| Probiotic in Dry Eye Syndromes (NCT04938908) | Shiraz University of Medical Sciences | 2021-07-01 |
| Treatment of Dry Eye Disease Using Pro-ocular™ - A Proof of Concept, Safety, and Efficacy Study (NCT04884217) | PharmaDax Inc. | 2021-05-20 |
| Objective Measurement With TCM Pattern for AIDDES (NCT04747288) | Taipei Veterans General Hospital, Taiwan | 2021-02-01 |
| Comprehensive Study on Dry Eye and Ocular Surface Disease Prior and After Cataract Surgery (NCT04711642) | Fundación Oftalmológica Los Andes | 2021-01-15 |
| Evaluating the Efficacy and Safety of TJO-087 in Moderate to Severe Dry Eye Disease Patients (NCT05245604) | Taejoon Pharmaceutical Co., Ltd. | 2020-06-19 |
| A Study of the Drugs AGN-242428 and AGN-231868 in Participants With Dry Eye Disease (NCT04030962) | AbbVie | 2020-03-04 |
| Proteomic and Metabolomic Lacrimal Fingerprint in Diverse Pathologies of the Ocular Surface (NCT04198740) | Centre hospitalier de l'Université de Montréal (CHUM) | 2020-02-01 |
| Safety and Efficacy of BRM421 for Dry Eye Syndrome Treatment (NCT04343287) | BRIM Biotechnology Inc. | 2020-01-15 |
| Vehicle-Controlled Study of SkQ1 as Treatment for Dry-eye Syndrome (NCT04206020) | Mitotech, SA | 2019-12-20 |
| Dose Ranging Study to Assess the Efficacy and Safety of Voclosporin Ophthalmic Solution in Subjects With Dry Eye Syndrome (NCT04147650) | Aurinia Pharmaceuticals Inc. | 2019-10-14 |
| Safety, PK and Efficacy Study of SJP-0132 in Subjects With Dry Eye Disease (NCT04139122) | Senju Pharmaceutical Co., Ltd. | 2019-10-05 |
| Heidelberg In Vivo Confocal Microscopy to Evaluate the Ocular Surface Disorders of Healthy and Diseased Individuals (NCT04025801) | National Taiwan University Hospital | 2019-07-31 |
| To Demonstrate the Non-inferiority of Eyestil Protection® Compared to Vismed® in Terms of Clinical Performance (NCT03803722) | SIFI SpA | 2019-07-08 |
| A Study to Evaluate Safety and Efficacy of rhNGF Eye Solution vs Vehicle in Patients With Moderate to Severe Dry Eye (NCT03982368) | Dompé Farmaceutici S.p.A | 2019-06-10 |
| Objective Measurement Methods for Autoimmune Disease and Dry Eye Syndrome (NCT03937271) | Taipei Veterans General Hospital, Taiwan | 2019-04-01 |
| Dry Eye Syndrome Description During Cataract Surgery, With Multimodal Analysis of the Ocular Surface (NCT03923244) | University Hospital, Clermont-Ferrand | 2019-04-01 |
| Study of TOP1630 for Dry Eye Syndrome (NCT03833388) | Topivert Pharma Ltd | 2019-02-13 |
| Study of SkQ1 as Treatment for Dry-eye Syndrome (NCT03764735) | Mitotech, SA | 2018-12-06 |
| Assessment of the Mu-Drop System for Serum Eye Drops (NCT03539159) | Sanquin Research & Blood Bank Divisions | 2018-12-06 |
| Efficacy, Safety of T2769 in Dry Eye Disease (NCT03830359) | Laboratoires Thea | 2018-09-01 |
| DRy Eye Outcome and Prescription Study (NCT03652415) | Guy's and St Thomas' NHS Foundation Trust | 2018-08-23 |
| The Effect of Manuka Eye Drops on Tear Film Properties (NCT03622619) | The University of New South Wales | 2018-08-13 |
| Piiloset Trehalose Emulsion Eye Drop Study in Moderate or Severe Dry Eye (NCT03569202) | Kuopio University Hospital | 2018-05-21 |
| Functional MRI Study of Cortical Modifications to Light Stimulation in Patients With Photophobia (NCT03464357) | University Hospital, Toulouse | 2018-03-13 |
| Comparison of Ocular Surface Features in Patients With Diabetes and Dry Eye Syndrome (NCT03576300) | Peking University Third Hospital | 2018-02-01 |
