| Phase 2, Multi-center, Randomized, Double- Masked and Placebo-Controlled Study of YP-P10 Ophthalmic Solution Compared to Placebo in Subjects With Dry Eye (ICECAP 1) (NCT05467293) | Yuyu Pharma, Inc. | 2022-06-27 |
| PMCF Study to Evaluate Performance and Safety of "Hyaluronic Acid (HA)-Based Eyedrops" Used to Relieve Dry Eye Symptoms (NCT05807360) | C.O.C. Farmaceutici S.r.l. | 2022-06-24 |
| PMCF Study to Evaluate Performance and Safety of "CLHA-based Eyedrops" Used to Improve Lacrimal Abnormalities (NCT05823961) | C.O.C. Farmaceutici S.r.l. | 2022-06-10 |
| PMCF Study to Evaluate Performance and Safety of "Optrex Double Action Soothing and Lubricating Drops" (NCT05824000) | C.O.C. Farmaceutici S.r.l. | 2022-06-07 |
| AST Combined With 0.05% Cyclosporin Eye Drop Improve Corneal Nerve Density in Patients With SS Dry Eye (NCT06013436) | Chengdu University of Traditional Chinese Medicine | 2022-06-01 |
| Dailies Total 1 Sphere Contact Lenses (NCT05239494) | University of Alabama at Birmingham | 2022-05-23 |
| Ocular Effects of Scleral Lens Wear on Dry Eye Patients (NCT05079321) | University of Waterloo | 2022-04-14 |
| Herbal Medication to Treat Dry Eye in Peri/ Post-menopausal Women (NCT05319041) | Singapore National Eye Centre | 2022-04-11 |
| Efficacy of Low-Level Light Therapy in Reducing Dry Eye in Patients Undergoing Cataract Surgery (NCT05754437) | Azienda Ospedaliera Universitaria Mater Domini, Catanzaro | 2022-03-30 |
| Tear Lipid Layer Thickness Assessments With Perfluorohexyloctane Eye Drops (NCT05288582) | Ohio State University | 2022-03-27 |
| PMCF Study to Evaluate Performance and Safety of "Ocular Drops Based Upon Carmellose" Used to Relieve Dry Eye Symptoms (NCT05825352) | C.O.C. Farmaceutici S.r.l. | 2022-03-24 |
| Usability, Immediate, and 30 Day Effect of External Neuromodulation With iTEAR100 Generation 2 in Dry Eye Patients (NCT05304637) | Olympic Ophthalmics, Inc. | 2022-03-01 |
| Evaluating Impact of Systane iLux on Dryness Symptoms and Wearing Time in Contact Lens Users (NCT05306561) | Periman Eye Institute | 2022-01-26 |
| Safety and Efficacy Study on Cenegermin (Oxervate®) vs Vehicle in Severe Sjogren's Dry Eye Disease (PROTEGO-1 Study) (NCT05133180) | Dompé Farmaceutici S.p.A | 2022-01-19 |
| Dry Eye Response to Interval Exercise and Mediterranean Diet (NCT05248698) | Cairo University | 2022-01-05 |
| Phase II Clinical Study to Evaluate the Efficacy of Multidose Lagricel® Ofteno Ophthalmic Solution as Treatment for Dry Eye Disease. (NCT04704531) | Laboratorios Sophia S.A de C.V. | 2022-01-03 |
| Total30 Sphere Contact Lenses (NCT05183022) | University of Alabama at Birmingham | 2022-01-03 |
| Evaluation of Neovis® Total Multi Versus Systane® Balance on Ocular Dryness Associated With Meibomian Gland Dysfunction (NCT05191771) | Horus Pharma | 2022-01-01 |
| The Effect of Rinsing on Ocular Inflammation and Symptoms in Patients With Dry Eye Disease (NCT07618364) | Rinsada | 2022-01-01 |
| A Phase 3, Multi-Center Study Evaluating PL9643 in Patients with Dry Eye (NCT05201170) | Palatin Technologies, Inc | 2021-12-30 |
| Study to Compare the Efficacy of the Ophthalmic Solution Humylub Ofteno® PF With Hyabak® and Lagricel Ofteno® PF as Treatment for Dry Eye. (NCT04702776) | Laboratorios Sophia S.A de C.V. | 2021-12-09 |
| OC-01 (Varenicline) Nasal Spray and Dry Eye Signs and Symptoms in Daily Disposable Contact Lens Wearers (NCT05161208) | Center for Ophthalmic and Vision Research, LLC | 2021-12-03 |
| The Effect of 0.05% CsA Eye Drops on Diabetic Patients with Dry Eye Disease (NCT06824844) | Peking University Third Hospital | 2021-12-02 |
| Single Center, Prospective, Randomized, Controlled, Non-significant Risk (NCT03286166) | Toyos Clinic | 2021-12-01 |
