| Bipolar Efficacy Biomarkers for rTMS (NCT05393648) | University of California, San Diego | 2022-07-05 |
| Ketamine for Treatment-Resistant Bipolar Disorder (NCT05004896) | Joshua Rosenblat | 2022-07-04 |
| aiTBS for Relieving NSSI in Depressive Patients (NCT05384405) | Central South University | 2022-07-01 |
| Adjunctive Bright Light Therapy in Patients With Bipolar Depression and Eveningness (NCT05357313) | Chinese University of Hong Kong | 2022-06-02 |
| NRX-101 for Bipolar Depression With Subacute Suicidal Ideation (NCT03395392) | NeuroRx, Inc. | 2022-05-12 |
| Intensive TMS for Bipolar Depression (NCT05228457) | University of Pennsylvania | 2022-03-01 |
| Vortioxetine Adjunctive Treatment in Bipolar Depression (NCT05481957) | First Affiliated Hospital of Zhejiang University | 2022-03-01 |
| Pulse Width 0.15ms vs 0.30ms in Electroconvulsive Therapy (NCT05465915) | Charles University, Czech Republic | 2022-01-18 |
| Focused Ultrasound Amygdala Neuromodulation (NCT05228964) | University of Texas at Austin | 2022-01-13 |
| RTMS Feasibility Study on Adolescent Depression Stimulation (NCT06126198) | Uppsala University | 2022-01-01 |
| OSU6162 in Bipolar Depression (OBID) (NCT05296356) | Göteborg University | 2021-10-25 |
| Efficacy and Biomarkers of Response of TBS in Treatment Resistant Depression (NCT04998773) | Instituto de Investigacion Sanitaria La Fe | 2021-09-15 |
| Ketamine As an Adjunctive Therapy for Major Depression (2) (NCT04939649) | University of Dublin, Trinity College | 2021-09-13 |
| Treatment of Bipolar Depression With Pentoxifylline (NCT04417049) | University Health Network, Toronto | 2021-07-12 |
| EVALUATION OF BLOOD BIOMARKER-BASED DIAGNOSTIC AID IN OUTPATIENTS SUFFERING FROM DEPRESSION (NCT06369805) | Les Toises - Psychiatry and Psychotherapy Center | 2021-06-02 |
| Electro-Magnetic Convulsive Therapies for Depression: a Non-inferiority Study (NCT05054699) | University of Sao Paulo | 2021-05-31 |
| Brexpiprazole Treatment for Bipolar I Depression (NCT04569448) | Douglas Mental Health University Institute | 2021-05-10 |
| Naturalistic Study of Ketamine in the Treatment of Depression (NCT05249309) | Hospital de Clinicas de Porto Alegre | 2021-05-01 |
| University of Iowa Interventional Psychiatry Service Patient Registry (NCT04480918) | Mark Niciu | 2020-11-02 |
| PROSPECTIVE EVALUATION OF BLOOD BIOMARKERS AS AN AID TO DIAGNOSTIC AND TREATMENT IN DRUG-NAIVE PATIENTS WITH DEPRESSION (NCT06369792) | Les Toises - Psychiatry and Psychotherapy Center | 2020-10-20 |
| 8 Week Multi-site Study of MYDAYIS® for Bipolar Depression (NCT04235686) | Mayo Clinic | 2020-07-17 |
| Verification of the Reliability and Validity of THINC-it Tool in Bipolar Depression (NCT04471454) | Shanghai Mental Health Center | 2020-07-05 |
| Low Dose IL-2 Therapy in Patients With a Depressive Episode in the Course of a Bipolar Disorder (NCT04133233) | Assistance Publique - Hôpitaux de Paris | 2020-06-15 |
| Accelerated LFR for Bipolar Patients During the COVID-19 Pandemic (NCT04427137) | Centre for Addiction and Mental Health | 2020-06-09 |
| Delivering Electronic Cognitive Behavioural Therapy to Patients With Bipolar Disorder and Residual Depressive Symptoms (NCT04664257) | Dr. Nazanin Alavi | 2020-03-01 |
| Clinical Trial Evaluating Lumateperone Monotherapy in the Treatment of Bipolar Depression or Major Depressive Disorder (NCT04285515) | Intra-Cellular Therapies, Inc. | 2020-02-27 |
