| MRI Screening Versus SYMptom-directed Surveillance for Brain Metastases Among Patients with Triple Negative or HER2+ MBC (NCT03881605) | Sunnybrook Health Sciences Centre | 2018-11-08 |
| Dendritic Cell Therapy for Brain Metastases From Breast- or Lung Cancer (NCT03638765) | Northwest Biotherapeutics | 2018-11-01 |
| First Line Treatment in EGFR Mutation Positive Advanced NSCLC Patients With Central Nervous System (CNS) Metastases (NCT03653546) | Alpha Biopharma (Jiangsu) Co., Ltd. | 2018-10-29 |
| CBF and NCF Changes With Brain Radiation (NCT03606421) | University Health Network, Toronto | 2018-10-01 |
| The Impact of Neurocognitive Function in Patients With Multiple Brain Metastases Receiving Whole Brain Radiation Therapy (NCT03626818) | Guangdong Association of Clinical Trials | 2018-08-01 |
| A Dose Escalation Trial of Five Fraction Stereotactic Radiation Therapy for Brain Metastases (NCT03412812) | University of Alabama at Birmingham | 2018-07-30 |
| A Study to Determine the Efficiency For Brain Metastasis NSCLC Patients Treated With Icotinib Alone or Combined With Radiation Therapy (NCT04058704) | Betta Pharmaceuticals Co., Ltd. | 2018-07-20 |
| E6201 Plus Dabrafenib for the Treatment of Metastatic Melanoma Central Nervous System Metastases (CNS) (NCT03332589) | Spirita Oncology, LLC | 2018-07-02 |
| Vemurafenib Plus Cobimetinib After Radiosurgery in Patients With BRAF-mutant Melanoma Brain Metastases (NCT03430947) | Technische Universität Dresden | 2018-07-01 |
| Evaluation of Safety and Efficacy of Patients With Four and More Symptomatic Brain Metastases of Melanoma (NCT03728465) | University Hospital Tuebingen | 2018-04-10 |
| LIFE - Lung Cancer, Immunotherapy, Frailty, Effect (NCT03870464) | University of Southern Denmark | 2018-04-01 |
| Pre-operative Stereotactic Radiosurgery Followed by Resection for Patients With Brain Metastases (NCT03398694) | Indiana University | 2018-03-26 |
| A Study of Neoadjuvant Stereotactic Radiosurgery for Large Brain Metastases (NCT03368625) | University Health Network, Toronto | 2018-03-19 |
| Stereotactic Radiation in Patients With Small Cell Lung Cancer and 1-10 Brain Metastases (NCT03391362) | Brigham and Women's Hospital | 2018-02-23 |
| Concurrent Dabrafenib + Trametinib With Sterotactic Radiation in BRAF Mutation-Positive Malignant Melanoma and Brain Metastases (NCT02974803) | Canadian Cancer Trials Group | 2018-02-09 |
| Cyberknife Radiosurgery for Patients With Brain Metastases Diagnosed With Either SPACE or MPRAGE Sequence (NCT03303365) | Juergen Debus | 2018-02-01 |
| Radiation Therapy With Combination Immunotherapy for Relapsed/Refractory Metastatic Melanoma (NCT03297463) | Masonic Cancer Center, University of Minnesota | 2018-01-31 |
| Protocol for Evaluating a Planning Algorithm for Gamma Knife Radiosurgery (NCT03520829) | Assistance Publique Hopitaux De Marseille | 2018-01-10 |
| Brain Metastases in Norway - A Prospective Cohort Study (NCT03346655) | Oslo University Hospital | 2018-01-01 |
| Phase I Study of Fractionated Stereotactic Radiation Therapy (NCT03726359) | Albert Einstein College of Medicine | 2017-12-25 |
| Hippocampus-sparing WBRT and Simultaneous Integrated Boost for Multiple Brain Metastases From NSCLC (NCT03366376) | Samsung Medical Center | 2017-12-11 |
| Role of Hyperpolarized 13C-Pyruvate MR Spectroscopy in Patients With Intracranial Metastasis Treated With (SRS) (NCT03324360) | Sunnybrook Health Sciences Centre | 2017-12-06 |
| Neurocognitive Decline in Patients With Brain Metastases (NCT03508752) | University of Texas Southwestern Medical Center | 2017-12-05 |
| Apatinib Plus Radiotherapy for Patients With Brain Metastases From Non-small-cell Lung Cancer (NCT03356600) | Shanxi Province Cancer Hospital | 2017-12-01 |
| Whole Brain Radiation Therapy Alone vs. Radiosurgery for SCLC Patients With 1-10 Brain Metastases (NCT03297788) | Juergen Debus | 2017-12-01 |
