| A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Adults With Hypertriglyceridemia and Atherosclerotic Cardiovascular Disease (Established or at Increased Risk for), and/or With Severe Hypertriglyceridemia (NCT05355402) | Ionis Pharmaceuticals, Inc. | 2022-05-09 |
| Impact of Foods on Bile Acids, Metabolites, and Inflammation (NCT05245357) | Montana State University | 2022-02-24 |
| Omega-3 Fatty Acid Dietary Intervention (O3DI) (NCT05025943) | Nemours Children's Clinic | 2021-08-16 |
| Effects of Replacing Energy From Solid Fats and Added Sugars (SoFAS) With Avocado (NCT04990817) | Midwest Center for Metabolic and Cardiovascular Research | 2021-06-18 |
| Study to Assess Tricor Therapy Effectiveness in Patients With Metabolic Syndrome (TRISTAN) (NCT04650152) | Abbott | 2020-10-27 |
| A Phase 1, First Time in Humans Study of NST-1024 (NCT04630366) | NorthSea Therapeutics B.V. | 2020-10-27 |
| Assess Efficacy and Safety of Epeleuton in Patients With Hypertriglyceridemia and Type 2 Diabetes (NCT04365400) | Afimmune | 2020-10-13 |
| Nutritional Transitions to More Plant Proteins and Less Animal Proteins: Understanding the Induced Metabolic Reorientations and Searching for Their Biomarkers (ProVegOmics) (NCT04236518) | University Hospital, Clermont-Ferrand | 2020-08-27 |
| Pharmacodynamic Effects of a Free-Fatty Acid Formulation of Omega-3 Pentaenoic Acid in Adults With Hypertriglyceridemia (NCT04177680) | Matinas BioPharma Nanotechnologies, Inc. | 2020-06-03 |
| A First in Human Study of STT-5058, an Antibody That Binds ApoC3 (NCT04419688) | Staten Biotechnology BV | 2020-05-26 |
| Efficacy of Ethyl Icosapentate in Patients With Severe Hypertriglyceridemia (NCT04239950) | Mochida Pharmaceutical Company, Ltd. | 2020-05-09 |
| Long-term Safety and Efficacy Study of MND-2119 in Patients With Hypertriglyceridemia (NCT04221217) | Mochida Pharmaceutical Company, Ltd. | 2020-02-14 |
| Interrupting Prolonged Sitting With Periodic Interval Exercise: Effect on Postprandial Lipemia (NCT04241081) | University of Texas at Austin | 2020-01-01 |
| Intermittent Fasting in Hypertriglyceridemic Overweight or Obese Subjects (NCT04143971) | Shahid Beheshti University | 2019-12-02 |
| Characterization of Fatty Acid Composition of Triglycerides in Patients With Hypertriglyceridemia-induced Acute Pancreatitis (NCT04097990) | Sheba Medical Center | 2019-10-01 |
| Adiponectin, ICAM-1, VCAM-1 Levels and Metabolic Syndrome in Obese Adolescents (NCT05685017) | Universitas Airlangga | 2019-10-01 |
| Dark Chocolate, Cholesterol and Microbiota (NCT03850405) | University of Bari | 2019-05-01 |
| Impact of Plasma Lipids on β Cell Function and Insulin Sensitivity (NCT05181514) | Azienda Ospedaliero, Universitaria Pisana | 2019-04-30 |
| Impact of Aronia Berry Consumption on Inflammation, Metabolites, and the Gut Microbiome (NCT05255718) | Montana State University | 2019-04-27 |
| Impacts of Aronia on Inflammation and the Gut Microbiome (NCT04128839) | Montana State University | 2019-04-27 |
| Study of ARO-APOC3 in Healthy Volunteers, Hypertriglyceridemic Patients and Patients With Familial Chylomicronemia Syndrome (FCS) (NCT03783377) | Arrowhead Pharmaceuticals | 2019-03-08 |
| Postprandial Lipid Metabolism in Patients With Hypertriglyceridemia and Normo-lipidemic Controls: Medium Chain Fatty Acids (MCT) in Comparison to Long-chain, Saturated Fatty Acids (SFA) and Mono-unsaturated Fatty Acids (MUFA) (NCT03846908) | Ludwig-Maximilians - University of Munich | 2019-02-01 |
| Study of ARO-ANG3 in Healthy Volunteers and in Dyslipidemic Patients (NCT03747224) | Arrowhead Pharmaceuticals | 2019-01-07 |
| Translation of Pritikin Program to the Community (NCT03929198) | Washington University School of Medicine | 2018-09-27 |