| 2-Year Study of Vagus Nerve Stimulation for Higher-Grade Treatment-Resistant Depression: Clinical Outcomes and Policy Recommendation (NCT07097025) | Dr.Yoav Domany | 2020-01-01 |
| Xenon Inhalation Therapy for Major Depressive Disorder and Bipolar Disorder (NCT03748446) | Massachusetts General Hospital | 2019-12-05 |
| A Naturalistic Study of Ketamine for Treatment Resistant Mood Disorders (NCT04226963) | Medical University of Gdansk | 2019-12-04 |
| NRX-101 for Maintenance of Remission From Severe Bipolar Depression in Patients With Suicidal Ideation (NCT03396068) | NeuroRx, Inc. | 2019-12-01 |
| Voice Changes During ECT (NCT04420793) | Medical University of South Carolina | 2019-11-07 |
| Bright Light Therapy in the Treatment of Non-seasonal Bipolar Depression (NCT03396744) | Assistance Publique - Hôpitaux de Paris | 2019-09-30 |
| Mechanism of Action of Electroconvulsive Therapy (NCT04059952) | Massachusetts General Hospital | 2019-06-28 |
| NRX100 vs. Placebo for Rapid Stabilization of Acute Suicidal Ideation and Behavior in Bipolar Depression (NCT03396601) | NeuroRx, Inc. | 2019-06-25 |
| Comparison of Physical and Virtual Sensory Room in an Inpatient Setting (NCT03918954) | Vastra Gotaland Region | 2019-05-01 |
| Efficacy, Safety and Pharmacokinetic Study of Inhaled Esketamine in Treatment-resistant Bipolar Depression (NCT03965871) | Celon Pharma SA | 2019-03-28 |
| Using Neuroplasticity-Based Computerized Training to Improve Emotion Regulation in Bipolar Disorder (BRAINS) (NCT05683431) | Rush University Medical Center | 2019-03-22 |
| 18F-DOPA PET to Elucidate the Antidepressant Mechanism of Lurasidone in Bipolar Disorder (NCT03902613) | New York State Psychiatric Institute | 2019-02-07 |
| Triple Chronotherapy in Adolescents (NCT03679962) | Billings Clinic | 2019-01-25 |
| Ketamine Associated ACC GABA and Glutamate Change and Depression Remission: (NCT03573349) | Mayo Clinic | 2019-01-03 |
| Probiotics to Prevent Relapse After Hospitalization for Bipolar Depression (NCT03349528) | Sheppard Pratt Health System | 2018-12-11 |
| NRX101 Glx Biomarker Validation Study (NCT03402152) | NeuroRx, Inc. | 2018-11-01 |
| Ketamine Versus Electroconvulsive Therapy in Depression (NCT03674671) | University of Ottawa | 2018-10-29 |
| Efficacy of Convulsive Therapies for Bipolar Depression (NCT03641300) | Centre for Addiction and Mental Health | 2018-09-21 |
| Behavioural Activation for Bipolar Depression: A Case Series (NCT03658824) | University of Exeter | 2018-09-01 |
| Continuous Theta Burst Stimulation as an add-on Treatment for Bipolar Depression (NCT03603561) | Universiteit Antwerpen | 2018-08-01 |
| Comparison of Two Forms of Oxcarbazepine for the Treatment of Bipolar Depression (NCT03567681) | Collaborative Care Initiative, LLC | 2018-06-13 |
| Low Field Magnetic Stimulation: Imaging Biomarkers in Geriatric Bipolar Depression (NCT03484494) | Mclean Hospital | 2018-05-29 |
| Sequential Therapy for the Treatment of Severe Bipolar Depression. (NCT02974010) | NeuroRx, Inc. | 2018-01-15 |
| Safety and Efficacy of Fecal Microbiota Transplantation in a Population With Bipolar Disorder (NCT03279224) | Valerie Taylor | 2018-01-01 |
| Lithium Effects on the Brain's Functional and Structural Connectome in the Treatment of Bipolar Disorder (NCT03336918) | Brigham and Women's Hospital | 2017-12-07 |
