| Investigation of Sulindac (HLX-0201) and Gaboxadol (HLX-0206) in Male Fragile X Syndrome Patients Aged 13-40 (NCT04823052) | Healx Limited | 2022-05-25 |
| A Randomized Study of BPN14770 in Male Adolescents (Aged 9 to < 18 Years) With Fragile X Syndrome (NCT05163808) | Tetra Discovery Partners | 2022-03-29 |
| Metformin in Children With Fragile X Syndrome (NCT05120505) | Children's Hospital of Fudan University | 2021-12-29 |
| ERG/5-HTP in Fragile X Syndrome (FXS) (NCT05030129) | Elizabeth Berry-Kravis | 2021-10-07 |
| Clinical Study of Cannabidiol in Children, Adolescents, and Young Adults With Fragile X Syndrome (NCT04977986) | Zynerba Pharmaceuticals, Inc. | 2021-09-13 |
| Validation of Optical Genome Mapping for the Identification of Constitutional Genomic Variants in a Postnatal Cohort (NCT05295277) | Bionano Genomics | 2020-11-30 |
| NIPD on cffDNA for Triplet Repeat Diseases (NCT04698551) | University Hospital, Montpellier | 2020-09-01 |
| Metformin in Patients With Fragile X (NCT04141163) | Rowan University | 2019-10-29 |
| A Trial of Metformin in Individuals With Fragile X Syndrome (Met) (NCT03862950) | University of Alberta | 2019-05-24 |
| Parent and Infant Inter(X)Action Intervention (PIXI) (NCT03836300) | RTI International | 2018-11-30 |
| Open Label Extension to Assess the Long-Term Safety and Tolerability of ZYN002 in Children and Adolescents With FXS (NCT03802799) | Zynerba Pharmaceuticals, Inc. | 2018-11-09 |
| Early Check: Expanded Screening in Newborns (NCT03655223) | RTI International | 2018-10-15 |
| Metformin in Children and Adults With Fragile X Syndrome (NCT03722290) | Université de Sherbrooke | 2018-09-01 |
| A 2-Period Crossover Study of BPN14770 in Adults Males With Fragile X Syndrome (NCT03569631) | Tetra Discovery Partners | 2018-07-09 |
| A Trial of Metformin in Individuals With Fragile X Syndrome (NCT03479476) | University of California, Davis | 2018-04-30 |
| Pediatric Exploratory Research Study of EGCG Use and Safety (PERSEUS) (NCT03624556) | Parc de Salut Mar | 2018-01-29 |
| An Initial Study of AZD7325 in Adults With Fragile X Syndrome (NCT03140813) | Children's Hospital Medical Center, Cincinnati | 2018-01-16 |
| AFQ056 for Language Learning in Children With FXS (NCT02920892) | Elizabeth Berry-Kravis | 2017-08-17 |
| Cooperative Parent Mediated Therapy in Children With Fragile X Syndrome and Williams Syndrome (NCT04610424) | Bambino Gesù Hospital and Research Institute | 2017-05-17 |
| Single Dose Pharmacokinetic (PK) Study (NCT03109756) | Healx AI | 2017-04-03 |
| Treatment of Disruptive Behaviors in Fragile X Syndrome (NCT03510156) | Stanford University | 2016-07-01 |
| Pediatric Patients With Metabolic or Other Genetic Disorders (NCT02769949) | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 2016-05-03 |
| Neurophysiological and Acute Pharmacological Studies in FXS Patients (NCT02998151) | Children's Hospital Medical Center, Cincinnati | 2016-01-01 |
| Combining Lovastatin and a Parent-Implemented Language Intervention for Fragile X Syndrome (NCT02642653) | University of California, Davis | 2016-01-01 |
| Effects of Social Gaze Training on Brain and Behavior in Fragile X Syndrome (NCT02616796) | Stanford University | 2015-04-01 |
| A Safety Study of NNZ-2566 in Patients With Fragile X Syndrome (NCT01894958) | Neuren Pharmaceuticals Limited | 2014-01-01 |
| Study of Acamprosate in Fragile x Syndrome (NCT01911455) | Children's Hospital Medical Center, Cincinnati | 2013-08-27 |
| "Using Epigallocatechin Gallate (EGCG) and Cognitive Training to Modulate Cognitive Performance in Patients With Fragile X Syndrome" (TESFX) (NCT01855971) | Parc de Salut Mar | 2013-06-11 |
| EXPLAIN -FragilE X Registry: An exPlorative Longitudinal Study for chAracterIzation, Treatment Pathways and patieNt-related Outcomes (NCT01711606) | Novartis Pharmaceuticals | 2013-03-01 |
| A Study of RO4917523 in Pediatric Patients With Fragile X Syndrome (NCT01750957) | Hoffmann-La Roche | 2013-02-01 |
| Cognitive Training for Fragile X Syndrome (NCT02747394) | University of California, Davis | 2013-01-01 |
| Validation of Saliva in the Esoterix Genetic Laboratories Fragile X Assay (NCT01616589) | Esoterix Genetic Laboratories, LLC | 2012-07-01 |
| Clinical Study to Assess the Pharmacokinetics, Safety and Tolerability of Single and Multiple Oral Doses of AFQ056 in Children With Fragile X Syndrome (FXS) (NCT01482143) | Novartis Pharmaceuticals | 2012-03-01 |
| Trial of Sertraline to Treat Children With Fragile X Syndrome (NCT01474746) | Randi J. Hagerman, MD | 2012-01-01 |
