| A Study of LW231 to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics in Healthy Volunteers and Participants With Chronic Hepatitis B Virus Infection (NCT06311734) | Shanghai Longwood Biopharmaceuticals Co., Ltd. | 2022-06-21 |
| The Effectiveness and Safety of TMF in the Treatment of Chronic Hepatitis B Patients With Normal ALT. (NCT05797714) | Ruijin Hospital | 2022-06-08 |
| Risk Factors for Hepatic Inflammation, Fibrosis and Prognosis in Patients With CHB and NAFLD (NCT05766449) | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 2022-06-01 |
| A Pharmacokinetic Study to Evaluate the Drug Interaction Between HRS5091 and Probe Drugs in Healthy Volunteers (NCT05273775) | Jiangsu HengRui Medicine Co., Ltd. | 2022-04-29 |
| From Fungus to Virus, Investigating the Safety and Efficacy of Terbinafine in Chronic Hepatitis B Patients (NCT06295328) | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 2022-04-13 |
| Performance of Novel Simplified Score for Chronic Hepatitis B Treatment Eligibility in Thailand (NCT05295914) | Mahidol University | 2022-04-10 |
| Metabolic Associated Fatty Liver Disease and Pancreatic Steatosis in Obese Versus Lean Chronic Hepatitis B Patients (NCT07175688) | Tanta University | 2022-04-10 |
| Ethnobridging Study in Healthy Volunteers, Chinese and Japanese Subjects (NCT05298332) | Antios Therapeutics, Inc | 2022-03-29 |
| A Follow-up Study of Peginterferon Alfa-2b Combined With TDF in Patients With Chronic Hepatitis B (NCT06707922) | Xiamen Amoytop Biotech Co., Ltd. | 2022-03-18 |
| Clinical Study to Evaluate the Pharmacokinetics, Safety and Tolerability of CKD-388(2) in Healthy Subjects (NCT05189288) | Chong Kun Dang Pharmaceutical | 2022-01-14 |
| A Study to Assess the Efficacy and Safety of Burfiralimab(hzVSF-v13) and OAD (Oral Antiviral Drug) (NCT05808335) | ImmuneMed, Inc. | 2022-01-11 |
| Effects of Empagliflozin on Fibrosis and Cirrhosis in Chronic Hepatitis B Patients (NCT05147090) | The University of Hong Kong | 2022-01-02 |
| The Study on Clinical Outcome and Treatment Optimization of Chronic Hepatitis B Patients With Hypoviremia (NCT05357183) | Beijing Ditan Hospital | 2022-01-01 |
| The Study on Optimal Treatment and Clinical Outcome of Chronic Hepatitis B Patients With Inactive Hypoviremia (NCT05357235) | Beijing Ditan Hospital | 2022-01-01 |
| A Study of LP-128 Capsules in Healthy Subjects (NCT05130567) | Guangzhou Lupeng Pharmaceutical Company LTD. | 2021-11-19 |
| Open-Label Study of AB-729, Nucleos(t)Ide Analogue and Pegylated Interferon Alfa-2a in Subjects With Chronic Hepatitis B Infection (NCT04980482) | Arbutus Biopharma Corporation | 2021-10-29 |
| A Study to Evaluate the Antiviral Activity and Safety of HH-003 Injection in Subjects With HBeAg-Negative Chronic Hepatitis B Treated With Nucleos(t)Ide Reverse Transcriptase Inhibitors (NCT05839639) | Huahui Health | 2021-10-09 |
| Study to Evaluate the Tolerability, Safety, Pharmacokinetics and Pharmacodynamics of TQA3810 Tablets (NCT06431438) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2021-10-01 |
| Study on Clinical Program Optimization of Inactive Hepatitis B Surface Antigen (HBsAg) Carriers (IHCs) (NCT05457920) | Henan Provincial People's Hospital | 2021-10-01 |
| A Study of ALG-020572 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single Doses in Healthy Volunteers and Multiple Doses in CHB Subjects (NCT05001022) | Aligos Therapeutics | 2021-09-25 |