| Lumateperone Monotherapy for the Treatment of Bipolar Depression Conducted Globally (NCT03249376) | Intra-Cellular Therapies, Inc. | 2017-11-27 |
| Cannabidiol as an Adjunctive Treatment for Bipolar Depression (NCT03310593) | Hospital de Clinicas de Porto Alegre | 2017-11-01 |
| Ketamine as an Adjunctive Therapy for Major Depression (NCT03256162) | St Patrick's Hospital, Ireland | 2017-09-07 |
| Effects of Erythropoietin for Cognitive Side-effects of ECT (NCT03339596) | Martin Balslev Jørgensen | 2017-06-26 |
| Brexpiprazole for Bipolar Depression (NCT03427892) | University of Texas Southwestern Medical Center | 2017-03-01 |
| The Study of Effectiveness of rTMS on Rumination and Anhedonia in Patients With Major Depressive Disorder (NCT03468686) | University of Tehran | 2016-12-21 |
| Efficacy of rTMS in Bipolar Depression (NCT02749006) | University of British Columbia | 2016-10-05 |
| Minocycline and Celecoxib as Adjunctive Treatments of Bipolar Depression (NCT02703363) | Pakistan Institute of Living and Learning | 2016-08-01 |
| NeoSync TMS Treatment for Bipolar I Depression (NCT02839798) | Butler Hospital | 2016-05-01 |
| Clinical Trial Evaluating ITI-007 as an Adjunctive Therapy to Lithium or Valproate for the Treatment of Bipolar Depression (NCT02600507) | Intra-Cellular Therapies, Inc. | 2016-03-07 |
| Effect of Ketamine vs. Active Placebo on Suicidal Ideation in Depressed Inpatients With Major Depressive Disorder or Bipolar Depression. (NCT02593643) | Sunnybrook Health Sciences Centre | 2016-01-01 |
| Clinical Trial Evaluating ITI-007 (Lumateperone) as a Monotherapy for the Treatment of Bipolar Depression (NCT02600494) | Intra-Cellular Therapies, Inc. | 2015-12-15 |
| An Open Label Trial of TMS Therapy for Bipolar Depression (NCT02640950) | Sheppard Pratt Health System | 2015-12-01 |
| Cytidine- and Creatine-Containing Drug in Treating Bipolar Depression (NCT01543139) | Ewha Womans University | 2015-12-01 |
| 12-Week Study Evaluating the Efficacy, Safety, and Tolerability of Adjunctive Infliximab for Bipolar I/II Depression (NCT02363738) | University Health Network, Toronto | 2015-09-01 |
| Jump Step - A Participatory Approach to Physical Activity & Mental Wellness (NCT02549547) | University of British Columbia | 2015-08-01 |
| Study to Evaluate the Effects of Switching Different Strength Forms of FK949E in Bipolar Disorder Patients With Major Depressive Episodes (NCT02362412) | Astellas Pharma Inc | 2015-02-18 |
| Biosignatures of Latuda for Bipolar Depression (NCT02239094) | New York State Psychiatric Institute | 2015-01-01 |
| Chronotherapy Randomized Controlled Trial (NCT02176824) | Medical University of South Carolina | 2014-06-01 |
| A Prophylactic Trial of Omega-3 Polyunsaturated Fatty Acids in Bipolar Disorder (NCT04210804) | National University of Ireland, Galway, Ireland | 2014-04-01 |
| A Phase III Study of SM-13496 in Patients With Bipolar I Depression. (NCT01986101) | Sumitomo Pharma Co., Ltd. | 2014-02-19 |
| Neural and Visual Responses to Light in Bipolar Disorder: A Novel Putative Biomarker (NCT02048995) | Northwestern University | 2014-02-01 |
| Treatment of Bipolar Depression With H1-Coil Deep Brain rTMS: Clinical-Cognitive and Safety Evaluation (NCT01962350) | University of Sao Paulo | 2014-02-01 |
| Feasibility and Tolerability of Adjunct Chronotherapy in Depressed Inpatients (NCT02088580) | Medical University of South Carolina | 2013-10-01 |
