| Combination of Novel Therapies for CKD Comorbid Depression (NCT04422652) | Stony Brook University | 2020-09-24 |
| Open-Label Safety Study of AXS-05 in Subjects With TRD (EVOLVE) (NCT04634669) | Axsome Therapeutics, Inc. | 2020-09-23 |
| An Augmented Training Program for Preventing Post-Traumatic Stress Injuries Among Diverse Public Safety Personnel (NCT05530642) | University of Regina | 2020-09-22 |
| Unobtrusive Monitoring of Affective Symptoms and Cognition Using Keyboard Dynamics (UnMASCK) (NCT04358900) | University of Illinois at Chicago | 2020-09-17 |
| Feasibility and Acceptability of a Healthy Nordic Diet Intervention in Depressed and Non-depressed Adults (NCT04731454) | Örebro University, Sweden | 2020-09-15 |
| The Safety and Efficacy of Psilocybin in Cancer Patients With Major Depressive Disorder (NCT04593563) | Maryland Oncology Hematology, PA | 2020-09-01 |
| Fisher Wallace Neurostimulation & Depression Study (NCT04541563) | ProofPilot | 2020-08-24 |
| Behavioral and Electrophysiological Effects of Ketamine in Treatment-Resistant Depression (NCT04239963) | Mclean Hospital | 2020-08-17 |
| Mechanistic Evaluation of Response in TRD (MERIT) (NCT04608396) | Axsome Therapeutics, Inc. | 2020-08-13 |
| Behavioral Activation for Major Depression With and Without Mindfulness (NCT04768361) | Hospital Miguel Servet | 2020-08-10 |
| Memory Enhancement by Gamma-hydroxybutyrate vs. Trazodone in Major Depressive Disorder. (NCT04082806) | Erich Seifritz | 2020-08-06 |
| A Pilot Study of Creatine Monohydrate as an Augmenting Agent for ECT in Persons With Major Depressive Disorder (NCT04504253) | University of Utah | 2020-08-03 |
| Opiate Suicide Study in Patients With Major Depression (NCT04116528) | Stanford University | 2020-08-01 |
| Transcranial Near Infrared Radiation and Cerebral Blood Flow in Depression (NCT04366258) | NYU Langone Health | 2020-08-01 |
| The Effect of S-ketamine for Patients Undergoing Electroconvulsive Therapy (ECT) (NCT04399070) | Yan Qiu | 2020-08-01 |
| The Role of PKC Activation in the Immune-inflammatory Mechanism of Major Depressive Depression (NCT04156425) | Shanghai Mental Health Center | 2020-07-01 |
| PSIL201 Long-term Follow-up Study: Psilocybin or Niacin / Major Depressive Disorder (NCT04353921) | Usona Institute | 2020-06-30 |
| Long-term Study With Trazodone Once-a-Day (NCT04295941) | Aziende Chimiche Riunite Angelini Francesco S.p.A | 2020-06-23 |
| Comparison of Vortioxetine and Desvenlafaxine in Adult Patients Suffering From Depression (NCT04448431) | H. Lundbeck A/S | 2020-06-18 |
| Study of Desvenlafaxine in Treating Major Depressive Disorder. (NCT04364997) | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | 2020-06-18 |
| Light Therapy to Improve Symptoms in Pregnant Women With Major Depressive Disorder (NCT04447430) | Guangzhou Psychiatric Hospital | 2020-06-12 |
| Action Tendencies and Prognosis in Major Depressive Disorder (NCT04593537) | King's College London | 2020-06-01 |
| Willkommen Mutterglück: Online CBT for Pregnant and Postpartum Women With Depression and Anxiety (NCT04183946) | University of Zurich | 2020-06-01 |
| Investigation of the Effects of Repetitive Transcranial Magnetic Stimulation on Cognition in Depression (NCT03977038) | Sunnybrook Health Sciences Centre | 2020-05-30 |
| In Vivo Cortical Excitability Modulation in Major Depressive Disorder (NCT05441969) | Fundacao Champalimaud | 2020-05-19 |