| Study to Evaluate the Safety and Efficacy of Selgantolimod (SLGN)-Containing Combination Therapies for the Treatment of Chronic Hepatitis B (CHB) (NCT04891770) | Gilead Sciences | 2021-08-14 |
| A Single and Repeated Dose Escalation of RBD1016 in Subjects with Chronic Hepatitis B Virus (HBV) Infection (NCT05017116) | Suzhou Ribo Life Science Co. Ltd. | 2021-08-09 |
| The Efficacy and Safety of 12-week SOF/VEL Regimen Combined With Prophylactic Use of TAF for Treatment-naïve Genotype 1-6 HCV/HBV Co-infection Adult Patients With or Without Compensated Cirrhosis in China (NCT04997564) | Peking University First Hospital | 2021-08-01 |
| COIN-B: COntrolled Interruption of Nucleos(t)Ide Analogue Treatment in Chronic Hepatitis B Infections (NCT04779970) | University Hospital, Antwerp | 2021-07-28 |
| Effort to Narrow the Gap Between in Accordance With Guidelines and Consent to Treat CHB Population in East of China (NCT04980664) | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 2021-07-01 |
| Safety and Efficacy of TAF to Prevent MTCT of HBV in Middle/Late Pregnancies With High HBV DNA Load (NCT05466071) | Xingfei Pan | 2021-07-01 |
| Tenofovir Alafenamide Switching Therapy in Kidney or Liver Transplant Recipients With Chronic HBV Infection (NCT05410496) | Taichung Veterans General Hospital | 2021-06-22 |
| Stopping Antiviral Treatment in Chronic Hepatitis B (NCT04431245) | The University of Hong Kong | 2021-06-01 |
| A Study Evaluating Treatment Regimens Containing Vebicorvir (ABI-H0731) in Participants With Chronic Hepatitis B Infection (NCT04820686) | Assembly Biosciences | 2021-05-07 |
| Study of Tenofovir Alafenamide in HBV-Infected Pregnant Women (NCT05853718) | First People's Hospital of Hangzhou | 2021-05-06 |
| Efficacy and Safety of TAF for 48 Weeks in HBeAg Positive CHB Patients (NCT04864366) | Huashan Hospital | 2021-04-30 |
| Tenofovir Alafenamide to Prevent Perinatal Transmission of Hepatitis B (NCT04850950) | The First Affiliated Hospital of Zhengzhou University | 2021-04-26 |
| Regression of Liver Fibrosis by Tenofovir Alafenamide (TAF) (NCT04939441) | Jidong Jia | 2021-04-20 |
| Plasma Purification and Chronic Hepatitis B (NCT04518553) | Shanghai Pudong Hospital | 2021-03-23 |
| A Study Evaluating ABI-H0731-containing Regimens in Chinese Participants With Chronic Hepatitis B Virus Infection (NCT04781647) | Assembly Biosciences | 2021-02-18 |
| Activity of NCO-48 Fumarate in Treatment-Naive Adults With Chronic Hepatitis B (NCT04629976) | Nucorion Pharmaceuticals, Inc. | 2021-01-12 |
| GLS4/RTV and TAF Drug-drug Interaction (NCT04551261) | Sunshine Lake Pharma Co., Ltd. | 2021-01-10 |
| Prevalence of Occult Hepatitis B Virus Infection（OBI） in Subjects With Chronic Hepatitis B（CHB） Family History (NCT04672915) | First Affiliated Hospital Xi'an Jiaotong University | 2020-12-21 |
| LDT Combined With TDF to Improve EGFR Decreasing in Patients With Chronic Hepatitis B Treated With TDF (NCT04643990) | Third Affiliated Hospital, Sun Yat-Sen University | 2020-12-01 |
| A Study to Evaluate the Mass Balance Absorption and AME of VBR (NCT04637139) | Assembly Biosciences | 2020-12-01 |
| TDF Combined With LDT for the Treatment of HBeAg-positive Hepatitis B Patients With Poor Response to TDF for 12 Months (NCT04650828) | Third Affiliated Hospital, Sun Yat-Sen University | 2020-12-01 |
