| Functional Lung Imaging in Patients With Respiratory Compromise Undergoing Endobronchial Valve Placement (NCT05204875) | Temple University | 2022-07-05 |
| A Multicenter, Prospective Trial of the IAB in Adults Suffering From COPD/Emphysema (NCT05087641) | Pulmair Medical, Inc. | 2022-05-03 |
| Pulmonary and Cardiac Effects of E-Cigarette Use in Pulmonary Patients Who Smoke Cigarettes (NCT05610514) | University of Vermont | 2022-04-28 |
| Study on the Influence of Climatic and Environmental Factors on Respiratory Diseases in Sanya, Hainan Province, China. (NCT05330637) | Shanghai Jiao Tong University School of Medicine | 2022-03-03 |
| Evaluation of Immunological, Microbiological and Metabolomic Profiles in COPD (NCT06826560) | Medical University of Warsaw | 2022-03-01 |
| Global Utilization And Registry Database for Improved preservAtion of doNor LUNGs (NCT04930289) | Paragonix Technologies | 2021-10-15 |
| STRIVE Post-Market Registry Study (NCT04302272) | Olympus Corporation of the Americas | 2021-10-09 |
| Effect of EPAP Device on Emphysema and Lung Bullae (NCT04742114) | Qilu Hospital of Shandong University | 2021-07-31 |
| The Lung Microbiome and Endobronchial Valve Treatment (NCT04932811) | Aarhus University Hospital | 2021-06-16 |
| Mind The Gap - Crossing Borders Study (NCT04256408) | University Medical Center Groningen | 2021-06-01 |
| 4D Medical X-ray Velocimetry for Bronchoscopic Lung Volume Reduction Targeting (NCT04786171) | Vanderbilt University Medical Center | 2021-01-07 |
| Developing Optimal Parameters for Hyperpolarized Noble Gas and Inert Fluorinated Gas MRI of Lung Disorders (NCT02748798) | Thunder Bay Regional Health Research Institute | 2020-11-10 |
| Lung Damage Caused by SARS-CoV-2 Pneumonia (COVID-19) (NCT04435327) | University of Milano Bicocca | 2020-10-05 |
| Surgical Compared to Bronchoscopic Lung Volume Reduction in Patients With Severe Emphysema (NCT04537182) | Isabelle Opitz, Professor, MD | 2020-09-01 |
| Kingston Chronic Obstructive Pulmonary Disease (COPD) Multidimensional Long Term Follow up Cohort (NCT04200079) | Dr. Juan Pablo de Torres Tajes | 2020-01-14 |
| Feasibility of a Multi Component Intervention in Patients With Severe Dyspnea and Obesity (NCT03836547) | Mayo Clinic | 2019-12-19 |
| Zephyr Valve Registry (ZEVR) (NCT04186546) | Pulmonx Corporation | 2019-11-25 |
| Cinenses Lung Volume Reduction Reverser System First-in-man Study Treating Patients With Severe Emphysema (NCT03685526) | Lifetech Scientific (Shenzhen) Co., Ltd. | 2019-05-06 |
| Mortality and Symptom Burden Post Hospitalisation With COPD (NCT03657121) | Northumbria Healthcare NHS Foundation Trust | 2019-01-16 |
| Hyperinflation Assessment After Treatment by Lung Volume Reduction Coil (NCT02835001) | University Hospital, Toulouse | 2019-01-15 |
| Home Pulmonary Rehabilitation for COPD (NCT03480386) | Mayo Clinic | 2019-01-01 |
| A Home-based Intervention to Promote Mindful Breathing Awareness Through Pursed-lip Breathing Training for COPD Patients (NCT03814980) | Mayo Clinic | 2018-11-01 |
| A 12-week Study Treating Participants Who Have alpha1-antitrypsin-related COPD With Alvelestat (MPH966) or Placebo. (NCT03636347) | Mereo BioPharma | 2018-10-29 |
| Belimumab Treatment of Emphysema Patients With Anti-GRP78 Autoantibodies (NCT03244059) | University of Alabama at Birmingham | 2018-08-09 |
| A Trial on the Effects of Bronchoscopic Lung Volume Reduction in Severe Emphysema. (NCT03474471) | University Medical Center Groningen | 2018-07-31 |
