| A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma (NCT04978727) | Children's Oncology Group | 2022-07-01 |
| Individualized Treatment Plan in Children and Young Adults With Relapsed Medulloblastoma and Ependymoma (NCT05057702) | University of California, San Francisco | 2022-02-22 |
| Chemo-immunotherapy Using Ibrutinib Plus Indoximod for Patients With Pediatric Brain Cancer (NCT05106296) | Theodore S. Johnson | 2022-02-08 |
| A Study of Bempegaldesleukin (BEMPEG: NKTR-214) in Combination With Nivolumab in Children, Adolescents and Young Adults With Recurrent or Treatment-resistant Cancer (NCT04730349) | Bristol-Myers Squibb | 2021-06-03 |
| Brain Tumor-Specific Immune Cells (IL13Ralpha2-CAR T Cells) for the Treatment of Leptomeningeal Glioblastoma, Ependymoma, or Medulloblastoma (NCT04661384) | City of Hope Medical Center | 2021-03-05 |
| Phase I Study of Oral ONC206 in Recurrent and Rare Primary Central Nervous System Neoplasms (NCT04541082) | Jazz Pharmaceuticals | 2020-10-26 |
| Innovative Trial for Understanding the Impact of Targeted Therapies in NF2-Related Schwannomatosis (INTUITT-NF2) (NCT04374305) | Scott R. Plotkin, MD, PhD | 2020-06-20 |
| Marizomib for Recurrent Low-Grade and Anaplastic Supratentorial, Infratentorial, and Spinal Cord Ependymoma (NCT03727841) | National Cancer Institute (NCI) | 2020-01-22 |
| Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors (NCT04185038) | Seattle Children's Hospital | 2019-12-11 |
| Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG (NCT04049669) | Theodore S. Johnson | 2019-10-02 |
| Social Determinants of Health in Glioblastoma Population (NCT03900689) | Wake Forest University Health Sciences | 2019-05-22 |
| LET Optimized IMPT in Treating Pediatric Patients With Ependymoma (NCT03750513) | M.D. Anderson Cancer Center | 2019-04-01 |
| EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors (NCT03638167) | Seattle Children's Hospital | 2019-03-19 |
| HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors (NCT03500991) | Seattle Children's Hospital | 2018-07-26 |
| SJDAWN: St. Jude Children's Research Hospital Phase 1 Study Evaluating Molecularly-Driven Doublet Therapies for Children and Young Adults With Recurrent Brain Tumors (NCT03434262) | St. Jude Children's Research Hospital | 2018-03-05 |
| Proton Therapy Research Infrastructure- ProTRAIT- Neuro-oncology (NCT04648462) | Maastricht Radiation Oncology | 2018-01-01 |
| Vemurafenib in Treating Patients With Relapsed or Refractory Advanced Solid Tumors, Non-Hodgkin Lymphoma, or Histiocytic Disorders With BRAF V600 Mutations (A Pediatric MATCH Treatment Trial) (NCT03220035) | National Cancer Institute (NCI) | 2017-11-08 |
| Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors (NCT03194906) | St. Jude Children's Research Hospital | 2017-11-07 |
| Phase 1b Study PVSRIPO for Recurrent Malignant Glioma in Children (NCT03043391) | Istari Oncology, Inc. | 2017-11-07 |
| Rare CNS Tumors Outcomes &Risk (NCT03251989) | National Cancer Institute (NCI) | 2017-08-21 |
| A Study of the Treatment of Recurrent Malignant Glioma With rQNestin34.5v.2 (NCT03152318) | Dana-Farber Cancer Institute | 2017-07-18 |
| Immune Checkpoint Inhibitor Nivolumab in People With Recurrent Select Rare CNS Cancers (NCT03173950) | National Cancer Institute (NCI) | 2017-07-13 |
| Trial of Selumetinib in Patients With Neurofibromatosis Type II Related Tumors (NCT03095248) | Children's Hospital Medical Center, Cincinnati | 2017-05-08 |
| HUMC 1612: Optune NovoTTF-200A System (NCT03128047) | Hackensack Meridian Health | 2017-04-06 |
