| Custom Needle Preparation for Suprachoroidal Steroid Injection (One Year Results) (NCT05496530) | Benha University | 2022-07-10 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of RO7446603 Administered Alone or in Combination With Aflibercept or Faricimab in Participants With Diabetic Macular Edema (NCT06850922) | Genentech, Inc. | 2022-06-22 |
| Comparing Conventional Grid Laser Photocoagulation and Subthreshold Micropulse Laser in Diabetic Macular Edema Using OCT Angiography (NCT05416099) | Chinese University of Hong Kong | 2022-06-01 |
| A Single Ascending Dose Cohort Study of AG-73305 in DME Patients (NCT05301751) | Allgenesis Biotherapeutics Inc. | 2022-05-19 |
| Systemic and Local Inflammatory Biomarkers in the Treatment of Refractory Diabetic Macular Edema (NCT06179030) | Saglik Bilimleri Universitesi | 2022-05-01 |
| Bangladesh PRODUCTIVity in Eyecare Trial (NCT05182580) | Orbis | 2022-03-20 |
| A Study to Investigate Faricimab Treatment Response in Treatment-Naive, Underrepresented Patients With Diabetic Macular Edema (NCT05224102) | Genentech, Inc. | 2022-02-28 |
| Efficacy and Safety of 9MW0813 in Subjects With Diabetic Macular Edema (NCT05324774) | Mabwell (Shanghai) Bioscience Co., Ltd. | 2022-02-28 |
| Aqueous Biomarker Levels in Diabetic Retinopathy and Diabetic Macular Edema (NCT05333055) | Greater Houston Retina Research | 2022-02-10 |
| Detection and Classification of Diabetic Retinopathy From Posterior Pole Images With A Deep Learning Model (NCT04805541) | Ural Telekomunikasyon Sanayi Ticaret Anonim Sirketi | 2022-02-01 |
| A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of D-4517.2 After Subcutaneous Administration in Healthy Participants (NCT05105607) | Ashvattha Therapeutics, Inc. | 2022-01-11 |
| Anti-VEGF in Real-world (NCT05222633) | Wenbin Wei | 2022-01-01 |
| A Study to Investigate Vamikibart (RO7200220) in Diabetic Macular Edema (NCT05151731) | Hoffmann-La Roche | 2021-12-31 |
| A Study to Investigate Vamikibart (RO7200220) in Combination With Ranibizumab in Diabetic Macular Edema (NCT05151744) | Hoffmann-La Roche | 2021-12-17 |
| High Resolution Optical Coherence Tomography (NCT05130385) | Insel Gruppe AG, University Hospital Bern | 2021-11-30 |
| Effect of Ranibizumab Versus Bevacizumab on the Macular Perfusion in Diabetic Macular Edema (NCT04991350) | Cairo University | 2021-11-26 |
| Evaluation of IBI302 Injection in nAMD or DME (NCT05961007) | Innovent Biologics (Suzhou) Co. Ltd. | 2021-11-18 |
| EffiCacy, Safety and ToLErability of a Novel Ocular ANtiseptic for Ocular Use (CLEAN) (NCT05127525) | iRenix Medical, Inc. | 2021-11-15 |
| A 3-month Study to Compare the Safety of ONS-5010 in Vials Versus Pre-filled Syringe in Subjects With Visual Impairment Due to Retinal Disorders (NCT05112861) | Outlook Therapeutics, Inc. | 2021-11-15 |
| A Pivotal Safety and Efficacy Study of OCS-01 Eye Drops in Participants With Diabetic Macular Edema (DIAMOND 1) (NCT05066997) | Oculis | 2021-10-19 |
| Efficacy and Safety of Intravitreal Injection of Bevacizumab with and Without Oral Curcumin (NCT06595355) | Isfahan University of Medical Sciences | 2021-10-10 |
| Combined Intravitreal Bevacizumab With Topical Timolol-Dorzolamide Eye Drops in Diabetic Macular Edema (NCT05083689) | Shahid Beheshti University of Medical Sciences | 2021-10-06 |
| Observational Study of Vision Improvement in Patients With Retinal Disorders (NCT04693702) | Optimal Acuity Corporation | 2021-10-01 |
| A Study to Evaluate THR-687 Treatment for Diabetic Macular Oedema. (NCT05063734) | Oxurion | 2021-08-27 |
| First-In-Human Study of CU06-1004 Following Single and Multiple Ascending Doses in Healthy Volunteers (NCT04795037) | Curacle Co., Ltd. | 2021-07-15 |
| Epidemiologic Assessment of Diabetic Retinopathy in Egypt Using Ultrawide Field Fundus Photographs (NCT04935749) | Alexandria University | 2021-07-01 |
