| Randomised Research Comparing Acupuncture, Herbal Treatment and Artificial Tear Eye Drops in Dry Eye (NCT02219204) | Singapore National Eye Centre | 2015-03-01 |
| OTX-14-006: A Phase 2 Study Evaluating the Safety and Efficacy of OTX-DP for the Treatment of Dry Eye (NCT02468700) | Ocular Therapeutix, Inc. | 2015-01-01 |
| Topical Cyclosporine A for the Treatment of Dry Eye: A Randomized Clinical Study (NCT04714099) | Alexandria University | 2015-01-01 |
| Evaluation of Meibomian Gland Dysfunction in Chinese Old Patients (NCT02481167) | Wenzhou Medical University | 2015-01-01 |
| Platelet -Rich Plasma (PRP) Injection for the Treatment of Severe Dry Eye (NCT02257957) | Universidad Nacional de Colombia | 2014-11-30 |
| Dry Eye Assessment and Management Study (NCT02128763) | University of Pennsylvania | 2014-11-01 |
| Efficacy and Safety of XG-104 for the Treatment of Dry Eye (NCT02235259) | Xigen SA | 2014-09-01 |
| Topical Steroid Treatment For Dry Eye (NCT02218827) | Meir Medical Center | 2014-09-01 |
| DNase Treatment for Dry Eyes (NCT02193490) | University of Illinois at Chicago | 2014-07-01 |
| Ocular Surface Microbiome in Dry Eye Patients (NCT02161341) | Singapore National Eye Centre | 2014-06-01 |
| Tear Proteins, Conjunctival Cells and Imaging Eyes in Rheumatoid Arthritis and Systemic Lupus Erythematosus Patients (NCT02217137) | Singapore National Eye Centre | 2014-06-01 |
| Civamide Nasal Solution for the Treatment of Dry Eye (NCT02116244) | Winston Laboratories | 2014-05-01 |
| Multi-Colored Placido Disk Viability (NCT02148497) | University of Rochester | 2014-05-01 |
| Treatment of Meibomian Gland Dysfunction and Dry Eye in Contact Lens Wearers (NCT02102464) | TearScience, Inc. | 2014-04-01 |
| The Effects of Cyclosporin A in a Low Humidity Environment, on the Ocular Surface (NCT02199964) | Baylor College of Medicine | 2014-03-01 |
| The Role of Cytokines and Mast Cell in the Pathogenesis of SLK, Conjunctivochalasis, and Dry Eye (NCT02160327) | National Taiwan University Hospital | 2014-03-01 |
| Clinical Outcomes Following Treatment With Systane® Balance in Dry Eye Subjects (NCT01967147) | Alcon Research | 2014-02-01 |
| Efficacy and Safety of Fluorometholone (FML) in Dry Eye Disease (Keratoconjunctivitis Sicca) (NCT02051023) | Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA | 2014-02-01 |
| Tear Layer Lipid Thickness in Pterygium Patient Before and After Surgery (NCT02160769) | Singapore National Eye Centre | 2013-11-01 |
| Efficacy and Safety of PRO-148 Versus Systane®, in Patients With Mild to Moderate Dry Eye (NCT01657253) | Laboratorios Sophia S.A de C.V. | 2013-11-01 |
| Efficacy of Topical 0.2% Xanthan Gum in Patients With Dry Eye (NCT01959854) | SIFI SpA | 2013-09-01 |
| The Retention Rate Between Brand A and Brand B Punctal Plugs (NCT01947517) | Queen's University | 2013-09-01 |
| Effects of Gunnar Computer Glasses on Viewing Comfort and Performance (NCT02925884) | Pacific University | 2013-06-01 |
| Mucin Levels in Dry Eye and Normal Populations (NCT05911555) | ORA, Inc. | 2013-05-01 |
| Efficacy and Safety Study of FID 119515A (NCT01833117) | Alcon Research | 2013-05-01 |
| A Study to Evaluate the Performance and Safety of Artelac Rebalance® Versus Vismed in the Management of Dry Eye (NCT01791426) | Bausch & Lomb Incorporated | 2013-05-01 |
| A Phase 1/2, RU-101 Ophthalmic Solution in Patients With Severe Dry Eye (NCT01843894) | R-Tech Ueno, Ltd. | 2013-04-01 |