| Optune for Children With High-Grade Glioma or Ependymoma, and Optune With Radiation Therapy for Children With DIPG (NCT03033992) | Children's Oncology Group | 2017-04-04 |
| Autologous Stem Cell Collection and Reinfusion in Newly Diagnosed High Grade Gliomas (NCT02976441) | Washington University School of Medicine | 2017-01-01 |
| Erlotinib in Combination With Temozolomide in Treating Relapsed/Recurrent/Refractory Pediatric Solid Tumors (NCT02689336) | Washington University School of Medicine | 2016-08-06 |
| Trial of Heat Shock Protein Peptide Complex-96 (HSPPC-96) Vaccine (NCT02722512) | Ann & Robert H Lurie Children's Hospital of Chicago | 2016-07-01 |
| Study of the IDO Pathway Inhibitor, Indoximod, and Temozolomide for Pediatric Patients With Progressive Primary Malignant Brain Tumors (NCT02502708) | NewLink Genetics Corporation | 2015-10-01 |
| A Trial of Surgery and Fractionated Re-Irradiation for Recurrent Ependymoma (NCT02125786) | St. Jude Children's Research Hospital | 2014-05-07 |
| Study of SBRT Efficacy on Intra and Extra -Cranial Tumors or Metastasis in Pediatrics Population (SBRT Pediatrics) (NCT02013297) | Centre Leon Berard | 2013-12-03 |
| Imetelstat Sodium in Treating Younger Patients With Recurrent or Refractory Brain Tumors (NCT01836549) | Pediatric Brain Tumor Consortium | 2013-03-01 |
| Phase I Study of 5-Fluorouracil in Children and Young Adults With Recurrent Ependymoma (NCT01498783) | St. Jude Children's Research Hospital | 2011-12-01 |
| Single-agent Erlotinib in Patients Previously Treated With Oral Etoposide in Protocol OSI-774-205 (NCT01247922) | OSI Pharmaceuticals | 2011-05-23 |
| Carboplatin and Bevacizumab for Recurrent Ependymoma (NCT01295944) | National Cancer Institute (NCI) | 2011-04-27 |
| Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors (NCT01331135) | Emory University | 2011-04-01 |
| Proton Radiotherapy for Pediatric Brain Tumors Requiring Partial Brain Irradiation (NCT01288235) | Massachusetts General Hospital | 2011-02-01 |
| Multicenter Register for Children and Young Adults With Intracranial Localized Medulloblastoma, CNS-PNET or Ependymoma (NCT02238899) | Universitätsklinikum Hamburg-Eppendorf | 2011-01-01 |
| Vaccination With Dendritic Cells Loaded With Brain Tumor Stem Cells for Progressive Malignant Brain Tumor (NCT01171469) | Masonic Cancer Center, University of Minnesota | 2010-09-01 |
| Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Ependymoma (NCT01096368) | Children's Oncology Group | 2010-05-07 |
| A Pilot Study Evaluating 18F-L-Thymidine (FLT) PET Imaging in Children With Gliomas (NCT01117155) | National Cancer Institute (NCI) | 2010-04-23 |
| Carboplatin as a Radiosensitizer in Treating Childhood Ependymoma (NCT01088035) | Ann & Robert H Lurie Children's Hospital of Chicago | 2010-04-01 |
| A Phase I Study of ABT-888, an Oral Inhibitor of Poly(ADP-ribose) Polymerase and Temozolomide in Children With Recurrent/Refractory CNS Tumors (NCT00994071) | National Cancer Institute (NCI) | 2009-09-22 |
| Methionine PET/CT Studies In Patients With Cancer (NCT00840047) | St. Jude Children's Research Hospital | 2009-07-20 |
| A Study of Pemetrexed in Children With Recurrent Cancer (NCT00520936) | Eli Lilly and Company | 2007-09-01 |
| Exploratory Study of Effects of Radiation Therapy in Pediatric Patients With Central Nervous System Tumors (NCT01445288) | National Cancer Institute (NCI) | 2006-12-05 |
| Collecting and Storing Blood and Brain Tumor Tissue Samples From Children With Brain Tumors (NCT00919750) | Children's Oncology Group | 2004-02-16 |
| Antineoplaston Therapy in Treating Patients With Ependymoma (NCT00003479) | Burzynski Research Institute | 1966-07-01 |