| Diabetic Macular Edema: Relevance of Staging Progression on Therapeutic Outcome (NCT05080803) | European School of Advanced Studies in Ophthalmology | 2021-06-01 |
| Ozurdex in Suboptimal Diabetic Macular Edema Patients (NCT04856397) | Uptown Eye Specialists | 2021-05-25 |
| Clinical Study to Evaluate PRO-169 for Diabetic Macular Edema (NCT05217680) | Laboratorios Sophia S.A de C.V. | 2021-05-24 |
| Study of the Safety and Efficacy of APX3330 in Diabetic Retinopathy (NCT04692688) | Ocuphire Pharma, Inc. | 2021-04-08 |
| Study Comparing Two Populations of Patients Treated With Anti VEGF for Diabetic Macular Edema, One Being Followed at the Hospital and the Other One Being Followed at Home Using a Software Allowing Self-assessment of Visual Acuity (NCT04776343) | Hospital St. Joseph, Marseille, France | 2021-04-01 |
| Validation Study of RETINA-AI Galaxy™, an Automated Diabetic Retinopathy Screening Device (NCT04774822) | RETINA-AI Health, Inc. | 2021-03-25 |
| Evaluation of RC28-E Injection in Diabetic Macular Edema (NCT04782115) | RemeGen Co., Ltd. | 2021-03-17 |
| The Effect of Ocular Rinse Volume on Surface Irritation After Intravitreal Injections (NCT05615805) | University of Oklahoma | 2021-03-01 |
| Safety and Efficacy of 9MW0813 in Subjects With Diabetic Macular Edema (NCT05324592) | Mabwell (Shanghai) Bioscience Co., Ltd. | 2021-02-26 |
| Laser vs Bevacizumab Injection Alone in Treatment of Diabetic Macular Edema (NCT02229175) | University of California, San Francisco | 2021-01-01 |
| Comparing the Compliance to Follow-up in Patients With Diabetic Macular Edema (NCT05019807) | Lions Club International Foundation | 2020-12-18 |
| A Study to Evaluate the Safety, Tolerability and Pharmacokinetics of IVT MHU650 in Macular Edema Patients (NCT04635800) | Novartis Pharmaceuticals | 2020-12-10 |
| Effect on Pain and Inflammation With DEXTENZA Treatment in Patients Undergoing Intravitreal Anti-VEGF Injections (NCT04563299) | Retina Vitreous Associates of Florida | 2020-12-09 |
| A Pharmacokinetic stuDy of intRavitreal Aflibercept Injection in Vitrectomized and Non-vitrectomized Eyes With Diabetic Macular Edema (NCT04588948) | Stanford University | 2020-12-01 |
| Pilot and Phase 2 Study of the Efficacy of a Treatment Protocol With Dexamethasone Implant Loading Dose in Patients With Diabetic Macular Edema (LOADEX) (NCT04116398) | Hospices Civils de Lyon | 2020-11-30 |
| A Study to Investigate Aqueous Humor and Multimodal Imaging Biomarkers in Treatment-Naïve Participants With Diabetic Macular Edema Treated With Faricimab (NCT04597918) | Hoffmann-La Roche | 2020-11-25 |
| Extension Study of MYL-1701P-3001 for Safety and Efficacy (NCT04674800) | Mylan Pharmaceuticals Inc | 2020-11-23 |
| Time Efficiency Comparison of Two IntraVitreal Injection Techniques (NCT04455399) | Peregrine Eye and Laser Institute | 2020-11-09 |
| Study of Two Multiple Intravitreal Doses of BAT5906 for Safety and Efficacy in Patients With Diabetic Macular Edema (NCT04772105) | Bio-Thera Solutions | 2020-10-16 |
| Safety and Tolerability Study of UBX1325 in Patients With Diabetic Macular Edema or Neovascular Age-Related Macular Degeneration (NCT04537884) | Unity Biotechnology, Inc. | 2020-10-08 |
| A 3-month Study to Assess the Safety of ONS-5010 in Subjects With Visual Impairment Due to Retinal Disorders (NCT04516278) | Outlook Therapeutics, Inc. | 2020-10-01 |
| A Trial to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Participants With Diabetic Macular Edema (DME) (NCT04611152) | Kodiak Sciences Inc | 2020-09-30 |
| A Study to Evaluate the Efficacy, Durability, and Safety of KSI-301 Compared to Aflibercept in Participants With Diabetic Macular Edema (DME) (NCT04603937) | Kodiak Sciences Inc | 2020-09-30 |
| Pre-vitrectomy Intravitreal Ranibizumab for Patients With Proliferative Diabetic Retinopathy Combined With Diabetic Macular Edema (NCT04464694) | Xinhua Hospital, Shanghai Jiao Tong University School of Medicine | 2020-09-01 |