| Corneal Tear Film Imaging of the Cornea Before and After Restasis Therapy (NCT03403023) | Meir Medical Center | 2018-01-30 |
| Efficacy and Safety of HU007 Eye Drops in Patients With Dry Eye Syndrome (NCT03461575) | Huons Co., Ltd. | 2018-01-22 |
| Effectiveness of Intense Pulsed Light for Improving Dry Eye Syndrome (NCT03396913) | Lumenis Be Ltd. | 2018-01-10 |
| A Multi-Center, Randomized, Double Masked, Parallel-Group, Vehicle-Controlled, Clinical Study to Assess the Safety and Efficacy of Reproxalap Ophthalmic Solution in Subjects With Dry Eye Disease (NCT03404115) | Aldeyra Therapeutics, Inc. | 2018-01-02 |
| Clinical Study to Investigate the Efficacy and Safety of Orally Administered SA001 in Patients With Dry Eye Syndrome. (NCT03723798) | Samjin Pharmaceutical Co., Ltd. | 2017-11-08 |
| Allogeneic Versus Autologous Serum Eye Drops (NCT03085290) | Sanquin Research & Blood Bank Divisions | 2017-06-26 |
| Safety and Efficacy of BRM421 for Dry Eye Syndrome (NCT03066219) | BRIM Biotechnology Inc. | 2017-02-07 |
| Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome : ARISE-2 (NCT02974907) | ReGenTree, LLC | 2016-11-01 |
| Efficacy Comparison of Two Kinds of Treatment in Treating Dry Eye Caused by Meibomian Gland Dysfunction (NCT02958514) | Peking University Third Hospital | 2016-11-01 |
| Acute Tear Production Following Single Use of the Oculeve Intranasal Neurostimulator (NCT02798289) | Oculeve, Inc. | 2016-06-01 |
| Optical Coherence Tomography of Ocular Structures in Epiphora and Dry Eye Syndrome. (NCT02849093) | Bedford Hospital NHS Trust | 2016-06-01 |
| Influencing Factors on Dry Eye Syndrome and Ocular Surface Disease (NCT03364322) | Hallym University Kangnam Sacred Heart Hospital | 2016-06-01 |
| Exploring Immune Cell Signatures in Autoimmunity and Dry Eye Syndrome (NCT02715323) | Singapore National Eye Centre | 2016-05-01 |
| Cross-linked Hyaluronic Acid and Coenzyme Q10 in the Treatment of Dry Eye (NCT03074344) | Azienda Ospedaliera Universitaria Policlinico "G. Martino" | 2016-05-01 |
| Study to Evaluate the Efficacy and Safety of CKD-350 (NCT02777723) | Chong Kun Dang Pharmaceutical | 2016-05-01 |
| Efficacy and Safety Study of HU00701/HU007 Eye Drops in Patients With Dry Eye Syndrome (NCT02917512) | Huons Co., Ltd. | 2016-03-01 |
| A Study to Evaluate the Safety and Effectiveness of Oculeve Intranasal Lacrimal Neurostimulator in Participants With Dry Eye Syndrome (NCT02680158) | Oculeve, Inc. | 2016-01-31 |
| Comparing the Quality of Topical Autologous Serum in Different Etiologies of Dry Eye Syndrome (NCT02774707) | National Taiwan University Hospital | 2016-01-01 |
| Evaluation of Factors Affecting the Tear-film Lipid Layer Thickness (NCT02645045) | Yonsei University | 2015-12-11 |
| The Comparison of 50% AS Versus PFAT+ 0.05 % COE in Severe Dry Eye Syndrome (NCT03666884) | Seref istek | 2015-10-10 |
| Evaluation of Tear Osmolarity Over Time With Sustained Use of Thera Tears Lubricating Drops (NCT02758327) | Koffler Vision Group | 2015-10-01 |
| Assessment of the Safety and Efficacy of RGN-259 Ophthalmic Solutions for Dry Eye Syndrome: ARISE-1 (NCT02597803) | ReGenTree, LLC | 2015-09-01 |
| A Retrospective Analysis of Restasis® Benefits in Dry Eye Contact Lens Patients (NCT02522312) | Hazleton Eye Specialists | 2015-09-01 |
| Tolerability, Safety and Efficacy of Lubricin Versus Sodium Hyaluronate Eye Drops in Patients With Moderate Dry Eye (NCT02507934) | Dompé Farmaceutici S.p.A | 2015-06-26 |
| Clinical Evaluation Following Use of SYSTANE® ULTRA in the Management of Dry Eye (NCT02446015) | Alcon Research | 2015-06-19 |
