| Inherited Cancer Early Diagnosis (ICED) Study (NCT06163365) | Royal Marsden NHS Foundation Trust | 2022-07-26 |
| Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients (NCT05410977) | Mayo Clinic | 2022-03-30 |
| Mesalamine for Colorectal Cancer Prevention Program in Lynch Syndrome (NCT04920149) | Ann-Sofie Backman | 2022-03-21 |
| Evaluating the Cologuard Test for Use in Lynch Syndrome (NCT04778566) | Geisinger Clinic | 2021-11-01 |
| Evaluation of ArTificial Intelligence System (Gi-Genius) for adenoMa dEtection in Lynch Syndrome. (NCT04909671) | Hospital Clinic of Barcelona | 2021-09-13 |
| Overcoming Barriers to the Uptake of Cascade Screening for Lynch Syndrome: Workbook Feasibility Study (NCT04978350) | UNC Lineberger Comprehensive Cancer Center | 2021-08-01 |
| Tislelizumab for the Treatment of Recurrent Mismatch Repair Deficient Endometrial Cancer (NCT04906382) | Floor Backes, MD | 2021-07-01 |
| Testing the Combination of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) in Children, Adolescent, and Young Adult Patients With Relapsed/Refractory Cancers That Have an Increased Number of Genetic Changes, The 3CI Study (NCT04500548) | National Cancer Institute (NCI) | 2021-05-11 |
| Faecal Microbiota Characterization in Lynch Syndrome (LS) Patients With or Without Colorectal Neoplasia (NCT04791644) | Assistance Publique - Hôpitaux de Paris | 2021-04-20 |
| Implementation of the Families Accelerating Cascade Testing Toolkit (FACTT) for Hereditary Breast and Ovarian Cancer and Lynch Syndrome (NCT04508764) | Washington University School of Medicine | 2021-04-09 |
| DNA Adductomics for Colorectal Cancer Investigation (NCT04865601) | University of Copenhagen | 2021-02-15 |
| Pediatric Reporting of Adult-Onset Genomic Results (NCT03832985) | Geisinger Clinic | 2020-11-25 |
| PD-1 Antibody for The Prevention of Adenomatous Polyps and Second Primary Tumors in Lynch Syndrome Patients (NCT04711434) | Sun Yat-sen University | 2020-11-01 |
| Predictive Factor Study of the Occurrence of Endometrial Cancer in Patients With Lynch Syndrome (NCT04452266) | University Hospital, Lille | 2020-08-14 |
| Family History Study on Cancer Risk (NCT04145388) | Kaiser Permanente | 2020-07-01 |
| Identifying and Caring for Individuals With Inherited Cancer Syndrome (NCT04494945) | OHSU Knight Cancer Institute | 2020-03-09 |
| Prostate Cancer Genetic Risk Evaluation and Screening Study (NCT05129605) | Massachusetts General Hospital | 2020-02-12 |
| Direct Information to At-risk Relatives (NCT04197856) | Umeå University | 2020-02-06 |
| Trial to Compare eConsent With Standard Consent Among Prospective Biobank Participants (NCT04131062) | Geisinger Clinic | 2019-11-01 |
| Registry of Subjects at Risk of Pancreatic Cancer (NCT04095195) | Associazione Italiana per lo Studio del Pancreas | 2019-08-20 |
| Frequency of Endometrial Cancer Precursors Associated with Lynch Syndrome (NCT05257057) | WellSpan Health | 2019-05-08 |
| Omega 3 Fatty Acids in Colorectal Cancer (CRC) Prevention in Patients With Lynch Syndrome (COLYNE) (NCT03831698) | University of Kansas Medical Center | 2019-02-06 |
| MSI in Circulatory DNA of Endometrial Cancer (NCT03744962) | Lei Li | 2018-11-10 |
| Videocapsule Endoscopy in Lynch Syndrome (NCT05704010) | San Raffaele University | 2018-11-01 |
| Nivolumab in Preventing Colon Adenomas in Participants With Lynch Syndrome and a History of Partial Colectomy (NCT03631641) | John Hays | 2018-10-04 |
| Atorvastatin ± Aspirin in Lynch Syndrome Syndrome (NCT04379999) | Fox Chase Cancer Center | 2018-09-10 |
| Universal Endometrial Cancer DNA Sequencing for Detection of Lynch Syndrome and Personalized Care (NCT03460483) | Ohio State University Comprehensive Cancer Center | 2018-03-30 |
| Linked Color Imaging Versus High-definition White Light Endoscopy for the Detection of Polyps in Patients With Lynch Syndrome (LCI-LYNCH) (NCT03344289) | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 2018-01-21 |
| Effect of Chemoprevention by Low-dose Aspirin of New or Recurrent Colorectal Adenomas in Patients With Lynch Syndrome (NCT02813824) | Assistance Publique - Hôpitaux de Paris | 2017-11-14 |
| Combination Chemotherapy With or Without Atezolizumab in Treating Patients With Stage III Colon Cancer and Deficient DNA Mismatch Repair (NCT02912559) | National Cancer Institute (NCI) | 2017-10-16 |