| Intensive Insulin for Severe/Moderate Hypertriglyceridemia Pancreatitis. (NCT03501680) | First Affiliated Hospital of Wenzhou Medical University | 2018-06-06 |
| Study of Gemcabene in Adults With FPLD (NCT03508687) | Elif Oral | 2018-03-13 |
| A Phase 3 STudy of CaPRe in LOwering Very hiGh TriglYcerides (TRILOGY 2) (NCT03361501) | Grace Therapeutics Inc. | 2018-02-01 |
| Study of ISIS 678354 (AKCEA-APOCIII-LRx) in Participants With Hypertriglyceridemia and Established Cardiovascular Disease (CVD) (NCT03385239) | Akcea Therapeutics | 2018-01-30 |
| A Prospective Observational Program Using Digital Technology Tools to Enhance Patient Adherence to Omacor Therapy (NCT03415152) | Abbott | 2018-01-24 |
| A Phase 3 STudy of CaPRe In LOwering Very hiGh TriglYcerides (TRILOGY 1) (NCT03398005) | Grace Therapeutics Inc. | 2018-01-23 |
| Study of ISIS 703802 in Participants With Hypertriglyceridemia, Type 2 Diabetes Mellitus, and Nonalcoholic Fatty Liver Disease (NCT03371355) | Akcea Therapeutics | 2017-12-21 |
| Intravenous Administration of Insulin and Plasma Exchange on Triglyceride Levels in Early Stage of Hypertriglyceridemia-induced Pancreatitis (NCT03342807) | Peking Union Medical College Hospital | 2017-11-01 |
| Setmelanotide in a Single Patient With Partial Lipodystrophy (NCT03262610) | Rhythm Pharmaceuticals, Inc. | 2017-08-15 |
| The Effect of Omega-3 FA on Hypertriglyceridemia in Patients With T2DM(OCEAN) (NCT03120299) | Shanghai Jiao Tong University School of Medicine | 2017-05-01 |
| Effect of Vascepa on Improving Coronary Atherosclerosis in People With High Triglycerides Taking Statin Therapy (NCT02926027) | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | 2017-03-28 |
| Effects of Two Herbal Dietary Supplements on Lipid Metabolism in Moderate Hypercholesterolemia and Hypertriglyceridemia (NCT02989753) | Valbiotis | 2017-01-01 |
| Effect of Totum-63, Active Ingredient of Valedia, on Glucose and Lipid Homeostasis on Subjects With Prediabetes (NCT02868177) | Valbiotis | 2016-10-01 |
| Feasibility and Acceptability of a Beverage Intervention for Hispanic Adults (NCT02911753) | University of Arizona | 2016-06-01 |
| Effects of Diet Interventions on Monocytes in Metabolic Syndrome (NCT03591588) | Baylor College of Medicine | 2016-04-01 |
| Open-Label Study To Evaluate MN-001 on HDL & Triglyceride in NASH & NAFLD Subjects (NCT02681055) | MediciNova | 2016-03-01 |
| Orlistat for the Treatment of Type I Hyperlipoproteinemia (NCT02767531) | University of Texas Southwestern Medical Center | 2015-12-01 |
| Omega-3-Acid Ethyl Esters 90 Soft Capsules for Lowering Very High Triglycerides (NCT02625870) | Jiangsu HengRui Medicine Co., Ltd. | 2015-12-01 |
| Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS ANGPTL3-LRx in Healthy Volunteers With Elevated Triglycerides and Participants With Familial Hypercholesterolemia (NCT02709850) | Ionis Pharmaceuticals, Inc. | 2015-11-30 |
| A Double-blind Randomized Placebo-controlled Study Comparing Epanova and Fenofibrate on Liver Fat in Overweight Subjects. (NCT02354976) | AstraZeneca | 2015-09-01 |
| AZD0585 Phase III Long-term Study in Japan (NCT02463071) | AstraZeneca | 2015-06-10 |
| The COMPASS Study: A Study of Volanesorsen (Formally ISIS-APOCIIIRx) in Patients With Hypertriglyceridemia (NCT02300233) | Ionis Pharmaceuticals, Inc. | 2015-02-05 |
| A PK and PD Study of Two Formulations of Omega-3 One Gram Capsules (NCT02310022) | Matinas Biopharma, Inc | 2014-11-01 |
| Trial of ARI-3037MO to Reduce Triglyceride Levels in Adults With Severe (≥500 mg/dl) Hypertriglyceridemia (NCT02250105) | Arisaph Pharmaceuticals Inc | 2014-09-01 |