| Mechanistic Effects of Health Coaching to Reduce Chronic Obstructive Pulmonary Disease (COPD) Hospitalizations (NCT03837847) | Mayo Clinic | 2018-07-05 |
| Melodica Orchestra for Dyspnea: Safety and Feasibility Pilot (NCT03653104) | VA Quality Enhancement Research Intiative | 2018-06-12 |
| Comparison of the Effectiveness of Home and Hospital-based PR in Candidate Patients With BLVR (NCT03518177) | Istanbul Medipol University Hospital | 2018-05-15 |
| Study of PneumRx Endobronchial Coil System in Treatment of Subjects With Severe Emphysema (NCT03360396) | Boston Scientific Corporation | 2018-05-07 |
| Exploring the Utility of Hyperpolarized 129Xe MRI in Healthy Volunteers and Patients With Lung Disease (NCT03455686) | McMaster University | 2018-04-19 |
| Smoking Cessation and Functional CT Assessment (NCT03382106) | Eric A. Hoffman | 2018-03-19 |
| Evaluating the Clinical Effectiveness of 3D Printing for a Patient-specific Silicone Stent Airway Implant (NCT03111888) | The Cleveland Clinic | 2017-10-01 |
| LVR in Severe Emphysema Using Bronchoscopic Autologous Blood Instillation in Combination With Intra-bronchial Valves (NCT03010449) | Royal Brompton & Harefield NHS Foundation Trust | 2017-08-24 |
| Functional CT Assessment of Pulmonary Arterial Dysfunction in Smoking Associated Emphysema (NCT02682147) | Eric A. Hoffman | 2017-07-10 |
| Implementing and Evaluating the Genie Tool in COPD (NCT02935452) | University of Southampton | 2017-06-08 |
| Losartan Effects on Emphysema Progression (NCT02696564) | JHSPH Center for Clinical Trials | 2017-05-23 |
| Efficacy/Safety of HA Inhalation Solution for Hereditary Emphysema in Patients With Alpha-1 Antitrypsin Deficiency (NCT03114020) | Gerard Turino | 2017-03-22 |
| Studying the Airway Microenvironment in Patients Undergoing Surgical and Bronchoscopic Interventions for COPD (NCT03010592) | Royal Brompton & Harefield NHS Foundation Trust | 2017-02-06 |
| BROnchoalveolar Investigations of Never-smokers With Chronic Obstruction From the Swedish CardioPulmonary bioImage Study (NCT03049202) | Karolinska Institutet | 2017-02-01 |
| Lung Volume Reduction Coil Microbiome Study (NCT03010566) | Royal Brompton & Harefield NHS Foundation Trust | 2017-01-30 |
| Targeting Pulmonary Perfusion in Alpha-1 Antitrypsin Deficiency (NCT03008915) | Columbia University | 2017-01-01 |
| Site and Mechanism(s) of Expiratory Airflow Limitation in COPD, Emphysema and Asthma-COPD Overlap (NCT03263130) | Gelb, Arthur F., M.D. | 2017-01-01 |
| Clinical Investigation of a Modified Staged Treatment Algorithm Using the AeriSeal System (NCT02877459) | Pulmonx Corporation | 2016-11-01 |
| Endoscopic Lung Volume Reduction Coil Treatment in Patients With Chronic Hypercapnic Respiratory Failure (NCT02996149) | Universitätsklinikum Hamburg-Eppendorf | 2016-11-01 |
| The Relationship Between GOLD Risk Group and Clinical Outcomes in a Community-based COPD Cohort (NCT02838108) | Duke University | 2016-10-01 |
| Advancing Symptom Alleviation With Palliative Treatment (NCT02713347) | VA Office of Research and Development | 2016-09-01 |
| REACH SVS Control Patient Cross-Over Study (NCT02914340) | Olympus Corporation of the Americas | 2016-09-01 |
| SCCOR Minorities Observational Study (NCT02898272) | University of Pittsburgh | 2016-08-01 |
| Activity Monitor Use in COPD Patients Undergoing Rehabilitation (NCT02895152) | Northern Care Alliance NHS Foundation Trust | 2016-08-01 |
| Endobronchial Valve in Patients With Heterogeneous Emphysema (NCT02823223) | Chinese PLA General Hospital | 2016-06-01 |
| Prevalence of Sleep Disordered Breathing in a Lung Cancer Screening Cohort (NCT02687997) | Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz | 2016-02-01 |