| Short Course Radiation Therapy in Palliative Treatment of Brain Metastases (NCT03525301) | IRCCS Azienda Ospedaliero-Universitaria di Bologna | 2017-11-08 |
| Pilot Phase 2 Study Whole Brain Radiation Therapy With Simultaneous Integrated Boost for Patients With Brain Metastases (NCT03189381) | Indiana University | 2017-09-21 |
| Glyburide vs Placebo as Prophylaxis Against Cerebral Edema in Patients Receiving Radiosurgery for Brain Metastases (RAD 1502/UAB 1593) (NCT02460874) | University of Alabama at Birmingham | 2017-08-16 |
| Neurocognitive Functioning With Genu-Sparing Whole Brain Radiation Therapy for Brain Metastases (NCT03223922) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2017-07-19 |
| Dose Escalation Trial of Neoadjuvant Radiosurgery for the Treatment of Metastatic Brain Tumors (NCT03163368) | Cedars-Sinai Medical Center | 2017-05-09 |
| A Study of the Gene Mutation Status in Cerebrospinal Fluid, Blood and Tumor Tissue of Non-small Cell Lung Cancer Patients With Brain Metastases (NCT03257735) | Sun Yat-sen University | 2017-05-01 |
| Hippocampal Sparing Whole Brain Radiation Versus Stereotactic Radiation in Patients With 5-20 Brain Metastases: A Phase III, Randomized Trial (NCT03075072) | Dana-Farber Cancer Institute | 2017-04-10 |
| Memory Preservation of Hippocampal Avoidance Whole Brain Radiotherapy (NCT03247127) | Kaohsiung Medical University Chung-Ho Memorial Hospital | 2017-03-27 |
| Re-craniotomy and Complications After Elective Neurosurgery (NCT03910556) | Chiang Mai University | 2017-01-01 |
| Elective Simultaneous Modulated Accelerated Brain Radiation Therapy for NSCLCs With Limited Brain Metastases (NCT03414944) | Shandong Cancer Hospital and Institute | 2016-12-02 |
| Open Label, Prospective Study to Investigate Efficacy and Safety of AZD9291 in BM From NSCLC Patients With EGFR T790M (NCT02972333) | Shandong Cancer Hospital and Institute | 2016-12-01 |
| Pembrolizumab In Central Nervous System Metastases (NCT02886585) | Massachusetts General Hospital | 2016-10-01 |
| Hippocampal Sparing Whole Brain Radiotherapy vs Conventional Whole Brain Radiotherapy in Patients With Brain Metastases (NCT02147028) | University College, London | 2016-08-03 |
| nTMS for Motor Mapping of Rolandic Lesions (NCT02879682) | Technical University of Munich | 2016-08-01 |
| Corticosteroids + Bevacizumab vs. Corticosteroids + Placebo (BEST) for Radionecrosis After Radiosurgery for Brain Metastases (NCT02490878) | Alliance for Clinical Trials in Oncology | 2016-04-01 |
| Neurocognitive Impact and Dose-Effect Relationship of Hippocampal Avoidance During Whole Brain Radiotherapy Plus Simultaneous Integrated Boost - A Prospective Follow-up Study (NCT03223675) | Chang Gung Memorial Hospital | 2016-04-01 |
| 64-Cu Labeled Brain PET/MRI for MM-302 in Advanced HER2+ Cancers With Brain Mets (NCT02735798) | Pamela Munster | 2016-04-01 |
| Radiosensitization of Multiple Brain Metastases Using AGuIX Gadolinium Based Nanoparticles (NCT02820454) | University Hospital, Grenoble | 2016-03-01 |
| High Dose Icotinib With Sequential SRS For NSCLC Patients Harboring EGFR Mutation With Brain Metastases (NCT02726568) | Betta Pharmaceuticals Co., Ltd. | 2016-03-01 |
| Preoperative Ceritinib (LDK378) in Glioblastoma Multiforme and CNS Metastasis (NCT02605746) | St. Joseph's Hospital and Medical Center, Phoenix | 2016-02-17 |
| Clinical Evaluation of the Treatment of Intellectual Metastases by Radiosurgery Gamma Knife by Means of a Support System by Mask. (NCT02732769) | Assistance Publique Hopitaux De Marseille | 2016-02-01 |
| Evaluation of Lucanthone to Whole Brain Radiation Therapy in Patients With Brain Metastases From Non-Small Cell Lung Cancer (NCT02014545) | Wake Forest University Health Sciences | 2016-01-01 |
| Pemetrexed/Platinum With or Without Bevacizumab in Brain Metastases From Patients With EGFR/ALK Negative Non-Squamous Non-small Cell Lung Cancer (NCT01951482) | Sun Yat-sen University | 2016-01-01 |