| Long-term, Safety and Tolerability Study of AFQ056 in Adolescent Patients With Fragile X Syndrome (Open-label) (NCT01433354) | Novartis Pharmaceuticals | 2011-11-01 |
| An Open Label Extension Study in Subjects With Fragile X Syndrome (NCT01555333) | Seaside Therapeutics, Inc. | 2011-11-01 |
| Brain Connectivity in Neurodevelopmental Disorders in Response to Treatment (NCT01364818) | University of North Carolina, Chapel Hill | 2011-09-01 |
| Long-term, Safety, Tolerability and Efficacy Study of AFQ056 in Adult Patients With Fragile X Syndrome (NCT01348087) | Novartis Pharmaceuticals | 2011-08-01 |
| Efficacy and Safety Study of STX209 (Arbaclofen) for the Treatment of Social Withdrawal in Children With Fragile X Syndrome (NCT01325220) | Seaside Therapeutics, Inc. | 2011-06-01 |
| A Study to Assess the Tolerability of a Single Dose of STX107 in Adults With Fragile X Syndrome (NCT01325740) | Seaside Therapeutics, Inc. | 2011-05-01 |
| Efficacy and Safety Study of STX209 (Arbaclofen) for Social Withdrawal in Adolescents and Adults With Fragile X Syndrome (NCT01282268) | Seaside Therapeutics, Inc. | 2011-05-01 |
| Safety and Efficacy of AFQ056 in Adolescent Patients With Fragile X Syndrome (NCT01357239) | Novartis Pharmaceuticals | 2011-05-01 |
| Safety and Efficacy Study of Antioxidants for the Treatment of the Fragile X Syndrome (NCT01329770) | Yolanda de Diego Otero | 2010-12-01 |
| Safety and Efficacy of AFQ056 in Adult Patients With Fragile X Syndrome (NCT01253629) | Novartis Pharmaceuticals | 2010-11-01 |
| The Natural History of Reproductive and Overall Health in Girls and Women With a Pre-Mutation in the FMR1 Gene; Creation of a Patient Registry (NCT01187524) | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 2010-08-05 |
| Acamprosate in Youth With Fragile X Syndrome (NCT01300923) | Indiana University | 2010-08-01 |
| Trial of Minocycline to Treat Children With Fragile X Syndrome (NCT01053156) | University of California, Davis | 2010-01-01 |
| An Open Label Extension Study of STX209 in Subjects With Fragile X Syndrome (NCT01013480) | Seaside Therapeutics, Inc. | 2009-11-01 |
| A Study With RO4917523 in Patients With Fragile X Syndrome (NCT01015430) | Hoffmann-La Roche | 2009-11-01 |
| Randomized Controlled Study of Donepezil in Fragile X Syndrome (NCT01120626) | Stanford University | 2009-09-01 |
| A Single-Dose Study in Normal Volunteers to Assess the Safety, Tolerability and Pharmacokinetics of STX107 (NCT00965432) | Seaside Therapeutics, Inc. | 2009-09-01 |
| Biomarker and DNA Collection in Subjects Participating in Protocol 22003 (NCT00892580) | Seaside Therapeutics, Inc. | 2009-05-01 |
| Riluzole in Fragile X Syndrome (NCT00895752) | Indiana University | 2009-04-01 |
| A PET Brain Imaging Study of mGluR5 in Subjects With Neuropsychiatric Conditions (NCT00870974) | Institute for Neurodegenerative Disorders | 2009-03-01 |
| Biomarker Testing and DNA Collection in Subjects Participating in Protocol 22001 (NCT00823368) | Seaside Therapeutics, Inc. | 2009-01-01 |
| Safety, Tolerability and Efficacy Study of STX209 in Subjects With Fragile X Syndrome (NCT00788073) | Seaside Therapeutics, Inc. | 2008-11-01 |
| Teaching Math Skills to Individuals With Fragile X Syndrome (NCT01204151) | Stanford University | 2008-09-01 |
| Efficacy, Safety and Tolerability of AFQ056 in Fragile X Patients (NCT00718341) | Novartis | 2008-06-01 |
| Open Label Study Investigating Safety and Efficacy of NPL2009 50 mg - 150 mg on Prepulse Inhibition Tests and Continuous Performance Tasks, Adults With Fragile X Syndrome (NCT00637221) | Neuropharm | 2008-03-01 |
| Add-on Pilot Trial of Minocycline to Treat Fragile X Syndrome (NCT00858689) | FRAXA Research Foundation | 2007-10-01 |
| A Prospective Open-label Study of Aripiprazole in Fragile X Syndrome (NCT00420459) | Indiana University | 2007-04-01 |
| Double-blind Placebo Controlled Study of Oxytocin in Fragile X Syndrome (NCT01254045) | Stanford University | 2007-02-01 |
| Protein Synthesis in the Brain of Patients With Fragile X Syndrome (NCT00362843) | National Institute of Mental Health (NIMH) | 2006-08-22 |
| An Open-Label Trial of Donepezil in Fragile X Syndrome (NCT00220584) | Stanford University | 2005-07-01 |
| Aromatase Activity and Ovarian Growth Factors in African-American Versus Caucasian Women (NCT00334971) | Massachusetts General Hospital | 2004-09-01 |
| Effects of CX516 on Functioning in Fragile X Syndrome and Autism (NCT00054730) | RespireRx | 2002-06-01 |
| The Psychiatric and Cognitive Phenotypes in Velocardiofacial Syndrome (NCT00768820) | The Chaim Sheba Medical Center | 2001-05-01 |