| A Single and Multiple Ascending Dose Study of JNJ-64457744 (NCT05423106) | Janssen Research & Development, LLC | 2022-07-04 |
| An Efficacy and Safety Study of a Combination of JNJ-73763989, Nucleos(t)Ide Analogs (NA), and a Programmed Cell Death Protein Receptor-1 (PD-1) Inhibitor in Chronic Hepatitis B Participants (NCT05275023) | Janssen Research & Development, LLC | 2022-06-30 |
| Efficacy and Safety of Avatrombopag for Treating TCP in HBV-ACLF Patients Receiving ALSS Treatment (NCT05382013) | Third Affiliated Hospital, Sun Yat-Sen University | 2022-04-27 |
| The Effect of Education on Drug Compliance and Quality of Life in Hepatitis B Patients (NCT05286216) | Istanbul University - Cerrahpasa | 2022-04-15 |
| A Study on the Safety, Efficacy and Immune Response Following Sequential Treatment With an Anti-sense Oligonucleotide Against Chronic Hepatitis B (CHB) and Chronic Hepatitis B Targeted Immunotherapy (CHB-TI) in CHB Patients Receiving Nucleos(t)Ide Analogue (NA) Therapy (NCT05276297) | GlaxoSmithKline | 2022-03-22 |
| Aerobic Exercise Training in Patients With Chronic Hepatitis B and Hepatic Steatosis (NCT05265026) | Rigshospitalet, Denmark | 2022-03-14 |
| Long-term Safety and Efficacy of Tenofovir Amibufenamide in Patients With CHB (NCT06743438) | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 2022-03-10 |
| Effect of Entecavir Versus Tenofovir on HBV DNA Level in Peripheral Blood Mononuclear Cells (NCT05168293) | Assiut University | 2022-02-01 |
| ANRS HB07 IP-Cure-B Proof of Concept (PoC) Clinical Trial. Educating the Liver Immune Environment Through TLR8 Stimulation Followed by NUC Discontinuation (NCT05045261) | ANRS, Emerging Infectious Diseases | 2022-02-01 |
| Study to Evaluate Safety and Efficacy of ASC42 Combined With ETV and PEG-IFN α-2a in Subjects With HBV (NCT05107778) | Ascletis Pharmaceuticals Co., Ltd. | 2022-01-10 |
| Peginterferon Treatment Study for Inactive Chronic Hepatitis B Patients (NCT05182463) | Third Affiliated Hospital, Sun Yat-Sen University | 2022-01-08 |
| An Experimental Study on the Effect of Tenofovir Amibufenamide on Blood Lipid During Anti-HBV Treatment (NCT05398393) | Union Hospital, Tongji Medical College, Huazhong University of Science and Technology | 2022-01-01 |
| Clinical Characteristics, Natural Outcome and Treatment Optimization of Refractory (NCT05376124) | First Affiliated Hospital Xi'an Jiaotong University | 2022-01-01 |
| A Study of JNJ-73763989, JNJ-64300535, and Nucleos(t)Ide Analogs in Virologically Suppressed, Hepatitis B e Antigen (HBeAg)- Negative Participants With Chronic Hepatitis B Virus Infection (NCT05123599) | Janssen Research & Development, LLC | 2021-12-06 |
| A Study of JNJ-73763989, Pegylated Interferon Alpha-2a and Nucleos(t)Ide Analogs in Participants With Chronic Hepatitis B Virus Infection (NCT05005507) | Janssen Research & Development, LLC | 2021-11-03 |
| Evaluation Freethiadine Tolerance in Healthy Subjects and Patients With Chronic Hepatitis B, Pharmacokinetics Characteristics and Antiviral Activity of Ⅰ Phase of Study (NCT05391360) | Sunshine Lake Pharma Co., Ltd. | 2021-10-11 |
| Safely Discontinue Antiviral Treatment in Patients With Chronic Hepatitis B (NCT04782375) | Asan Medical Center | 2021-09-01 |
| Effectiveness of Antiviral Treatment in Cirrhotic Patients with Low-level Hepatitis B Virus DNA Levels (NCT04780204) | Asan Medical Center | 2021-08-23 |