| A Study of Intravitreal ILUVIEN® Implant as Baseline Therapy in Patients With Early Diabetic Macular Edema (DME) (NCT04469595) | Alimera Sciences | 2020-08-31 |
| A Study to Evaluate THR-149 Treatment for Diabetic Macular Oedema (NCT04527107) | Oxurion | 2020-07-31 |
| Intravitreal Ranibizumab Versus Its Combination With Dexamethasone in The Treatment of Diabetic Macular Edema (NCT05271539) | Cairo University | 2020-07-01 |
| Study of a High-Dose Aflibercept in Participants With Diabetic Eye Disease (NCT04429503) | Regeneron Pharmaceuticals | 2020-06-29 |
| MS-553 in Diabetic Retinopathy Patients With Central Involved Macular Edema (NCT04187443) | Shenzhen MingSight Relin Pharmaceuticals Co., Ltd. | 2020-06-02 |
| ADVM-022 Intravitreal Gene Therapy for DME (NCT04418427) | Adverum Biotechnologies, Inc. | 2020-05-28 |
| Collateral Damage From the COVID-19 Pandemic Observed in Patients Treated With Intravitreal Injections (IVT) of Anti-angiogenic Agents (NCT04395859) | Fondation Ophtalmologique Adolphe de Rothschild | 2020-05-27 |
| Cataract DME - Peri vs. Intraop (NCT03920878) | Emory University | 2020-05-01 |
| Comparative Study of Dexamethasone Implant to Intravitreal Aflibercept in Subjects With Diabetic Macular Edema (NCT04411693) | The Cleveland Clinic | 2020-04-10 |
| Changes in Optical Coherence Tomography Leakage Mapping in Diabetic Macular Edema After Conbercept Treatment (NCT04254536) | Renmin Hospital of Wuhan University | 2020-02-01 |
| Influence of Cataract Surgery on Early DME The DICAT-II Study (NCT04096131) | European School of Advanced Studies in Ophthalmology | 2020-01-28 |
| Intravitreal Dexamethasone Implant (Ozurdex) Versus Bevacizumab in Patients With Diabetic Macular Edema Undergoing Cataract Surgery (NCT04067856) | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | 2020-01-01 |
| Computer-based Tutorial and Automated Speech Recognition for Intravitreal Drug Injections (NCT04142164) | Prim. Prof. Dr. Oliver Findl, MBA | 2019-10-24 |
| A Study to Evaluate Efficacy, Safety & Pharmacokinetics of the Port Delivery System (PDS) With Ranibizumab in Participants With Diabetic Macular Edema (DME) Compared With Intravitreal Ranibizumab; A Substudy to Evaluate the Safety of Re-implanting the PDS With Ranibizumab in Participants With DME (NCT04108156) | Hoffmann-La Roche | 2019-09-30 |
| A Depot Formulation of Sunitinib Malate (GB-102) in Subjects With Diabetic Macular Edema and Retinal Vein Occlusion (NCT04085341) | Graybug Vision | 2019-09-11 |
| A Study to Evaluate the Effectiveness and Safety of OZURDEX® in Patients With Diabetic Macular Edema But Never Treated (NCT03953807) | Allergan | 2019-09-05 |
| Combination OZURDEX® & EyLea® vs. OZURDEX® Monotherapy in IncompLete-Responders wIth Diabetic Macular Edema (NCT03629210) | Pradeepa Yoganathan | 2019-09-01 |
| Aflibercept for Diabetic Macular Edema In Real-life Practice in GREece (NCT05683912) | University of Athens | 2019-09-01 |
| IVI Aflibercept Before and After Phaco in DME. (NCT05731089) | Al Hadi Hospital | 2019-09-01 |
| Combined Ranibizumab and Iluvien for Diabetic Macular Oedema (NCT03784443) | Imperial College London | 2019-09-01 |
| To Compare Brolucizumab to Aflibercept in Chinese Patients With Visual Impairment Due to Diabetic Macular Edema (NCT04058067) | Novartis Pharmaceuticals | 2019-08-23 |
| Anti-VEGF Intravitreous Injections for Diabetic Macular Edema in Patients Undergoing Cataract Surgery (NCT04063358) | Second Military Medical University | 2019-08-22 |
| Increase in Capillary Plexus Density Level Following the Use of Ozurdex for the Treatment of DME (NCT04038125) | Retina Macula Specialists of Miami, LLC | 2019-08-22 |
| A Study to Investigate RO7200220 as Monotherapy and in Combination With Ranibizumab in Participants With Diabetic and Uveitic Macular Edema (NCT06771271) | Hoffmann-La Roche | 2019-07-22 |
