatment for Glioma (NCT01235845) | Qingdao University | 2011-01-01 |
| Nuvigil or Placebo in Newly Diagnosed Malignant Glioma (NCT01400958) | H. Lee Moffitt Cancer Center and Research Institute | 2010-12-01 |
| A Phase I Study of AdV-tk + Prodrug Therapy in Combination With Radiation Therapy for Pediatric Brain Tumors (NCT00634231) | Candel Therapeutics, Inc. | 2010-10-01 |
| Study of NPC-07 for Fluorescence-guided Resection of Malignant Gliomas (NCT01167322) | Nobelpharma | 2010-08-01 |
| Avastin/Radiation (XRT)/Temozolomide (Temodar) Followed by Avastin/Temodar/Topotecan for Glioblastoma (NCT01004874) | Duke University | 2009-12-30 |
| Radiosurgery and Avastin for Recurrent Malignant Gliomas (NCT01017250) | Duke University | 2009-12-01 |
| Dendritic Cell Vaccine With Imiquimod for Patients With Malignant Glioma (NCT01792505) | Cedars-Sinai Medical Center | 2009-10-01 |