| A Study Evaluating Treatment Intensification With ABI-H0731 in Participants With Chronic Hepatitis B Infection on Nucleos(t)Ide Reverse Transcriptase Inhibitors (NCT04454567) | Assembly Biosciences | 2020-11-11 |
| A Study of ALG-000184 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single and Multiple Doses in Healthy Volunteers and CHB Subjects (NCT04536337) | Aligos Therapeutics | 2020-10-22 |
| Chronic Hepatitis b Patients Switch to tAf After Discontinuation of Nucleoside Analogue (NCT04496882) | National Taiwan University Hospital | 2020-09-09 |
| Long-term Outcomes of Anti-viral Therapies in Patients With Chronic Viral Hepatitis B (NCT04896255) | Huashan Hospital | 2020-09-09 |
| A Study of ABI-H2158-containing Regimens in Participants With Chronic Hepatitis B Virus Infection (NCT04398134) | Assembly Biosciences | 2020-08-28 |
| A Study of ALG-010133 Drug to Evaluate Safety, Tolerability, Pharmacokinetics and Pharmacodynamics After Single and Multiple Doses in Healthy Volunteers and CHB Subjects (NCT04485663) | Aligos Therapeutics | 2020-08-17 |
| The Efficacy and Safety of TAF vs Other NAs in Patients With LVL (NCT04501224) | Third Affiliated Hospital, Sun Yat-Sen University | 2020-08-03 |
| Serum Regucalcin Level and Chronic Hepatitis B (NCT05435599) | Konya Meram State Hospital | 2020-08-01 |
| Efficacy and Safety of TAF in Pregnant Women With Chronic Hepatitis B Infection (NCT04507607) | Third Affiliated Hospital, Sun Yat-Sen University | 2020-08-01 |
| A Phase I Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Food Effect of Oral HRS5091 in Healthy Subjects and Chronic Hepatitis B Patients (NCT04480294) | Jiangsu HengRui Medicine Co., Ltd. | 2020-07-28 |
| A Phase II Study of Subcutaneously Injected PD-L1 Antibody ASC22 in Chronic Hepatitis B Patients (NCT04465890) | Ascletis Pharmaceuticals Co., Ltd. | 2020-07-17 |
| Biomarkers Guided Stopping NAs Treatment (NCT04519359) | Nanfang Hospital, Southern Medical University | 2020-07-06 |
| Study of VIR-2218 With or Without Pegylated Interferon Alpha-2a for Treatment of Chronic Hepatitis B Virus Infection (NCT04412863) | Vir Biotechnology, Inc. | 2020-07-03 |
| Study of VIR-3434 in Healthy Volunteers and Patients With Chronic Hepatitis B Virus Infection (NCT04423393) | Vir Biotechnology, Inc. | 2020-05-26 |
| A Study to Assess Safety, Tolerability, and Pharmacokinetics of ABI-H3733 in Healthy Adults (NCT04271592) | Assembly Biosciences | 2020-05-17 |
| The Effectiveness and Safety of Tenofovir Alafenamide in the Treatment of Chronic Hepatitis B Patients With Mildly Elevated Alanine Aminotransferase and Significant Liver Injury. (NCT04674423) | National Cheng-Kung University Hospital | 2020-05-14 |
| A Cohort Study on Long-term Clinical Outcomes of Antiviral Therapy in Patients With Chronic Hepatitis B and Cirrhosis (NCT04301908) | Beijing Ditan Hospital | 2020-04-01 |
| A Study to Investigate the Safety, Tolerability, Pharmacokinetics of Single and Multiple Doses of Hepenofovir Fumarate Tablets in Healthy Volunteers. (NCT04277897) | Xi'an Xintong Pharmaceutical Research Co.,Ltd. | 2020-03-15 |
| Metformin as Add-on to the Standard Therapy in Patients With Chronic Hepatitis B (NCT04182321) | Fu-Sheng Wang | 2020-03-13 |