| Study of VIR-2218, VIR-3434, and/or PEG-IFNα in Subjects With Chronic Hepatitis B Virus Infection (NCT04856085) | Vir Biotechnology, Inc. | 2021-07-11 |
| A Phase II Study of Hepalatide in Subjects With Chronic Hepatitis B (NCT04426968) | Shanghai HEP Pharmaceutical Co., Ltd. | 2021-06-18 |
| A Multiple-dose Study in Chinese Subjects to Evaluate Safety,Tolerability,PK and PD of ZM-H1505R (NCT05470829) | Shanghai Zhimeng Biopharma, Inc. | 2021-05-27 |
| Efficacy and Safety of TAF in Patients With Suboptimal Response to Other Nucleos(t)Ides (NCT04201808) | New Discovery LLC | 2021-05-01 |
| Predictive Model for Prognosis of Chronic HBV Infection Mothers (NCT04805034) | First Affiliated Hospital Xi'an Jiaotong University | 2021-04-16 |
| Study to Investigate the Safety and Efficacy of BRII-835 and BRII-179 Combination Therapy Treating Chronic Hepatitis B Virus (HBV) Infection (NCT04749368) | Brii Biosciences Limited | 2021-04-12 |
| Preventing Mother-to-child Transmission of Hepatitis B Virus With Tenofovir Alafenamide (TAF) (NCT05177926) | Nanfang Hospital, Southern Medical University | 2021-04-04 |
| Linkage to Care and Treatment of Chronic HBV Patients (NCT06658678) | The University of Hong Kong | 2021-04-03 |
| A Study of Safety and Efficacy of ATI-2173 in Combination With Tenofovir Disoproxil Fumarate in Subjects With Chronic Hepatitis B Virus Infection and in Subjects With Hepatitis D Virus Coinfection (NCT04847440) | Antios Therapeutics, Inc | 2021-03-30 |
| Molecular Epidemiology of Hepatitis B in Cayenne General Hospital, French Guiana (NCT04886102) | Centre Hospitalier de Cayenne | 2021-02-11 |
| A Study of JNJ-73763989, JNJ-56136379, Nucleos(t)Ide Analogs, and Pegylated Interferon Alpha-2a in Virologically Suppressed Participants With Chronic Hepatitis B Virus Infection (NCT04667104) | Janssen Research & Development, LLC | 2021-02-01 |
| HepTcell Immunotherapy in Patients With Inactive Chronic Hepatitis B (CHB) (NCT04684914) | Altimmune, Inc. | 2020-12-26 |
| Real World Study About Anti-viral Regimen Adjustment on Achieving Complete Response in CHB Patients (NCT04724785) | The Second Affiliated Hospital of Chongqing Medical University | 2020-12-01 |
| User-friendly HIV Testing and Counseling Services (NCT04585165) | Institut de Recherche pour le Developpement | 2020-10-19 |
| Evaluation HEC121120 Tolerance in Healthy Subjects and Patients With Chronic Hepatitis B, Pharmacokinetics Characteristics and Antiviral Activity of Ⅰ Phase of Study (NCT04536532) | Sunshine Lake Pharma Co., Ltd. | 2020-10-09 |
| Effects of Pioglitazone and Evogliptin on Hepatic Fibrosis in Patients With Chronic Hepatitis B With Type 2 Diabetes (NCT05473806) | Seung Up Kim | 2020-09-18 |
| A Study of JNJ-73763989, Pegylated Interferon Alpha-2a, Nucleos(t)Ide Analog (NA) With or Without JNJ-56136379 in Treatment-naive Participants With Hepatitis B e Antigen (HBeAg) Positive Chronic Hepatitis B Virus (HBV) Infection (NCT04439539) | Janssen Research & Development, LLC | 2020-09-14 |
| A Cross-sectional Study for Renal Function of Patients With Chronic Hepatitis B in China (NCT04538651) | Sun Yat-sen University | 2020-08-31 |
| Study of VIR-2218 in Patients With Chronic Hepatitis B in Mainland China (NCT04507269) | Brii Biosciences Limited | 2020-08-18 |
| Study of IMC-I109V in Non-cirrhotic HBeAg-negative Chronic HBV Infection (NCT05867056) | Immunocore Ltd | 2020-08-12 |