| Povidone Iodine vs AVEnova: A Pre-injection Disinfection Study (PAVE Study) (NCT04018482) | California Retina Consultants | 2019-07-16 |
| A Study Assessing AR-13503 Implant in Subjects With nAMD or DME (NCT03835884) | Aerie Pharmaceuticals | 2019-06-24 |
| One Year Trial Evaluating Safety of Ozurdex With Eylea (NCT03984110) | Texas Retina Associates | 2019-06-11 |
| Multiple Dose Safety and Efficacy of LKA651 in Patients With Diabetic Macular Edema (NCT03927690) | Novartis Pharmaceuticals | 2019-05-24 |
| Changes in Inflammatory Biomarkers Including Soluble CD14 and Hyperreflective Foci in DME Patients Treated With Aflibercept (FORESIGHT) (NCT03780361) | Hyewon Chung | 2019-05-17 |
| Diabetic Macular Edema Asian Response (DEAR) Study: Biomarkers for Response to Aflibercept in Asian Patients With Center Involving DME (NCT03197480) | Singapore National Eye Centre | 2019-04-17 |
| Long Term Safety of Cooling Anesthesia for Intravitreal Injection (NCT03956797) | Recens Medical, Inc. | 2019-04-15 |
| A Pilot Study Evaluating Photobiomodulation Therapy for Diabetic Macular Edema (NCT03866473) | Jaeb Center for Health Research | 2019-04-10 |
| The Study of Drug 601 in Patients With Diabetic Macular Edema (DME) (NCT04151407) | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | 2019-03-08 |
| Effect of Corona Virus on Intravitreal Injections (NCT05494775) | Benha University | 2019-02-01 |
| Barriers to Eye Screening for People With Diabetes in India (NCT04544553) | Lions Club International Foundation | 2019-01-24 |
| Chart Review: Drug Utilization Study in Participants Who Received Ozurdex™ (Dexamethasone Intravitreal Implant) 0.7 mg Injections for Visual Impairment Due to Diabetic Macular Edema (DME) (NCT03889444) | Allergan | 2019-01-15 |
| Exploratory Study to Investigate the Bioactivity, Ocular and Systemic Safety, Tolerability, and Pharmacokinetics Following Single and Multiple Intravitreal Administrations of KSI-301 in Subjects With wAMD, DME and RVO (NCT03790852) | Kodiak Sciences Inc | 2018-12-26 |
| Post Intravitreal Injection Topical NSAID vs. Patching (NCT03918590) | The New York Eye & Ear Infirmary | 2018-12-03 |
| Cooling Anesthesia for Intravitreal Injection (NCT03732287) | Recens Medical, Inc. | 2018-11-30 |
| Steroid vs. Anti-vascular Endothelial Growth Factor for Diabetic Macular Edema Prior to Phacoemulsification (NCT03832179) | Bay Area Retina Associates | 2018-11-15 |
| Predicting Diabetic Retinopathy From Risk Factor Data and Digital Retinal Images (NCT03694145) | Charles Drew University of Medicine and Science | 2018-10-25 |
| NOTAL-OCT V.2.5 vs Commercial OCT in AMD Patients (NCT03969303) | Notal Vision Ltd. | 2018-10-20 |
| Combination of Intravitreal Ranibizumab With or Without Micropulse Laser for the Treatment of DME (NCT03690947) | Beijing Hospital | 2018-10-01 |
| A Study to Evaluate the Safety of THR-687 in Subjects With Diabetic Macular Edema (DME) (NCT03666923) | ThromboGenics | 2018-09-17 |
| A Study to Evaluate the Efficacy and Safety of Faricimab (RO6867461) in Participants With Diabetic Macular Edema (YOSEMITE) (NCT03622580) | Hoffmann-La Roche | 2018-09-05 |
| Comparative Study to Evaluate the Efficacy and Safety of MYL-1701P and Eylea® in Subjects With Diabetic Macular Edema (DME) (NCT03610646) | Mylan Pharmaceuticals Inc | 2018-08-23 |
| Study of Efficacy and Safety of Brolucizumab vs. Aflibercept in Patients With Visual Impairment Due to Diabetic Macular Edema (NCT03481634) | Novartis Pharmaceuticals | 2018-07-23 |
| Advanced Glycation End Products Are Associated With Diabetic Macular Edema (NCT04468152) | Hacettepe University | 2018-07-07 |
| Follow up of Diabetic Macular Edema Treated by Aflibercept (Eylea®) With OCT-Angiography (NCT03783832) | Aquitania Opthalmologica | 2018-06-19 |
| Intravitreal Alfibercept for Center Involved DME Previously Managed With Intravitreal Ranibizumab (NCT03059277) | Southeast Clinical Research Associates, LLC | 2018-06-01 |