| Clinical Effects of Ganshuang Combined TDF to Treat CHB and NAFLD (NCT05523648) | Sichuan Leshan Traditional Chinese Medicine Hospital | 2020-01-05 |
| Combination of ETV, TQ-A3334 and TQ-B2450 for CHB (Neptune Study) (NCT04202653) | Tongji Hospital | 2020-01-01 |
| A Study of Peginterferon Alfa-2b Combined With TDF in Patients With Chronic Hepatitis B (NCT04846491) | Xiamen Amoytop Biotech Co., Ltd. | 2019-12-04 |
| Spirulina (FEM-102) Supplement to Chronic Hepatitis B Patients (NCT04718831) | Taipei Medical University WanFang Hospital | 2019-10-29 |
| Study of Nitazoxanide Compared to Placebo in Subjects With HBeAG-Negative Chronic Hepatitis B (NCT03905655) | Romark Laboratories L.C. | 2019-10-22 |
| A Study to Assess CYP3A4 Modulator, Oral Contraceptive, and pH Modifier Drug Interactions for ABI-H2158 in Healthy Adults (NCT04142762) | Assembly Biosciences | 2019-10-18 |
| A Study to Assess the Relative Bioavailability and Food Effect of ABI-H2158 in Healthy Adults (NCT04083716) | Assembly Biosciences | 2019-09-06 |
| An Study to Evaluate Safety and Efficacy of QL-007 Tablets in Combination With Tenofovir in Naive Patients With Chronic Hepatitis b (NCT04157699) | Qilu Pharmaceutical Co., Ltd. | 2019-07-26 |
| An Study to Evaluate Safety and Efficacy of QL-007 Tablets in Combination With Entecavir or Tenofovir in Patients With Chronic Hepatitis b Who Have Received Nucleoside (Acid) Therapy (NCT04157257) | Qilu Pharmaceutical Co., Ltd. | 2019-07-26 |
| A Prospective Study to Evaluate Peginterferon in Reducing the Incidence of HCC in CHB Patients (NCT05671315) | Qing XIe | 2019-07-03 |
| Effectiveness of TAF in Reducing Clinical Events in CHB Patients Beyond Treatment Indications by Current Guidelines (NCT03753074) | Young-Suk Lim | 2019-02-18 |
| Hepatitis B Immune Globulin (HBIg) to Restore Immune Control in People With Chronic Hepatitis B (NCT03575208) | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | 2019-02-13 |
| Halting Nucleoside Analogues in Chronic Hepatitis B (NCT04102176) | Seng Gee Lim | 2019-01-29 |
| TAF Real World Study for Universal Effectiveness (NCT03752658) | Tongji Hospital | 2019-01-25 |
| Three Types of Nucleotide/Nucleoside Analogues Therapy in Patients With Chronic Hepatitis b (NCT04195074) | Third Affiliated Hospital, Sun Yat-Sen University | 2019-01-01 |
| The Optimizing Treatment of Peginterferon Alpha in Chronic Hepatitis B Patients With Low Level HBsAg (NCT03801538) | Third Affiliated Hospital, Sun Yat-Sen University | 2019-01-01 |
| A Study of ABI-H0731 + Nucleos(t)Ide as Finite Treatment for Chronic Hepatitis B Patients (NCT03780543) | Assembly Biosciences | 2018-12-20 |
| Bioequivalence Study of Entecavir Tablets and Baraclude® Under Fasting Condition in Chinese Healthy Volunteers (NCT03847246) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | 2018-12-04 |
| Cessation of Long Term NAs vs. Keeping on NAs Among CHB Patients (CNAVK) (NCT03792919) | Humanity & Health Medical Group Limited | 2018-12-01 |
| Effect of Serum Vitamin D Level on the Efficacy of Peg-interferon Treatment in CHB (NCT05753280) | Third Affiliated Hospital, Sun Yat-Sen University | 2018-12-01 |
| Optimal Treatment for Poor Efficacy of Entecavir in Chronic Hepatitis B Patients (NCT03733652) | Third Affiliated Hospital, Sun Yat-Sen University | 2018-11-15 |