| Phase 1 Study for Safety and Tolerability of EBI-005 Topically Administered to Eyes of Healthy Adult Subjects (NCT01748578) | Eleven Biotherapeutics | 2012-11-01 |
| Safety and Efficacy of Punctal Plug Insertion in Patients With Dry Eye (NCT01684436) | Allergan | 2012-10-01 |
| Determination of Cell Population in Solution-Induced Corneal Staining (SICS) and Symptomatic Versus Asymptomatic Lens Wearers (NCT01629706) | CIBA VISION | 2012-09-01 |
| The Effect of SYSTANE® BALANCE on Tear Film Break Up Time in Dry Eye Subjects (NCT01718028) | Alcon Research | 2012-09-01 |
| Confirmatory Study of OPC-12759 Ophthalmic Solution (NCT01660256) | Otsuka Pharmaceutical Co., Ltd. | 2012-08-01 |
| Visual Quality Change of Eyes Implanted With Diffractive Multifocal Intraocular Lens After Cataract Surgery (NCT02234635) | Wenzhou Medical University | 2012-08-01 |
| The Effect of Electrical Stimulation on Tear Production (NCT01630291) | Oculeve, Inc. | 2012-07-01 |
| Tear Osmolarity Changes After Instilling Isotonic Hyaluronate Artificial Tears (NCT01614847) | Thomas O Salmon, OD, PhD | 2012-06-01 |
| Patient Satisfaction and Tear Osmolarity With the Use of Blink Tears, Blink Gel Tears and Systane Balance (NCT01589640) | Ophthalmic Consultants of Connecticut | 2012-05-01 |
| Dry Eye Evaluation After Transepithelial PRK (NCT02210793) | AL-Nour Eye Hospital | 2012-04-01 |
| Optimization of Assessment and Grading for Lid Wiper Epitheliopathy (NCT01611922) | Alcon Research | 2012-04-01 |
| Randomized Controlled Trial of Long-term Treatment Effectiveness for Meibomian Gland Dysfunction (MGD) and Dry Eye (NCT01521507) | TearScience, Inc. | 2012-01-01 |
| Safety, Tolerability and Pharmacokinetics of 0.5% and 2.5% Cis-UCA Eye Drops in Adult Healthy Volunteers (Phase I) (NCT01476332) | Laurantis Pharma, Ltd. | 2011-11-01 |
| The Effect of Hinge Location on Corneal Sensation and Dry Eye After LASIK: A Systematic Review and Meta-analysis (NCT01507025) | Yifan Feng | 2011-10-01 |
| Corneal Sensation and Incidence of Dry Eye Post Refractive Cataract Extraction With FemtoSecond Laser (NCT01441895) | Ophthalmic Consultants of Long Island | 2011-09-01 |
| Safety and Efficacy of Thymosin Beta 4 Ophthalmic Solution in Patients With Dry Eye (NCT01387347) | ReGenTree, LLC | 2011-08-01 |
| Tear Dynamics After Restasis Treatment in Dry Eye Patients (NCT00706940) | University of Miami | 2011-08-01 |
| Comparative Efficacy of SYSTANE® ULTRA vs Optive™ in Improving Tear Film Break-up Time (NCT01417013) | Alcon Research | 2011-07-01 |
| Efficacy of FreshKote and Systane for the Treatment of Dry Eye and Improvement of Osmolarity (NCT01386073) | Innovative Medical | 2011-07-01 |
| Moisture Chamber Glasses for Dry Eye in Asian Population (NCT01388426) | Singapore National Eye Centre | 2011-07-01 |
| Study to Evaluate the Ocular Tolerance of SYL1001 in Healthy Volunteers (NCT01438281) | Sylentis, S.A. | 2011-07-01 |
| Hydroxychloroquine Treatment of Dry Eyes in Patients With Primary Sjögren's Syndrome (NCT01601028) | Seoul National University Hospital | 2011-07-01 |
| Efficacy of the Chronic Application of Tear Formulations (NCT01384851) | Glasgow Caledonian University | 2011-07-01 |
| Objective Evaluation of Ocular Surface Lubricants in Two Environments (NCT01375582) | University of Rochester | 2011-06-01 |