| Effect of Candida Rugosa Lipase on Serum Triglyceride Lowering (NCT05295134) | BIO-CAT, Inc. | 2014-03-13 |
| PK Study Comparing Metformin Eicosapentaenoate to a Combined Dose of Metformin Hydrochloride and Ethyl Ester EPA (NCT02113163) | Thetis Pharmaceuticals LLC | 2014-03-01 |
| Pilot Study To Assess CAT-2003 in Patients With Chylomicronemia (NCT02098278) | Catabasis Pharmaceuticals | 2014-03-01 |
| Apolipoprotein CIII Reduction Via Colchicine (NCT02083510) | Scripps Translational Science Institute | 2014-02-01 |
| Simvastatin and Fenofibrate vs Simvastatin Alone in Patients With Type 2 Diabetes Mellitus and Acute Coronary Syndrome (NCT02015988) | Koval' O., MD | 2014-01-01 |
| PC-300 Tea Effect on Triglyceride Levels (NCT03649269) | Ciprés Grupo Médico CGM SC | 2014-01-01 |
| Epanova® for Lowering Very High Triglycerides II (EVOLVE II) (NCT02009865) | AstraZeneca | 2013-12-16 |
| A Pilot Study to Evaluate the Lipid Effects of TRIA-662 (NCT02008084) | Cortria Corporation | 2013-12-01 |
| Impact of Beans and Oats Snack Bar on Hypertriglyceridemic Women (NCT04966494) | Universidad Autonoma de Queretaro | 2013-10-05 |
| Pilot Study To Assess CAT-2003 in Patients With Severe Hypertriglyceridemia (NCT01968720) | Catabasis Pharmaceuticals | 2013-10-01 |
| Study to Evaluate the 2-Way Interaction Between Multiple Doses of Epanova™ and a Single Dose of Rosuvastatin (Crestor®) (NCT02859129) | AstraZeneca | 2013-09-01 |
| Pilot Study To Assess CAT-2003 in Patients With Hyperlipidemia (NCT01912560) | Catabasis Pharmaceuticals | 2013-07-01 |
| Bioavailability of EPA and DHA From Two Dietary Supplements (NCT01908374) | Arctic Nutrition AS | 2013-07-01 |
| Effect of Therapeutic Phlebotomies on the Triglycerides Concentration in Patients With Hypertriglyceridemia and Hyperferritinemia (NCT02526121) | Instituto Aragones de Ciencias de la Salud | 2013-04-01 |
| Effects Of Consumption Of A Highly Mineralized Sodium Bicarbonated Water On Blood Lipid Profile (NCT01819636) | Neptune | 2013-03-01 |
| Study to Assess the Safety and Tolerability of Single Doses of REGN1500 (NCT01749878) | Regeneron Pharmaceuticals | 2012-12-01 |
| Efficacy and Safety Study of DHA-O in Adults With Hypertriglyceridemia (NCT01737099) | dsm-firmenich Switzerland AG | 2012-11-01 |
| Effects of Acipimox on Mitochondrial Function in Obesity (NCT01488409) | Massachusetts General Hospital | 2012-05-01 |
| Genetic Effect on Omega 3 Fatty Acids for the Treatment of Fatty Liver Disease (NCT01556113) | Yale University | 2012-03-01 |
| Safety, Tolerability, and Pharmacokinetic Study of ISIS ApoC-III Rx in Hypertriglyceridemia (NCT01529424) | Ionis Pharmaceuticals, Inc. | 2012-02-01 |
| Intestines and Liver Contribution to Fasting Postprandial Hypertriglyceridemia (NCT02898142) | Assistance Publique - Hôpitaux de Paris | 2012-02-01 |
| Carbohydrate Metabolism Disorder Frequency in Hypertriglyceridemia Induced by Bexarotene of Cutaneous T Cell Lymphoma (NCT01569724) | Rennes University Hospital | 2012-01-01 |
| Effects of DPP-4 Inhibition on Triglycerides (NCT01527747) | Oregon Health and Science University | 2012-01-01 |
| Vascular and Metabolic Effects of Fenofibrate/Omega vs Fenofibrate (NCT01666041) | Gachon University Gil Medical Center | 2012-01-01 |
| Efficacy of LCQ908 on Cardiovascular Risk (NCT01474434) | Novartis Pharmaceuticals | 2011-12-01 |
| Assess the Safety and Efficacy of NKPL66 (CaPre™) in the Treatment of Mild-to-high Hypertriglyceridemia (NCT01516151) | Grace Therapeutics Inc. | 2011-12-01 |
| The Effect of Multiple Doses of Epanova® on the Multiple-Dose Pharmacokinetics of Simvastatin in Healthy Normal Subjects (NCT01486433) | AstraZeneca | 2011-11-01 |