| Dose-finding Study to Assess the Safety and Effect of SYL1001 in Patients With Ocular Pain (NCT02455999) | Sylentis, S.A. | 2015-06-01 |
| Tolerability, Safety and Efficacy of Lubricin vs Sodium Hyaluronate Eye Drops in Subjects With Moderate Dry Eye (NCT02510235) | Dompé Farmaceutici S.p.A | 2015-03-09 |
| Study of ST266 Eye Drops in Treating Dry Eye (NCT02369861) | Noveome Biotherapeutics, formerly Stemnion | 2015-03-01 |
| The Effect of Eyelid Surgery on Dry Eye - a Prospective Study (NCT02376556) | Sheba Medical Center | 2015-03-01 |
| Point of Care Testing of Inflammatory Markers in Tears (NCT02315079) | University of Florida | 2015-01-01 |
| Assessment of Tear Film Thickness by Optical Coherence Tomography in Healthy Subjects and Subjects With Dry Eye Disease (NCT01753596) | Medical University of Vienna | 2014-12-01 |
| Phase 2 Study With Cis-UCA Ophthalmic Solutions in Subjects With Dry Eye (NCT02326090) | Herantis Pharma Plc. | 2014-12-01 |
| Changes in Tear Osmolarity Over Time With Sustained Use of TheraTears (NCT02100787) | Jenkins Eye Care | 2014-04-10 |
| Pilot Study to Clinical Evaluate Device Prototypes in Dry Eye Patients (NCT01957670) | Lacrima Medical LTD | 2014-02-01 |
| Safety and Efficacy of rhNGF Eye Drops at Different Doses in Patients With Dry Eye (NCT02101281) | Dompé Farmaceutici S.p.A | 2014-01-20 |
| Efficacy and Safety of T2762 and Vismed® in Dry Eye Syndrome (NCT02023268) | Laboratoires Thea | 2013-12-01 |
| Safety and Efficacy of PG101 for Dry Eye Syndrome (NCT02078661) | Rhodes Pharmaceuticals, L.P. | 2013-12-01 |
| Effect of Olixia Pure® Eye Drops on Tear Film Thickness in Healthy Subjects (NCT01970917) | Medical University of Vienna | 2013-10-01 |
| IPL and Meibomian Gland Expression to Treat Ocular Rosacea Ocular GVHD (NCT02066051) | Mayo Clinic | 2013-10-01 |
| Clinical Evaluation of Systane® ULTRA Compared to OPTIVE® in Ocular Surface Staining (NCT01863368) | Alcon Research | 2013-09-01 |
| Investigation on Medical Management of Dry Eye Patients (NCT01942226) | National Cheng Kung University | 2013-08-01 |
| The Effect of Intravenous Glucocorticoids on the Tearfilm in Eyes With Thyroid-associated Ophthalmopathy (NCT01579539) | Medical University of Vienna | 2013-06-27 |
| Efficacy of Pulsed Light Therapy for Meibomian Gland Dysfunction and Dry Eye Syndrome (NCT01917539) | University of Miami | 2013-06-01 |
| Efficacy and Safety of HE10 for Dry Eye Syndrome (NCT02492412) | Huons Co., Ltd. | 2013-05-01 |
| Influence of Lachrymal Substitutes on Tear Film Thickness in Patients With Moderate Dry Eye Syndrome (NCT01864330) | Medical University of Vienna | 2013-05-01 |
| Treatment of Meibomian Gland Dysfunction Prior to Cataract Surgery (NCT01808560) | TearScience, Inc. | 2013-03-01 |
| Effects of Dry Eye Treatments on the Ocular Surface (NCT01797822) | Baylor College of Medicine | 2013-02-01 |
| SYSTANE® Family - Meibomian Deficiency (NCT01733745) | Alcon Research | 2013-02-01 |
| Evaluation of SYSTANE® BALANCE in Dry Eye Subjects With Lipid Deficiency (NCT01688726) | Alcon Research | 2012-12-01 |
| Pilot Study to Evaluate SYL1001 Safety and Effect in Patients With Ocular Pain (NCT01776658) | Sylentis, S.A. | 2012-11-01 |
| A Multi-Center Study Subjects With Dry Eye Syndrome (NCT01745887) | Eleven Biotherapeutics | 2012-11-01 |
| Phase 2 Study to Evaluation the Safety and Efficacy of Orally Administered KL7016 in Patients With Dry Eye Syndrome (NCT02092207) | Yungjin Pharm. Co., Ltd. | 2012-10-01 |