| HA-WBRT-SIB for Brain Metastasis of Lung Cancer (NCT06289023) | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 2016-01-01 |
| FSRT Combined With TMZ for Large BMs: a PSM Study (NCT03338075) | Chinese Academy of Medical Sciences | 2016-01-01 |
| Gefitinib With or Without Chemotherapy in Brain Metastases From Non-small Cell Lung Cancer (NCT01951469) | Sun Yat-sen University | 2016-01-01 |
| Treatment of Brain Metastases From Breast Cancer With Eribulin Mesylate (NCT02581839) | Case Comprehensive Cancer Center | 2015-11-17 |
| Comparing Immobilisation Shells in Cranial Radiotherapy (NCT02599142) | Royal Marsden NHS Foundation Trust | 2015-11-01 |
| Phase 2 Study of Study of Tesevatinib in Subjects With NSCLC and Brain or Leptomeningeal Metastases (NCT02616393) | Kadmon Corporation, LLC | 2015-11-01 |
| Hippocampal-sparing Whole Brain Radiotherapy for Brain Metastases From Breast Cancer (NCT03002532) | Affiliated Hospital to Academy of Military Medical Sciences | 2015-08-01 |
| Tumor Bed Hypofractionated IMRT After Surgery for Patients With Single,Large Brain Metastases From Solid Tumor (NCT02576522) | Istituto Clinico Humanitas | 2015-06-29 |
| Stereotactic Radiosurgery Dose Escalation for Brain Metastases (NCT02390518) | University of Utah | 2015-05-07 |
| A Study of Abemaciclib (LY2835219) in Participants With Breast Cancer, Non-small Cell Lung Cancer, or Melanoma That Has Spread to the Brain (NCT02308020) | Eli Lilly and Company | 2015-04-20 |
| Dose-Escalation Study of RRx-001 in Combination With Whole Brain Radiation in Subjects With Brain Metastases (NCT02215512) | EpicentRx, Inc. | 2015-02-06 |
| Anti-PD 1 Brain Collaboration for Patients With Melanoma Brain Metastases (NCT02374242) | Melanoma Institute Australia | 2014-11-04 |
| High-dose Pemetrexed to Treat Lung Adenocarcinoma With Brain Metastases (NCT02284490) | Rongjie Tao | 2014-11-01 |
| Comparator-Controlled Study for EGFR(+) Patients With Multiple BMs From NSCLC (BROKE) (EGFR-epidermal Growth Factor Receptor;BM-brain Metastases) (NCT02338011) | Shanghai Chest Hospital | 2014-11-01 |
| Fractionated Stereotactic Radiotherapy (FSRT) in Treatment of Brain Metastases (NCT02187822) | H. Lee Moffitt Cancer Center and Research Institute | 2014-10-09 |
| Whole Brain Radiotherapy Versus Volumetric Modulated Arc Therapy for Brain Metastases (NCT02220491) | British Columbia Cancer Agency | 2014-10-01 |
| Toronto BNB Pilot Study (NCT02082587) | University Health Network, Toronto | 2014-09-01 |
| Tomotherapy for Refractory Brain Metastases (NCT03027544) | Chinese Academy of Medical Sciences | 2014-09-01 |
| Tomotherapy as Primary Radiotherapy for Multipule Brain Metastases (NCT04178330) | Chinese Academy of Medical Sciences | 2014-09-01 |
| CNS and Extracranial Tumor Tissues, CSF, and Blood From Patients With Melanoma Brain Metastases (NCT02058953) | University of Pittsburgh | 2014-08-12 |
| STAR Cape+BKM120 MBC With Brain Met (NCT02000882) | US Oncology Research | 2014-05-29 |
| FLT PET/MR for Evaluation of Pseudoprogression in Patients With Brain Lesions (NCT02328300) | UNC Lineberger Comprehensive Cancer Center | 2014-05-07 |
| Bevacizumab, Etoposide and Cisplatin Followed by Whole Brain Radiotherapy in Breast Cancer With Brain Metastases (NCT02185352) | National Taiwan University Hospital | 2014-04-21 |
| GEM STUDY: Radiation And Yervoy in Patients With Melanoma and Brain Metastases (NCT02115139) | Grupo Español Multidisciplinar de Melanoma | 2014-04-04 |
| ANG1005 in Breast Cancer Patients With Recurrent Brain Metastases (NCT02048059) | Angiochem Inc | 2014-04-01 |
| Ipilimumab Induction in Patients With Melanoma Brain Metastases Receiving Stereotactic Radiosurgery (NCT02097732) | University of Michigan Rogel Cancer Center | 2014-04-01 |
| MK-3475 in Melanoma and NSCLC Patients With Brain Metastases (NCT02085070) | Yale University | 2014-03-01 |
| 18F-Fluorocholine (18F-FCho) to Distinguish Necrosis From Recurrence in Brain Metastases (NCT02037945) | Memorial Sloan Kettering Cancer Center | 2014-01-01 |