| A Trial To Evaluate The Efficacy And Safety Of Multiple Combination Therapies In Participants With Chronic Hepatitis B (NCT04225715) | Hoffmann-La Roche | 2020-07-05 |
| Study of EYP001a to Assess Its Safety and Anti-viral Effect in CHB Patients in Combination With NA (ETV or TD) (NCT04465916) | Enyo Pharma | 2020-05-12 |
| A Study to Evaluate the Efficacy and Safety of Therapeutic Hepatitis B Vaccine (NCT04289987) | Aribio Lab Co., Ltd. | 2020-02-19 |
| National Cohort of Patients Co-infected With Hepatitis B and Delta Viruses (NCT04166266) | ANRS, Emerging Infectious Diseases | 2020-02-19 |
| A Phase 1 Double-Blinded Study for Safety, Tolerability, Pharmacokinetics, and Antiviral Activity of ATI-2173 in Healthy Subjects and Subjects With Chronic Hepatitis B Virus Infection (NCT04248426) | Antios Therapeutics, Inc | 2020-02-05 |
| Maternal Therapy With TAF Versus TDF to Prevent Vertical Transmission of Hepatitis B (NCT04211805) | New Discovery LLC | 2020-01-27 |
| A Study to Evaluate a Study Drug, DCB-BO1202, for Alleviating Liver Fibrosis in Liver Cancer Patients (NCT02289300) | A2 Healthcare Taiwan Corporation | 2020-01-01 |
| Evaluate the Efficacy and Safety of HLX10 in Chronic Hepatitis B Patients (NCT04133259) | Henlix, Inc | 2019-12-31 |
| A Study of JNJ 73763989+JNJ 56136379+Nucleos(t)Ide Analog (NA) Regimen Compared to NA Alone in e Antigen Negative Virologically Suppressed Participants With Chronic Hepatitis B Virus Infection (NCT04129554) | Janssen Sciences Ireland UC | 2019-11-06 |
| Risk of Hepatocellular Carcinoma in Patients Treated With ETV vs TDF for Chronic Hepatitis B With Compensated Cirrhosis (NCT04160897) | Qing XIe | 2019-10-22 |
| Evaluating the Safety and Efficacy of Inarigivir in Non-cirrhotic Treatment Naive Subjects Infected With Hepatitis B Virus (NCT04059198) | F-star Therapeutics, Inc. | 2019-10-10 |
| A Study of Different Combination Regimens Including JNJ-73763989 and/or JNJ-56136379 for the Treatment of Chronic Hepatitis B Virus Infection (NCT03982186) | Janssen Sciences Ireland UC | 2019-08-01 |
| Evaluating the Safety and Efficacy of Inarigivir in Non-cirrhotic, Hepatitis B e Antigen-negative Subjects Infected With HBV Virus and Receiving or Stopping Treatment With a NUC Inhibitor (NCT04023721) | F-star Therapeutics, Inc. | 2019-06-18 |
| Evaluating the Effects of Inarigivir on Immune Response and Viral Markers in Chronic Hepatitis B Patients (NCT03932513) | F-star Therapeutics, Inc. | 2019-04-11 |
| Chronic HBV Infection in Pregnant Women Taking TAF to Prevent Vertical Transmission (NCT04237376) | New Discovery LLC | 2019-04-09 |
| Safety, Efficacy, Immunogenicity Study of GSK Biologicals' HBV Viral Vector and Adjuvanted Proteins Vaccine (GSK3528869A) in Adult Patients With Chronic Hepatitis B Infection (NCT03866187) | GlaxoSmithKline | 2019-03-28 |
| Prediction Model Based on Computed Tomography Liver Volume for the Short-term Mortality in Hepatitis B Related Acute-on-Chronic (NCT03977857) | First Affiliated Hospital Xi'an Jiaotong University | 2019-03-01 |
| Tenofovir Alafenamide With Fine Needle Aspiration Biopsy in Chronic Hepatitis B: (NCT04070079) | University Health Network, Toronto | 2019-01-29 |
| Ribavirin to Enhance Hepatitis B Virus Nucleotide Analog Antiviral Activity (NCT03759782) | Ottawa Hospital Research Institute | 2019-01-10 |
| Study of Safety and Tolerability of DCR HBVS (NCT03772249) | Dicerna Pharmaceuticals, Inc., a Novo Nordisk company | 2018-12-28 |