| Comparison of Tolerability and Clinical Performance of Two Emulsion-type Artificial Tears (NCT01335126) | Hom, Milton M., OD, FAAO | 2011-03-01 |
| Evaluation of Extended Tear Film Break Up Time (TFBUT) With an Ocular Emulsion (NCT01368198) | Alcon Research | 2011-03-01 |
| A Clinical Evaluation of an Investigational Lubricant Eye Gel (FID 115958D) (NCT01294956) | Alcon Research | 2011-01-01 |
| The Effects of a Single Intravenous Administration of Secukinumab (AIN457) or Canakinumab (ACZ885) in Dry Eye Patients (NCT01250171) | Novartis Pharmaceuticals | 2010-11-01 |
| Safety and Efficacy Study of MIM-D3 Ophthalmic Solution for the Treatment of Dry Eye (NCT01257607) | Mimetogen Pharmaceuticals USA, Inc. | 2010-11-01 |
| RPS InflammaDry Detector™ to Determine MMP-9 Levels in Tears (NCT01313351) | Rapid Pathogen Screening | 2010-11-01 |
| Safety and Efficacy Study of DE-110 Ophthalmic Suspension for the Treatment of Dry Eye Disease (NCT01239069) | Santen Inc. | 2010-11-01 |
| Tear Osmolarity Over Time With Artificial Tears (NCT01227226) | Hom, Milton M., OD, FAAO | 2010-10-01 |
| Study to Evaluate a Contact Lens Lubricating and Rewetting Drop (NCT01267656) | Bausch & Lomb Incorporated | 2010-10-01 |
| Diurnal Variation of Tear Meniscus and Tear Osmolarity (NCT01206244) | University of Miami | 2010-09-01 |
| Efficacy Evaluation of SYSTANE® ULTRA in Patients Scheduled for Cataract Surgery (NCT01199510) | Alcon Research | 2010-09-01 |
| To Evaluate the Physical Effects of Systane(R) Lubricant Eye Drops Compared to Refresh Tears(R) Lubricant Eye Drops (NCT01160133) | Alcon Research | 2010-07-01 |
| Efficacy of Systane Balance to Stabilize the Tear Film in Dry Eye Subjects (NCT01086774) | Alcon Research | 2010-07-01 |
| An Evaluation of the Nighttime Retention of Effect of an Investigational Lubricant Eye Drop (FID 115958D) (NCT01165164) | Alcon Research | 2010-06-01 |
| Safety and Efficacy Study of EGP-437 (Dexamethasone Phosphate Formulated for Ocular Iontophoresis) to Treat Dry Eye (NCT01129856) | Eyegate Pharmaceuticals, Inc. | 2010-06-01 |
| An Evaluation of the Daytime Use of an Investigational Lubricant Eye Drop (NCT01139372) | Alcon Research | 2010-05-01 |
| Effects of Cataract Extraction Surgery and Limbal Relaxing Incision on Corneal Sensation and Dry Eye (NCT01161771) | Allergan | 2010-05-01 |
| Study Assessing Safety and Efficacy of DE-101 Ophthalmic Suspension in Dry Eye Patients (NCT01118754) | Santen Inc. | 2010-04-01 |
| Safety and Efficacy Study of Rebamipide 2% Ophthalmic Suspension in Subjects With Dry Eye - Effects on Central Cornea (NCT01057147) | Kubota Vision Inc. | 2010-02-01 |
| Study of DE-089 Ophthalmic Solution in Patients With Dry Eye (NCT01101984) | Santen Pharmaceutical Co., Ltd. | 2010-02-01 |
| Evaluation of an Investigational Lubricant Eye Drop on Lipid Layer Thickness (NCT01066988) | Alcon Research | 2010-01-01 |
| Acute Comfort and Blur Profile of a Lubricant Eye Drop Versus a Marketed Eye Ointment (NCT01076998) | Alcon Research | 2010-01-01 |
| A Clinical Evaluation Pilot Study of the Efficacy of Blink® Tears Lubricant Eye Drops for the Relief of Dry Eye Symptoms Following Implantation of Tecnis® Multifocal Introcular Lens (NCT01061268) | Innovative Medical | 2010-01-01 |
| Acute Comfort and Blur Profile of a Lubricant Eye Drop Versus a Marketed Lubricant Eye Gel (NCT01077011) | Alcon Research | 2010-01-01 |
| An Evaluation of the Safety and Efficacy of FID 114657 (NCT01030237) | Alcon Research | 2009-11-01 |