| Liquid Biopsy Evaluation and Repository Development at Princess Margaret (NCT03702309) | University Health Network, Toronto | 2017-08-03 |
| Familial Investigations of Childhood Cancer Predisposition (NCT03050268) | St. Jude Children's Research Hospital | 2017-04-06 |
| Cascade Genetic Testing for Hereditary Breast/Ovarian Cancer and Lynch Syndrome in Switzerland (NCT03124212) | University of Basel | 2017-04-01 |
| Diagnosis of Lynch Syndrome Based on Next-generation Sequencing in Patients Meeting Chinese Lynch Syndrome Criteria (NCT03046849) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2017-03-08 |
| Diagnosis of Lynch Syndrome Based on Next-generation Sequencing in Colorectal Cancer (NCT03047226) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2017-02-28 |
| Weight Management and Health Behavior Intervention in Lowering Cancer Risk for BRCA Positive and Lynch Syndrome Families (NCT04125914) | M.D. Anderson Cancer Center | 2017-01-26 |
| High Definition White-Light Colonoscopy vs. Chromoendoscopy for Surveillance of Lynch Syndrome. (NCT02951390) | Hospital Clinic of Barcelona | 2016-07-01 |
| NBI Versus Indigo Carmine During Colonoscopy in Lynch Syndrome (NCT02570516) | Assistance Publique - Hôpitaux de Paris | 2015-11-01 |
| Universal Screening for Lynch Syndrome in Women With Endometrial and Non-Serous Ovarian Cancer (NCT02494791) | University Health Network, Toronto | 2015-07-01 |
| Pembrolizumab in Treating Younger Patients With Recurrent, Progressive, or Refractory High-Grade Gliomas, Diffuse Intrinsic Pontine Gliomas, Hypermutated Brain Tumors, Ependymoma or Medulloblastoma (NCT02359565) | National Cancer Institute (NCI) | 2015-06-03 |
| Identifying Patients With Hereditary and Familial Colorectal Cancer by Using an Online Risk Tool (NCT02645084) | Prof. Evelien Dekker, MD, PhD | 2015-02-01 |
| Energy Balance Interventions in Increasing Physical Activity in Breast Cancer Gene Positive Patients, Lynch Syndrome-Positive Patients, CLL Survivors or High-Risk Family Members (NCT02194387) | M.D. Anderson Cancer Center | 2014-09-17 |
| Preliminary Evaluation of Septin9 in Patients With Hereditary Colon Cancer Syndromes (NCT02198092) | University of Pennsylvania | 2014-07-01 |
| Pancreatic Cancer Early Detection Program (NCT02206360) | White Plains Hospital | 2014-04-01 |
| Prostate Cancer Screening Among Men With High Risk Genetic Predisposition (NCT02053805) | Rabin Medical Center | 2014-02-01 |
| Naproxen in Preventing DNA Mismatch Repair Deficient Colorectal Cancer in Patients With Lynch Syndrome (NCT02052908) | National Cancer Institute (NCI) | 2014-01-27 |
| The Cancer of the Pancreas Screening-5 CAPS5)Study (NCT02000089) | Johns Hopkins University | 2014-01-06 |
| Integrated Cancer Repository for Cancer Research (NCT02012699) | University of Nebraska | 2013-11-01 |
| Ohio Colorectal Cancer Prevention Initiative (NCT01850654) | Ohio State University Comprehensive Cancer Center | 2012-12-26 |
| Molecular Screening for Lynch Syndrome in Denmark (NCT01845753) | Vejle Hospital | 2012-10-01 |
| Hereditary Colorectal and Associated Tumor Registry Study (NCT00633607) | University of Pittsburgh | 2012-04-01 |
| Integrating Genetic Testing for Lynch Syndrome in a Managed Care Setting (NCT01582841) | Kaiser Permanente | 2012-02-01 |
| I-Scan For Colon Polyp Detection In HNPCC (NCT01823471) | Universitaire Ziekenhuizen KU Leuven | 2010-11-01 |
| Molecular Screening for Lynch Syndrome in Southern Denmark (NCT01216930) | Vejle Hospital | 2010-10-01 |
| Biomarkers in Samples From Patients With Endometrial Cancer (NCT01199250) | Gynecologic Oncology Group | 2010-01-01 |
| Capsule Endoscopy to Screen for Small Bowel Neoplasia in Lynch Syndrome (NCT00898768) | University Medical Center Groningen | 2009-05-01 |
| Chromoendoscopy to Decrease the Risk of Colorectal Neoplasia in Lynch Syndrome (NCT00905710) | University Medical Center Groningen | 2008-09-01 |
| Telemedicine vs. Face-to-Face Cancer Genetic Counseling (NCT00609505) | Duke University | 2008-08-01 |
| Familial Colorectal Cancer Registry in Hispanics (NCT00927680) | University of Puerto Rico | 2007-07-01 |
| Registry for Women Who Are At Risk Or May Have Lynch Syndrome (NCT00508573) | M.D. Anderson Cancer Center | 2007-05-01 |
| The GEOLynch Cohort Study (NCT03303833) | Wageningen University | 2006-07-01 |
| Multi-Organ Screening Recommendations in Patients With Lynch Syndrome (NCT00582296) | Memorial Sloan Kettering Cancer Center | 2004-12-01 |