| Study of VIR-2218 in Healthy Subjects and Patients With Chronic Hepatitis B (NCT03672188) | Vir Biotechnology, Inc. | 2018-11-14 |
| A Study of ABI-H2158 in Healthy Volunteers and Patients With Chronic Hepatitis B (NCT03714152) | Assembly Biosciences | 2018-11-13 |
| Evaluation of Antiviral Indications on Chronic HBV Infection With Different Transaminase Levels (NCT03740789) | First Affiliated Hospital Xi'an Jiaotong University | 2018-10-24 |
| A Study to Investigate the Safety, Efficacy and PK of Multiple Doses of QL-007 in Chronic Hepatitis B Patients in CHINA (NCT03770624) | Qilu Pharmaceutical Co., Ltd. | 2018-10-16 |
| Clinical Study to Evaluate the Safety and Efficacy of Switching to Tenofovir Disoproxil From Tenofovir Disoproxil Fumarate in Patients With Chronic Hepatitis B (NCT05286346) | Samjin Pharmaceutical Co., Ltd. | 2018-10-12 |
| Clinical Trial to Evaluate the Efficacy and Safety of TenofoBell® Tablet in Chronic Hepatitis B Patients (NCT04539652) | Chong Kun Dang Pharmaceutical | 2018-09-20 |
| Study to Evaluate the Safety, Tolerability, and Antiviral Activity of Selgantolimod (Formerly GS-9688) in Viremic Adult Participants With Chronic Hepatitis B (CHB) Who Are Not Currently on Treatment (NCT03615066) | Gilead Sciences | 2018-08-28 |
| A Randomized, Placebo-controlled Trial of Antroquinonol in Patients With Chronic Hepatitis B (NCT04112147) | Cheng-Chung Wei | 2018-08-10 |
| Treatment Efficacy and Safety of TDF-TAF Switch Study in South Korea (NCT03559790) | The Catholic University of Korea | 2018-07-18 |
| APG-1387 Study of Safety, Tolerability ,PK/PD in Patients With Chronic Hepatitis B (NCT03585322) | Ascentage Pharma Group Inc. | 2018-07-04 |
| Prediction System of Clinical Endpoint Events for Chronic Hepatitis B Patients (NCT03777969) | Beijing Friendship Hospital | 2018-06-29 |
| A Drug-drug Interaction (DDI) Study of Morphothiadine Mesilate/Ritonavir in Healthy Subjects (NCT03662568) | Sunshine Lake Pharma Co., Ltd. | 2018-06-26 |
| A Study Evaluating ABI-H0731 as Adjunctive Therapy in Participants With Chronic Hepatitis B Infection (NCT03576066) | Assembly Biosciences | 2018-06-11 |
| Cohort Study of Efficacy and Safety of Interferon Intermittent Treatment of Chronic Hepatitis B (NCT04028856) | Beijing Ditan Hospital | 2018-06-01 |
| Safety, Tolerability and Antiviral Activity of Selgantolimod in Virally-Suppressed Participants With Chronic Hepatitis B (NCT03491553) | Gilead Sciences | 2018-04-06 |
| A Study of Orally Administered JNJ-440 to Evaluate the Safety, Tolerability, and Pharmacokinetics After Single Ascending Doses Including Food Effect Evaluation; After Multi-Day Dosing in Healthy Participants; and After Multiple (Ascending) Doses in Participants With Chronic Hepatitis B (NCT03439488) | Alios Biopharma Inc. | 2018-03-26 |
| Study to Evaluate the Safety and Antiviral Activity of Inarigivir Soproxil (Formerly: GS-9992) Plus Tenofovir Alafenamide (TAF) for 12 Weeks in Adults With Chronic Hepatitis B (CHB) (NCT03434353) | Gilead Sciences | 2018-02-28 |
| A Real-World Study of Pegylated Interferon In Nucleoside-treated Patients With Chronic Hepatitis B (NCT03357822) | Tongji Hospital | 2018-01-25 |
| Correlation Between Virus and Biochemical Characteristics and Liver Histological Damage in Untreated Chronic HBV Infection (NCT04032275) | Beijing Ditan Hospital | 2018-01-01 |