| An Energetic View on Creativity, Psychopathology and Intelligence: The Brain2Business Study (NCT05544877) | Psychiatrische Dienste Thurgau | 2022-07-19 |
| A Study of Aticaprant as Adjunctive Therapy in Adult Participants With Major Depressive Disorder (MDD) With Moderate-to-severe Anhedonia and Inadequate Response to Current Antidepressant Therapy (NCT05455684) | Janssen Research & Development, LLC | 2022-06-22 |
| Microbiotherapy in Characterized Depressive Disorder (NCT05280015) | Centre Hospitalier Universitaire de Besancon | 2022-06-08 |
| Aerobic Versus Leisure Group for Adolescents With Depression (NCT05076214) | Lund University Hospital | 2022-02-28 |
| A Randomized Control Trial Treating Depression With Yoga and Coherent Breathing Versus Walking in Veterans (NCT03489122) | VA Office of Research and Development | 2022-01-11 |
| Prospective Assessment of Cost-effectiveness and Side-effects of Depressive Patients Treated With ECT or TCA (NCT05306184) | Radboud University Medical Center | 2022-01-01 |
| The Efficacy And Safety Of Mitizodone Phosphate Tablets In The Treatment of Patient With Major Depressive Disorder (NCT04984512) | Sunshine Lake Pharma Co., Ltd. | 2021-12-14 |
| Rapid Acting TMS for Suicide Ideation in Depression (NCT05100004) | Stanford University | 2021-11-07 |
| A Standard of Care Study of Patients With Major Depressive Disorder Who Have Had an Inadequate Response to a Selective Serotonin Reuptake/Serotonin-Norepinephrine Reuptake Inhibitor Antidepressant (NCT05109195) | Janssen Research & Development, LLC | 2021-10-26 |
| Synaptic Imaging and Network Activity in Treatment Resistant Depression (NCT05870501) | King's College London | 2021-10-20 |
| Treatment of Major Depression by rTMS on Dorsolateral Prefrontal Cortex: Study of Underlying Mechanisms (NCT05121129) | Centre Hospitalier Universitaire de Besancon | 2021-10-13 |
| A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adolescents With Major Depressive Disorder Who Have an Inadequate Response to Selective Serotonin Reuptake Inhibitor (SSRI) and Psychotherapy (NCT04951609) | Janssen Research & Development, LLC | 2021-09-02 |
| Assessment of the Impact of Clinical Pharmacogenomics on Real and Potential Medication Use in Veterans (NCT04893395) | Auburn University | 2021-09-01 |
| Probiotics and the Gut Brain Axis- Do Probiotics Interact With the Vagal Nerve? (NCT04772664) | Medical University of Graz | 2021-08-16 |
| Sevoflurane for Treatment-Resistant Depression (NCT05008939) | Shanghai First Maternity and Infant Hospital | 2021-08-01 |
| Treatment of Acute Mood Depressive Episode in Borderline Personality Disorder With rTMS (NCT04870255) | Stanford University | 2021-07-20 |
| A Study to Test How Well Different Doses of BI 1569912 Are Tolerated and How Well They Work in People With Depression Who Take Anti-depressive Medication (NCT04937829) | Boehringer Ingelheim | 2021-07-20 |
| Neuro MRI Biomarkers for Treatment Navigation in Depression (NCT05701267) | Eindhoven University of Technology | 2021-07-01 |
| Precision Medicine in the Depression Treatment (NCT05616559) | Rigshospitalet, Denmark | 2021-06-15 |
| Dexmedetomidine Adjuvant Treatment for Depressed Patients Undergoing ECT (NCT04661475) | Sultan Qaboos University | 2021-06-01 |
| A Long-Term Extension Study for Participants With Treatment-resistant Major Depressive Disorder Who Are Continuing Esketamine Nasal Spray Treatment (NCT04829318) | Janssen-Cilag Ltd. | 2021-04-26 |
| Deep Brain Stimulation for Treatment Resistant Depression (NCT05716555) | Second Affiliated Hospital, Zhejiang University, School of Medicine | 2021-03-14 |
| Aerobic Group Exercise for Adolescents With Depression (NCT04695145) | Lund University Hospital | 2021-03-08 |
| Evaluate the Quality of Life and Treatment of Anxiety Symptoms of Buspirone in Patients With Depression Disorders(BASIS) (NCT04770454) | Boryung Pharmaceutical Co., Ltd | 2021-02-08 |