| A Study of MD-120 in Patients With Depression (NCT04345471) | Mochida Pharmaceutical Company, Ltd. | 2020-05-18 |
| Virtual Reality Behavioral Activation: An Intervention for Major Depressive Disorder (NCT04268316) | Stanford University | 2020-05-18 |
| Accelerated iTBS for Depressed Patients During the COVID-19 Pandemic (NCT04384965) | Centre for Addiction and Mental Health | 2020-05-12 |
| Establishing TCM Daycare Model and Teaching Mechanism of Depression Patients (NCT04469608) | China Medical University Hospital | 2020-05-11 |
| Study to Assess the Effects of Intranasal Ketamine Along With rTMS for Patients With Treatment-resistant Major Depressive Disorder (TRD) (NCT04352621) | University of Cincinnati | 2020-05-01 |
| The DPP-4 Inhibitor Vildagliptin as Adjunct in Major Depressive Disorder Patients (NCT04410341) | Sadat City University | 2020-05-01 |
| Pilot Study of the Safety and Tolerability of L-DLPFC iTBS rTMS for MDD in MS (NCT04621708) | Sunnybrook Health Sciences Centre | 2020-04-30 |
| Intestinal Flora and Major Depressive Disorders (NCT04347577) | Beijing Chao Yang Hospital | 2020-04-10 |
| A Pilot Randomised Controlled Trial of a Health Champion Intervention (NCT04124744) | King's College London | 2020-04-02 |
| Impact of Covid-19 Pandemic on Patients Receiving Continuation or Maintenance Electroconvulsive Therapy (NCT05633368) | University Hospital, Ghent | 2020-03-31 |
| the Safety, Tolerability, and Pharmacokinetics Study of HEC113995 (NCT04623814) | Sunshine Lake Pharma Co., Ltd. | 2020-03-30 |
| A Phase 2 Trial of OPC-64005 for Major Depressive Disorder (NCT04244253) | Otsuka Pharmaceutical Co., Ltd. | 2020-03-03 |
| Treatment of Major Depressive Disorder in the UK Using TMS Therapy (NCT04217837) | Neuronetics | 2020-03-01 |
| DELPhI Evaluation of Psychiatric Conditions (NCT03842345) | QuantalX Neuroscience | 2020-03-01 |
| Vortioxetine in Patients With Depression and Early Dementia (NCT04294654) | H. Lundbeck A/S | 2020-02-28 |
| Clinical Trial Evaluating Lumateperone Monotherapy in the Treatment of Bipolar Depression or Major Depressive Disorder (NCT04285515) | Intra-Cellular Therapies, Inc. | 2020-02-27 |
| Open-label, Flexible-dose Study of Vortioxetine in Patients With Depression in India (NCT04288895) | H. Lundbeck A/S | 2020-02-20 |
| Biomarkers of Response to Treatment With Frontal Cortex Stimulation for Anxious Depression (NCT03999736) | Mclean Hospital | 2020-02-13 |
| High Dose Accelerated iTBS for Depression (NCT04255784) | Centre for Addiction and Mental Health | 2020-02-06 |
| Clinical Validation of a Combinatorial Pharmacogenomic Approach in Major Depressive Disorder (NCT04615234) | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | 2020-02-01 |
| Augmented Human Intelligence in Major Depressive Disorder (NCT04355650) | Mayo Clinic | 2020-01-27 |
| Transdiagnostic Internet-delivered REBT Intervention for Adolescents' Internalizing Problems (NCT04179526) | Babes-Bolyai University | 2020-01-25 |
| Comparison of Anyu Peibo With Placebo in Treatment of MDD in China (NCT04210973) | Shanghai Mental Health Center | 2020-01-23 |
| DBS for TRD With the Medtronic Summit RC+S (NCT04106466) | Helen Mayberg, MD | 2020-01-21 |
| Mechanism of Action Underlying Ketamine's Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression (NCT03973268) | National Institute of Mental Health (NIMH) | 2020-01-21 |
| The Gut Microbiota of Bipolar and Depression (NCT03062332) | First Affiliated Hospital Xi'an Jiaotong University | 2020-01-16 |