| Meibomian Gland Probing in the Sub-Acute Phase of Patients With Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (NCT05145959) | Massachusetts Eye and Ear Infirmary | 2021-12-01 |
| A Study to Assess the Efficacy and Safety of Tanfanercept (HL036) Ophthalmic Solution in Participants With Dry Eye (NCT05109702) | HanAll BioPharma Co., Ltd. | 2021-11-18 |
| Effect of Povidone-iodine 5% Vs 1% on the Ocular Surface in Intravitreal Injections of Anti-VEGF (NCT06710951) | José Gerardo García Aguirre | 2021-11-15 |
| Efficacy and Safety of Topical Hydrocortisone on Signs and Symptoms of Dry Eye Associated to Meibomian Gland Dysfunction (NCT05159284) | Laboratorios Thea, Spain | 2021-11-09 |
| Causal Relationship Between Dry Eye and Accommodative Spasm (NCT05120401) | Far Eastern Memorial Hospital | 2021-11-05 |
| Strip Meniscometry in Dry Eye Evaluation (NCT06120894) | University Hospital Olomouc | 2021-11-01 |
| Evaluate the Safety and Effectiveness of The Tixel Fractional System in the Treatment of Meibomian Gland Disfunction (NCT04889950) | Novoxel Ltd. | 2021-10-26 |
| Performance and Tolerability of the Medical Device LACRIACT (NCT06159569) | Laboratórios Baldacci S.A | 2021-09-09 |
| The Effect of a Novel Blueberry Supplement on Dry Eye Disease (NCT05027087) | SightSage Foods and Nutrition Inc. | 2021-09-09 |
| An Exploratory Crossover Clinical Trial to Compare the Activity of Reproxalap and Lifitegrast in a Dry Eye Disease Chamber (NCT05102409) | Aldeyra Therapeutics, Inc. | 2021-09-09 |
| Efficacy of LipiFlow in Patients Affected by Meibomian Gland Dysfunction in Reducing Post-cataract Surgery Dry Eye (NCT05062564) | Azienda Ospedaliero-Universitaria Careggi | 2021-09-07 |
| Investigator Initiated Study to Assess the Efficacy of OC-01 (Varenicline) Nasal Spray on Signs and Symptoms of Dry Eye Disease Following Photorefractive Keratectomy (PRK) (NCT05045508) | Brandon Baartman | 2021-08-30 |
| The TRANQUILITY 2 Trial: A Phase 3 Clinical Trial to Assess the Efficacy and Safety in Subjects With Dry Eye Disease (NCT05062330) | Aldeyra Therapeutics, Inc. | 2021-08-28 |
| I-DROP MGD Symptomatic Relief and Tear Film Stability (NCT05011708) | I-MED Pharma | 2021-08-23 |
| Digital Device Users Who Are Treated With Systane Hydration PF (NCT04837807) | University of Alabama at Birmingham | 2021-08-18 |
| The DEPOT Study (Dry Eye Prescription Options for Therapy) (NCT04911361) | Research Insight LLC | 2021-08-10 |
| The Effect of Xiidra on Comfort and Dryness in Symptomatic Contact Lens Wearers (NCT04297618) | University of Waterloo | 2021-07-07 |
| Neurosensory Abnormalities in SymptomAtic Ocular Surface Patients (NASA) (NCT04838223) | Tufts Medical Center | 2021-07-02 |
| Evaluation of Comfort in Subjects With Moderate Dry Eye Disease (NCT04830956) | Alcon Research | 2021-06-30 |
| Role of Postoperative Lubrication in Cataract Surgery (NCT06555224) | Vienna Institute for Research in Ocular Surgery | 2021-06-22 |
| CEQUA for Sjogren's Syndrome Dry Eye (NCT04835623) | Center for Ophthalmic and Vision Research, LLC | 2021-06-21 |
| A Clinical Trial to Assess Subjects With Dry Eye Disease. (NCT04971031) | Aldeyra Therapeutics, Inc. | 2021-06-15 |
| Transcutaneous Auricular Vagus Nerve Stimulation in Dry Eye Disease With Meibomian Gland Dysfunction (NCT06544447) | Beijing Tongren Hospital | 2021-06-01 |
| Ocular Inflammation in Cataract Patients and Response to Treatment With Xiidra (NCT04120987) | Bucci Laser Vision Institute | 2021-05-31 |
| ALY688 Ophthalmic Solution in Subjects With Dry Eye Disease (NCT04899518) | Allysta Pharmaceutical | 2021-05-19 |
| Short and Long-term Results of Skin Versus Skin Plus Orbicularis Resection Blepharoplasty (NCT05528016) | Marmara University | 2021-05-01 |