| Tear Film Thickness Measured Using a Novel Technique (NCT01014780) | Southern California College of Optometry at Marshall B. Ketchum University | 2009-11-01 |
| Evaluation of the Repeated Usage of Systane Ultra Eyedrop (NCT01051804) | Alcon Research | 2009-11-01 |
| Tear Film Break-Up Time Evaluation of FID 114657 (NCT01023464) | Alcon Research | 2009-10-01 |
| Using Impression Cytology to Observe the Cytological Changes of Ocular Surface Cells in Various Ocular Surface Disorders (NCT01387971) | National Taiwan University Hospital | 2009-09-01 |
| A Study Evaluating the Efficacy of SAR 1118 (0.1%, 1.0%, 5.0%) Ophthalmic Solution in Subjects With Dry Eye Conducted in a Controlled Adverse Environment (CAE) (NCT00926185) | Shire | 2009-08-03 |
| Efficacy, Tolerability, and Comfort of 0.3% Hypromellose Eyedrops in Patients Undergoing LASIK Surgery (NCT00909324) | Novartis Pharmaceuticals | 2009-08-01 |
| Acute Comfort and Haze Profile of FID 114657 (NCT00983203) | Alcon Research | 2009-07-01 |
| Barrier Function Measurement in Dry Eye Patients After Using Systane Ultra for 30 Days (NCT00946777) | Alcon Research | 2009-07-01 |
| Prospective Health Assessment of Cataract Patients' Ocular Surface (NCT01016405) | Innovative Medical | 2009-06-01 |
| A Study of AL-38583 Ophthalmic Solution 0.05%, 0.010% Versus AL-38583 Vehicle for Dry Eye (NCT00893139) | Alcon Research | 2009-06-01 |
| A Dose-Ranging Clinical Study to Assess the Safety and Efficacy of Subconjunctival Injection of Sirolimus in Patients With Dry Eye in the Controlled Adverse Environmental (CAE) Model (NCT00814944) | Santen Inc. | 2009-04-01 |
| Efficacy Study of Ketorolac and HPMC to Treat Dry Eye (NCT03693183) | ORA, Inc. | 2009-03-01 |
| A Study of Hydroxypropyl Guar Galactomannan 0.25% (HPGG) Versus Vehicle in Dry Eye Patients (NCT00840268) | Alcon Research | 2009-02-01 |
| A Natural History Study of Patients With Dry Eye (NCT00833235) | Allergan | 2009-02-01 |
| Evaluation of FID 114657 on Tear Film Lipid Layer Thickness (NCT00848068) | Alcon Research | 2009-01-01 |
| Kynex Versus Refresh Plus Study in Subject With Dry Eye (NCT00809198) | Alcon Research | 2008-12-01 |
| Salivary Gland Transplantation in the Treatment of Dry Eye in Patients With Stevens-Johnson Syndrome. (NCT01178242) | Federal University of São Paulo | 2008-12-01 |
| Residence Time Evaluation of Marketed OTC Ophthalmic Products (NCT00804791) | Alcon Research | 2008-11-01 |
| A Prospective, Randomized, Double-Masked, Single Center, Clinical Comparison of the Use of Systane Ultra in the Management of Dry Eyes in Bilateral Eyes (NCT00781092) | Durrie Vision | 2008-10-01 |
| Autologous Serum Efficacy Study in Patients With Severe Dry Eye (NCT00779987) | University of Chile | 2008-10-01 |
| Punctal Plug Study to Determine the Safety and Retention Times of Various Lengths of Canalicular Stents in Volunteers (NCT00743249) | Alcon Research | 2008-10-01 |
| A 2-week Clinical Comparison of SYSTANE® Ultra to Sensitive Eyes Rewetting Drops in Contact Lens Wearing Patients. (NCT00769665) | Alcon Research | 2008-10-01 |
| Osmoprotective Containing Lubricants in Dysfunctional Tear Syndrome and Post Refractive Surgery Patients (NCT01741987) | Federal University of São Paulo | 2008-10-01 |
| Acute Comfort and Blurring Profile Evaluation of Marketed Lubricant Eye Drops (NCT00756093) | Alcon Research | 2008-09-01 |