| Evaluation of mHealth for Serious Mental Illness (NCT04068467) | University of Washington | 2020-01-06 |
| Study in Major Depressive Disorder With NMRA-335140 (BTRX-335140) vs Placebo (NCT04221230) | Neumora Therapeutics, Inc. | 2020-01-03 |
| A Pilot Study on Effect of add-on Sulforaphane to SSRIs and Application of Niacin Skin Flush Response Test in Major Depressive Disorder (NCT05148169) | Shanghai Mental Health Center | 2020-01-01 |
| The Phosphodiesterase 5 Inhibitor Sildenafil as an Adjunct to Antidepressants in Major Depressive Disorder Patients (NCT04344678) | Sadat City University | 2020-01-01 |
| rTMS Study in Depression to Evaluate the Relationship Between Brain Plasticity and Clinical Outcome (NCT04032015) | Stanford University | 2020-01-01 |
| Canadian Biomarker Integration Network for Depression (CAN-BIND) - Validation Study (NCT04162522) | University Health Network, Toronto | 2019-12-23 |
| Vortioxetine for Cancer Patients With Depression: An Observational Study (NCT04253678) | University of Malaya | 2019-12-12 |
| tVNS Effects on Motivation in Depression (NCT05120336) | University Hospital Tuebingen | 2019-12-11 |
| Xenon Inhalation Therapy for Major Depressive Disorder and Bipolar Disorder (NCT03748446) | Massachusetts General Hospital | 2019-12-05 |
| A Naturalistic Study of Ketamine for Treatment Resistant Mood Disorders (NCT04226963) | Medical University of Gdansk | 2019-12-04 |
| Does rTMS Induce Synaptic Plasticity? (NCT04311619) | Davidzon, Guido, M.D. | 2019-12-01 |
| Post Marketing Study for the Evaluation of Predictix Antidepressant Clinician Software Support Tool in Prescribing Antidepressant Medication/s for the Treatment of Patients Suffering From Major Depressive Disorder (NCT04138290) | Taliaz Ltd. | 2019-12-01 |
| Adjunctive D-Cycloserine in Major Depressive Disorder (NCT03937596) | University of Calgary | 2019-12-01 |
| A Comparative Study on Efficacy and Safety of add-on Sulforaphane or rTMS to Escitalopram for Major Depressive Disorder With Poor Response to Initial Treatment (NCT05145270) | Shanghai Mental Health Center | 2019-11-30 |
| A Personalized Approach to Effects of Affective Bias Modification on Symptom Change and Rumination (NCT04137367) | University of Oslo | 2019-11-19 |
| Clinical Study of GH001 in Depression (NCT04698603) | GH Research Ireland Limited | 2019-11-12 |
| LSD Therapy for Persons Suffering From Major Depression (NCT03866252) | University Hospital, Basel, Switzerland | 2019-11-01 |
| Genetic Counselling in the Prevention of Mental Health Consequences of Cannabis Use (NCT03601026) | Nova Scotia Health Authority | 2019-11-01 |
| Evaluation of Efficacy of Lycium Barbarum Polysaccharide in Patients With Major Depressive Disorder (NCT04124276) | Guangzhou Psychiatric Hospital | 2019-11-01 |
| Feasibility of Internet-delivered CBT for Adolescents With Depression (NCT04117789) | Karolinska Institutet | 2019-10-14 |
| Transcranial Direct Current Stimulation Therapy for Major Depression (NCT03632434) | University of East London | 2019-10-14 |
| High Intensity Interval Training in Severe Mental Illness (NCT03959735) | King's College London | 2019-10-10 |
| Real-time Biofeedback With 7-Tesla MRI for Treatment of Depression (NCT04138680) | Icahn School of Medicine at Mount Sinai | 2019-10-09 |
| Electrophysiological Correlates of Cognition in Depression (NCT03998748) | Mclean Hospital | 2019-10-08 |