| A Clinical Trial to Evaluate the Safety and Efficacy of ZYH7 Compared to Fenofibrate in Patients With Dyslipidemia (NCT01539616) | Zydus Lifesciences Limited | 2011-11-01 |
| A Study to Evaluate Fenofibrate Combination With Statin in Chinese Patients With Dyslipidemic (NCT01462877) | Abbott | 2011-10-01 |
| Intervention With n-3 Polyunsaturated Fatty Acids (PUFA)-Supplemented Products in Moderate Hypertriglyceridemic Patients (NCT01437930) | University of Jena | 2011-09-01 |
| TRIal For Efficacy of Capre on hyperTriglyceridemiA (NCT01455844) | Grace Therapeutics Inc. | 2011-09-01 |
| [E]PANOVA Combined With a [S]TATIN in [P]ATIENTS With HYPERT[R]IGLYCER[I]DEMIA to Reduce Non-HDL CHOLES[T]EROL (NCT01408303) | AstraZeneca | 2011-08-01 |
| Interaction of Epanova on Warfarin Pharmacokinetic and Anticoagulant Activity and Comparison of the Effects of Epanova and Lovaza on Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) After Low-fat Meals (NCT01431690) | AstraZeneca | 2011-08-01 |
| Fructose Consumption and Metabolic Dysregulation (NCT01445730) | Marja-Riitta Taskinen | 2011-08-01 |
| An Efficacy and Safety Study of Omacor® in Taiwanese Hypertriglyceridemic Patients (NCT01725646) | Excelsior | 2011-07-01 |
| Fish Oil Supplementation and Vascular Function in Hypertensive Patients With Hypertriglyceridemia (NCT01480687) | Hospital Universitario Pedro Ernesto | 2011-05-01 |
| Vascular and Metabolic Effects of Omega-3 Fatty Acids (NCT01660932) | Gachon University Gil Medical Center | 2011-03-01 |
| Open-Label, Single- and Multiple-Dose Pharmacokinetic Study of Diazoxide Choline (NCT00901823) | Essentialis, Inc. | 2011-03-01 |
| Diazoxide Choline Controlled-Release Tablet (DCCR) for Very High Triglycerides (NCT00973271) | Essentialis, Inc. | 2011-03-01 |
| Effect of Maraviroc on Metabolic Function in Obese Subjects (Phase I) (NCT01133210) | Washington University School of Medicine | 2011-01-01 |
| Efficacy Study of Diazoxide Choline to Treat Hypertriglyceridemia (NCT01211847) | Essentialis, Inc. | 2010-10-01 |
| Effect of Statins on Lipid Levels Following the First Acute Coronary Event (MK-0000-204) (NCT01245738) | Merck Sharp & Dohme LLC | 2010-08-01 |
| Effects of Lovaza on High Density Lipoprotein (HDL) Composition and Function in Hypertriglyceridemia (NCT01180764) | University of Utah | 2010-08-01 |
| Effects of Amino Acids on Regional Lipid Metabolism (NCT01150188) | University of Arkansas | 2010-06-01 |
| The Influence of Ritonavir, Alone and in Combination With Lopinavir, on Fenofibric Acid Pharmacokinetics in Healthy Volunteers (NCT01148004) | National Institutes of Health Clinical Center (CC) | 2010-05-13 |
| Omega-3 Fatty Acid Supplementation in Children (NCT01088776) | The Hospital for Sick Children | 2010-03-01 |
| Effects of Prescription Omega-3 Acids on Glucose and Lipoprotein Lipids in Subjects With Hypertriglyceridemia (NCT01034540) | Provident Clinical Research | 2010-03-01 |
| Crocus Sativus (Saffron) and Berberis Vulgaris (Barberry Fruit) in Metabolic Syndrome (NCT01625442) | Birjand University of Medical Sciences | 2010-01-01 |
| Effect of AMR101 (Ethyl Icosapentate) on Triglyceride (Tg) Levels in Patients on Statins With High Tg Levels (≥ 200 and < 500 mg/dL) (NCT01047501) | Amarin Pharma Inc. | 2009-12-01 |
| Efficacy and Safety of AMR101 (Ethyl Icosapentate) in Patients With Fasting Triglyceride (Tg) Levels ≥ 500 and ≤ 2000 mg/dL (NCT01047683) | Amarin Pharma Inc. | 2009-12-01 |
| Differential Metabolic Effects of Fenofibrate and Fatty Acid (NCT01003847) | Gachon University Gil Medical Center | 2009-11-01 |
| Long-term Efficacy and Safety Study of TAK-085 in Participants With Hypertriglyceridemia (NCT01350999) | Takeda | 2009-11-01 |