| Evaluate the Effect of Obicetrapib in Patients With HeFH on Top of Maximum Tolerated Lipid-Modifying Therapies. (NCT05425745) | NewAmsterdam Pharma | 2022-07-25 |
| Equitable Implementation of Cascade Screening for Familial Hypercholesterolemia (NCT05430191) | Northwestern University | 2022-07-20 |
| Effect of Breastfeeding on Lipid Profile and Cardiovascular Risk Markers in Women With Familial Hypercholesterolemia (NCT05367310) | Oslo University Hospital | 2022-05-01 |
| A Study of the Efficacy and Safety of Enclitide Chloride (MK-0616 Oral PCSK9 Inhibitor) in Adults With Hypercholesterolemia (MK-0616-008) (NCT05261126) | Merck Sharp & Dohme LLC | 2022-03-10 |
| Coronary and Heart Effects of Early Treatment in Familial Hypercholesterolemia (NCT05352386) | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 2022-03-07 |
| Improving Diagnosis and Clinical Management of Familial Hypercholesterolemia Through Integrated Machine Learning, Implementation Science, and Behavioral Economics (NCT05746247) | University of Pennsylvania | 2022-03-01 |
| Unravelling the Impact of Diet on Cardiovascular Health in Heterozygous Familial Hypercholesterolemia. (NCT05181553) | Laval University | 2022-01-10 |
| Advancing Cardiac Care Unit-based Rapid Assessment and Treatment of hypErcholesterolemia (NCT05218005) | University of British Columbia | 2022-01-01 |
| Exosome-based Nanoplatform for Ldlr mRNA Delivery in FH (NCT05043181) | Tang-Du Hospital | 2021-12-01 |
| Advanced Lipoproptein Profiling and Cardiovascular Risk Stratification in Familial Hypercholesterolemia (NCT05066932) | Assistance Publique - Hôpitaux de Paris | 2021-10-20 |
| A Prospective Cohort Study on Familial Hypercholesterolemia in Health Examination Population (NCT04958629) | Peking University Third Hospital | 2021-10-01 |
| Pilot Study for a National Screening for Familial Hypercholesterolemia (NCT05271305) | Centre Hospitalier du Luxembourg | 2021-09-04 |
| Evaluation of a Digiphysical Screening Method to Identify and Diagnose Familial Hypercholesterolemia (NCT04929457) | Karolinska Institutet | 2021-09-01 |
| The Use of Mobile Health Technology and Behavioral Economics to Encourage Adherence in Adolescents (NCT04458766) | Boston Children's Hospital | 2021-01-01 |
| Long-term Efficacy and Safety of OLE LIB003 in HoFH, HeFH, and High-risk CVD Patients Requiring Further LDL-C Reduction (NCT04798430) | LIB Therapeutics LLC | 2020-12-03 |
| Pediatric Reporting of Adult-Onset Genomic Results (NCT03832985) | Geisinger Clinic | 2020-11-25 |
| Cascade Genetic Testing of Familial Hypercholesterolemia (NCT04419090) | Center for Primary Care and Public Health (Unisante), University of Lausanne, Switzerland | 2020-11-10 |
| Familial Hypercolerstremia as Risk Factor in Stemi Patient Who Underwent Ppci (NCT03900169) | Assiut University | 2020-11-01 |
| A Study to Determine the Safety, Tolerability, and Efficacy of SHR-1209 in Patients With Familial Hypercholesterolemia (NCT04455581) | Jiangsu HengRui Medicine Co., Ltd. | 2020-09-01 |
| Genetic Testing and Motivational Counseling for FH (NCT04656028) | National Medical Research Center for Therapy and Preventive Medicine | 2020-06-15 |
| Genetic Causes of Familial Hypercholesterolemia (NCT04101149) | Region Örebro County | 2019-09-01 |
| Study of ARO-ANG3 in Healthy Volunteers and in Dyslipidemic Patients (NCT03747224) | Arrowhead Pharmaceuticals | 2019-01-07 |
| Impact of LDL-cholesterol Lowering on Platelet Activation (NCT03331666) | Columbia University | 2018-11-16 |
| Alirocumab and Plaque Burden In Familial Hypercholesterolaemia (NCT05465278) | Fundación Hipercolesterolemia Familiar | 2018-05-01 |