| Safety And Effectiveness Of The TearCare® System In The Treatment Of The Signs And Symptoms Of Dry Eye Disease (SAHARA) (NCT04795752) | Sight Sciences, Inc. | 2021-04-28 |
| Effect on Ocular Surface Symptoms of Online Education (NCT04960696) | Kahramanmaras Sutcu Imam University | 2021-04-14 |
| The Chronology of Lifitegrast Effect on Anterior Surface Rehabilitation (CLEAR) Study (NCT04669561) | Research Insight LLC | 2021-03-17 |
| Effect of Traditional Chinese Medicine on Basic Tear Secretion and Tear Cytokines in Patients With Dry Eye Disease (NCT04785261) | China Medical University Hospital | 2021-03-16 |
| Safety and Efficacy of Dexamethasone Ophthalmic Insert (Dextenza®) in the Management of Clinically Significant Dry Eye (NCT04498468) | Johns Hopkins University | 2021-03-16 |
| A Study Evaluating HBM9036 Efficacy and Safety on Moderate to Severe Dry Eye (NCT04633213) | Harbour BioMed (Guangzhou) Co. Ltd. | 2021-02-25 |
| Post-marketing Study Focused on Evaluating I+Med's DayDrop for Improving Signs and Symptoms of Mild/Moderate Dry Eye (NCT06731725) | i+Med S.Coop. | 2021-02-17 |
| To Assess the Efficacy and Safety of OTX-DED for the Short-term Treatment of Signs and Symptoms of Dry Eye Disease (NCT04747977) | Ocular Therapeutix, Inc. | 2021-02-12 |
| Effect of Trigeminal Nerve Stimulation on Corneal Nerves and Chronic Ocular Pain (NCT04648085) | Instituto de Oftalmología Fundación Conde de Valenciana | 2021-02-03 |
| Detection of Acetylsalicylic Acid and Omega-3 Fatty Acids in Schirmers' Test Strips Using Mass Spectrometry (NCT05775536) | Medical University of Vienna | 2021-01-21 |
| Dry Eye Management With 3% Diquafosol Before and After Cataract Surgery (NCT04952987) | Mun Wai Lee | 2021-01-01 |
| Acupoint Therapy Device for Dry Eye (NCT06720428) | Shanghai 10th People's Hospital | 2021-01-01 |
| Evaluation of Ocular Surface in Hemodialysis Patients by Ocular Surface Analyzer (NCT04949295) | XiaoYong Liu | 2021-01-01 |
| Proteomics Analysis of Human Tears in the Diagnosis and Management of Dry Eye Disease (NCT07175909) | The Hong Kong Polytechnic University | 2021-01-01 |
| Clinical Cohort Study in Patients With Different Subtypes of Primary Sjogren Syndrome Related Dry Eye (NCT05605314) | Peking University Third Hospital | 2021-01-01 |
| Study of VVN001 Ophthalmic Solution in Dry Eye Disease (NCT04556838) | VivaVision Biotech, Inc | 2020-12-03 |
| Effect of Artificial Tears on the Parameters of the Eye and Its Impact on IOL Power Calculation for Cataract Surgery (NCT04706455) | Second Affiliated Hospital of Xi'an Jiaotong University | 2020-12-01 |
| Clinical Trial to Compare the Safety and Efficacy of Nanodrop® (NCT04111965) | Laboratorios Sophia S.A de C.V. | 2020-12-01 |
| Wireless Micropump in Dry Eye Patients (NCT04667819) | Tianjin Eye Hospital | 2020-12-01 |
| The TRANQUILITY Trial: Clinical Trial to Assess the Efficacy and Safety in Subjects With Dry Eye Disease (NCT04674358) | Aldeyra Therapeutics, Inc. | 2020-11-21 |
| Assess the Safety and Efficacy of CsA Ophthalmic Gel in Subjects With Moderate to Severe Dry Eye Disease (NCT04541888) | Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. | 2020-11-05 |
| Effects of Topical Insulin on Levels of Tear Inflammatory Mediators (NCT04877210) | Universiti Kebangsaan Malaysia Medical Centre | 2020-10-22 |
| A Study to Assess the Safety and Efficacy of ECF843 vs Vehicle in Subjects With Dry Eye Disease (NCT04391894) | Novartis Pharmaceuticals | 2020-10-06 |
| An Evaluation of the Clinical Utility and Safety of the Visant Medical Canalicular Plug (NCT04817085) | Visant Medical, Inc. | 2020-10-06 |
| Implementation of a Minor Ailment Service in Community Pharmacy Practice (NCT05247333) | Universidad de Granada | 2020-10-01 |