| Computed Tomography Assessment of Regional Ventilation (CURVE) (NCT02879773) | Heart of England NHS Trust | 2016-01-22 |
| The Effect of Physical Activity Promotion on Short and Long-term Outcomes in COPD (NCT02099799) | VA Office of Research and Development | 2015-11-17 |
| A Prospective Multicenter Clinical Study to Evaluate the Safety and Effectiveness of the OL-BF-001 for Severe Emphysema (NCT02470052) | Olympus Corporation | 2015-08-01 |
| Changes in Lung Physiology and Cardiac Performance in Patients With Emphysema Post Bilateral RePneu Coil Treatment (NCT02499380) | Boston Scientific Corporation | 2015-06-09 |
| Spiration Valve System 9 mm European Post Market Evaluation Study (NCT03008226) | Heidelberg University | 2015-06-01 |
| Genetics of the Combined Pulmonary Fibrosis and Emphysema Syndrome (NCT02439528) | Hospices Civils de Lyon | 2015-03-25 |
| Alpha-1 Carrier Genomics Study (NCT02810327) | Medical University of South Carolina | 2015-02-01 |
| Doxycycline for COPD in HIV-Infected Patients (NCT01744093) | Weill Medical College of Cornell University | 2014-12-08 |
| Lung Volume Reduction Coils for Emphysema in Alpha-1 Antitrypsin Deficiency (NCT02273349) | University Hospital, Saarland | 2014-10-01 |
| Electrical Impedance Imaging of Patients on Mechanical Ventilation (NCT02232841) | Colorado State University | 2014-09-01 |
| Longitudinal Evaluation of HIV-associated Lung Disease Phenotypes (NCT02238327) | University of Pittsburgh | 2014-09-01 |
| COPD Patient-Powered Research Network (NCT02803242) | COPD Foundation | 2014-08-01 |
| Assessment of Emphysema Using 1.5T MRI With UTE Pulse Sequences (NCT02100800) | University Hospital, Bordeaux | 2014-05-23 |
| Mindfulness-based Cognitive Therapy for Chronic Obstructive Pulmonary Disease (NCT02042976) | University of Aarhus | 2014-02-01 |
| HIV+ Alveolar Macrophage Oxidant-mediated Apoptosis of Pulmonary Endothelium (NCT02056158) | Weill Medical College of Cornell University | 2014-01-13 |
| Prostaglandin Inhibition for Emphysema (NCT02006576) | University of Nebraska | 2014-01-01 |
| A Safety and Feasibility Study of Re-treating Patients With Severe Emphysema With the RePneu LVRC System. (NCT02012673) | University Medical Center Groningen | 2014-01-01 |
| LVRC IDE Crossover Study (Crossover From IDE Trial CLN0009) (NCT02059057) | Boston Scientific Corporation | 2013-12-01 |
| Safety and Clinical Outcomes Study: SVF Deployment for Orthopedic, Neurologic, Urologic, and Cardio-pulmonary Conditions (NCT01953523) | Elliot Lander | 2013-09-02 |
| Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability (NCT01615484) | University of North Carolina, Chapel Hill | 2013-09-01 |
| Study of the AeriSeal System Treatment in Patients With Advanced Non-Upper Lobe Predominant Heterogeneous Emphysema (NCT01908933) | Aeris Therapeutics | 2013-09-01 |
| Pulmonx Endobronchial Valves Used in Treatment of Emphysema (LIBERATE Study) (NCT01796392) | Pulmonx Corporation | 2013-07-01 |
| Evaluation of the Spiration® Valve System for Emphysema to Improve Lung Function (NCT01812447) | Olympus Corporation of the Americas | 2013-06-01 |
| Sequential Segmental Treatment of Emphysema With Upper Lobe Predominance (STEP-UP) Study (NCT01719263) | Uptake Medical Corp | 2013-06-01 |
| Post Market Observational, Prospective, Multi-center Study (NCT01806636) | Boston Scientific Corporation | 2013-05-01 |
| The Effectiveness of Roflumilast in Improving Mucociliary Clearance in Patients With COPD and Chronic Bronchitis (NCT03073798) | Johns Hopkins University | 2013-03-18 |