| The Norwegian Nucleoside Analogue Stop Study (NCT03681132) | Oslo University Hospital | 2018-09-20 |
| The Clinical Cure Project of Chronic Hepatitis B in China (NCT04035837) | Third Affiliated Hospital, Sun Yat-Sen University | 2018-05-16 |
| Treatment Outcomes in Chronic Hepatitis B Patients on Sequential Therapy With Tenofovir Alafenamide (TAF) (NCT03471624) | Stanford University | 2018-05-01 |
| A First-In-Human Study to Evaluate Safety, Tolerability, Reactogenicity, and Immunogenicity of JNJ-64300535, a DNA Vaccine, Administered by Electroporation-Mediated Intramuscular Injection, in Participants With Chronic Hepatitis B Who Are on Stable Nucleos(t)Ide Therapy and Virologically Suppressed (NCT03463369) | Janssen Sciences Ireland UC | 2018-04-18 |
| A Prospective,Observational Follow-up Study of Nucleoside Treated Patients With Chronic Hepatitis B (OCEAN Study) (NCT03358108) | Qin Ning | 2018-02-27 |
| Drug Drug Interaction Study for EYP001 With Entecavir (NCT03469583) | Enyo Pharma | 2018-02-12 |
| Evaluate the Efficacy and Safety to Tenofovir Disoproxil in Chronic Hepatitis B Patients (NCT03485534) | Daewoong Pharmaceutical Co. LTD. | 2018-01-23 |
| A Study of Switching From Entecavir to Tenofovir Disoproxil Fumarate in Subjects With Chronic Hepatitis B (NCT03258710) | GlaxoSmithKline | 2017-10-02 |
| Evaluation of the Safety and Pharmacology of EYP001 in HBV Subjects (NCT03272009) | Enyo Pharma | 2017-09-21 |
| A Study Evaluating AL-3778 in Combination With Peginterferon Alpha-2a in Chronic Hepatitis B Subjects (NCT03125213) | Alios Biopharma Inc. | 2017-09-12 |
| Efficacy and Safety of DA-2802 in Chronic Hepatitis B Patients (NCT02967939) | Dong-A ST Co., Ltd. | 2017-03-28 |
| Biologic Basis of Liver Cancer From Chronic Hepatitis B (NCT03300414) | University of California, Davis | 2017-03-20 |
| The Study of Two Different Chinese Traditional Medicine Treatment on Chronic Hepatitis B (NCT03018821) | Xi'an Traditional Medicine Hospital | 2017-01-01 |
| Clinical and Basic Research of ETV Plus GM-CSF in Chronic Hepatitis B Patients (NCT03164889) | Beijing 302 Hospital | 2017-01-01 |
| A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of RO7049389 in Healthy Volunteers and Chronic Hepatitis B Virus (HBV) Infected Participants (NCT02952924) | Hoffmann-La Roche | 2016-12-14 |
| A Study in Healthy Volunteers and in Participants With Chronic Hepatitis B to Assess Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single and Multiple Doses of RO7020531 (NCT02956850) | Hoffmann-La Roche | 2016-12-12 |
| Cohort Study on People Who Inject Drugs in Senegal (NCT03459768) | French National Agency for Research on AIDS and Viral Hepatitis | 2016-08-24 |
| A Long Term Follow-up Study of Patients From the REP 301 Protocol (NCT02876419) | Replicor Inc. | 2016-08-01 |
| A Study of ALN-HBV in Healthy Adult Volunteers and Non-cirrhotic Patients With Chronic Hepatitis B Virus (HBV) Infection (NCT02826018) | Alnylam Pharmaceuticals | 2016-06-24 |
| REALM China Extension Study (NCT02974829) | Nanfang Hospital, Southern Medical University | 2016-05-01 |
| Cameroon Baptist Convention Health Board Chronic Hepatitis B Cohort Study (NCT02766933) | Mayo Clinic | 2016-05-01 |
| New Strategy Study of Functional Cure of Chronic Hepatitis B (NCT02605252) | Third Affiliated Hospital, Sun Yat-Sen University | 2016-03-01 |