| Cognitive, Psychological and Electrophysiological Attributes to Suicide Among Depressed Patients (NCT04104698) | Mansoura University | 2019-10-01 |
| A Longitudinal Study of Inflammatory Pathways in Depression (NCT04159207) | Van Andel Research Institute | 2019-10-01 |
| Repeated Ketamine Infusions for Comorbid PTSD and MDD in Veterans (NCT04032301) | University of Minnesota | 2019-09-30 |
| Ketamine or Placebo in Patients With Major Depression and Advanced Cancer (NCT04471818) | Instituto Nacional de Cancerologia de Mexico | 2019-09-19 |
| An Investigation of the Relationship Between Omega-3 Fatty Acid Nutrition and Mental Health in Children and Adolescents (NCT04158869) | Swiss Federal Institute of Technology | 2019-09-16 |
| A Study to Evaluate the Efficacy and Safety of Fremanezumab for Preventive Treatment of Migraine in Patients With Major Depressive Disorder (NCT04041284) | Teva Branded Pharmaceutical Products R&D, Inc. | 2019-09-13 |
| Predicting SSRI Efficacy in Veterans With PTSD (NCT04183205) | VA Office of Research and Development | 2019-09-11 |
| Development of Pregnenolone as a Treatment for Depression (NCT03645096) | University of Texas Southwestern Medical Center | 2019-09-01 |
| 8-week of PS128 RCT in Patients With Major Depressive Disorder (NCT04199845) | Taipei Medical University WanFang Hospital | 2019-08-28 |
| Augmenting rTMS With Cognitive Control Training in Major Depressive Disorder (NCT04317495) | University of Michigan | 2019-08-27 |
| Intraoperative Ketamine Versus Saline in Depressed Patients Undergoing Anesthesia for Non-cardiac Surgery (NCT03861988) | Stanford University | 2019-08-22 |
| DBS for Depression (NCT03437928) | Baylor College of Medicine | 2019-08-20 |
| A Study of Individualized Diagnosis and Treatment for Major Depressive Disorder With Atypical Features (NCT04209166) | Shanghai Mental Health Center | 2019-08-12 |
| A Kynurenine Pathway-based Molecular Imaging Study of Individualized Diagnosis and Treatment for Major Depressive Disorder (NCT04208932) | Shanghai Mental Health Center | 2019-08-12 |
| Ketamine IV Classic Protocol : Five Years Follow up (NCT04824157) | Sheba Medical Center | 2019-08-08 |
| A Study to Evaluate SAGE-217 for Prevention of Relapse in Adult Participants With Major Depressive Disorder (NCT04007367) | Biogen | 2019-08-06 |
| Endogenous Opioid Modulation by Ketamine (NCT03051945) | University of Utah | 2019-08-01 |
| The Phosphodiesterase-3 Inhibitor Cilostazol as an Adjunctive to Antidepressants in Patients With Major Depressive Disorder. (NCT04069819) | Sadat City University | 2019-08-01 |
| RCT of Brain Longitudinal Biomarker Study (OPT-Neuro RCT) (NCT05531591) | Centre for Addiction and Mental Health | 2019-08-01 |
| Clinical Study of Escitalopram Oxalate Combined With taVNS in Depression and Concomitant Inflammatory Symptoms (NCT04037111) | Xijing Hospital | 2019-07-23 |
| Closed-Loop Deep Brain Stimulation for Major Depression (NCT04004169) | Andrew Krystal | 2019-07-18 |
| Ketamine for Severe Adolescent Depression: Intermediate-term Safety and Efficacy (NCT03889756) | Yale University | 2019-07-17 |
| Open-Label Safety Study of AXS-05 in Subjects With Depression (NCT04039022) | Axsome Therapeutics, Inc. | 2019-07-08 |
| The Safety, Tolerability, and Pharmacokinetics Study of HEC113995 PA•H2O Tablets in Healthy Subjects (NCT04591301) | Sunshine Lake Pharma Co., Ltd. | 2019-07-04 |
| Hypersomnia in Major Depressive Disorder (NCT04006834) | Chinese University of Hong Kong | 2019-07-01 |