| Evaluation of the Corneal Residence Time of Chitosan-N-acetylcysteine Eye Drops in Patients With Dry Eye Syndrome After Single and Multiple Instillation (NCT01753752) | Gerhard Garhofer | 2012-09-01 |
| Clinical Evaluation of a Daily Disposable Contact Lens in Symptomatic Weekly/Monthly Lens Wearers (NCT01614600) | Alcon Research | 2012-06-01 |
| Efficacy and Safety of Rebamipide in Subjects With Dry Eye Syndrome (NCT01632137) | Kubota Vision Inc. | 2012-06-01 |
| Phase II Study of DA-6034 Eye Drops in Dry Eye Syndrome (NCT01670357) | Dong-A ST Co., Ltd. | 2012-04-01 |
| Oral Nutrition Impact on Tear Film (NCT01561040) | Eye and Vision Technologies and Research Institute | 2012-03-01 |
| Efficacy and Safety of PRO-148 Ophthalmic Solution Versus SYSTANE® in the Treatment of Patients With Dry Eye Syndrome (NCT01541891) | Laboratorios Sophia S.A de C.V. | 2011-10-01 |
| Correlation of Different Signs for Assessment of Dry Eye Syndrome (NCT01753687) | Medical University of Vienna | 2011-09-01 |
| Safety and Efficacy of Thymosin Beta 4 Ophthalmic Solution in Patients With Dry Eye (NCT01387347) | ReGenTree, LLC | 2011-08-01 |
| Sodium Hyaluronate Ophthalmic Solution, 0.18% for Treatment of Dry Eye Syndrome (NCT01382225) | Alcon Research | 2011-07-01 |
| Assessment of Safety and Tolerability of Chitosan-N-acetylcysteine Eye Drops in Subjects While Wearing Contact Lenses and Before Insertion of Contact Lenses (NCT01747616) | Medical University of Vienna | 2011-07-01 |
| Evaluation of the Effect of Repeated Usage on the Tear Film Characteristics of an Investigational Eye Drop in Dry Eye Sufferers (NCT01339936) | Optometric Technology Group Ltd | 2011-03-01 |
| Reproducibility of Tearfilm Osmolarity Measurements Using TearLab® in Patients With Dry Eye Syndrome and Healthy Subjects (NCT01744457) | Medical University of Vienna | 2011-02-01 |
| In Vivo Measurement of Corneal Epithelial Changes in Dry Eye Patients (NCT01483989) | Alcon Research | 2011-02-01 |
| Evaluating Safety and Efficacy of FID 112903 Post Discontinuation of Long-term Use of RESTASIS® (Cyclosporine Ophthalmic Emulsion) 0.05% (NCT01198782) | Alcon Research | 2010-09-01 |
| A Dose Ranging Study to Evaluate Safety and Efficacy of Bromfenac Ophthalmic Solution in Dry Eye Disease (NCT01212471) | Bausch & Lomb Incorporated | 2010-09-01 |
| An Open-Label, Single-Center Study Evaluating the Effect of Systane Balance on Video Ocular Protection Index (OPI) and Blink Patterns in Patients Diagnosed With Dry Eye (NCT01223040) | Alcon Research | 2010-08-01 |
| Non-invasive Ocular Surface Measurements Before and After Interventions (NCT01228929) | University of Rochester | 2010-07-01 |
| Study to Assess the Safety and Efficacy of BOL-303242-X Ophthalmic Suspension in Dry Eye Syndrome (NCT01163643) | Bausch & Lomb Incorporated | 2010-07-01 |
| Oral Omega-3 Fatty Acids in the Treatment of Dry Eye Syndrome (NCT01107964) | Milton S. Hershey Medical Center | 2010-07-01 |
| Treatment of Dry Eye Using 0.03% Tacrolimus Eye Drops (NCT01850979) | University of Sao Paulo General Hospital | 2010-02-01 |
| The Effect of a New Emulsion in Dry Eye Patients on Tear Layer Aberrometry, Contrast Sensitivity, and Reading Ability (NCT01013077) | Southern California College of Optometry at Marshall B. Ketchum University | 2009-11-01 |
| Safety and Efficacy of Two Artificial Tears in Dry Eye Subjects (NCT01010282) | Allergan | 2009-11-01 |
| Safety and Tolerability of Artificial Tears in Dry Eye Subjects (NCT00932477) | Allergan | 2009-08-01 |