| Response of Brain Metastases After Gamma-Knife Radiosurgery Using Dynamic Susceptibility-weighted Contrast-enhanced Perfusion Magnetic Resonance Imaging (NCT02311556) | Washington University School of Medicine | 2013-05-07 |
| Improved Therapy Response Assessment in Metastatic Brain Tumors (NCT03458455) | Oslo University Hospital | 2013-03-01 |
| A Prospective Study of the Impact of Hippocampal Avoidance During Whole Brain Radiotherapy on Neurocognitive Function Decline (NCT02504788) | Chang Gung Memorial Hospital | 2013-01-18 |
| Hair-sparing Whole Brain Radiotherapy (NCT01421316) | University Hospital, Ghent | 2013-01-01 |
| A Single Arm Study of Neurocognitive Outcomes in Patients With Brain Metastases Managed With Stereotactic Radiosurgery (SRS) (NCT01821443) | University of California, San Francisco | 2012-12-01 |
| A Study of Fotemustine(FTM) Vs FTM and Ipilimumab (IPI) or IPI and Nivolumab in Melanoma Brain Metastasis (NCT02460068) | Italian Network for Tumor Biotherapy Foundation | 2012-12-01 |
| Neurocognitive Outcomes In Patients Treated With Radiotherapy For Five Or More Brain Metastases (NCT01731704) | University of California, San Francisco | 2012-12-01 |
| Whole Brain Radiotherapy (WBRT) With Sorafenib for Breast Cancer Brain Metastases (BCBM) (NCT01724606) | Memorial Sloan Kettering Cancer Center | 2012-11-05 |
| Erlotinib With Concurrent Brain Radiotherapy and Secondary Brain Radiotherapy After Recurrence With Erlotinib in NSCLC Non-increased-intracranial-pressure Symptomatic Brain Metastases (NCT01763385) | Wu Jieping Medical Foundation | 2012-11-01 |
| A Trial Evaluating Concurrent Whole Brain Radiotherapy and Iniparib in Multiple Non Operable Brain Metastases (NCT01551680) | Institut du Cancer de Montpellier - Val d'Aurelle | 2012-09-01 |
| Phase II Trial of Double Dose of Icotinib in Treating Brain Metastases From Non-small Cell Lung Cancer (NCT01688713) | Zhejiang Cancer Hospital | 2012-08-01 |
| PET/CT Evaluation of Primary and Metastatic Brain Tumors With a Novel Radioiodinated Phospholipid Ether Analogue I-NM404 (NCT01540513) | University of Wisconsin, Madison | 2012-03-01 |
| Erlotinib Plus Pemetrexed to Treat Lung Adenocarcinoma With Brain Metastases (NCT01578668) | Guangzhou Medical University | 2012-01-01 |
| PET/CT Imaging of Malignant Brain Tumors With 124I-NM404 (NCT01516905) | University of Wisconsin, Madison | 2011-12-01 |
| Icotinib Combined With WBRT For NSCLC Patients With Brain Metastases and EGFR Mutation (NCT01516983) | Betta Pharmaceuticals Co., Ltd. | 2011-12-01 |
| GRN1005 Alone or in Combination With Trastuzumab in Breast Cancer Patients With Brain Metastases (NCT01480583) | Angiochem Inc | 2011-10-01 |
| Stereotactic Radiotherapy Plus Temozolomide for Refractory Brain Metastases (NCT02654106) | Chinese Academy of Medical Sciences | 2011-10-01 |
| An Open-label, Phase I/IIa, Dose Escalating Study of 2B3-101 in Patients With Solid Tumors and Brain Metastases or Recurrent Malignant Glioma. (NCT01386580) | BBB-Therapeutics B.V. | 2011-07-01 |
| Continuous Endostar Infusion Combined With Radiotherapy in Patients With Brain Metastases (NCT01410370) | Jiangsu Simcere Pharmaceutical Co., Ltd. | 2011-06-01 |
| Electrochemotherapy as a Palliative Treatment for Brain Metastases (NCT01322100) | Copenhagen University Hospital at Herlev | 2011-04-01 |
| Phase I Dose Escalation in Patients With 1-3 Unresectable Brain Metastases (NCT02080949) | Barretos Cancer Hospital | 2011-01-01 |
| Genomic Study in Non-small Cell Lung Cancer Brain Metastasis (NCT04745715) | National Cheng-Kung University Hospital | 2011-01-01 |
| Bevacizumab With Etoposide and Cisplatin in Breast Cancer Patients With Brain and/or Leptomeningeal Metastasis (NCT01281696) | National Taiwan University Hospital | 2011-01-01 |
| Satraplatin in Children and Young Adults With Refractory Solid Tumors Including Brain Tumors (NCT01259479) | National Cancer Institute (NCI) | 2010-12-03 |