| Pediatric Open-Label Extension Study (NCT01914393) | Sumitomo Pharma America, Inc. | 2013-09-30 |
| Asenapine for Bipolar Depression (NCT01807741) | University of Cincinnati | 2013-09-01 |
| Uridine Adolescent Bipolar Depression Randomized Controlled Trial (NCT01805440) | University of Utah | 2013-08-01 |
| Multiple Treatment Study Using Low Field Magnetic Stimulation for Bipolar Depression (NCT01929681) | Mclean Hospital | 2013-07-01 |
| Vitamin D Supplementation for Bipolar Depression (NCT01884844) | University of Massachusetts, Worcester | 2013-06-01 |
| The Safety and Effectiveness of Probiotic Supplementation on Bipolar Depression (NCT02155972) | Women's College Hospital | 2013-05-01 |
| Trial of Ketamine and Lithium Therapy in Bipolar Depression (NCT01768767) | Yale University | 2013-01-01 |
| Investigating tDCS as a Treatment for Unipolar and Bipolar Depression (NCT01562184) | The University of New South Wales | 2012-06-01 |
| Repetitive Transcranial Magnetic Stimulation for Treating Resistant Bipolar Depression (NCT01586793) | Douglas Mental Health University Institute | 2012-05-01 |
| Safety and Efficacy Study of Deep Transcranial Magnetic Stimulation in Bipolar Depression (NCT01566591) | Brainsway | 2012-05-01 |
| PET and MRI Brain Imaging of Bipolar Disorder (NCT01880957) | Stony Brook University | 2011-11-08 |
| Exploring the Effects of Coenzyme Q10 on Bioenergetics Metabolism in Geriatric Bipolar Depression (NCT01390389) | Mclean Hospital | 2011-07-01 |
| Evaluating the Efficacy of Adjunctive Minocycline for the Treatment of Bipolar Depression (NCT01403662) | University Health Network, Toronto | 2011-07-01 |
| Minocycline for Bipolar Depression (NCT01514422) | Icahn School of Medicine at Mount Sinai | 2011-05-01 |
| Cyclooxygenase-2-Inhibitor Combination Treatment for Bipolar Depression (NCT01479829) | Loyola University | 2011-03-23 |
| Functional Assessment of Patients With Acute Bipolar Depression After 8 Months of Follow-up (NCT01255982) | AstraZeneca | 2011-03-01 |
| Effect of Intermittent ThetaBurst Stimulation in Treatment-resistant Bipolar Depression (NCT02740244) | Hôpital le Vinatier | 2011-01-01 |
| Evaluate the Efficacy and Safety of Quetiapine Fumarate (SEROQUEL) Extended Release as Monotherapy in the Treatment of Patients With Bipolar Depression (NCT01256177) | AstraZeneca | 2010-12-01 |
| Lurasidone HCI - A 6-week Phase 3 Study of Patients With Bipolar I Depression (NCT01284517) | Sumitomo Pharma America, Inc. | 2010-11-01 |
| Neurophysiologic Changes in Patients With Bipolar Depression (NCT01213121) | Seoul National University Bundang Hospital | 2010-09-01 |
| Longitudinal Study on the Neuroprotective and Neurotrophic Effects of Lithium (NCT01919892) | University of Sao Paulo | 2010-09-01 |
| Efficacy of Quetiapine XR Versus Divalproex on Clinical Outcome Quality of Sleep and Quality of Life in Bipolar Depression (NCT01587066) | Bo-Hyun Yoon | 2010-08-01 |
| Low Field Magnetic Stimulation (LFMS) in Mood Disorders: 6 Treatments (NCT01557192) | Mclean Hospital | 2010-05-01 |
| Neuroimaging Studies of the Treatment of Bipolar Depression With Citalopram (NCT01639482) | Massachusetts General Hospital | 2010-04-01 |
| Use of Ketamine to Enhance Electroconvulsive Therapy (ECT) in Depression (NCT01309581) | James Murrough | 2010-04-01 |