| Music as an Intervention to Improve Hemodynamic Tolerability of Ketamine in Depression (NCT04701866) | Douglas Mental Health University Institute | 2021-01-11 |
| Alpha-Stim AID and Major Depressive Disorder (NCT04963907) | Electromedical Products International, Inc. | 2021-01-05 |
| Web-based Self-help Intervention for Adolescents With Acute or Remitted Major Depressive Disorder (NCT04994470) | Ludwig-Maximilians - University of Munich | 2021-01-04 |
| A Study of SLS-002 (Intranasal Racemic Ketamine) in Adults With Major Depressive Disorder at Imminent Risk of Suicide (NCT04669665) | Seelos Therapeutics, Inc. | 2020-12-17 |
| Biomarkers of Depression and Treatment Response (NCT04581902) | University of California, San Francisco | 2020-12-01 |
| In-person vs. Remote Wellness Support (NCT04526067) | The University of Texas Health Science Center at San Antonio | 2020-11-24 |
| Accelerated Bilateral rTMS on Geriatric Depression (NCT04486222) | National Taiwan University Hospital | 2020-11-23 |
| A Study to Test the Effect of Different Doses of BI 1358894 and Quetiapine in People With Depression (NCT04521478) | Boehringer Ingelheim | 2020-11-20 |
| Cognitive Fitness for Depression in Older Adults (NCT04790630) | UConn Health | 2020-11-15 |
| A Comparative Study of Sage-217 Plus an Antidepressant (ADT) Versus Placebo Plus an ADT in Adults With Major Depressive Disorder (NCT04476030) | Biogen | 2020-11-09 |
| A Study to Evaluate the Benefit of Opti-Me Application to Different Treatments of MDD (NCT04148612) | ElMindA Ltd | 2020-10-06 |
| A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant and Long-term Safety Extension Treatment With Seltorexant (NCT04533529) | Janssen Research & Development, LLC | 2020-09-16 |
| A Study of Seltorexant as Adjunctive Therapy to Antidepressants in Adult and Elderly Participants With Major Depressive Disorder With Insomnia Symptoms Who Have Responded Inadequately to Antidepressant Therapy (NCT04532749) | Janssen Research & Development, LLC | 2020-09-15 |
| NESBID: Neuro-Stimulation of the Brain in Depression (NCT04159012) | University of Alberta | 2020-09-01 |
| A Long-term Comparison of Esketamine Nasal Spray Versus Quetiapine Extended Release, Both in Combination With a Selective Serotonin Reuptake Inhibitor/Serotonin-Norepinephrine Reuptake Inhibitor, in Participants With Treatment Resistant Major Depressive Disorder (NCT04338321) | Janssen-Cilag International NV | 2020-08-21 |
| Simvastatin add-on Treatment to Standard Antidepressant Therapy in Patients With Comorbid Obesity and Major Depression (NCT04301271) | Charite University, Berlin, Germany | 2020-08-13 |
| Using Repetitive Transcranial Magnetic Stimulation to Study the Role of Frontostriatal Circuit in Major Depressive Disorder (NCT05212636) | National Cheng-Kung University Hospital | 2020-08-01 |
| Personalized Escitalopram Dosing in Patients With Depression (NCT05210140) | University of Belgrade | 2020-07-16 |
| A Study of Oral Seltorexant as an add-on Medication to an Antidepressant on On-road Driving Performance in Participants With Major Depressive Disorder (NCT04451187) | Janssen Research & Development, LLC | 2020-07-16 |
| Personalized Sertraline Dosing in Patients With Depression (NCT05210153) | University of Belgrade | 2020-07-16 |
| A Study to Describe Routine Treatment Pathways in Participants With Major Depression and Active Suicidal Ideation With Intent in Italy (NCT04463108) | Janssen-Cilag S.p.A. | 2020-06-23 |
| A Home-based Study Using Mobile Technology to Test Whether BI 1358894 is Effective in People With Depression (NCT04423757) | Boehringer Ingelheim | 2020-06-22 |
| A Study to Evaluate the Efficacy of Sage-217 in the Treatment of Adult Participants With Major Depressive Disorder (MDD) (NCT04442490) | Biogen | 2020-05-12 |
| A Study of Psilocybin for Major Depressive Disorder (MDD) (NCT03866174) | Usona Institute | 2020-01-23 |