| a Prospective Pilot Study of Screening Out Rate and Clinical Management of Familial Hypercholesterolemia (NCT03398954) | China Cardiovascular Association | 2018-01-18 |
| PMMHRI - Familial Hypercholesterolemia Registry (NCT06571630) | Polish Mother Memorial Hospital Research Institute | 2018-01-01 |
| IN-TANDEM Familial Hypercholesterolemia Pilot Study (NCT03253432) | University of Pennsylvania | 2017-07-20 |
| Aortic Stenosis in Subjects With Heterozygous Familial Hypercholesterolemia on Prolonged Treatment With Statins (NCT03310671) | Instituto Aragones de Ciencias de la Salud | 2017-07-18 |
| Improving Identification of Familial Hypercholesterolaemia in Primary Care (FAMCAT) (NCT03934320) | University of Nottingham | 2017-06-12 |
| An Extension Trial of Inclisiran in Participants With Cardiovascular Disease and High Cholesterol (NCT03060577) | Novartis Pharmaceuticals | 2017-04-27 |
| Familial Hypercholesterolemia in Turkey (A-HIT2) (NCT03110250) | Ege University | 2017-02-26 |
| Genetic Causes of Hypercholesterolaemia in the Emirati Population (NCT03597958) | Imperial College London Diabetes Centre | 2017-01-17 |
| Greek Registry - Familial Hypercholesterolaemia (NCT03140605) | Hellenic College of Treatment of Atherosclerosis | 2017-01-10 |
| Treatment Rates and Compliance to Treatment in Patients With Familial Hypercholesterolemia (NCT04494464) | Ankara Yildirim Beyazıt University | 2017-01-01 |
| Safety, Tolerability and Efficacy of Evolocumab (AMG 145) in Children With Inherited Elevated Low-density Lipoprotein Cholesterol (Familial Hypercholesterolemia) (NCT02624869) | Amgen | 2016-09-10 |
| Pediatric Population Screening for Type 1 Diabetes and Familial Hypercholesterolemia in Lower Saxony, Germany (NCT02750527) | Kinderkrankenhaus auf der Bult | 2016-09-01 |
| Developing and Implementing Familial Hypercholesterolemia Registry (NCT02865694) | Isfahan University of Medical Sciences | 2016-08-01 |
| Familial Hypercholesterolemia Amongst Patients With Acute Coronary Syndrome (NCT02870660) | Isfahan University of Medical Sciences | 2016-08-01 |
| Long Term Post Marketing Specified Drug Use Result Survey for Evolocumab in Japan (NCT02808403) | Amgen | 2016-06-24 |
| A Clinical Trial to Assess the Long Term Safety and Tolerability of MK-0653H in Japanese Participants With Hypercholesterolemia (MK-0653H-833) (NCT02748057) | Organon and Co | 2016-05-18 |
| Postprandial Response After Intake of Meals With Different Fatty Acid Composition (NCT02729857) | University of Oslo | 2016-03-01 |
| Return of Actionable Variants Empirical Study (NCT03640234) | Mayo Clinic | 2016-02-25 |
| Trial to Evaluate the Effect of ALN-PCSSC Treatment on Low Density Lipoprotein Cholesterol (LDL-C) (NCT02597127) | The Medicines Company | 2016-01-01 |
| Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of IONIS ANGPTL3-LRx in Healthy Volunteers With Elevated Triglycerides and Participants With Familial Hypercholesterolemia (NCT02709850) | Ionis Pharmaceuticals, Inc. | 2015-11-30 |
| Effects of LDL Apheresis System on the Expression of Genes Involved in Lipoprotein Metabolism and Inflammation in Homozygotes for Familial Hypercholesterolemia (NCT02462655) | Laval University | 2015-10-01 |
| Lipid Transport Disorder Italian Genetic Record (LIPIGEN) (NCT06362473) | Fondazione SISA (Societa Italiana per lo Studio della Arteriosclerosi) | 2015-08-04 |
| A Registration Study for Familial Hypercholesterolemia in Taiwan (NCT03152656) | National Taiwan University Hospital | 2015-07-01 |
| EAS Familial Hypercholesterolaemia Studies Collaboration (NCT04272697) | Imperial College London | 2015-03-22 |
| French Observatory of Familial Hypercholesterolemia in Cardiology (NCT02013713) | French Cardiology Society | 2014-11-01 |