| Comparing Treatment of Dry Eye With Intracanalicular Dexamethasone, Restasis, and/or Lotemax (NCT04555694) | Thomas Chester, OD | 2020-10-01 |
| Study on Curative Effect and Mechanism of Acupuncture on Neuropathic Pain in Dry Eye Disease (NCT04668131) | Peking University Third Hospital | 2020-09-22 |
| Intracanalicular Dexamethasone Insert for the Treatment of Inflammation and Discomfort in Dry Eye Disease (DEcIDED) (NCT04527887) | Tufts Medical Center | 2020-09-04 |
| Safety and Efficacy of Intracanalicular Dexamethasone Compared to Loteprednol Etabonate in Patients With Keratoconus (NCT04418999) | Illinois College of Optometry | 2020-09-01 |
| Study to Evaluate the Efficacy of SDP-4 in Subjects With Dry Eye Disease (DED) (SDP-4-CS202) (NCT04535947) | Silk Technologies, Ltd. | 2020-08-14 |
| A Randomized Study of Smile Exercise for Dry Eye (NCT04421300) | Zhongshan Ophthalmic Center, Sun Yat-sen University | 2020-07-02 |
| Effect of Re-esterified Triglyceride (rTG) Form Omega-3 Supplements on Dry Eye Following Cataract Surgery (NCT04411615) | Samsung Medical Center | 2020-07-01 |
| Epidemiological Study of Dry Eye Disease in Stavanger: Dry Eye Disease in Patients Treated With Intravitreal Injections (NCT04458012) | Helse Stavanger HF | 2020-06-25 |
| Clinical Outcome of Lipiflow Treatment Prior to Cataract Surgery in Dry Eye Patients (NCT04457999) | Samsung Medical Center | 2020-03-20 |
| Meibomian Gland Dysfunction Treatment (NCT04229888) | Indiana University | 2020-02-26 |
| Evaluation of Tangible Boost for Patients With Stevens Johnson Syndrome, Sjogren's Syndrome, and Graft Vs Host Disease (NCT04313725) | Tangible Science | 2020-02-24 |
| Effect of UMSCs Derived Exosomes on Dry Eye in Patients With cGVHD (NCT04213248) | Zhongshan Ophthalmic Center, Sun Yat-sen University | 2020-02-21 |
| Efficacy and Safety of Ikervis Under Controlled Environmental Conditions Environment (NCT04492878) | Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA | 2020-02-04 |
| Clinical Efficacy of Two Topical Dry Eye Drops for Central Corneal Stain Clearing Over 90 Days (NCT04172961) | Toyos Clinic | 2020-02-01 |
| Lipiflow vs iLux Patient Acceptance and Comfort Study (NCT04454983) | Epstein, Arthur B., OD, FAAO | 2020-01-11 |
| Dry Eye Screening and Referral System (NCT04413370) | Sun Yat-sen University | 2020-01-06 |
| Phase 3 Study of the Safety and Efficacy of OmegaD Softgels in the Treatment of Dry Eye Disease (NCT04181593) | OmegaD LLC | 2019-11-18 |
| Investigating iLux Efficacy in Contact Lens Wearers With Evaporative Dry Eye Disease (NCT04159935) | University of Waterloo | 2019-11-15 |
| Analysis of the Diagnostic Performance of LacryDiag, a New Analyzer of the Ocular Surface in the Dry Eye (NCT04093037) | Centre Hospitalier Universitaire de Saint Etienne | 2019-11-14 |
| Evaluating HA 0.15% Compared With Cyclosporine 0.05%, and Efficacy of Combination Therapy in Dry Eye Disease Patients (NCT04127851) | Taejoon Pharmaceutical Co., Ltd. | 2019-11-12 |
| Treatment With Allogeneic Adipose-derived Mesenchymal Stem Cells in Patients With Aqueous Deficient Dry Eye Disease (NCT03878628) | Rigshospitalet, Denmark | 2019-10-16 |
| Use of Prophylactic Lubricating Drops After Cataract Surgery (NCT04131335) | Guy's and St Thomas' NHS Foundation Trust | 2019-10-14 |
| Predicting the Success of Dry Eye Disease Interventions Using Clinical Tests (NCT04125134) | Tufts Medical Center | 2019-10-03 |
| Liposomal Sirolimus in Dry Eye Disease (NCT04115800) | Instituto de Oftalmología Fundación Conde de Valenciana | 2019-10-02 |
| Refitting Daily Disposable Contact Lens Wearers With Dry Eye Disease With A Different Daily Disposable Lens Type (NCT04105842) | University of Waterloo | 2019-09-23 |