| ICBT for Depression - A Factorial Investigation of Kinds of Therapist Support and Self-/Expert-selected Content (NCT04260750) | Linkoeping University | 2020-01-13 |
| Efficacy of Deep Anaesthesia With Isoflurane as a Fast-response Antidepressant Agent (NCT04171193) | University of Sao Paulo | 2019-12-01 |
| Antidepressant Decision Aid for Major Depressive Disorder Patients (NCT04761757) | University of Malaya | 2019-12-01 |
| Effects of Nutrients Supplementation in Antidepressant Treated Depressive Disorder Patients (NCT04179006) | National Cheng-Kung University Hospital | 2019-11-14 |
| Optimal Electrical Stimulus During Electroconvulsive Therapy (NCT04057378) | Region Örebro County | 2019-10-30 |
| Major Depressive Disorder: Early Prediction of Non-response to Antidepressant Therapy Via a Mobile Digital Scale (NCT03872492) | Ad scientiam | 2019-10-17 |
| Antidepressant Trial With P2X7 Antagonist JNJ-54175446 (NCT04116606) | CCTU-Core | 2019-09-12 |
| Effectiveness of IPT-G in Major Depression (NCT04015206) | Hospital de Clinicas de Porto Alegre | 2019-08-25 |
| Study of Rapastinel as Monotherapy in Major Depressive Disorder (MDD) (NCT03855865) | Naurex, Inc, an affiliate of Allergan plc | 2019-07-01 |
| Ketamine for Mood Disorders With Suicidal Ideation (NCT04099771) | The Miriam Hospital | 2019-07-01 |
| Patient Outcomes Reporting for Timely Assessments of Life With Depression: PORTAL-Depression (NCT03832283) | University of Chicago | 2019-05-01 |
| Nitrous Oxide for Major Depressive Disorder (NCT03932825) | Lingjiang Li | 2019-04-01 |
| The Effect of Probiotic Supplementation on the Mental Status, Inflammation, and Intestinal Barrier in Major Depressive Disorder Patients Using Gluten-free or Gluten-containing Diet (NCT03877393) | Medical University of Lublin | 2019-04-01 |
| A Study in People With Depression to Test the Effects of BI 1358894 on Parts of the Brain That Are Involved in Emotions (NCT03854578) | Boehringer Ingelheim | 2019-03-12 |
| Clinical, Neurocognitive, and Emotional Effects of Psilocybin in Depressed Patients - Proof of Concept (NCT03715127) | University of Zurich | 2019-03-11 |
| Vortioxetine for Treatment of Depressive Mood and Alcohol Use (NCT04498897) | Hanyang University Seoul Hospital | 2019-01-25 |
| Triple Chronotherapy in Adolescents (NCT03679962) | Billings Clinic | 2019-01-25 |
| Coil Positioning in Navigated Transcranial Magnetic Stimulation Feasibility in Depression Patients Trial (NCT03795051) | Magstim | 2019-01-09 |
| Psilocybin vs Escitalopram for Major Depressive Disorder: Comparative Mechanisms (NCT03429075) | Imperial College London | 2019-01-07 |
| Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response, Pilot Trial (NCT03367533) | Yale University | 2018-11-29 |
| Rescuing the Ruminating Brain: Identifying Biomarkers of Rumination and Mindfulness Through Concurrent EEG and Functional Magnetic Resonance Imaging (fMRI) Studies of Schizophrenia and Depression (NCT03758495) | VA Office of Research and Development | 2018-11-01 |
| Study of Rapastinel as Monotherapy in Patients With Major Depressive Disorder (MDD) (NCT03675776) | Naurex, Inc, an affiliate of Allergan plc | 2018-10-30 |
| Ketamine Versus Electroconvulsive Therapy in Depression (NCT03674671) | University of Ottawa | 2018-10-29 |
| Ketamine for Treatment Resistant MDD (NCT04021433) | Hadassah Medical Organization | 2018-09-01 |
| Olfactory Training and Emotional State (NCT03605524) | University Hospital, Tours | 2018-08-28 |
| Study of Adjunctive or Monotherapy Rapastinel Treatment in Patients With Major Depressive Disorder (MDD) (NCT03668600) | Naurex, Inc, an affiliate of Allergan plc | 2018-08-23 |
| Study of Monotherapy Rapastinel in the Prevention of Relapse in Patients With Major Depressive Disorder (MDD) (NCT03614156) | Naurex, Inc, an affiliate of Allergan plc | 2018-08-02 |
| Resting-state Functional Connectivity Throughout a Course of iTBS in Major Depression (NCT03944213) | University Hospital, Bonn | 2018-07-23 |