| Atherosclerosis in Familial Hypercholesterolemia (NCT02489253) | University College, London | 2014-04-01 |
| Russian Familial Hypercholesterolemia Registry (NCT02208869) | Russian Cardiology Research and Production Center | 2014-01-01 |
| Relationships Between Plasma PCSK9 Levels, LDL-cholesterol Concentrations and Lipoprotein (a) Levels in Familial Hypercholesterolemia (NCT02225340) | Laval University | 2014-01-01 |
| Familial Hypercholesterolemia Canada / Hypercholesterolemie Familiale Canada (NCT02009345) | McGill University Health Centre/Research Institute of the McGill University Health Centre | 2013-11-01 |
| Early Detection of Familial Hypercholesterolemia in Children (NCT04370899) | Institut Investigacio Sanitaria Pere Virgili | 2013-03-14 |
| Cardiovascular Disease in FH Heterozygous (NCT01783405) | Sociedad Española de Arteriosclerosis | 2013-02-01 |
| Efficacy of a New Symbiotic Formulation in Children With Familial Hypercholesterolemia (NCT02048410) | Federico II University | 2012-01-01 |
| Effects of Low-density Lipoprotein (LDL) Apheresis on Inflammatory and Lipid Markers (NCT01138371) | Emory University | 2011-03-01 |
| Amlodipine/Atorvastatin (Caduet®) Drug Use Investigation (Regulatory Post Marketing Commitment Plan) (NCT01107743) | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 2010-06-01 |
| Long Term, Follow-on Study of Lomitapide in Patients With Homozygous Familial Hypercholesterolemia (NCT00943306) | Aegerion Pharmaceuticals, Inc. | 2009-10-29 |
| Soy Food Intervention Trial (NCT00924339) | Medical University of Vienna | 2009-09-01 |
| Atorvastatin Three Year Pediatric Study (NCT00827606) | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 2009-03-01 |
| Effect of Rapeseed Oil and Sunflower Oil (NCT00924274) | Medical University of Vienna | 2008-03-01 |
| A Study of the Safety and Efficacy of Patients With Familial Hypercholesterolaemia Taking Colesevelam as add-on Therapy to Their Existing Medication (NCT00655265) | Genzyme, a Sanofi Company | 2007-08-01 |
| A 52-week Post-marketing, Observational Study to Confirm the Safety and Efficacy of Zetia Alone or in Combination With Other Lipid-lowering Drugs in Japanese Subjects With Hypercholesterolemia (Study P05245) (NCT00705211) | Organon and Co | 2007-06-01 |
| A 12-week Post-marketing, Observational Study to Confirm the Safety and Efficacy of Zetia Alone or in Combination With Other Lipid-lowering Drugs in Japanese Subjects With Hypercholesterolemia (Study P05244) (NCT00704444) | Organon and Co | 2007-06-01 |
| Effect of APL180 on Endothelial Function in Familial Hypercholesterolemia Patients (NCT00751608) | Novartis Pharmaceuticals | 2006-09-01 |
| PLUTO: Pediatric Lipid-redUction Trial of rOsuvastatin (NCT00355615) | AstraZeneca | 2006-07-01 |
| Implitapide in Patients With Heterozygous Familial Hypercholesterolemia (HeFH) on Maximal Concurrent Lipid-Lowering Therapy (NCT00079859) | Medical Research Laboratories International | 2003-10-01 |
| Implitapide in Patients With Homozygous Familial Hypercholesterolemia (HoFH) on Maximal Concurrent Lipid-Lowering Therapy (NCT00079846) | Medical Research Laboratories International | 2003-09-01 |
| Detection of Familial Hypercholesterolaemia in Cardiovascular Disease Registry (NCT02778646) | University College, London | 2003-01-01 |
| Ezetimibe (SCH 58235) Taken With Either Atorvastatin or Simvastatin in Participants With Familial Hypercholesterolemia (MK-0653-018) (NCT03884452) | Organon and Co | 2000-05-03 |
| Low-Density Lipoprotein (LDL) Apheresis Using H.E.L.P. Therapy (NCT00916643) | B. Braun Medical Inc. | 1999-12-01 |