| Lung Volume Reduction Coil Treatment in Emphysema. (NCT01822795) | CHU de Reims | 2013-03-01 |
| Lung Volume Reduction for Severe Emphysema by Stereotactic Ablative Radiation Therapy (NCT03673176) | Stanford University | 2013-02-11 |
| Bronchoscopic Thermal Saline Ablation (BTSA) of Emphysematous Lung. A New Emphysema Therapy (NCT01920321) | Assaf-Harofeh Medical Center | 2013-02-01 |
| The Effect of Pulmonary Rehabilitation on Bronchoscopic Volume Reduction Process Success (NCT04347044) | Istanbul Medipol University Hospital | 2013-01-01 |
| Safety Study of Endobronchial Transplantation of Autologous Mesenchymal Stem Cells (MSCs) in Emphysema Patients (NCT01758055) | Arda Kiani | 2012-12-01 |
| Lung Volume Reduction Coil Treatment in Patients With Emphysema (RENEW) Study (NCT01608490) | Boston Scientific Corporation | 2012-10-01 |
| Imaging Lung Function Using Oxygen Enhanced MRI (NCT01731015) | Hal C Charles | 2012-01-01 |
| A Study of the Use of Chartis System to Optimize Subject Selection for Endobronchial Lung Volume Reduction (ELVR) (NCT01101958) | Pulmonx Corporation | 2012-01-01 |
| Evaluate the Effects of Formoterol and Beclomethasone Dipropionate Combination Therapy on Small Airways Function (NCT01466712) | KU Leuven | 2011-11-01 |
| Blood, Hair and Lung Concentrations of Metals and Metalloids in Patients With Lung Cancer or Chronic Obstructive Pulmonary Disease (NCT01949181) | Hopital Foch | 2011-08-01 |
| Hypoxic Pulmonary Vasoconstriction Pilot Study (NCT03733470) | Eric A. Hoffman | 2011-06-29 |
| A Study to Evaluate the Integrated Dose Counter on an Albuterol Hydrofluoroalkane (HFA) Metered Dose Inhaler (MDI) (NCT01302587) | Teva Branded Pharmaceutical Products R&D, Inc. | 2011-03-01 |
| Effect of Symbicort on Sleep Quality in Patients With Emphysema (NCT01602523) | Temple University | 2011-03-01 |
| A Registry Study of the AeriSeal® System or Lung Volume Reduction in Patients With Advanced Emphysema (NCT01449175) | Aeris Therapeutics | 2011-01-01 |
| Eccentric Exercise Training as Novel Rehabilitation for Chronic Obstructive Pulmonary Disease (COPD) (NCT01077102) | McGill University Health Centre/Research Institute of the McGill University Health Centre | 2011-01-01 |
| Effects of Exercise Training on Systemic Inflammation an Muscle Repair According to the Obstructive Chronic Pulmonary Disease (COPD) Phenotype (NCT01431625) | Hospitales Universitarios Virgen del Rocío | 2011-01-01 |
| Phase 2 Study of Ex-vivo Perfusion and Ventilation of Lungs to Assess Transplant Suitability (NCT01241942) | University of North Carolina, Chapel Hill | 2010-12-01 |
| Study of COPD Subgroups and Biomarkers (NCT01969344) | University of North Carolina, Chapel Hill | 2010-11-01 |
| Safety and Pharmacokinetics of Alpha-1 Proteinase Inhibitor in Subjects With Alpha1-Antitrypsin Deficiency (NCT01213043) | Grifols Therapeutics LLC | 2010-11-01 |
| Safety and Feasibility Study of Administration of Mesenchymal Stemcells for Treatment of Emphysema (NCT01306513) | Leiden University Medical Center | 2010-10-01 |
| Prognostic Indicators as Provided by the EPIC ClearView (NCT01476995) | Epic Research & Diagnostics, Inc. | 2010-09-01 |
| Study on Phenotypic Characterization of Combined Pulmonary Fibrosis and Emphysema (NCT01121367) | Beijing Chao Yang Hospital | 2010-05-01 |
| Randomized Comparison of the RePneu Lung Volume Reduction Coil (LVRC) to Standard of Care for the Treatment of Emphysema (RESET Study) (NCT01334307) | Boston Scientific Corporation | 2010-02-01 |