| A Study to Explore the Efficacy of JNJ-67953964 in the Treatment of Depression (NCT03559192) | Janssen Research & Development, LLC | 2018-07-16 |
| Study of Rapastinel as Monotherapy in Patients With MDD (NCT03560518) | Naurex, Inc, an affiliate of Allergan plc | 2018-06-15 |
| Pharmacogenetics Informed Tricyclic Antidepressant Dosing (PITA) (NCT03548675) | Radboud University Medical Center | 2018-05-23 |
| Safety, Tolerability, PK Profile, and Symptom Response of a 7-Day Dosing With 25 mg or 50 mg Daily of REL-1017 in MDD (NCT03051256) | Relmada Therapeutics, Inc. | 2018-05-11 |
| Does Nurse Semi Structured Interview Added to a rTMS Improve Patients With Major Depressive Disorder? (NCT03436823) | Rennes University Hospital | 2018-03-19 |
| Sleep, Wake and Light Therapy for Depression (NCT03405493) | King's College London | 2018-01-18 |
| A Study to Investigate the Antidepressant Mechanism-of-action of JNJ-42847922 in Participants With Major Depressive Disorder (NCT03374475) | Janssen Research & Development, LLC | 2018-01-05 |
| Attention Bias Modification Treatment for Young Adults With Major Depressive Disorder (NCT03971903) | Hunan Normal University | 2017-12-24 |
| A Study of Rapastinel for Rapid Treatment of Depression and Suicidality in Major Depressive Disorder (NCT03352453) | Naurex, Inc, an affiliate of Allergan plc | 2017-12-15 |
| A Study to Compare the Efficacy, Safety, and Tolerability of JNJ-42847922 Versus Quetiapine Extended-Release as Adjunctive Therapy to Antidepressants in Adult Participants With Major Depressive Disorder Who Have Responded Inadequately to Antidepressant Therapy (NCT03321526) | Janssen Research & Development, LLC | 2017-12-12 |
| Adaptive Design Study of NEST sTMS in Subjects With Major Depressive Disorder (NCT03288714) | Wave Neuroscience | 2017-11-27 |
| Neurobehavioral Mechanisms of Emotion Regulation in Depression Across the Adult Lifespan (NCT03207503) | Duke University | 2017-10-10 |
| Stepped Care AiTBS 2 Depression Study (Ghent) (NCT03288675) | University Hospital, Ghent | 2017-10-05 |
| Study to Evaluate the Efficacy and Safety of 3 Fixed Doses of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Pediatric Participants Assessed to be at Imminent Risk for Suicide (NCT03185819) | Janssen Research & Development, LLC | 2017-10-05 |
| Molecular Imaging of Brain Inflammation in Depressive Disorders (NCT02983318) | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2017-08-28 |
| Neuropsychological Factors Associated With Vulnerability to Suicidal Behavior in Depressed Elderly Patients (NCT02737540) | Centre Hospitalier Universitaire de Nīmes | 2017-08-16 |
| Exploring Effects of Electroconvulsive Therapy on the Human Brain in Depression - The Danish ECT/MRI Study (NCT03040388) | University of Copenhagen | 2017-08-09 |
| Feasibility of a Technology-Based Treatment Support System (NCT03121937) | Northwestern University | 2017-08-01 |
| 54135419SUI3002: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for Suicide (NCT03097133) | Janssen Research & Development, LLC | 2017-06-15 |
| 54135419SUI3001: A Study to Evaluate the Efficacy and Safety of Intranasal Esketamine in Addition to Comprehensive Standard of Care for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Adult Participants Assessed to be at Imminent Risk for Suicide (NCT03039192) | Janssen Research & Development, LLC | 2017-06-09 |
| A Study to Investigate the Safety, Tolerability and Pharmacokinetics of SUVN-911 in Healthy Subjects (NCT03155503) | Suven Life Sciences Limited | 2017-05-22 |
| Promote Access to Stop Suicide: Comparison of Follow up Services for Youth at Risk for Suicide (NCT03016572) | The Cleveland Clinic | 2017-05-04 |
| Continuation With Vortioxetine in Child and Adolescent Patients With Major Depressive Disorder (MDD) From 7 to 17 Years of Age (NCT03108625) | H. Lundbeck A/S | 2017-03-01 |
| Stepped Care for Depression in Heart Failure (NCT02997865) | Washington University School of Medicine | 2017-02-17 |