| Use of TDF in Patients With Inactive Chronic Hepatitis B Infection (NCT02600117) | University Health Network, Toronto | 2016-01-26 |
| Study of ARB-001467 in Subjects With Chronic HBV Infection Receiving Nucleos(t)Ide Analogue Therapy (NCT02631096) | Arbutus Biopharma Corporation | 2015-12-01 |
| A Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of RO7020322 Following Oral Administration in Healthy Participants and Chronic Hepatitis B Patients (NCT02604355) | Hoffmann-La Roche | 2015-11-28 |
| Active Drug Comparative Trial to Evaluate the Antiviral Activity and Safety in Chronic Hepatitis B Patients (NCT02588937) | Chong Kun Dang Pharmaceutical | 2015-10-01 |
| Safety and Pharmacokinetic Study of Hepalatide(L47) in Healthy Volunteers (NCT02612506) | Shanghai HEP Pharmaceutical Co., Ltd. | 2015-10-01 |
| A Hepatitis B With Hepatic Steatosis Study (NCT02392598) | Fatty Liver and Alcoholic Liver Disease Study Group, China | 2015-08-01 |
| Observational Study on Pregnant Women With Chronic Hepatitis B and Their Infants (NCT03539016) | Nanfang Hospital, Southern Medical University | 2015-07-01 |
| A Phase II Clinical Trial of Hydronidone Capsules(F351) in Patients With Liver Fibrosis Induced by HBV Chronic Hepatitis (NCT02499562) | Shanghai Genomics, Inc. | 2015-06-25 |
| The Safety of Anti-viral Therapy in Preventing HBV MTCT in Pregnant Women After Discontinuation (NCT03468907) | Third Affiliated Hospital, Sun Yat-Sen University | 2015-06-01 |
| A Study of Treatment With RO6864018 in Virologically Suppressed Participants With Chronic Hepatitis B Virus (HBV) Infection (NCT02391805) | Hoffmann-La Roche | 2015-05-17 |
| Compare Continuing Lamivudine Plus Adefovir or Adefovir Versus Switching to Entecavir Plus Adefovir in Patients With LAM-resistant Chronic Hepatitis B (NCT02482272) | Asan Medical Center | 2015-05-01 |
| EFFORT Further Extension Study (NCT02826070) | Nanfang Hospital, Southern Medical University | 2015-04-01 |
| Efficacy and Safety Study of Tenofovir Disoproxil Fumarate (TDF) in Chinese Chronic Hepatitis B (CHB) Subjects With Advanced Fibrosis & Compensated Cirrhosis (NCT02224456) | GlaxoSmithKline | 2015-03-25 |
| Tenofovir Disoproxil Fumarate (TDF) 300mg 3 Years RD Therapy Chinese Chronic Hepatitis B (CHN) CHB Multiple Nucleos(t)Ide Analogues (NAs) Failure Points Pts PH4 PMS Study (NCT02195518) | GlaxoSmithKline | 2015-03-18 |
| Study of Antiretroviral Therapy to Prevent HBV Intrauterine Infection (NCT02719808) | First Affiliated Hospital Xi'an Jiaotong University | 2015-03-01 |
| Emtricitabine for Naive Child Chinese Chronic Hepatitis B Patients (NCT02327676) | Asian-Pacific Alliance of Liver Disease, Beijing | 2015-01-01 |
| Emtricitabine Plus Adefovir Dipivoxil for Naive Chinese HBV Related Cirrhosis Patients (NCT02327689) | Asian-Pacific Alliance of Liver Disease, Beijing | 2015-01-01 |
| Emtricitabine for Naive Chinese Pregnant Chronic Hepatitis B Patients (NCT02327702) | Asian-Pacific Alliance of Liver Disease, Beijing | 2015-01-01 |
| Emtricitabine for Prevention of Vertical Transmission of HBV in Chinese Pregnant HBsAg Positive Patients (NCT02327715) | Asian-Pacific Alliance of Liver Disease, Beijing | 2015-01-01 |
| An Observational Study in Participants With Chronic Hepatitis B (CHB) Receiving Therapy With Peginterferon Alfa-2a 40 Kilodaltons (kD) (PEGASYS) - The PRO B Study (NCT02201407) | Hoffmann-La Roche | 2014-12-18 |